検索結果 - C. David Weaver
-
1
-
2
-
3
-
4
-
5
Synthesis and Evaluation of a Series of Heterobiarylamides That Are Centrally Penetrant Metabotropic Glutamate Receptor 4 (mGluR4) Positive Allosteric Modulators (PAMs) 著者: Darren W. Engers, Colleen M. Niswender, C. David Weaver, Satyawan Jadhav, Usha N. Menon, Rocio Zamorano, P. Jeffrey Conn, Craig W. Lindsley, Corey R. Hopkins
出版事項 2009Artigo -
6
Further optimization of the K-Cl cotransporter KCC2 antagonist ML077: Development of a highly selective and more potent in vitro probe 著者: Eric Delpire, Aleksandra Baranczak, Alex G. Waterson, Kwang‐Ho Kim, Nathan R. Kett, Ryan D. Morrison, J. Scott Daniels, C. David Weaver, Craig W. Lindsley
出版事項 2012Artigo -
7
Context-Dependent Pharmacology Exhibited by Negative Allosteric Modulators of Metabotropic Glutamate Receptor 7 著者: Colleen M. Niswender, Kari A. Johnson, Nicole Miller, Jennifer Ayala, Qingwei Luo, Richard D. Williams, Samir Saleh, Darren Orton, C. David Weaver, P. Jeffrey Conn
出版事項 2009Artigo -
8
High-Throughput Screening Reveals a Small-Molecule Inhibitor of the Renal Outer Medullary Potassium Channel and Kir7.1 著者: L. Michelle Lewis, Gautam Bhave, Brian A. Chauder, Sreedatta Banerjee, Katharina A. Lornsen, Rey Redha, Katherine Fallen, Craig W. Lindsley, C. David Weaver, Jerod S. Denton
出版事項 2009Artigo -
9
Mechanisms underlying the activation of G-protein–gated inwardly rectifying K<sup>+</sup>(GIRK) channels by the novel anxiolytic drug, ML297 著者: Nicole Wydeven, Ezequiel Marrón Fernández de Velasco, Yu Du, Michael A. Benneyworth, Matthew C. Hearing, Rachel A. Fischer, Mark J. Thomas, C. David Weaver, Kevin Wickman
出版事項 2014Artigo -
10
Discovery of the First Highly M5-Preferring Muscarinic Acetylcholine Receptor Ligand, an M5 Positive Allosteric Modulator Derived from a Series of 5-Trifluoromethoxy <i>N</i>-Benzy... 著者: Thomas M. Bridges, Joy E. Marlo, Colleen M. Niswender, Carrie K. Jones, Satyawan Jadhav, Patrick R. Gentry, Hyekyung C. Plumley, C. David Weaver, P. Jeffrey Conn, Craig W. Lindsley
出版事項 2009Artigo -
11
Development of a Selective Small-Molecule Inhibitor of Kir1.1, the Renal Outer Medullary Potassium Channel 著者: Gautam Bhave, Brian A. Chauder, Wen Liu, Eric S. Dawson, Rishin J. Kadakia, Thuy Thi Thanh Nguyen, L. Michelle Lewis, Jens Meiler, C. David Weaver, Lisa M. Satlin, Craig W. Lindsley, Jerod S. Denton
出版事項 2010Artigo -
12
Discovery and Characterization of a Potent and Selective Inhibitor of Aedes aegypti Inward Rectifier Potassium Channels 著者: Rene Raphemot, Matthew F. Rouhier, Daniel R. Swale, Emily Days, C. David Weaver, Kimberly M. Lovell, Leah C. Konkel, Darren W. Engers, Sean F. Bollinger, Corey R. Hopkins, Peter M. Piermarini, Jerod S. Denton
出版事項 2014Artigo -
13
GIRK Channels Modulate Opioid-Induced Motor Activity in a Cell Type- and Subunit-Dependent Manner 著者: Lydia Kotecki, Matthew C. Hearing, Nora M. McCall, Ezequiel Marrón Fernández de Velasco, Marco Pravetoni, Devinder Arora, Nicole C. Victoria, Michaelanne B. Munoz, Zhilian Xia, Paul A. Slesinger, C. David Weaver, Kevin Wickman
出版事項 2015Artigo -
14
Discovery and optimization of a novel, selective and brain penetrant M1 positive allosteric modulator (PAM): The development of ML169, an MLPCN probe 著者: Paul R. Reid, Thomas M. Bridges, Douglas J. Sheffler, Hyekyung P. Cho, L. Michelle Lewis, Emily Days, J. Scott Daniels, Carrie K. Jones, Colleen M. Niswender, C. David Weaver, P. Jeffrey Conn, Craig W. Lindsley, Michael R. Wood
