Výsledky vyhledávání - Caddick, Stephen

Next-generation disulfide stapling: reduction and functional re-bridging all in one Autor Lee, Maximillian T. W., Maruani, Antoine, Baker, James R., Caddick, Stephen, Chudasama, Vijay

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Bioconjugation of Green Fluorescent Protein via an Unexpectedly Stable Cyclic Sulfonium Intermediate Autor Nathani, Ramiz, Moody, Paul, Smith, Mark E B, Fitzmaurice, Richard J, Caddick, Stephen

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A novel synthetic chemistry approach to linkage-specific ubiquitin conjugation Autor Morgan, Rachel E., Chudasama, Vijay, Moody, Paul, Smith, Mark E. B., Caddick, Stephen

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Cysteine Promoted C-Terminal Hydrazinolysis of Native Peptides and Proteins** Autor Adams, Anna L, Cowper, Ben, Morgan, Rachel E, Premdjee, Bhavesh, Caddick, Stephen, Macmillan, Derek

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The design, synthesis and pharmacological characterization of novel β(2)-adrenoceptor antagonists Autor Hothersall, J Daniel, Black, James, Caddick, Stephen, Vinter, Jeremy G, Tinker, Andrew, Baker, James R

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A plug-and-play approach to antibody-based therapeutics via a chemoselective dual click strategy Autor Maruani, Antoine, Smith, Mark E.B., Miranda, Enrique, Chester, Kerry A., Chudasama, Vijay, Caddick, Stephen

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Enabling the controlled assembly of antibody conjugates with a loading of two modules without antibody engineering Autor Lee, Maximillian T. W., Maruani, Antoine, Richards, Daniel A., Baker, James R., Caddick, Stephen, Chudasama, Vijay

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A novel approach to the site-selective dual labelling of a protein via chemoselective cysteine modification Autor Nathani, Ramiz I., Moody, Paul, Chudasama, Vijay, Smith, Mark E. B., Fitzmaurice, Richard J., Caddick, Stephen

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Inhibition of HIV-1 Replication by Isoxazolidine and Isoxazole Sulfonamides Autor Loh, Belinda, Vozzolo, Luciano, Mok, B James, Lee, Chien Chi, Fitzmaurice, Richard J, Caddick, Stephen, Fassati, Ariberto

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A rapid, site-selective and efficient route to the dual modification of DARPins Autor Moody, Paul, Chudasama, Vijay, Nathani, Ramiz I., Maruani, Antoine, Martin, Stephen, Smith, Mark E. B., Caddick, Stephen

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Bromomaleimide-Linked Bioconjugates Are Cleavable in Mammalian Cells Autor Moody, Paul, Smith, Mark E B, Ryan, Chris P, Chudasama, Vijay, Baker, James R, Molloy, Justin, Caddick, Stephen

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Bromopyridazinedione-mediated protein and peptide bioconjugation Autor Chudasama, Vijay, Smith, Mark E. B., Schumacher, Felix F., Papaioannou, Danai, Waksman, Gabriel, Baker, James R., Caddick, Stephen

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In Situ Maleimide Bridging of Disulfides and a New Approach to Protein PEGylation Autor Schumacher, Felix F., Nobles, Muriel, Ryan, Chris P., Smith, Mark E. B., Tinker, Andrew, Caddick, Stephen, Baker, James R.

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Optical control of trimeric P2X receptors and acid-sensing ion channels Autor Browne, Liam E., Nunes, João P. M., Sim, Joan A., Chudasama, Vijay, Bragg, Laricia, Caddick, Stephen, Alan North, R.

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Highly homogeneous antibody modification through optimisation of the synthesis and conjugation of functionalised dibromopyridazinediones Autor Bahou, Calise, Richards, Daniel A., Maruani, Antoine, Love, Elizabeth A., Javaid, Faiza, Caddick, Stephen, Baker, James R., Chudasama, Vijay

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Evaluating the use of Apo-neocarzinostatin as a cell penetrating protein Autor Moody, Paul, Burlina, Fabienne, Martin, Stephen R., Morgan, Rachel E., Offer, John, Smith, Mark E.B., Molloy, Justin E., Caddick, Stephen

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Protein Modification, Bioconjugation, and Disulfide Bridging Using Bromomaleimides Autor Smith, Mark E. B., Schumacher, Felix F., Ryan, Chris P., Tedaldi, Lauren M., Papaioannou, Danai, Waksman, Gabriel, Caddick, Stephen, Baker, James R.

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Tunable reagents for multi-functional bioconjugation: reversible or permanent chemical modification of proteins and peptides by control of maleimide hydrolysis Autor Ryan, Chris P., Smith, Mark E. B., Schumacher, Felix F., Grohmann, Dina, Papaioannou, Danai, Waksman, Gabriel, Werner, Finn, Baker, James R., Caddick, Stephen

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Acid-cleavable thiomaleamic acid linker for homogeneous antibody–drug conjugation Autor Castañeda, Lourdes, Maruani, Antoine, Schumacher, Felix F., Miranda, Enrique, Chudasama, Vijay, Chester, Kerry A., Baker, James R., Smith, Mark E. B., Caddick, Stephen

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Next generation maleimides enable the controlled assembly of antibody–drug conjugates via native disulfide bond bridging Autor Schumacher, Felix F., Nunes, João P. M., Maruani, Antoine, Chudasama, Vijay, Smith, Mark E. B., Chester, Kerry A., Baker, James R., Caddick, Stephen

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