Resultados da pesquisa - C. Thomas Appleton

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  1. 1
    Osteoarthritis year in review 2017: biology

    Osteoarthritis year in review 2017: biology Por C. Thomas Appleton

    Publicado em 2017
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  2. 2
    Rho/ROCK and MEK/ERK activation by transforming growth factor-α induces articular cartilage degradation

    Rho/ROCK and MEK/ERK activation by transforming growth factor-α induces articular cartilage degradation Por C. Thomas Appleton, S.E. Usmani, John S. Mort, Frank Beier

    Publicado em 2009
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  3. 3
    Microarray Analyses of Gene Expression during Chondrocyte Differentiation Identifies Novel Regulators of Hypertrophy

    Microarray Analyses of Gene Expression during Chondrocyte Differentiation Identifies Novel Regulators of Hypertrophy Por Claudine G. James, C. Thomas Appleton, Veronica Ulici, T. Michael Underhill, Frank Beier

    Publicado em 2005
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  4. 4
    Reduction in Disease Progression by Inhibition of Transforming Growth Factor α–CCL2 Signaling in Experimental Posttraumatic Osteoarthritis

    Reduction in Disease Progression by Inhibition of Transforming Growth Factor α–CCL2 Signaling in Experimental Posttraumatic Osteoarthritis Por C. Thomas Appleton, S.E. Usmani, M.A. Pest, Vasek Pitelka, John S. Mort, Frank Beier

    Publicado em 2015
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  5. 5
    Study of subchondral bone adaptations in a rodent surgical model of OA using in vivo micro-computed tomography

    Study of subchondral bone adaptations in a rodent surgical model of OA using in vivo micro-computed tomography Por David D. McErlain, C. Thomas Appleton, Robert Litchfield, Vasek Pitelka, J.L. Henry, Suzanne M. Bernier, Frank Beier, David W. Holdsworth

    Publicado em 2007
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  6. 6
    Forced mobilization accelerates pathogenesis: characterization of a preclinical surgical model of osteoarthritis

    Forced mobilization accelerates pathogenesis: characterization of a preclinical surgical model of osteoarthritis Por C. Thomas Appleton, David D. McErlain, Vasek Pitelka, Neil Schwartz, Suzanne M. Bernier, James L. Henry, David W. Holdsworth, Frank Beier

    Publicado em 2007
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  7. 7
    F‐spondin, a neuroregulatory protein, is up‐regulated in osteoarthritis and regulates cartilage metabolism <i>via</i> TGF‐β activation

    F‐spondin, a neuroregulatory protein, is up‐regulated in osteoarthritis and regulates cartilage metabolism <i>via</i> TGF‐β activation Por Mukundan Attur, Glyn D. Palmer, H. Al-Mussawir, Mandar Dave, Cristina C. Teixeira, Daniel B. Rifkin, C. Thomas Appleton, Frank Beier, Steven B. Abramson

    Publicado em 2008
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  8. 8
    ADAMTS-7 forms a positive feedback loop with TNF-α in the pathogenesis of osteoarthritis

    ADAMTS-7 forms a positive feedback loop with TNF-α in the pathogenesis of osteoarthritis Por Yongjie Lai, Xiaohui Bai, Yunpeng Zhao, Qingyun Tian, Ben Liu, Edward Lin, Yuqing Chen, Brendan Lee, C. Thomas Appleton, Frank Beier, Xiuping Yu, Liu C

    Publicado em 2013
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  9. 9
    Brentuximab vedotin for skin involvement in refractory diffuse cutaneous systemic sclerosis, an open-label trial

    Brentuximab vedotin for skin involvement in refractory diffuse cutaneous systemic sclerosis, an open-label trial Por Andreu Fernández‐Codina, Tatiana Nevskaya, Murray Baron, C. Thomas Appleton, Matthew J. Cecchini, Amanda Philip, Maha El-Shimy, Louise Vanderhoek, Iago Pinal‐Fernandez, Janet Pope

    Publicado em 2024
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  10. 10
    Targeting STAT6-mediated synovial macrophage activation improves pain in experimental knee osteoarthritis

    Targeting STAT6-mediated synovial macrophage activation improves pain in experimental knee osteoarthritis Por Garth Blackler, Yue Lai-Zhao, Joseph Klapak, Holly T. Philpott, Kyle K. Pitchers, Andrew R. Maher, Benoit Fiset, Logan A. Walsh, Elizabeth R. Gillies, C. Thomas Appleton

    Publicado em 2024
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  11. 11
    Impact of aging on pulmonary cellular responses during mechanical ventilation

    Impact of aging on pulmonary cellular responses during mechanical ventilation Por A. Manji, Lefeng Wang, Cynthia Pape, Lynda A. McCaig, Alexandra Troitskaya, Onon Batnyam, Laura McDonald, C. Thomas Appleton, Ruud A. W. Veldhuizen, Sean E. Gill

    Publicado em 2025
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  12. 12
    A scoping review of how early-stage knee osteoarthritis has been defined

    A scoping review of how early-stage knee osteoarthritis has been defined Por Jean W. Liew, Lauren King, Armaghan Mahmoudian, Qiuke Wang, Hayden F. Atkinson, David Flynn, C. Thomas Appleton, Martin Englund, I.K. Haugen, Stefan Lohmander, J. Runhaar, Tuhina Neogi, Gillian Hawker

    Publicado em 2023
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  13. 13
    Three decades of advancements in osteoarthritis research: insights from transcriptomic, proteomic, and metabolomic studies

    Three decades of advancements in osteoarthritis research: insights from transcriptomic, proteomic, and metabolomic studies Por Muhammad Farooq, Kelsey H. Collins, Annemarie Lang, Tristan Maerz, Jeroen Geurts, Cristina Ruíz‐Romero, Ronald K. June, Y.F. Ramos, Sarah J. Rice, Shabana Amanda Ali, Chiara Pastrello, Igor Jurišica, C. Thomas Appleton, Jason S. Rockel, Mohit Kapoor

    Publicado em 2023
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  14. 14
    Sequencing identifies a distinct signature of circulating microRNAs in early radiographic knee osteoarthritis

    Sequencing identifies a distinct signature of circulating microRNAs in early radiographic knee osteoarthritis Por Shabana Amanda Ali, Rajiv Gandhi, Pratibha Potla, Sareh Keshavarzi, Osvaldo Espin‐Garcia, Konstantin Shestopaloff, Chiara Pastrello, Dylan Bethune-Waddell, Starlee Lively, Anthony V. Perruccio, Y. Raja Rampersaud, Christian Veillette, J.S. Rockel, Igor Jurišica, C. Thomas Appleton, Mohit Kapoor

    Publicado em 2020
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