检索结果 - Brinton Seashore‐Ludlow
- Showing 1 - 16 results of 16
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Cancer-associated fibroblasts rewire the estrogen receptor response in luminal breast cancer, enabling estrogen independence 由 Steven Reid, Jessica Pantaleo, Paulina Bolívar, Matteo Bocci, Jonas Sjölund, Mikkel Morsing, Eugenia Cordero, Sara Larsson, Maria Malmberg, Brinton Seashore‐Ludlow, Kristian Pietras
出版 2024Artigo -
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Systematic profiling of cancer‐fibroblast interactions reveals drug combinations in ovarian cancer 由 Greta Gudoitytė, O. P. Sharma, Laura Leuenberger, Emelie Wallin, Josefin Fernebro, Päivi Östling, Rebecka Bergström, Johan Lindberg, Ulrika Joneborg, Olli Kallioniemi, Brinton Seashore‐Ludlow
出版 2025Artigo -
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FGFR4 phosphorylates MST1 to confer breast cancer cells resistance to MST1/2-dependent apoptosis 由 S. Pauliina Turunen, Pernilla von Nandelstadh, Tiina Öhman, Erika Gucciardo, Brinton Seashore‐Ludlow, Beatriz Martins, Ville Rantanen, Huini Li, Katrin Höpfner, Päivi Östling, Markku Varjosalo, Kaisa Lehti
出版 2019Artigo -
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High-content morphological profiling by Cell Painting in 3D spheroids. 由 Christa Ringers, David Holmberg, Åsmund Flobak, Polina Georgieva, Malin Jarvius, Martin M. Johansson, Anders Larsson, Dan Rosén, Brinton Seashore‐Ludlow, Torkild Visnes, Jordi Carreras‐Puigvert, Ola Spjuth
出版 2025Pré-impressão -
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Predicting Cancer-Specific Vulnerability via Data-Driven Detection of Synthetic Lethality 由 Livnat Jerby‐Arnon, Nadja Pfetzer, Yedael Y. Waldman, Lynn McGarry, Daniel James, Emma Shanks, Brinton Seashore‐Ludlow, Adam Weinstock, Tamar Geiger, Paul A. Clemons, Eyal Gottlieb, Eytan Ruppin
出版 2014Artigo -
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Inhibitors of the Cysteine Synthase CysM with Antibacterial Potency against Dormant <i>Mycobacterium tuberculosis</i> 由 Katharina Brunner, Selma Maric, Rudraraju Srilakshmi Reshma, Helena Almqvist, Brinton Seashore‐Ludlow, Anna‐Lena Gustavsson, Ömer Poyraz, Perumal Yogeeswari, Thomas Lundbäck, Michaela Vallin, Dharmarajan Sriram, R. Schnell, G. Schneider
出版 2016Artigo -
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Targeted inhibition of WIP1 and histone H3K27 demethylase activity synergistically suppresses neuroblastoma growth 由 Diana Treis, Kristina Lundberg, Nicola Bell, Panagiotis Alkinoos Polychronopoulos, Conny Tümmler, Emma Åkerlund, Stefania Aliverti, Ingrid Lilienthal, Adena Pepich, Brinton Seashore‐Ludlow, Kazuyasu Sakaguchi, Per Kogner, John Inge Johnsen, Malin Wickström
出版 2025Artigo -
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Targeting <scp>CDK</scp> 2 overcomes melanoma resistance against <scp>BRAF</scp> and Hsp90 inhibitors 由 Alireza Azimi, Stefano Caramuta, Brinton Seashore‐Ludlow, Johan Boström, Jonathan L. Robinson, Fredrik Edfors, Rainer Tuominen, Kristel Kemper, Oscar Krijgsman, Daniel S. Peeper, Jens Nielsen, Johan Hansson, Suzanne Egyházi Brage, Mikael Altun, Mathias Uhlén, Gianluca Maddalo
出版 2018Artigo -
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Small-molecule studies identify CDK8 as a regulator of IL-10 in myeloid cells 由 Liv Johannessen, Thomas B. Sundberg, Daniel J. O’Connell, Raivo Kolde, James Berstler, Katelyn Billings, Bernard Khor, Brinton Seashore‐Ludlow, Anne Fassl, Caitlin Russell, Isabel Latorre, Baishan Jiang, Daniel B. Graham, José R. Perez, Piotr Siciński, Andrew J. Phillips, Stuart L. Schreiber, Nathanael S. Gray, Alykhan F. Shamji, Ramnik J. Xavier
出版 2017Artigo -
