Search Results - Brian P. Danysh

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  1. 1
    The lens capsule

    The lens capsule by Brian P. Danysh, Melinda K. Duncan

    Published 2008
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  2. 2
    BRAF Inhibitors: Experience in Thyroid Cancer and General Review of Toxicity

    BRAF Inhibitors: Experience in Thyroid Cancer and General Review of Toxicity by Maria E. Cabanillas, Ami Patel, Brian P. Danysh, Ramona Dadu, Scott Kopetz, Gerald S. Falchook

    Published 2014
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  3. 3
    Abnormal Expression of Collagen IV in Lens Activates Unfolded Protein Response Resulting in Cataract

    Abnormal Expression of Collagen IV in Lens Activates Unfolded Protein Response Resulting in Cataract by Zeynep Fırtına Karagonlar, Brian P. Danysh, Xiaoyang Bai, Douglas B. Gould, Takehiro Kobayashi, Melinda K. Duncan

    Published 2009
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  4. 4
    Long-term vemurafenib treatment drives inhibitor resistance through a spontaneous KRAS G12D mutation in a BRAF V600E papillary thyroid carcinoma model

    Long-term vemurafenib treatment drives inhibitor resistance through a spontaneous KRAS G12D mutation in a BRAF V600E papillary thyroid carcinoma model by Brian P. Danysh, Erin Rieger, Deepankar Sinha, Caitlin Evers, Gilbert J. Cote, Maria E. Cabanillas, Marie‐Claude Hofmann

    Published 2016
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  5. 5
    Src-mediated regulation of the PI3K pathway in advanced papillary and anaplastic thyroid cancer

    Src-mediated regulation of the PI3K pathway in advanced papillary and anaplastic thyroid cancer by Thomas C. Beadnell, Kelsey W. Nassar, Madison M. Rose, Erin G. Clark, Brian P. Danysh, Marie‐Claude Hofmann, Nikita Pozdeyev, Rebecca E. Schweppe

    Published 2018
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  6. 6
    The Transcription Factor ETV5 Mediates BRAFV600E-Induced Proliferation and TWIST1 Expression in Papillary Thyroid Cancer Cells

    The Transcription Factor ETV5 Mediates BRAFV600E-Induced Proliferation and TWIST1 Expression in Papillary Thyroid Cancer Cells by Oorvashi Roy Puli, Brian P. Danysh, Elena McBeath, Deepankar Sinha, Nguyet M. Hoang, Reid T. Powell, Heather E. Danysh, Maria E. Cabanillas, Gilbert J. Cote, Marie‐Claude Hofmann

    Published 2018
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  7. 7
    Understanding Resistance Mechanisms and Growth Kinetics of CLL Treated with Covalent and Non-Covalent BTK Inhibitors

    Understanding Resistance Mechanisms and Growth Kinetics of CLL Treated with Covalent and Non-Covalent BTK Inhibitors by Aishath Naeem, Liang Li, Filippo Utro, Justin Cha, Junko Tsuji, Stacey M. Fernandes, Roberta Santos Azevedo, Francesca Morelli, Zunqiu Wang, Samantha J. Shupe, Kahn Rhrissorrakrai, Chaya Levovitz, Brian P. Danysh, Alexandria Kluge, Matthew S. Davids, Ignaty Leshchiner, Laxmi Parida, Gad Getz, Jennifer R. Brown

    Published 2023
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  8. 8
    Parallel Genomic Alterations of Antigen and Payload Targets Mediate Polyclonal Acquired Clinical Resistance to Sacituzumab Govitecan in Triple-Negative Breast Cancer

    Parallel Genomic Alterations of Antigen and Payload Targets Mediate Polyclonal Acquired Clinical Resistance to Sacituzumab Govitecan in Triple-Negative Breast Cancer by James T. Coates, Sheng Sun, Ignaty Leshchiner, Nayana Thimmiah, Elizabeth E. Martin, Daniel E. McLoughlin, Brian P. Danysh, Kara Slowik, Raquel A. Jacobs, Kahn Rhrissorrakrai, Filippo Utro, Chaya Levovitz, Elyssa N. Denault, Charlotte S. Walmsley, Avinash Kambadakone, James R. Stone, Steven J. Isakoff, Laxmi Parida, Dejan Juric, Gad Getz, Aditya Bardia, Leif W. Ellisen

    Published 2021
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  9. 9
    Pirtobrutinib targets BTK C481S in ibrutinib-resistant CLL but second-site BTK mutations lead to resistance

    Pirtobrutinib targets BTK C481S in ibrutinib-resistant CLL but second-site BTK mutations lead to resistance by Aishath Naeem, Filippo Utro, Qing Wang, Justin Cha, Mauno Vihinen, Stephen P. Martindale, Yinglu Zhou, Yue Ren, Svitlana Tyekucheva, Annette S. Kim, Stacey M. Fernandes, Gordon Saksena, Kahn Rhrissorrakrai, Chaya Levovitz, Brian P. Danysh, Kara Slowik, Raquel A. Jacobs, Matthew S. Davids, James A. Lederer, Rula Zain, Smith Rjh, Ignaty Leshchiner, Laxmi Parida, Gad Getz, Jennifer R. Brown

