Resultados da pesquisa - Carlo Leonetti

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  1. 1
    Patient-derived xenografts: a relevant preclinical model for drug development

    Patient-derived xenografts: a relevant preclinical model for drug development Por Luca Pompili, Manuela Porru, Carla Caruso, Annamaria Biroccio, Carlo Leonetti

    Publicado em 2016
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  2. 2
    Targeting KRAS in metastatic colorectal cancer: current strategies and emerging opportunities

    Targeting KRAS in metastatic colorectal cancer: current strategies and emerging opportunities Por Manuela Porru, Luca Pompili, Carla Caruso, Annamaria Biroccio, Carlo Leonetti

    Publicado em 2018
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  3. 3
    Dual-specificity phosphatase DUSP6 has tumor-promoting properties in human glioblastomas

    Dual-specificity phosphatase DUSP6 has tumor-promoting properties in human glioblastomas Por Samantha Messina, Luigi Frati, Carlo Leonetti, Candida Zuchegna, Erika Di Zazzo, Antonella Calogero, Antonio Porcellini

    Publicado em 2011
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  4. 4
    Combined treatment with temozolomide and poly(ADP-ribose) polymerase inhibitor enhances survival of mice bearing hematologic malignancy at the central nervous system site

    Combined treatment with temozolomide and poly(ADP-ribose) polymerase inhibitor enhances survival of mice bearing hematologic malignancy at the central nervous system site Por Lucio Tentori, Carlo Leonetti, Marco Scarsella, Giulia d’Amati, Ilaria Portarena, Gabriella Zupi, Enzo Bonmassar, Grazia Graziani

    Publicado em 2002
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  5. 5
    Restoring p53 active conformation by zinc increases the response of mutant p53 tumor cells to anticancer drugs

    Restoring p53 active conformation by zinc increases the response of mutant p53 tumor cells to anticancer drugs Por Rosa Puca, Lavinia Nardinocchi, Manuela Porru, Amos J. Simon, Gideon Rechavi, Carlo Leonetti, David Givol, Gabriella D’Orazi

    Publicado em 2011
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  6. 6
    Evaluation of the in vitro and in vivo antiangiogenic effects of denosumab and zoledronic acid

    Evaluation of the in vitro and in vivo antiangiogenic effects of denosumab and zoledronic acid Por Gabriella Misso, Manuela Porru, Antonella Stoppacciaro, M. A. Castellano, Federica de Cicco, Carlo Leonetti, Daniele Santini, Michele Caraglia

    Publicado em 2012
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  7. 7
    Antitumor Effect of c-myc Antisense Phosphorothioate Oligodeoxynucleotides on Human Melanoma Cells In Vitro and in Mice

    Antitumor Effect of c-myc Antisense Phosphorothioate Oligodeoxynucleotides on Human Melanoma Cells In Vitro and in Mice Por Carlo Leonetti, Igea D' Agnano, Francesco Lozupone, Alessandra Valentini, Tim Geiser, Gerald Zon, Bruno Calabretta, Gennaro Citro, Gabriella Zupi

    Publicado em 1996
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  8. 8
    Cathepsin B inhibition interferes with metastatic potential of human melanoma: an in vitro and in vivo study

    Cathepsin B inhibition interferes with metastatic potential of human melanoma: an in vitro and in vivo study Por Paola Matarrese, Barbara Ascione, Laura Ciarlo, Rosa Vona, Carlo Leonetti, Marco Scarsella, Anna Maria Mileo, Caterina Catricalà, Marco G. Paggi, Walter Malorni

    Publicado em 2010
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  9. 9
    A fluorescent curcumin-based Zn(II)-complex reactivates mutant (R175H and R273H) p53 in cancer cells

    A fluorescent curcumin-based Zn(II)-complex reactivates mutant (R175H and R273H) p53 in cancer cells Por Alessia Garufi, Daniela Trisciuoglio, Manuela Porru, Carlo Leonetti, Antonella Stoppacciaro, Valerio D’Orazi, Maria Laura Avantaggiati, Alessandra Crispini, Daniela Pucci, Gabriella D’Orazi

    Publicado em 2013
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  10. 10
    Medical treatment of orthotopic glioblastoma with transferrin-conjugated nanoparticles encapsulating zoledronic acid

    Medical treatment of orthotopic glioblastoma with transferrin-conjugated nanoparticles encapsulating zoledronic acid Por Manuela Porru, Silvia Zappavigna, Giuseppina Salzano, Amalia Luce, Antonella Stoppacciaro, Maria Luisa Balestrieri, Simona Artuso, Sara Lusa, Giuseppe De Rosa, Carlo Leonetti, Michele Caraglia

    Publicado em 2014
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  11. 11
    Stabilization of quadruplex DNA perturbs telomere replication leading to the activation of an ATR-dependent ATM signaling pathway

    Stabilization of quadruplex DNA perturbs telomere replication leading to the activation of an ATR-dependent ATM signaling pathway Por Angela Rizzo, Erica Salvati, Manuela Porru, Carmen D’Angelo, Malcolm F. G. Stevens, Maurizio D’Incalci, Carlo Leonetti, Éric Gilson, Gabriella Zupi, Annamaria Biroccio

    Publicado em 2009
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  12. 12
    Zinc Downregulates HIF-1α and Inhibits Its Activity in Tumor Cells In Vitro and In Vivo

