Resultats de la cerca - Brian D. Marsden

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  1. 1
    The Humoral Immune Response to HCV: Understanding is Key to Vaccine Development

    The Humoral Immune Response to HCV: Understanding is Key to Vaccine Development per Siobhán B. Cashman, Brian D. Marsden, Lynn B. Dustin

    Publicat 2014
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  2. 2
    ChromoHub: a data hub for navigators of chromatin-mediated signalling

    ChromoHub: a data hub for navigators of chromatin-mediated signalling per Lihua Liu, Xi Ting Zhen, Emily Denton, Brian D. Marsden, Matthieu Schapira

    Publicat 2012
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  3. 3
    UbiHub: a data hub for the explorers of ubiquitination pathways

    UbiHub: a data hub for the explorers of ubiquitination pathways per Lihua Liu, David Damerell, Leonidas Koukouflis, Yufeng Tong, Brian D. Marsden, Matthieu Schapira

    Publicat 2018
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  4. 4
    Linking genotypes database with locus-specific database and genotype–phenotype correlation in phenylketonuria

    Linking genotypes database with locus-specific database and genotype–phenotype correlation in phenylketonuria per Sarah Wettstein, Jarl Underhaug, Belén Pérez, Brian D. Marsden, Wyatt W. Yue, Aurora Martı́nez, Nenad Blau

    Publicat 2014
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  5. 5
    A systematic interaction map of validated kinase inhibitors with Ser/Thr kinases

    A systematic interaction map of validated kinase inhibitors with Ser/Thr kinases per O. Fedorov, Brian D. Marsden, Vanda Pogačić, P. Rellos, Susanne Müller, Alex N. Bullock, Juerg Schwaller, M. Sundström, Stefan Knapp

    Publicat 2007
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  6. 6
    Decreased blood vessel density and endothelial cell subset dynamics during ageing of the endocrine system

    Decreased blood vessel density and endothelial cell subset dynamics during ageing of the endocrine system per Junyu Chen, Luciana Lippo, Rossella Labella, Sin Lih Tan, Brian D. Marsden, Michael L. Dustin, Saravana K. Ramasamy, Anjali P. Kusumbe

    Publicat 2020
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  7. 7
    Mapping tenascin-C interaction with toll-like receptor 4 reveals a new subset of endogenous inflammatory triggers

    Mapping tenascin-C interaction with toll-like receptor 4 reveals a new subset of endogenous inflammatory triggers per Lorena Zuliani‐Alvarez, Anna M. Marzeda, Claire Deligne, Anja Schwenzer, Fiona E. McCann, Brian D. Marsden, Anna M. Piccinini, Kim S. Midwood

    Publicat 2017
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  8. 8
    3,5-Dimethylisoxazoles Act As Acetyl-lysine-mimetic Bromodomain Ligands

    3,5-Dimethylisoxazoles Act As Acetyl-lysine-mimetic Bromodomain Ligands per David S. Hewings, Minghua Wang, Martin Philpott, O. Fedorov, Sagar Uttarkar, P. Filippakopoulos, S. Picaud, Chaitanya Vuppusetty, Brian D. Marsden, Stefan Knapp, Stuart J. Conway, Tom D. Heightman

    Publicat 2011
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  9. 9
    The treatment of Wilms' tumour: results of the United Kingdom Children's Cancer Study Group (UKCCSG) second Wilms' tumour study

    The treatment of Wilms' tumour: results of the United Kingdom Children's Cancer Study Group (UKCCSG) second Wilms' tumour study per Christopher Mitchell, P. Morris Jones, Anna Kelsey, Gordan Vujanić, Brian D. Marsden, R S Shannon, P. Gornall, Cátherine M. Owens, Roger Taylor, John Imeson, Hayden T. Middleton, Jon Pritchard

    Publicat 2000
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  10. 10
    A poised fragment library enables rapid synthetic expansion yielding the first reported inhibitors of PHIP(2), an atypical bromodomain