    Published 2022
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  10. 10
    Developmental mosaicism underlying EGFR-mutant lung cancer presenting with multiple primary tumors

    Developmental mosaicism underlying EGFR-mutant lung cancer presenting with multiple primary tumors by Risa Burr, Ignaty Leshchiner, Christina L. Costantino, Martin Blohmer, Tilak Sundaresan, Justin Cha, Karsen Seeger, Sara Y. Guay, Brian P. Danysh, Ira Gore, Raquel A. Jacobs, Kara Slowik, Filippo Utro, Kahn Rhrissorrakrai, Chaya Levovitz, Jaimie L. Barth, Taronish D. Dubash, Brian Chirn, Laxmi Parida, Lecia V. Sequist, Jochen K. Lennerz, Mari Mino‐Kenudson, Shyamala Maheswaran, Kamila Naxerova, Gad Getz, Daniel A. Haber

    Published 2024
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  11. 11
    Distinct cellular dynamics associated with response to CAR-T therapy for refractory B cell lymphoma

    Distinct cellular dynamics associated with response to CAR-T therapy for refractory B cell lymphoma by Nicholas J. Haradhvala, Mark B. Leick, Katie Maurer, Satyen H. Gohil, Rebecca C. Larson, Ning Yao, Kathleen Gallagher, Katelin Katsis, Matthew J. Frigault, Jackson Southard, Shuqiang Li, Michael C. Kann, Harrison Silva, Max Jan, Kahn Rhrissorrakrai, Filippo Utro, Chaya Levovitz, Raquel A. Jacobs, Kara Slowik, Brian P. Danysh, Kenneth J. Livak, Laxmi Parida, Judith A. Ferry, Caron A. Jacobson, Catherine J. Wu, Gad Getz, Marcela V. Maus

    Published 2022
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  12. 12
    Genetic events associated with venetoclax resistance in CLL identified by whole-exome sequencing of patient samples

    Genetic events associated with venetoclax resistance in CLL identified by whole-exome sequencing of patient samples by Jasneet Kaur Khalsa, Justin Cha, Filippo Utro, Aishath Naeem, Ishwarya Murali, Yanan Kuang, Kevin Vasquez, Liang Li, Svitlana Tyekucheva, Stacey M. Fernandes, Lauren Véronèse, Romain Guièze, Binu K. Sasi, Zixu Wang, John‐Hanson Machado, Harrison Bai, Maryam Alasfour, Kahn Rhrissorrakrai, Chaya Levovitz, Brian P. Danysh, Kara Slowik, Raquel A. Jacobs, Matthew S. Davids, Cloud P. Paweletz, Ignaty Leshchiner, Laxmi Parida, Gad Getz, Jennifer R. Brown

    Published 2023
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  13. 13
    Allosteric PI3Kα Inhibition Overcomes On-target Resistance to Orthosteric Inhibitors Mediated by Secondary <i>PIK3CA</i> Mutations

    Allosteric PI3Kα Inhibition Overcomes On-target Resistance to Orthosteric Inhibitors Mediated by Secondary <i>PIK3CA</i> Mutations by Andreas Varkaris, Ferran Fece de la Cruz, Elizabeth E. Martin, Bryanna L. Norden, Nicholas Chevalier, Allison M. Kehlmann, Ignaty Leshchiner, Haley Barnes, Sara Ehnstrom, Anastasia-Maria Stavridi, Xin Yuan, Janice S. Kim, Haley Ellis, Alkistis Papatheodoridi, Hakan Günaydin, Brian P. Danysh, Laxmi Parida, Ioannis Sanidas, Yongli Ji, Kayao Lau, Gerburg M. Wulf, Aditya Bardia, Laura M. Spring, Steven J. Isakoff, Jochen K. Lennerz, Kathryn Del Vecchio, Levi Pierce, Ermira Pazolli, Gad Getz, Ryan B. Corcoran, Dejan Juric

    Published 2023
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  14. 14
    AXL and Error-Prone DNA Replication Confer Drug Resistance and Offer Strategies to Treat EGFR-Mutant Lung Cancer

    AXL and Error-Prone DNA Replication Confer Drug Resistance and Offer Strategies to Treat EGFR-Mutant Lung Cancer by Ashish Noronha, Nishanth Belugali Nataraj, Joo Sang Lee, Benny Zhitomirsky, Yaara Oren, Sara Oster, Moshit Lindzen, Saptaparna Mukherjee, Rainer Will, Soma Ghosh, Arturo Simoni‐Nieves, Aakanksha Verma, Rishita Chatterjee, Simone Borgoni, Welles Robinson, Sanju Sinha, Alexander Brandis, D. Lucas Kerr, Wei Wu, Arunachalam Sekar, Suvendu Giri, Youngmin Chung, Diana Drago-García, Brian P. Danysh, Mattia Lauriola, Michelangelo Fiorentino, Andrea Ardizzoni, Moshe Oren, Collin M. Blakely, Jideofor Ezike, Stefan Wiemann, Laxmi Parida, Trever G. Bivona, Rami I. Aqeilan, Joan S. Brugge, Aviv Regev, Gad Getz, Eytan Ruppin, Yosef Yarden

