Kết quả tìm kiếm - Brian Dougherty

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  1. 1
    Molecular characterization of hasB from an operon required for hyaluronic acid synthesis in group A streptococci. Demonstration of UDP-glucose dehydrogenase activity.

    Molecular characterization of hasB from an operon required for hyaluronic acid synthesis in group A streptococci. Demonstration of UDP-glucose dehydrogenase activity. Bằng Brian Dougherty, I van de Rijn

    Được phát hành 1993
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    Artigo
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  2. 2
    Molecular Characterization of hasC from an Operon Required for Hyaluronic Acid Synthesis in Group A Streptococci DEMONSTRATION OF UDP-GLUCOSE PYROPHOSPHORYLASE ACTIVITY

    Molecular Characterization of hasC from an Operon Required for Hyaluronic Acid Synthesis in Group A Streptococci DEMONSTRATION OF UDP-GLUCOSE PYROPHOSPHORYLASE ACTIVITY Bằng Dinene L. Crater, Brian Dougherty, I van de Rijn

    Được phát hành 1995
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    Artigo
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  3. 3
    Orthogonal Comparison of Four Plasma NGS Tests With Tumor Suggests Technical Factors are a Major Source of Assay Discordance

    Orthogonal Comparison of Four Plasma NGS Tests With Tumor Suggests Technical Factors are a Major Source of Assay Discordance Bằng Daniel Stetson, Ambar Ahmed, Xing Xu, Barrett Nuttall, Tristan Lubinski, Justin Johnson, J. Carl Barrett, Brian Dougherty

    Được phát hành 2019
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    Artigo
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  4. 4
    Genetic Organization of Transposase Regions Surrounding <i>bla</i> <sub>KPC</sub> Carbapenemase Genes on Plasmids from <i>Klebsiella</i> Strains Isolated in a New York City Hospital

    Genetic Organization of Transposase Regions Surrounding <i>bla</i> <sub>KPC</sub> Carbapenemase Genes on Plasmids from <i>Klebsiella</i> Strains Isolated in a New York City Hospita... Bằng Thomas D. Gootz, Mary Kay Lescoe, Fadia B. Dib-Hajj, Brian Dougherty, Wen He, Phyllis Della‐Latta, Richard C. Huard

    Được phát hành 2009
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    Artigo
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  5. 5
    VarDict: a novel and versatile variant caller for next-generation sequencing in cancer research

    VarDict: a novel and versatile variant caller for next-generation sequencing in cancer research Bằng Zhongwu Lai, Aleksandra Markovets, Miika Ahdesmäki, Brad Chapman, Oliver Hofmann, Robert McEwen, Justin Johnson, Brian Dougherty, J. Carl Barrett, Jonathan R. Dry

    Được phát hành 2016
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    Artigo
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  6. 6
    Biological and clinical evidence for somatic mutations in <i>BRCA1</i> and <i>BRCA2</i> as predictive markers for olaparib response in high-grade serous ovarian cancers in the maintenance setting

    Biological and clinical evidence for somatic mutations in <i>BRCA1</i> and <i>BRCA2</i> as predictive markers for olaparib response in high-grade serous ovarian cancers in the main... Bằng Brian Dougherty, Zhongwu Lai, Darren Hodgson, Maria Orr, Matthew Hawryluk, James Sun, Roman Yelensky, Stuart Spencer, Jane Robertson, Tony W. Ho, Anitra Fielding, Jonathan A. Ledermann, J. Carl Barrett

    Được phát hành 2017
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    Artigo
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  7. 7
    Prioritisation of Structural Variant Calls in Cancer Genomes

    Prioritisation of Structural Variant Calls in Cancer Genomes Bằng Miika Ahdesmäki, Brad Chapman, Pablo E. Cingolani, Oliver Hofmann, Aleksandr Sidoruk, Zhongwu Lai, Г. А. Захаров, Mikhail Rodichenko, Mikhail Alperovich, David F. Jenkins, T. Hedley Carr, Daniel Stetson, Brian Dougherty, J. Carl Barrett, Justin Johnson

