Ngā hua rapu - C. David Weaver

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  1. 1
    A Thallium-Sensitive, Fluorescence-Based Assay for Detecting and Characterizing Potassium Channel Modulators in Mammalian Cells

    A Thallium-Sensitive, Fluorescence-Based Assay for Detecting and Characterizing Potassium Channel Modulators in Mammalian Cells mā C. David Weaver, David Harden, Steven I. Dworetzky, Barbara Robertson, Ronald J. Knox

    I whakaputaina 2004
    Whiwhi kuputuhi katoa
    Artigo
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  2. 2
    Small-molecule screen identifies inhibitors of the neuronal K-Cl cotransporter KCC2

    Small-molecule screen identifies inhibitors of the neuronal K-Cl cotransporter KCC2 mā Eric Delpire, Emily Days, L. Michelle Lewis, Dehui Mi, Kwang‐Ho Kim, Craig W. Lindsley, C. David Weaver

    I whakaputaina 2009
    Whiwhi kuputuhi katoa Whiwhi kuputuhi katoa
    Artigo
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  3. 3
    Inhibitors of 7-Dehydrocholesterol Reductase: Screening of a Collection of Pharmacologically Active Compounds in Neuro2a Cells

    Inhibitors of 7-Dehydrocholesterol Reductase: Screening of a Collection of Pharmacologically Active Compounds in Neuro2a Cells mā Hye‐Young Kim, Z̆eljka Korade, Keri A. Tallman, Wei Liu, C. David Weaver, Károly Mirnics, Ned A. Porter

    I whakaputaina 2016
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    Artigo
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  4. 4
    Optical control of neuronal activity using a light-operated GIRK channel opener (LOGO)

    Optical control of neuronal activity using a light-operated GIRK channel opener (LOGO) mā David M. Barber, Matthias Schönberger, Jessica Burgstaller, Joshua Levitz, C. David Weaver, Ehud Y. Isacoff, Herwig Baier, Dirk Trauner

    I whakaputaina 2015
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    Artigo
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  5. 5
    Synthesis and Evaluation of a Series of Heterobiarylamides That Are Centrally Penetrant Metabotropic Glutamate Receptor 4 (mGluR4) Positive Allosteric Modulators (PAMs)

    Synthesis and Evaluation of a Series of Heterobiarylamides That Are Centrally Penetrant Metabotropic Glutamate Receptor 4 (mGluR4) Positive Allosteric Modulators (PAMs) mā Darren W. Engers, Colleen M. Niswender, C. David Weaver, Satyawan Jadhav, Usha N. Menon, Rocio Zamorano, P. Jeffrey Conn, Craig W. Lindsley, Corey R. Hopkins

    I whakaputaina 2009
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    Artigo
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  6. 6
    Further optimization of the K-Cl cotransporter KCC2 antagonist ML077: Development of a highly selective and more potent in vitro probe

    Further optimization of the K-Cl cotransporter KCC2 antagonist ML077: Development of a highly selective and more potent in vitro probe mā Eric Delpire, Aleksandra Baranczak, Alex G. Waterson, Kwang‐Ho Kim, Nathan R. Kett, Ryan D. Morrison, J. Scott Daniels, C. David Weaver, Craig W. Lindsley

    I whakaputaina 2012
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    Artigo
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  7. 7
    Context-Dependent Pharmacology Exhibited by Negative Allosteric Modulators of Metabotropic Glutamate Receptor 7

    Context-Dependent Pharmacology Exhibited by Negative Allosteric Modulators of Metabotropic Glutamate Receptor 7 mā Colleen M. Niswender, Kari A. Johnson, Nicole Miller, Jennifer Ayala, Qingwei Luo, Richard D. Williams, Samir Saleh, Darren Orton, C. David Weaver, P. Jeffrey Conn

    I whakaputaina 2009
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    Artigo
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  8. 8
    High-Throughput Screening Reveals a Small-Molecule Inhibitor of the Renal Outer Medullary Potassium Channel and Kir7.1

    High-Throughput Screening Reveals a Small-Molecule Inhibitor of the Renal Outer Medullary Potassium Channel and Kir7.1 mā L. Michelle Lewis, Gautam Bhave, Brian A. Chauder, Sreedatta Banerjee, Katharina A. Lornsen, Rey Redha, Katherine Fallen, Craig W. Lindsley, C. David Weaver, Jerod S. Denton