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DiSCoVERing Innovative Therapies for Rare Tumors: Combining Genetically Accurate Disease Models with<i>In Silico</i>Analysis to Identify Novel Therapeutic Targets 由 Allison R. Hanaford, Tenley C. Archer, Antoinette Price, Ulf D. Kahlert, Jarek Maciaczyk, Guido Nikkhah, Jong Wook Kim, Tobias Ehrenberger, Paul A. Clemons, Vlado Dančík, Brinton Seashore‐Ludlow, Vasanthi S. Viswanathan, Michelle L. Stewart, Matthew G. Rees, Alykhan Shamji, Stuart L. Schreiber, Ernest Fraenkel, Scott L. Pomeroy, Jill P. Mesirov, Pablo Tamayo, Charles G. Eberhart, Eric H. Raabe
出版 2016Artigo -
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Harnessing Connectivity in a Large-Scale Small-Molecule Sensitivity Dataset 由 Brinton Seashore‐Ludlow, Matthew G. Rees, Jaime H. Cheah, Murat Cokol, Edmund V. Price, Matthew E. Coletti, Victor Jones, Nicole E. Bodycombe, Christian K. Soule, Joshua Gould, Benjamin Alexander, Ava Li, Philip Montgomery, Mathias J. Wawer, Nurdan Kuru, Joanne Kotz, C. Suk-Yee Hon, Benito Muñoz, Ted Liefeld, Vlado Dančík, Joshua A. Bittker, Michelle Palmer, James E. Bradner, Alykhan F. Shamji, Paul A. Clemons, Stuart L. Schreiber
出版 2015Artigo -
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Correlating chemical sensitivity and basal gene expression reveals mechanism of action 由 Matthew G. Rees, Brinton Seashore‐Ludlow, Jaime H. Cheah, Drew Adams, Edmund V. Price, Shubhroz Gill, Sarah Javaid, Matthew E. Coletti, Victor Jones, Nicole E. Bodycombe, Christian K. Soule, Benjamin Alexander, Ava Li, Philip Montgomery, Joanne Kotz, C. Suk-Yee Hon, Benito Muñoz, Ted Liefeld, Vlado Dančík, Daniel A. Haber, Clary B. Clish, Joshua A. Bittker, Michelle Palmer, Bridget K. Wagner, Paul A. Clemons, Alykhan F. Shamji, Stuart L. Schreiber
出版 2015Artigo -
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Dependency of a therapy-resistant state of cancer cells on a lipid peroxidase pathway 由 Vasanthi S. Viswanathan, Matthew J. Ryan, Harshil Dhruv, Shubhroz Gill, Ossia M. Eichhoff, Brinton Seashore‐Ludlow, Samuel D. Kaffenberger, John K. Eaton, Kaoru Shimada, Andrew J. Aguirre, Srinivas R. Viswanathan, Shrikanta Chattopadhyay, Pablo Tamayo, Wan Seok Yang, Matthew G. Rees, Sixun Chen, Žarko Bošković, Sarah Javaid, Cherrie Huang, Xiaoyun Wu, Yuen-Yi Tseng, Elisabeth Roider, Dong Gao, James M. Cleary, Brian M. Wolpin, Jill P. Mesirov, Daniel A. Haber, Jeffrey A. Engelman, Jesse S. Boehm, Joanne Kotz, Cindy Hon, Yu Chen, William C. Hahn, Mitchell P. Levesque, John G. Doench, Michael E. Berens, Alykhan F. Shamji, Paul A. Clemons, Brent R. Stockwell, Stuart L. Schreiber
出版 2017Artigo -
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Validation and development of MTH1 inhibitors for treatment of cancer 由 Ulrika Warpman Berglund, Kumar Sanjiv, Helge Gad, Christina Kalderén, Tobias Koolmeister, Therese Pham, Camilla Göktürk, Rozbeh Jafari, Gianluca Maddalo, Brinton Seashore‐Ludlow, Alexey Chernobrovkin, Aleksandr Manoilov, Ioannis S. Pateras, Azita Rasti, Ann‐Sofie Jemth, Ingrid Almlöf, Olga Loseva, Torkild Visnes, Berglind O. Einarsdottir, Fabienne Z. Gaugaz, Amyza Saleh, Björn Platzack, Olov Wallner, Karl S. A. Vallin, Martin Henriksson, Prasad B. Wakchaure, Sanjay R. Borhade, Patrick Herr, Yvonne Kallberg, Paweł Baranczewski, Evert Homan, Elisée Wiita, Varun Nagpal, Thomas Meijer, Nicolaas Schipper, Sean G. Rudd, Lars Bräutigam, Annika Lindqvist, Anne M. Filppula, Te‐Chang Lee, Per Artursson, Jonas A. Nilsson, Vassilis G. Gorgoulis, Janne Lehtiö, Roman A. Zubarev, Martin Scobie, Thomas Helleday
出版 2016Artigo
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Biology
Cancer
Genetics
Biochemistry
Cancer research
Chemistry
Computational biology
Gene
In vitro
Medicine
Apoptosis
Cell
Cell biology
Internal medicine
Breast cancer
Cancer cell
Cell cycle
Computer science
Cyclin-dependent kinase
Enzyme
Cell culture
Drug resistance
Endocrinology
Kinase
Molecular biology
Pathology
Pharmacology
Phosphorylation
Programmed cell death
Tumor cells