    Được phát hành 2016
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  8. 8
    Acquired EGFR C797S mutation mediates resistance to AZD9291 in non–small cell lung cancer harboring EGFR T790M

    Acquired EGFR C797S mutation mediates resistance to AZD9291 in non–small cell lung cancer harboring EGFR T790M Bằng Kenneth S. Thress, Cloud P. Paweletz, Enriqueta Felip, Byoung Chul Cho, Daniel Stetson, Brian Dougherty, Zhongwu Lai, Aleksandra Markovets, Ana Vivancos, Yanan Kuang, Dalia Ercan, Sarah E Matthews, Mireille Cantarini, J. Carl Barrett, Pasi A. Jänne, Geoffrey R. Oxnard

    Được phát hành 2015
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    Artigo
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  9. 9
    Impact of KRAS codon subtypes from a randomised phase II trial of selumetinib plus docetaxel in KRAS mutant advanced non-small-cell lung cancer

    Impact of KRAS codon subtypes from a randomised phase II trial of selumetinib plus docetaxel in KRAS mutant advanced non-small-cell lung cancer Bằng Pasi A. Jänne, Ian C. P. Smith, Gael McWalter, Helen Mann, Brian Dougherty, Jill Walker, Maria Orr, Darren Hodgson, Alice T. Shaw, José Rodrigues Pereira, G. Jeannin, Johan Vansteenkiste, C.H. Barrios, Fábio Franke, Lucio Crinò, Paul D. Smith

    Được phát hành 2015
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    Artigo
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  10. 10
    Candidate biomarkers of PARP inhibitor sensitivity in ovarian cancer beyond the BRCA genes

    Candidate biomarkers of PARP inhibitor sensitivity in ovarian cancer beyond the BRCA genes Bằng Darren Hodgson, Brian Dougherty, Zhongwu Lai, Anitra Fielding, Lynda Grinsted, Stuart Spencer, Mark J. O’Connor, Tony W. Ho, Jane Robertson, Jerry S. Lanchbury, Kirsten M. Timms, Alexander Gutin, Maria Orr, Helen Jones, C. Blake Gilks, Chris Womack, Charlie Gourley, Jonathan A. Ledermann, J. Carl Barrett

    Được phát hành 2018
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    Artigo
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  11. 11
    Multiomic Characterization of High-Grade Serous Ovarian Carcinoma Enables High-Resolution Patient Stratification

    Multiomic Characterization of High-Grade Serous Ovarian Carcinoma Enables High-Resolution Patient Stratification Bằng Robert L. Hollis, Alison Meynert, Caroline O. Michie, Tzyvia Rye, Michael Churchman, Amelia Hallas-Potts, Ian Croy, W. Glenn McCluggage, Alistair Williams, Clare Bartos, Yasushi Iida, Aikou Okamoto, Brian Dougherty, J. Carl Barrett, Ruth March, Athena Matakidou, Patricia Roxburgh, Colin A. Semple, D. Paul Harkin, Richard D. Kennedy, C. Simon Herrington, Charlie Gourley

    Được phát hành 2022
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  12. 12
    Distinct mechanisms govern populations of myeloid-derived suppressor cells in chronic viral infection and cancer

    Distinct mechanisms govern populations of myeloid-derived suppressor cells in chronic viral infection and cancer Bằng Evgenii N. Tcyganov, Shino Hanabuchi, Ayumi Hashimoto, David G. Campbell, Gozde Kar, Timothy Slidel, Corinne Cayatte, Aimee Landry, Fernanda Pilataxi, Susana Hayes, Brian Dougherty, Kristin C. Hicks, Kathy Mulgrew, Chih-Hang Anthony Tang, Chih‐Chi Andrew Hu, Wei-Feng Guo, Sergei I. Grivennikov, Mohammed-Alkhatim A. Ali, Jean‐Christophe Beltra, E. John Wherry, Yulia Nefedova, Dmitry I. Gabrilovich

    Được phát hành 2021
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    Artigo
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  13. 13
    Genes Contributing to Pain Sensitivity in the Normal Population: An Exome Sequencing Study