    Zinc Downregulates HIF-1α and Inhibits Its Activity in Tumor Cells In Vitro and In Vivo Por Lavinia Nardinocchi, Valentina Pantisano, Rosa Puca, Manuela Porru, Aurora Aiello, Annalisa Grasselli, Carlo Leonetti, Michal Safran, Gideon Rechavi, David Givol, Antonella Farsetti, Gabriella D’Orazi

    Publicado em 2010
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  13. 13
    Reversible Dysfunction of Wild-Type p53 following Homeodomain-Interacting Protein Kinase-2 Knockdown

    Reversible Dysfunction of Wild-Type p53 following Homeodomain-Interacting Protein Kinase-2 Knockdown Por Rosa Puca, Lavinia Nardinocchi, Hilah Gal, Gideon Rechavi, Ninette Amariglio, Eytan Domany, Daniel A. Notterman, Marco Scarsella, Carlo Leonetti, Ada Sacchi, Giovanni Blandino, David Givol, Gabriella D’Orazi

    Publicado em 2008
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  14. 14
    Sema6A and Mical1 control cell growth and survival of BRAFV600E human melanoma cells

    Sema6A and Mical1 control cell growth and survival of BRAFV600E human melanoma cells Por Rossella Loria, Giulia Bon, Valentina Perotti, Enzo Gallo, Ilaria Bersani, Paola Baldassari, Manuela Porru, Carlo Leonetti, Selene E. Di Carlo, Paolo Visca, Maria Felice Brizzi, Andrea Anichini, Roberta Mortarini, Rita Falcioni

    Publicado em 2014
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  15. 15
    Pharmacological activation of SIRT6 triggers lethal autophagy in human cancer cells

    Pharmacological activation of SIRT6 triggers lethal autophagy in human cancer cells Por Sara Iachettini, Daniela Trisciuoglio, Dante Rotili, Alessia Lucidi, Erica Salvati, Pasquale Zizza, Luca Di Leo, Donatella Del Bufalo, Maria Rosa Ciriolo, Carlo Leonetti, Clemens Steegborn, Antonello Mai, Angela Rizzo, Annamaria Biroccio

    Publicado em 2018
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  16. 16
    Intragenic G-quadruplex structure formed in the human CD133 and its biological and translational relevance

    Intragenic G-quadruplex structure formed in the human CD133 and its biological and translational relevance Por Pasquale Zizza, Chiara Cingolani, Simona Artuso, Erica Salvati, Angela Rizzo, Carmen D’Angelo, Manuela Porru, Bruno Pagano, Jussara Amato, Antonio Randazzo, Ettore Novellino, Antonella Stoppacciaro, Éric Gilson, Giorgio Stassi, Carlo Leonetti, Annamaria Biroccio

    Publicado em 2015
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  17. 17
    Evidence for G-quadruplex in the promoter of vegfr-2 and its targeting to inhibit tumor angiogenesis

    Evidence for G-quadruplex in the promoter of vegfr-2 and its targeting to inhibit tumor angiogenesis Por Erica Salvati, Pasquale Zizza, Angela Rizzo, Sara Iachettini, Chiara Cingolani, Carmen D’Angelo, Manuela Porru, Antonio Randazzo, Bruno Pagano, Ettore Novellino, Maria Elena Pisanu, Antonella Stoppacciaro, Francesca Spinella, Anna Bagnato, Éric Gilson, Carlo Leonetti, Annamaria Biroccio

    Publicado em 2013
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  18. 18
    Telomere damage induced by the G-quadruplex ligand RHPS4 has an antitumor effect

    Telomere damage induced by the G-quadruplex ligand RHPS4 has an antitumor effect Por Erica Salvati, Carlo Leonetti, Angela Rizzo, Marco Scarsella, Marcella Mottolese, Rossella Galati, Isabella Sperduti, Malcolm F. G. Stevens, Maurizio D’Incalci, Marı́a A. Blasco, Giovanna Chiorino, Serge Bauwens, Béatrice Horard, Éric Gilson, Antonella Stoppacciaro, Gabriella Zupi, Annamaria Biroccio

    Publicado em 2007
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  19. 19
    Cancer cells induce immune escape via glycocalyx changes controlled by the telomeric protein <scp>TRF</scp> 2

    Cancer cells induce immune escape via glycocalyx changes controlled by the telomeric protein <scp>TRF</scp> 2 Por Julien Cherfils‐Vicini, Charlène Iltis, Ludovic Cervera, Sabrina Pisano, Olivier Croce, Nori Sadouni, Balázs Győrffy, Romy Collet, Valérie M. Renault, Martin Rey‐Millet, Carlo Leonetti, Pasquale Zizza, Fabrice Allain, François Ghiringhelli, Nicolas Soubeiran, Marina Shkreli, Éric Vivier, Annamaria Biroccio, Éric Gilson

    Publicado em 2019
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  20. 20
    <scp>MiR</scp> ‐182‐3p targets <scp>TRF2</scp> and impairs tumor growth of triple‐negative breast cancer

    <scp>MiR</scp> ‐182‐3p targets <scp>TRF2</scp> and impairs tumor growth of triple‐negative breast cancer Por Roberto Dinami, Luca Pompili, Eleonora Petti, Manuela Porru, Carmen D’Angelo, Serena Di Vito, Angela Rizzo, Virginia Campani, Giuseppe De Rosa, Alejandra Bruna, Violeta Serra, Miguel Mano, Mauro Giacca, Carlo Leonetti, Gennaro Ciliberto, Madalena Tarsounas, Antonella Stoppacciaro, Stefan Schoeftner, Annamaria Biroccio

    Publicado em 2022
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