Výsledky vyhledávání - Brandon J. Aubrey

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  1. 1
    Tumor-Suppressor Functions of the TP53 Pathway

    Tumor-Suppressor Functions of the TP53 Pathway Autor Brandon J. Aubrey, Andreas Strasser, Gemma L. Kelly

    Vydáno 2016
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  2. 2
    How does p53 induce apoptosis and how does this relate to p53-mediated tumour suppression?

    How does p53 induce apoptosis and how does this relate to p53-mediated tumour suppression? Autor Brandon J. Aubrey, Gemma L. Kelly, Ana Janic, Marco J. Herold, Andreas Strasser

    Vydáno 2017
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  3. 3
    Loss of a Single Mcl-1 Allele Inhibits MYC-Driven Lymphomagenesis by Sensitizing Pro-B Cells to Apoptosis

    Loss of a Single Mcl-1 Allele Inhibits MYC-Driven Lymphomagenesis by Sensitizing Pro-B Cells to Apoptosis Autor Stephanie Grabow, Alex R. D. Delbridge, Brandon J. Aubrey, Cassandra J. Vandenberg, Andreas Strasser

    Vydáno 2016
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  4. 4
    An Inducible Lentiviral Guide RNA Platform Enables the Identification of Tumor-Essential Genes and Tumor-Promoting Mutations In Vivo

    An Inducible Lentiviral Guide RNA Platform Enables the Identification of Tumor-Essential Genes and Tumor-Promoting Mutations In Vivo Autor Brandon J. Aubrey, Gemma L. Kelly, Andrew J. Kueh, Margs S. Brennan, Liam O’Connor, Liz Milla, Stephen Wilcox, Lin Tai, Andreas Strasser, Marco J. Herold

    Vydáno 2015
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  5. 5
    Mutant TRP53 exerts a target gene-selective dominant-negative effect to drive tumor development

    Mutant TRP53 exerts a target gene-selective dominant-negative effect to drive tumor development Autor Brandon J. Aubrey, Ana Janic, Yunshun Chen, Catherine Chang, Elizabeth Lieschke, Sarah T. Diepstraten, Andrew J. Kueh, Jonathan P. Bernardini, Grant Dewson, Lorraine A. O’Reilly, Lachlan Whitehead, Anne K. Voss, Gordon K. Smyth, Andreas Strasser, Gemma L. Kelly

    Vydáno 2018
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  6. 6
    Targeting of MCL-1 kills MYC-driven mouse and human lymphomas even when they bear mutations in <i>p53</i>

    Targeting of MCL-1 kills MYC-driven mouse and human lymphomas even when they bear mutations in <i>p53</i> Autor Gemma L. Kelly, Stephanie Grabow, Stefan Glaser, Leah Fitzsimmons, Brandon J. Aubrey, Toru Okamoto, Liz J. Valente, Mikara Robati, Lin Tai, W. Douglas Fairlie, Erinna F. Lee, Mikael S. Lindström, Klas G. Wiman, David C.S. Huang, Philippe Bouillet, Martin Rowe, Alan B. Rickinson, Marco J. Herold, Andreas Strasser

    Vydáno 2014
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  7. 7
    IKAROS and MENIN coordinate therapeutically actionable leukemogenic gene expression in MLL-r acute myeloid leukemia

    IKAROS and MENIN coordinate therapeutically actionable leukemogenic gene expression in MLL-r acute myeloid leukemia Autor Brandon J. Aubrey, Jevon Cutler, Wallace Bourgeois, Katherine A. Donovan, Shengqing Gu, Charlie Hatton, Sarah C. Perlee, Florian Perner, Homa Rahnamoun, Alexandra C. P. Theall, Jill A. Henrich, Qian Zhu, Radosław P. Nowak, Young‐Joon Kim, Salma Parvin, Anjali Cremer, Sarah Naomi Olsen, Nicholas A. Eleuteri, Yana Pikman, Gerard M. McGeehan, Kimberly Stegmaier, Anthony Letai, Eric S. Fischer, X. Shirley Liu, Scott A. Armstrong

    Vydáno 2022
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  8. 8
    PHF6 regulates hematopoietic stem and progenitor cells and its loss synergizes with expression of TLX3 to cause leukemia

    PHF6 regulates hematopoietic stem and progenitor cells and its loss synergizes with expression of TLX3 to cause leukemia Autor Helen M. McRae, Alexandra L. Garnham, Yifang Hu, Matthew T. Witkowski, Mark Corbett, Mathew P. Dixon, Rose E. May, Bilal N. Sheikh, William Chiang, Andrew J. Kueh, Tan Nguyen, Kevin Man, Renee Gloury, Brandon J. Aubrey, Antonia N. Policheni, Ladina Di Rago, Warren S. Alexander, Daniel H.D. Gray, Andreas Strasser, Edwin D. Hawkins, Stephen Wilcox, Jozef Gécz, Axel Kallies, Matthew P. McCormack, Gordon K. Smyth, Anne K. Voss, Tim Thomas

    Vydáno 2019
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  9. 9
    Intact TP-53 function is essential for sustaining durable responses to BH3-mimetic drugs in leukemias

    Intact TP-53 function is essential for sustaining durable responses to BH3-mimetic drugs in leukemias Autor Rachel Thijssen, Sarah T. Diepstraten, Donia M. Moujalled, Edward Chew, Christoffer Flensburg, Melissa X. Shi, Michael A. Dengler, Véronique Litalien, Sarah MacRaild, Maoshan Chen, Natasha S. Anstee, Boris Reljić, Sarah S. Gabriel, Tirta M. Djajawi, Chris Riffkin, Brandon J. Aubrey, Catherine Chang, Lin Tai, Zhen Xu, Thomas Morley, Giovanna Pomilio, Claudia Bruedigam, Axel Kallies, David A. Stroud, Ashish Bajel, Ruth M. Kluck, Steven Lane, Marie Schoumacher, Sébastien Banquet, Ian J. Majewski, Andreas Strasser, Andrew W. Roberts, David C.S. Huang, Fiona C. Brown, Gemma L. Kelly, Andrew H. Wei

    Vydáno 2021
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  10. 10
    Inhibitors of histone acetyltransferases KAT6A/B induce senescence and arrest tumour growth

    Inhibitors of histone acetyltransferases KAT6A/B induce senescence and arrest tumour growth Autor Jonathan B. Baell, David J. Leaver, S.J. Hermans, Gemma L. Kelly, Margs S. Brennan, Natalie L. Downer, Nghi Nguyen, Johannes Wichmann, Helen M. McRae, Yuqing Yang, Ben Cleary, H. Rachel Lagiakos, Stephen Mieruszynski, Guido Pacini, Hannah Vanyai, Maria Bergamasco, Rose E. May, Bethany K. Davey, Kimberly J Morgan, A.J. Sealey, Beinan Wang, Natasha Zamudio, Stephen Wilcox, Alexandra L. Garnham, Bilal N. Sheikh, Brandon J. Aubrey, Karen Doggett, Matthew Chung, Melanie de Silva, John D. Bentley, Pat Pilling, Meghan Hattarki, Olan Dolezal, Matthew L. Dennis, Hendrik Falk, Bin Ren, Susan A. Charman, Karen L. White, Jai Rautela, Andrea Newbold, Edwin D. Hawkins, Ricky W. Johnstone, Nicholas D. Huntington, Thomas S. Peat, Joan K. Heath, Andreas Strasser, Michael W. Parker, Gordon K. Smyth, Ian P. Street, Brendon Monahan, Anne K. Voss, Tim Thomas

    Vydáno 2018
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