Výsledky vyhledávání - Carlos Garcı́a-Echeverrı́a

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  1. 1
    Inhibitors of the p53/hdm2 protein–protein interaction—path to the clinic

    Inhibitors of the p53/hdm2 protein–protein interaction—path to the clinic Autor Jean‐Christophe Carry, Carlos Garcı́a-Echeverrı́a

    Vydáno 2013
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  2. 2
    Antibody–drug conjugates—A new wave of cancer drugs

    Antibody–drug conjugates—A new wave of cancer drugs Autor Hervé Bouchard, Christian Viskov, Carlos Garcı́a-Echeverrı́a

    Vydáno 2014
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  3. 3
    Activity of a novel, dual PI3-kinase/mTor inhibitor NVP-BEZ235 against primary human pancreatic cancers grown as orthotopic xenografts

    Activity of a novel, dual PI3-kinase/mTor inhibitor NVP-BEZ235 against primary human pancreatic cancers grown as orthotopic xenografts Autor Peng Cao, S-M Maira, Carlos Garcı́a-Echeverrı́a, David W. Hedley

    Vydáno 2009
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  4. 4
    Antennapedia and HIV Transactivator of Transcription (TAT) “Protein Transduction Domains” Promote Endocytosis of High Molecular Weight Cargo upon Binding to Cell Surface Glycosaminoglycans

    Antennapedia and HIV Transactivator of Transcription (TAT) “Protein Transduction Domains” Promote Endocytosis of High Molecular Weight Cargo upon Binding to Cell Surface Glycosamin... Autor Sandra Console, Cornelia Marty, Carlos Garcı́a-Echeverrı́a, Reto A. Schwendener, Kurt Ballmer‐Hofer

    Vydáno 2003
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  5. 5
    Development of Ewing's Sarcoma from Primary Bone Marrow–Derived Mesenchymal Progenitor Cells

    Development of Ewing's Sarcoma from Primary Bone Marrow–Derived Mesenchymal Progenitor Cells Autor Nicolò Riggi, Luisa Cironi, Paolo Provero, Mario-Luca Suvà, Konstantinos Kaloulis, Carlos Garcı́a-Echeverrı́a, Francesco Hoffmann, Andreas Trumpp, Ivan Stamenkovic

    Vydáno 2005
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  6. 6
    The role of PTEN/Akt/PI3K signaling in the maintenance and viability of prostate cancer stem-like cell populations

    The role of PTEN/Akt/PI3K signaling in the maintenance and viability of prostate cancer stem-like cell populations Autor Anna Dubrovska, Sungeun Kim, Richard J. Salamone, John R. Walker, Sauveur-Michel Maira, Carlos Garcı́a-Echeverrı́a, Peter G. Schultz, Venkateshwar A. Reddy

    Vydáno 2008
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  7. 7
    Specific apoptosis induction by the dual PI3K/mTor inhibitor NVP-BEZ235 in HER2 amplified and PIK3CA mutant breast cancer cells

    Specific apoptosis induction by the dual PI3K/mTor inhibitor NVP-BEZ235 in HER2 amplified and PIK3CA mutant breast cancer cells Autor Saskia M. Brachmann, Irmgard Hofmann, Christian Schnell, Christine Fritsch, Susan Wee, Heidi A. Lane, Shaowen Wang, Carlos Garcı́a-Echeverrı́a, Sauveur-Michel Maira

    Vydáno 2009
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  8. 8
    Preclinical <i>In vivo</i> Study of New Insulin-Like Growth Factor-I Receptor–Specific Inhibitor in Ewing's Sarcoma

    Preclinical <i>In vivo</i> Study of New Insulin-Like Growth Factor-I Receptor–Specific Inhibitor in Ewing's Sarcoma Autor Maria Cristina Manara, Lorena Landuzzi, Patrizia Nanni, Giordano Nicoletti, Diana Zambelli, Pier‐Luigi Lollini, Cristina Nanni, Francesco Hofmann, Carlos Garcı́a-Echeverrı́a, Piero Picci, Katia Scotlandi

    Vydáno 2007
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  9. 9
    Targeting Melanoma with Dual Phosphoinositide 3-Kinase/Mammalian Target of Rapamycin Inhibitors

    Targeting Melanoma with Dual Phosphoinositide 3-Kinase/Mammalian Target of Rapamycin Inhibitors Autor Romina Marone, Dominik Erhart, Ann C. Mertz, Thomas Bohnacker, Christian Schnell, Vladimir Cmiljanović, Frédéric Stauffer, Carlos Garcı́a-Echeverrı́a, Bernd Giese, Sauveur-Michel Maira, Matthias P. Wymann

    Vydáno 2009
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  10. 10
    Hyperactivation of phosphatidylinositol-3 kinase promotes escape from hormone dependence in estrogen receptor–positive human breast cancer

    Hyperactivation of phosphatidylinositol-3 kinase promotes escape from hormone dependence in estrogen receptor–positive human breast cancer Autor Todd W. Miller, Bryan T. Hennessy, Ana M. González-Angulo, Emily M. Fox, Gordon B. Mills, Heidi Chen, Catherine Higham, Carlos Garcı́a-Echeverrı́a, Yu Shyr, Carlos L. Arteaga

    Vydáno 2010
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  11. 11
    NVP-AUY922: a small molecule HSP90 inhibitor with potent antitumor activity in preclinical breast cancer models

    NVP-AUY922: a small molecule HSP90 inhibitor with potent antitumor activity in preclinical breast cancer models Autor Michael Rugaard Jensen, Joseph Schoepfer, Thomas Radimerski, Andrew J. Massey, Chantale T. Guy, Josef Brueggen, Cornelia Quadt, Alan Buckler, Robert Cozens, Martin J. Drysdale, Carlos Garcı́a-Echeverrı́a, Patrick Chêne