    Genes Contributing to Pain Sensitivity in the Normal Population: An Exome Sequencing Study Bằng Frances M. K. Williams, Serena Scollen, Dandan Cao, Yasin Memari, Craig Hyde, Baohong Zhang, Ben S. Sidders, Daniel Ziemek, Yujian Shi, Juliette Harris, Ian Harrow, Brian Dougherty, Anders Mälarstig, Robert McEwen, Joel C. Stephens, Ketan Patel, Cristina Menni, So-Youn Shin, Dylan Hodgkiss, Gabriela Surdulescu, Wen He, Xin Jin, Stephen B. McMahon, Nicole Soranzo, Sally John, Jun Wang, Tim D. Spector

    Được phát hành 2012
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    Artigo
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  14. 14
    Acquired Resistance to the Mutant-Selective EGFR Inhibitor AZD9291 Is Associated with Increased Dependence on RAS Signaling in Preclinical Models

    Acquired Resistance to the Mutant-Selective EGFR Inhibitor AZD9291 Is Associated with Increased Dependence on RAS Signaling in Preclinical Models Bằng Catherine A. Eberlein, Daniel Stetson, Aleksandra Markovets, Katherine Al-Kadhimi, Zhongwu Lai, Paul R. Fisher, Catherine B. Meador, Paula J. Spitzler, Eiki Ichihara, Sarah J. Ross, Miika Ahdesmäki, Ambar Ahmed, Laura E. Ratcliffe, Elizabeth L. Christey O'Brien, Claire H. Barnes, H. Shelton Brown, Paul D. Smith, Jonathan R. Dry, Garry Beran, Kenneth S. Thress, Brian Dougherty, William Pao, Darren A.E. Cross

    Được phát hành 2015
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    Artigo
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  15. 15
    Long-Term Responders on Olaparib Maintenance in High-Grade Serous Ovarian Cancer: Clinical and Molecular Characterization

    Long-Term Responders on Olaparib Maintenance in High-Grade Serous Ovarian Cancer: Clinical and Molecular Characterization Bằng Stéphanie Lheureux, Zhongwu Lai, Brian Dougherty, Sarah Runswick, Darren Hodgson, Kirsten M. Timms, Jerry S. Lanchbury, Stan Kaye, Charlie Gourley, David D.L. Bowtell, Elise C. Kohn, Clare L. Scott, Ursula A. Matulonis, Tony Panzarella, Katherine Karakasis, Julia V. Burnier, C. Blake Gilks, Mark J. O’Connor, Jane Robertson, Jonathan A. Ledermann, J. Carl Barrett, Tony W. Ho, Amit M. Oza

    Được phát hành 2017
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    Artigo
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  16. 16
    Capivasertib Plus Paclitaxel Versus Placebo Plus Paclitaxel As First-Line Therapy for Metastatic Triple-Negative Breast Cancer: The PAKT Trial

    Capivasertib Plus Paclitaxel Versus Placebo Plus Paclitaxel As First-Line Therapy for Metastatic Triple-Negative Breast Cancer: The PAKT Trial Bằng Peter Schmid, Jacinta Abraham, Stephen Chan, Duncan Wheatley, Adrian Murray Brunt, Gia Nemsadze, Richard D. Baird, Winnie Yeo, Peter Hall, Timothy Perren, Robert C. Stein, László Mangel, Jean-­Marc Ferrero, Melissa Phillips, John Conibear, Javier Cortés, Andrew Foxley, Elza C. de Bruin, Robert McEwen, Daniel Stetson, Brian Dougherty, Shah‐Jalal Sarker, Aaron Prendergast, Max McLaughlin-Callan, Matthew Burgess, Cheryl Lawrence, Hayley Cartwright, Kelly Mousa, Nicholas C. Turner

    Được phát hành 2019
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    Artigo
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  17. 17
    Structural Variants at the<i>BRCA1/2</i>Loci are a Common Source of Homologous Repair Deficiency in High-grade Serous Ovarian Carcinoma