出版事項 2010Artigo -
15
Discovery and Characterization of Novel Subtype-Selective Allosteric Agonists for the Investigation of M<sub>1</sub> Receptor Function in the Central Nervous System 著者: Evan P. Lebois, Thomas M. Bridges, L. Michelle Lewis, Eric S. Dawson, Alexander S. Kane, Zixiu Xiang, Satyawan Jadhav, Huiyong Yin, J. Phillip Kennedy, Jens Meiler, Colleen M. Niswender, Carrie K. Jones, P. Jeffrey Conn, C. David Weaver, Craig W. Lindsley
出版事項 2009Artigo -
16
ML297 (VU0456810), the First Potent and Selective Activator of the GIRK Potassium Channel, Displays Antiepileptic Properties in Mice 著者: Kristian Kaufmann, Ian M. Romaine, Emily Days, Conrado Pascual, A. Malik, Liya Yang, Bende Zou, Yu Du, Greg Sliwoski, Ryan D. Morrison, Jerod S. Denton, Colleen M. Niswender, J. Scott Daniels, Gary A. Sulikowski, Xinmin Xie, Craig W. Lindsley, C. David Weaver
出版事項 2013Artigo -
17
Discovery, Characterization, and Effects on Renal Fluid and Electrolyte Excretion of the Kir4.1 Potassium Channel Pore Blocker, VU0134992 著者: Sujay V. Kharade, H. Kurata, Aaron M. Bender, Anna L. Blobaum, Eric E. Figueroa, Amanda M. Duran, Meghan Kramer, Emily Days, Paige N. Vinson, Daniel Flores, Lisa M. Satlin, Jens Meiler, C. David Weaver, Craig W. Lindsley, Corey R. Hopkins, Jerod S. Denton
出版事項 2018Artigo -
18
Identification of ML204, a Novel Potent Antagonist That Selectively Modulates Native TRPC4/C5 Ion Channels 著者: Melissa Miller, Jie Shi, Yingmin Zhu, Maksym Kustov, Jinbin Tian, Amy O. Stevens, Meng Wu, Jia Xu, Shunyou Long, Yang Pu, Alexander V. Zholos, James M. Salovich, C. David Weaver, Corey R. Hopkins, Craig W. Lindsley, Owen B. McManus, Min Li, Michael X. Zhu
出版事項 2011Artigo -
19
Functional Impact of Allosteric Agonist Activity of Selective Positive Allosteric Modulators of Metabotropic Glutamate Receptor Subtype 5 in Regulating Central Nervous System Funct... 著者: Meredith J. Noetzel, Jerri M. Rook, Paige N. Vinson, Hyekyung P. Cho, Emily Days, Ying Zhou, Alice L. Rodriguez, Hilde Lavreysen, Shaun R. Stauffer, Colleen M. Niswender, Zixiu Xiang, J. Scott Daniels, Carrie K. Jones, Craig W. Lindsley, C. David Weaver, P. Jeffrey Conn
出版事項 2011Artigo -
20
Discovery, Characterization, and Antiparkinsonian Effect of Novel Positive Allosteric Modulators of Metabotropic Glutamate Receptor 4 著者: Colleen M. Niswender, Kari A. Johnson, C. David Weaver, Carrie K. Jones, Zixiu Xiang, Qingwei Luo, Alice L. Rodriguez, Joy E. Marlo, Tomas de Paulis, Analisa D. Thompson, Emily Days, Tasha Nalywajko, Cheryl A. Austin, Michael Baxter Williams, Jennifer Ayala, Richard D. Williams, Craig W. Lindsley, P. Jeffrey Conn
出版事項 2008Artigo
関連主題
Chemistry
Biology
Biochemistry
Receptor
Pharmacology
Medicine
Neuroscience
Allosteric regulation
Allosteric modulator
Biophysics
Glutamate receptor
Metabotropic glutamate receptor
Organic chemistry
Potassium channel
In vitro
Metabotropic glutamate receptor 5
Metabotropic receptor
Agonist
Cell biology
Endocrinology
Gene
Internal medicine
Metabotropic glutamate receptor 2
Stereochemistry
G protein
G protein-coupled inwardly-rectifying potassium channel
Ion channel
Metabotropic glutamate receptor 1
Metabotropic glutamate receptor 7
Anxiolytic