    Vydáno 2008
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  12. 12
    NVP-BEZ235 as a New Therapeutic Option for Sarcomas

    NVP-BEZ235 as a New Therapeutic Option for Sarcomas Autor Maria Cristina Manara, Giordano Nicoletti, Diana Zambelli, Selena Ventura, Clara Guerzoni, Lorena Landuzzi, Pier‐Luigi Lollini, Saveur-Michel Maira, Carlos Garcı́a-Echeverrı́a, Mario Mercuri, Piero Picci, Katia Scotlandi

    Vydáno 2010
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  13. 13
    Antitumor Activity of the Insulin-Like Growth Factor-I Receptor Kinase Inhibitor NVP-AEW541 in Musculoskeletal Tumors

    Antitumor Activity of the Insulin-Like Growth Factor-I Receptor Kinase Inhibitor NVP-AEW541 in Musculoskeletal Tumors Autor Katia Scotlandi, Maria Cristina Manara, Giordano Nicoletti, Pier‐Luigi Lollini, Stella Lukas, Stefania Benini, Stefania Croci, Stefania Perdichizzi, Diana Zambelli, Massimo Serra, Carlos García-Echeverría, Francesco Hofmann, Piero Picci

    Vydáno 2005
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  14. 14
    Exploring amyloid formation by a <i>de novo</i> design

    Exploring amyloid formation by a <i>de novo</i> design Autor Richard A. Kammerer, Dirk Kostrewa, Jesús Zurdo, A. Detken, Carlos Garcı́a-Echeverrı́a, Janelle D. Green, Shirley A. Müller, Beat H. Meier, Fritz K. Winkler, Christopher M. Dobson, Michel O. Steinmetz

    Vydáno 2004
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  15. 15
    Effects of the Dual Phosphatidylinositol 3-Kinase/Mammalian Target of Rapamycin Inhibitor NVP-BEZ235 on the Tumor Vasculature: Implications for Clinical Imaging

    Effects of the Dual Phosphatidylinositol 3-Kinase/Mammalian Target of Rapamycin Inhibitor NVP-BEZ235 on the Tumor Vasculature: Implications for Clinical Imaging Autor Christian Schnell, Frédéric Stauffer, Peter R. Allegrini, Terence O’Reilly, Paul M.J. McSheehy, Celine Dartois, Michael Stumm, Robert Cozens, Amanda Littlewood‐Evans, Carlos García-Echeverría, Sauveur-Michel Maira

    Vydáno 2008
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  16. 16
    FGFR2 Promotes Breast Tumorigenicity through Maintenance of Breast Tumor-Initiating Cells

    FGFR2 Promotes Breast Tumorigenicity through Maintenance of Breast Tumor-Initiating Cells Autor Sungeun Kim, Anna Dubrovska, Richard J. Salamone, John R. Walker, Kathryn B. Grandinetti, Ghislain M. C. Bonamy, Anthony P. Orth, Jimmy Elliott, Diana Graus Porta, Carlos Garcı́a-Echeverrı́a, Venkateshwar A. Reddy

    Vydáno 2013
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  17. 17
    Preclinical Antitumor Activity of the Orally Available Heat Shock Protein 90 Inhibitor NVP-BEP800

    Preclinical Antitumor Activity of the Orally Available Heat Shock Protein 90 Inhibitor NVP-BEP800 Autor Andrew J. Massey, Joseph Schoepfer, Paul A. Brough, Josef Brueggen, Patrick Chêne, Martin J. Drysdale, Ulrike Pfaar, Thomas Radimerski, Stephan Ruetz, Alain Schweitzer, Mike Wood, Carlos Garcı́a-Echeverrı́a, Michael Rugaard Jensen

    Vydáno 2010
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  18. 18
    Differential induction of apoptosis in HER2 and EGFR addicted cancers following PI3K inhibition

    Differential induction of apoptosis in HER2 and EGFR addicted cancers following PI3K inhibition Autor Anthony C. Faber, Danan Li, Young-Chul Song, Mei‐Chih Liang, Beow Y. Yeap, Roderick T. Bronson, Eugene Lifshits, Chen Zhao, Sauveur-Michel Maira, Carlos Garcı́a-Echeverrı́a, Kwok‐Kin Wong, Jeffrey A. Engelman

    Vydáno 2009
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  19. 19
    Combination Therapy Targeting Both Tumor-Initiating and Differentiated Cell Populations in Prostate Carcinoma

    Combination Therapy Targeting Both Tumor-Initiating and Differentiated Cell Populations in Prostate Carcinoma Autor Anna Dubrovska, Jimmy Elliott, Richard J. Salamone, Sungeun Kim, Lindsey J. Aimone, John R. Walker, J. P. Watson, Sauveur-Michel Maira, Carlos Garcı́a-Echeverrı́a, Charles Y. Cho, Venkateshwar A. Reddy, Peter G. Schultz

    Vydáno 2010
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  20. 20
    Antimyeloma Activity of the Orally Bioavailable Dual Phosphatidylinositol 3-Kinase/Mammalian Target of Rapamycin Inhibitor NVP-BEZ235

    Antimyeloma Activity of the Orally Bioavailable Dual Phosphatidylinositol 3-Kinase/Mammalian Target of Rapamycin Inhibitor NVP-BEZ235 Autor Douglas W. McMillin, Melissa Ooi, Jake Delmore, Joseph Negri, Patrick Hayden, Nicholas Mitsiades, Jana Jakubı́ková, Sauveur-Michel Maira, Carlos Garcı́a-Echeverrı́a, Robert Schlossman, Nikhil C. Munshi, Paul G. Richardson, Kenneth C. Anderson, Constantine S. Mitsiades

    Vydáno 2009
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