    Structural Variants at the<i>BRCA1/2</i>Loci are a Common Source of Homologous Repair Deficiency in High-grade Serous Ovarian Carcinoma Bằng Ailith Ewing, Alison Meynert, Michael Churchman, Graeme R. Grimes, Robert L. Hollis, C. Simon Herrington, Tzyvia Rye, Clare Bartos, Ian Croy, Michelle Ferguson, Mairi Lennie, Trevor McGoldrick, Neil McPhail, Nadeem Siddiqui, Suzanne Dowson, Rosalind Glasspool, Melanie Mackean, Fiona Nussey, Brian McDade, Darren Ennis, Lynn McMahon, Athena Matakidou, Brian Dougherty, Ruth March, J. Carl Barrett, Iain A. McNeish, Andrew V. Biankin, Patricia Roxburgh, Charlie Gourley, Colin A. Semple

    Được phát hành 2021
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    Artigo
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  18. 18
    Characterising the contribution of rare protein-coding germline variants to prostate cancer risk and severity in 37,184 cases

    Characterising the contribution of rare protein-coding germline variants to prostate cancer risk and severity in 37,184 cases Bằng Jonathan Mitchell, Niedzica Camacho, Patrick R. Shea, Konrad H. Stopsack, Joseph Vijai, Oliver S. Burren, Ryan S. Dhindsa, Abhishek Nag, Jacob E. Berchuck, Amanda O’Neill, Ali Abbasi, Anthony W. Zoghbi, Jesús Alegre-Díaz, Pablo Kuri‐Morales, Jaime Berúmen, Roberto Tapia‐Conyer, Jonathan Emberson, Jason Torres, Rory Collins, Quanli Wang, David B. Goldstein, Athena Matakidou, Carolina Haefliger, Lauren Anderson-Dring, Ruth March, Vaidehi Jobanputra, Brian Dougherty, Keren Carss, Slavé Petrovski, Philip W. Kantoff, Kenneth Offit, Lorelei A. Mucci, Mark M. Pomerantz, Margarete A. Fabre

    Được phát hành 2024
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  19. 19
    Assessing the contribution of rare protein-coding germline variants to prostate cancer risk and severity in 37,184 cases

    Assessing the contribution of rare protein-coding germline variants to prostate cancer risk and severity in 37,184 cases Bằng Jonathan Mitchell, Niedzica Camacho, Patrick R. Shea, Konrad H. Stopsack, Joseph Vijai, Oliver S. Burren, Ryan S. Dhindsa, Abhishek Nag, Jacob E. Berchuck, Amanda O’Neill, Ali Abbasi, Anthony W. Zoghbi, Jesús Alegre-Díaz, Pablo Kuri‐Morales, Jaime Berúmen, Roberto Tapia‐Conyer, Jonathan Emberson, Jason Torres, Rory Collins, Quanli Wang, David B. Goldstein, Athena Matakidou, Carolina Haefliger, Lauren Anderson-Dring, Ruth March, Vaidehi Jobanputra, Brian Dougherty, Keren Carss, Slavé Petrovski, Philip W. Kantoff, Kenneth Offit, Lorelei A. Mucci, Mark M. Pomerantz, Margarete A. Fabre

    Được phát hành 2025
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    Revisão
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  20. 20
    AKT Inhibition in Solid Tumors With <i>AKT1</i> Mutations

    AKT Inhibition in Solid Tumors With <i>AKT1</i> Mutations Bằng David M. Hyman, Lillian M. Smyth, Mark T.A. Donoghue, Shannon N. Westin, Philippe L. Bédard, Emma Dean, Hideaki Bando, Anthony B. El-Khoueiry, José Alejandro Pérez Fidalgo, Alain C. Mita, Jan H.M. Schellens, Matthew T. Chang, Jonathan Reichel, Nancy Bouvier, S. Duygu Selçuklu, Tara E. Soumerai, Jean Torrisi, Joseph P. Erinjeri, Helen Ambrose, J. Carl Barrett, Brian Dougherty, Andrew Foxley, Justin P.O. Lindemann, Robert McEwen, Martin Pass, Gaia Schiavon, Michael F. Berger, Sarat Chandarlapaty, David B. Solit, Udai Banerji, José Baselga, Barry S. Taylor

    Được phát hành 2017
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    Artigo
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