    A poised fragment library enables rapid synthetic expansion yielding the first reported inhibitors of PHIP(2), an atypical bromodomain per Oakley B. Cox, T. Krojer, P.M. Collins, Octovia Monteiro, R. Talon, A.R. Bradley, O. Fedorov, Jahangir Amin, Brian D. Marsden, John Spencer, F. von Delft, Paul E. Brennan

    Publicat 2015
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  11. 11
    [1,2,4]Triazolo[4,3-<i>a</i>]phthalazines: Inhibitors of Diverse Bromodomains

    [1,2,4]Triazolo[4,3-<i>a</i>]phthalazines: Inhibitors of Diverse Bromodomains per O. Fedorov, Hannah Lingard, Christopher Wells, Octovia Monteiro, S. Picaud, Tracy Keates, Clarence Yapp, Martin Philpott, Sarah Martin, I. Felletar, Brian D. Marsden, P. Filippakopoulos, Susanne Müller, Stefan Knapp, Paul E. Brennan

    Publicat 2013
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  12. 12
    Structural Basis for Cul3 Protein Assembly with the BTB-Kelch Family of E3 Ubiquitin Ligases

    Structural Basis for Cul3 Protein Assembly with the BTB-Kelch Family of E3 Ubiquitin Ligases per Peter Canning, C.D.O. Cooper, T. Krojer, James W. Murray, A.C.W. Pike, A. Chaikuad, Tracy Keates, Chancievan Thangaratnarajah, Viktorija Hojzan, Brian D. Marsden, O. Gileadi, Stefan Knapp, F. von Delft, Alex N. Bullock

    Publicat 2013
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  13. 13
    High-resolution 3D imaging uncovers organ-specific vascular control of tissue aging

    High-resolution 3D imaging uncovers organ-specific vascular control of tissue aging per Junyu Chen, Unnikrishnan Sivan, Sin Lih Tan, Luciana Lippo, Jessica De Angelis, Rossella Labella, Amit Singh, Alexandros Chatzis, Stanley Cheuk, Mino Medhghalchi, Jesús Gil, Georg A. Holländer, Brian D. Marsden, Richard Williams, Saravana K. Ramasamy, Anjali P. Kusumbe

    Publicat 2021
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  14. 14
    Identification of a Chemical Probe for Bromo and Extra C-Terminal Bromodomain Inhibition through Optimization of a Fragment-Derived Hit

    Identification of a Chemical Probe for Bromo and Extra C-Terminal Bromodomain Inhibition through Optimization of a Fragment-Derived Hit per Paul V. Fish, P. Filippakopoulos, Gerwyn Bish, Paul E. Brennan, Mark E. Bunnage, Andrew S. Cook, Oleg Federov, Brian S. Gerstenberger, Hannah M. Jones, Stefan Knapp, Brian D. Marsden, Karl Nocka, Dafydd R. Owen, Martin Philpott, S. Picaud, Michael J. Primiano, Michael J. Ralph, Nunzio Sciammetta, John D. Trzupek

    Publicat 2012
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  15. 15
    Structures of ABCB10, a human ATP-binding cassette transporter in apo- and nucleotide-bound states

    Structures of ABCB10, a human ATP-binding cassette transporter in apo- and nucleotide-bound states per C.A. Shintre, A.C.W. Pike, Qiuhong Li, Jung-In Kim, A. Barr, S. Goubin, Leela Shrestha, Jing Yang, G. Berridge, Jonathan E. Ross, Phillip J. Stansfeld, Mark S.P. Sansom, A.M. Edwards, C. Bountra, Brian D. Marsden, F. von Delft, Alex N. Bullock, O. Gileadi, N. Burgess-Brown, Elisabeth P. Carpenter

    Publicat 2013
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  16. 16
    Quantitative SARS-CoV-2 anti-spike responses to Pfizer–BioNTech and Oxford–AstraZeneca vaccines by previous infection status