    I whakaputaina 2009
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    Artigo
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  9. 9
    Mechanisms underlying the activation of G-protein–gated inwardly rectifying K<sup>+</sup>(GIRK) channels by the novel anxiolytic drug, ML297

    Mechanisms underlying the activation of G-protein–gated inwardly rectifying K<sup>+</sup>(GIRK) channels by the novel anxiolytic drug, ML297 mā Nicole Wydeven, Ezequiel Marrón Fernández de Velasco, Yu Du, Michael A. Benneyworth, Matthew C. Hearing, Rachel A. Fischer, Mark J. Thomas, C. David Weaver, Kevin Wickman

    I whakaputaina 2014
    Whiwhi kuputuhi katoa Whiwhi kuputuhi katoa
    Artigo
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  10. 10
    Discovery of the First Highly M5-Preferring Muscarinic Acetylcholine Receptor Ligand, an M5 Positive Allosteric Modulator Derived from a Series of 5-Trifluoromethoxy <i>N</i>-Benzyl Isatins

    Discovery of the First Highly M5-Preferring Muscarinic Acetylcholine Receptor Ligand, an M5 Positive Allosteric Modulator Derived from a Series of 5-Trifluoromethoxy <i>N</i>-Benzy... mā Thomas M. Bridges, Joy E. Marlo, Colleen M. Niswender, Carrie K. Jones, Satyawan Jadhav, Patrick R. Gentry, Hyekyung C. Plumley, C. David Weaver, P. Jeffrey Conn, Craig W. Lindsley

    I whakaputaina 2009
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    Artigo
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  11. 11
    Development of a Selective Small-Molecule Inhibitor of Kir1.1, the Renal Outer Medullary Potassium Channel

    Development of a Selective Small-Molecule Inhibitor of Kir1.1, the Renal Outer Medullary Potassium Channel mā Gautam Bhave, Brian A. Chauder, Wen Liu, Eric S. Dawson, Rishin J. Kadakia, Thuy Thi Thanh Nguyen, L. Michelle Lewis, Jens Meiler, C. David Weaver, Lisa M. Satlin, Craig W. Lindsley, Jerod S. Denton

    I whakaputaina 2010
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    Artigo
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  12. 12
    Discovery and Characterization of a Potent and Selective Inhibitor of Aedes aegypti Inward Rectifier Potassium Channels

    Discovery and Characterization of a Potent and Selective Inhibitor of Aedes aegypti Inward Rectifier Potassium Channels mā Rene Raphemot, Matthew F. Rouhier, Daniel R. Swale, Emily Days, C. David Weaver, Kimberly M. Lovell, Leah C. Konkel, Darren W. Engers, Sean F. Bollinger, Corey R. Hopkins, Peter M. Piermarini, Jerod S. Denton

    I whakaputaina 2014
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    Artigo
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  13. 13
    GIRK Channels Modulate Opioid-Induced Motor Activity in a Cell Type- and Subunit-Dependent Manner

    GIRK Channels Modulate Opioid-Induced Motor Activity in a Cell Type- and Subunit-Dependent Manner mā Lydia Kotecki, Matthew C. Hearing, Nora M. McCall, Ezequiel Marrón Fernández de Velasco, Marco Pravetoni, Devinder Arora, Nicole C. Victoria, Michaelanne B. Munoz, Zhilian Xia, Paul A. Slesinger, C. David Weaver, Kevin Wickman

    I whakaputaina 2015
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    Artigo
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  14. 14
    Discovery and optimization of a novel, selective and brain penetrant M1 positive allosteric modulator (PAM): The development of ML169, an MLPCN probe

    Discovery and optimization of a novel, selective and brain penetrant M1 positive allosteric modulator (PAM): The development of ML169, an MLPCN probe mā Paul R. Reid, Thomas M. Bridges, Douglas J. Sheffler, Hyekyung P. Cho, L. Michelle Lewis, Emily Days, J. Scott Daniels, Carrie K. Jones, Colleen M. Niswender, C. David Weaver, P. Jeffrey Conn, Craig W. Lindsley, Michael R. Wood

    I whakaputaina 2010
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    Artigo
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  15. 15
    Discovery and Characterization of Novel Subtype-Selective Allosteric Agonists for the Investigation of M<sub>1</sub> Receptor Function in the Central Nervous System