    Published 2022
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  15. 15
    Liquid versus tissue biopsy for detecting acquired resistance and tumor heterogeneity in gastrointestinal cancers

    Liquid versus tissue biopsy for detecting acquired resistance and tumor heterogeneity in gastrointestinal cancers by Aparna R. Parikh, Ignaty Leshchiner, Liudmila Elagina, Lipika Goyal, Chaya Levovitz, Giulia Siravegna, Dimitri Livitz, Kahn Rhrissorrakrai, Elizabeth E. Martin, Emily E. Van Seventer, Megan Hanna, Kara Slowik, Filippo Utro, Christopher J. Pinto, Alicia Wong, Brian P. Danysh, Ferran Fece de la Cruz, Isobel J. Fetter, Brandon Nadres, Heather A. Shahzade, Jill N. Allen, Lawrence S. Blaszkowsky, Jeffrey W. Clark, Bruce J. Giantonio, Janet E. Murphy, Ryan David Nipp, Eric Roeland, David P. Ryan, Colin D. Weekes, Eunice L. Kwak, Jason E. Faris, Jennifer Y. Wo, François Aguet, Ipsita Dey‐Guha, Mehlika Hazar-Rethinam, Dora Dias‐Santagata, David T. Ting, Andrew X. Zhu, Theodore S. Hong, Todd R. Golub, A. John Iafrate, Viktor A. Adalsteinsson, Alberto Bardelli, Laxmi Parida, Dejan Juric, Gad Getz, Ryan B. Corcoran

    Published 2019
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  16. 16
    Evolutionary history of transformation from chronic lymphocytic leukemia to Richter syndrome

    Evolutionary history of transformation from chronic lymphocytic leukemia to Richter syndrome by Erin M. Parry, Ignaty Leshchiner, Romain Guièze, Connor Johnson, Eugen Tausch, Sameer A. Parikh, Camilla K. Lemvigh, Julien Broséus, Sébastien Hergalant, Conor Messer, Filippo Utro, Chaya Levovitz, Kahn Rhrissorrakrai, Liang Li, Daniel Rosebrock, Shanye Yin, Stephanie Deng, Kara Slowik, Raquel A. Jacobs, Teddy Huang, Shuqiang Li, Geoff Fell, Robert Redd, Ziao Lin, Binyamin A. Knisbacher, Dimitri Livitz, Christof Schneider, Neil Ruthen, Liudmila Elagina, Amaro Taylor‐Weiner, Bria Persaud, Aina Zurita Martinez, Stacey M. Fernandes, Noelia Purroy, Annabelle Anandappa, Jialin Ma, Julian M. Hess, Laura Z. Rassenti, Thomas J. Kipps, Nitin Jain, William G. Wierda, Florence Cymbalista, Pierre Feugier, Neil E. Kay, Kenneth J. Livak, Brian P. Danysh, Chip Stewart, Donna Neuberg, Matthew S. Davids, Jennifer R. Brown, Laxmi Parida, Stephan Stilgenbauer, Gad Getz, Catherine J. Wu

    Published 2023
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  17. 17
    A Model for Decoding Resistance in Precision Oncology: Acquired Resistance to FGFR inhibitors in Cholangiocarcinoma

    A Model for Decoding Resistance in Precision Oncology: Acquired Resistance to FGFR inhibitors in Cholangiocarcinoma by Love Goyal, Daniel DiToro, Francesco Facchinetti, E Martin, P. Peng, Islam Baiev, Ramakrishnan Iyer, Jochen Maurer, Sylvia A. Reyes, Karen Zhang, Umair Majeed, J.E. Berchuck, C.T. Chen, Charlotte S. Walmsley, C Pinto, D. Vasseur, John D. Gordan, Kabir Mody, Mitesh J. Borad, Thomas B. Karasic, N. Damjanov, Brian P. Danysh, E. Wehrenberg-Klee, Avinash Kambadakone, Sudipta Saha, Isaac Hoffman, Kari Nelson, S. Iyer, Qiang Xiao, Caixia Sun, H. Wang, Liang Li, M. M. Javle, Bo Lin, William Proctor Harris, Andrew X. Zhu, James M. Cleary, Keith T. Flaherty, Tim Harris, Rachna T. Shroff, Ignaty Leshchiner, Laxmi Parida, Robin Kate Kelley, Jean Fan, James R. Stone, Nataliya V. Uboha, Hiroshi Hirai, Hiroshi Sootome, Frank Wu, D.C. Bensen, Antoine Hollebecque, Luc Friboulet, Jochen K. Lennerz, Gaddy Getz, Dejan Juric

    Published 2024
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