    Quantitative SARS-CoV-2 anti-spike responses to Pfizer–BioNTech and Oxford–AstraZeneca vaccines by previous infection status per David W. Eyre, Sheila Lumley, Jia Wei, Stuart Cox, Tim James, Anita Justice, Gerald Jesuthasan, Denise O’Donnell, Alison Howarth, Stephanie B. Hatch, Brian D. Marsden, Emma Jones, David I. Stuart, Daniel Ebner, Sarah Hoosdally, Derrick W. Crook, Tim Peto, Timothy M. Walker, Nicole Stoesser, Philippa C. Matthews, Koen B. Pouwels, A. Sarah Walker, Katie Jeffery

    Publicat 2021
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  17. 17
    Persistence of SARS-CoV-2 antibodies over 18 months following infection: UK Biobank COVID-19 Serology Study

    Persistence of SARS-CoV-2 antibodies over 18 months following infection: UK Biobank COVID-19 Serology Study per Jelena Bešević, Ben Lacey, Howard Callen, Wemimo Omiyale, Megan Conroy, Qi Feng, Derrick W. Crook, Nicola Doherty, Daniel Ebner, David W. Eyre, D. Fry, Edward Horn, E. Yvonne Jones, Brian D. Marsden, Tünde Pető, Fenella Starkey, David I. Stuart, Samantha Welsh, N.C. Wood, A. P. Young, Allen Young, Mark Effingham, Rory Collins, Jo Holliday, Naomi E. Allen

    Publicat 2023
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  18. 18
    A data science roadmap for open science organizations engaged in early-stage drug discovery

    A data science roadmap for open science organizations engaged in early-stage drug discovery per Kristina Edfeldt, A.M. Edwards, Ola Engkvist, Judith Günther, Matthew Hartley, David G. Hulcoop, Andrew R. Leach, Brian D. Marsden, Amelie Menge, Leonie Misquitta, Susanne Müller, Dafydd R. Owen, Kristof T. Schütt, Nicholas J. Skelton, Andreas Steffen, Alexander Tropsha, Erik Vernet, Yanli Wang, James Wellnitz, Timothy M. Willson, Djork-Arné Clevert, Benjamin Haibe‐Kains, Lovisa Holmberg Schiavone, Matthieu Schapira

    Publicat 2024
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  19. 19
    A genetics-led approach defines the drug target landscape of 30 immune-related traits

    A genetics-led approach defines the drug target landscape of 30 immune-related traits per Hai Fang, Hans Wolf, Bogdan Knezevic, Katie L. Burnham, Julie Osgood, Anna Sanniti, Alicia Lledó Lara, Silva Kasela, Stéphane De Cesco, Jörg K. Wegner, Lahiru Handunnetthi, Fiona E. McCann, Liye Chen, Takuya Sekine, Paul E. Brennan, Brian D. Marsden, David Damerell, Christopher A. O’Callaghan, C. Bountra, Paul Bowness, Yvonne Sundström, Lili Milani, Louise Berg, Hinrich W. H. Göhlmann, Pieter J. Peeters, Benjamin P. Fairfax, M. Sundström, Julian C. Knight

    Publicat 2019
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  20. 20
    The duration, dynamics and determinants of SARS-CoV-2 antibody responses in individual healthcare workers

    The duration, dynamics and determinants of SARS-CoV-2 antibody responses in individual healthcare workers per Sheila Lumley, Jia Wei, Denise O’Donnell, Nicole Stoesser, Philippa C. Matthews, Alison Howarth, Stephanie B. Hatch, Brian D. Marsden, Stuart Cox, Tim James, Liam J Peck, Thomas Ritter, Zoe de Toledo, Richard J. Cornall, E Yvonne Jones, David I. Stuart, Gavin Screaton, Daniel Ebner, Sarah Hoosdally, Derrick W. Crook, Christopher P. Conlon, Koen B. Pouwels, A. Sarah Walker, Tim Peto, Timothy M. Walker, Katie Jeffery, David W. Eyre

    Publicat 2020
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