    Discovery and Characterization of Novel Subtype-Selective Allosteric Agonists for the Investigation of M<sub>1</sub> Receptor Function in the Central Nervous System mā Evan P. Lebois, Thomas M. Bridges, L. Michelle Lewis, Eric S. Dawson, Alexander S. Kane, Zixiu Xiang, Satyawan Jadhav, Huiyong Yin, J. Phillip Kennedy, Jens Meiler, Colleen M. Niswender, Carrie K. Jones, P. Jeffrey Conn, C. David Weaver, Craig W. Lindsley

    I whakaputaina 2009
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    Artigo
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  16. 16
    ML297 (VU0456810), the First Potent and Selective Activator of the GIRK Potassium Channel, Displays Antiepileptic Properties in Mice

    ML297 (VU0456810), the First Potent and Selective Activator of the GIRK Potassium Channel, Displays Antiepileptic Properties in Mice mā Kristian Kaufmann, Ian M. Romaine, Emily Days, Conrado Pascual, A. Malik, Liya Yang, Bende Zou, Yu Du, Greg Sliwoski, Ryan D. Morrison, Jerod S. Denton, Colleen M. Niswender, J. Scott Daniels, Gary A. Sulikowski, Xinmin Xie, Craig W. Lindsley, C. David Weaver

    I whakaputaina 2013
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    Artigo
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  17. 17
    Discovery, Characterization, and Effects on Renal Fluid and Electrolyte Excretion of the Kir4.1 Potassium Channel Pore Blocker, VU0134992

    Discovery, Characterization, and Effects on Renal Fluid and Electrolyte Excretion of the Kir4.1 Potassium Channel Pore Blocker, VU0134992 mā Sujay V. Kharade, H. Kurata, Aaron M. Bender, Anna L. Blobaum, Eric E. Figueroa, Amanda M. Duran, Meghan Kramer, Emily Days, Paige N. Vinson, Daniel Flores, Lisa M. Satlin, Jens Meiler, C. David Weaver, Craig W. Lindsley, Corey R. Hopkins, Jerod S. Denton

    I whakaputaina 2018
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    Artigo
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  18. 18
    Identification of ML204, a Novel Potent Antagonist That Selectively Modulates Native TRPC4/C5 Ion Channels

    Identification of ML204, a Novel Potent Antagonist That Selectively Modulates Native TRPC4/C5 Ion Channels mā Melissa Miller, Jie Shi, Yingmin Zhu, Maksym Kustov, Jinbin Tian, Amy O. Stevens, Meng Wu, Jia Xu, Shunyou Long, Yang Pu, Alexander V. Zholos, James M. Salovich, C. David Weaver, Corey R. Hopkins, Craig W. Lindsley, Owen B. McManus, Min Li, Michael X. Zhu

    I whakaputaina 2011
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    Artigo
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  19. 19
    Functional Impact of Allosteric Agonist Activity of Selective Positive Allosteric Modulators of Metabotropic Glutamate Receptor Subtype 5 in Regulating Central Nervous System Function

    Functional Impact of Allosteric Agonist Activity of Selective Positive Allosteric Modulators of Metabotropic Glutamate Receptor Subtype 5 in Regulating Central Nervous System Funct... mā Meredith J. Noetzel, Jerri M. Rook, Paige N. Vinson, Hyekyung P. Cho, Emily Days, Ying Zhou, Alice L. Rodriguez, Hilde Lavreysen, Shaun R. Stauffer, Colleen M. Niswender, Zixiu Xiang, J. Scott Daniels, Carrie K. Jones, Craig W. Lindsley, C. David Weaver, P. Jeffrey Conn

    I whakaputaina 2011
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    Artigo
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  20. 20
    Discovery, Characterization, and Antiparkinsonian Effect of Novel Positive Allosteric Modulators of Metabotropic Glutamate Receptor 4

    Discovery, Characterization, and Antiparkinsonian Effect of Novel Positive Allosteric Modulators of Metabotropic Glutamate Receptor 4 mā Colleen M. Niswender, Kari A. Johnson, C. David Weaver, Carrie K. Jones, Zixiu Xiang, Qingwei Luo, Alice L. Rodriguez, Joy E. Marlo, Tomas de Paulis, Analisa D. Thompson, Emily Days, Tasha Nalywajko, Cheryl A. Austin, Michael Baxter Williams, Jennifer Ayala, Richard D. Williams, Craig W. Lindsley, P. Jeffrey Conn

    I whakaputaina 2008
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    Artigo
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