檢索結果 - Bradfield, Jonathan

Progress in Understanding Type 1 Diabetes Through Its Genetic Overlap with Other Autoimmune Diseases 由 Roizen, Jeffrey D., Bradfield, Jonathan P., Hakonarson, Hakon

獲取全文 獲取全文 獲取全文

Assessing the functional consequence of loss of function variants using electronic medical record and large-scale genomics consortium efforts 由 Sleiman, Patrick, Bradfield, Jonathan, Mentch, Frank, Almoguera, Berta, Connolly, John, Hakonarson, Hakon

獲取全文 獲取全文 獲取全文

Imputation of TPMT defective alleles for the identification of patients with high-risk phenotypes 由 Almoguera, Berta, Vazquez, Lyam, Connolly, John J., Bradfield, Jonathan, Sleiman, Patrick, Keating, Brendan, Hakonarson, Hakon

獲取全文 獲取全文 獲取全文

Genetics of early-life head circumference and genetic correlations with neurological, psychiatric and cognitive outcomes 由 Vogelezang, Suzanne, Bradfield, Jonathan P., Grant, Struan F. A., Felix, Janine F., Jaddoe, Vincent W. V.

獲取全文 獲取全文 獲取全文

Association Analysis of Type 2 Diabetes Loci in Type 1 Diabetes 由 Qu, Hui-Qi, Grant, Struan F.A., Bradfield, Jonathan P., Kim, Cecilia, Frackelton, Edward, Hakonarson, Hakon, Polychronakos, Constantin

獲取全文 獲取全文 獲取全文

Association of RASGRP1 with type 1 diabetes is revealed by combined follow-up of two genome-wide studies 由 Qu, Hui-Qi, Grant, Struan F.A., Bradfield, Jonathan P., Kim, Cecilia, Frackelton, Edward, Hakonarson, Hakon, Polychronakos, Constantin

獲取全文 獲取全文 獲取全文

Biflavonoid-Induced Disruption of Hydrogen Bonds Leads to Amyloid-β Disaggregation 由 Windsor, Peter K., Plassmeyer, Stephen P., Mattock, Dominic S., Bradfield, Jonathan C., Choi, Erika Y., Miller, Bill R., Han, Byung Hee

獲取全文 獲取全文 獲取全文

Whole-genome DNA/RNA sequencing identifies truncating mutations in RBCK1 in a novel Mendelian disease with neuromuscular and cardiac involvement 由 Wang, Kai, Kim, Cecilia, Bradfield, Jonathan, Guo, Yunfei, Toskala, Elina, Otieno, Frederick G, Hou, Cuiping, Thomas, Kelly, Cardinale, Christopher, Lyon, Gholson J, Golhar, Ryan, Hakonarson, Hakon

獲取全文 獲取全文 獲取全文

Morphine Dose Optimization in Critically Ill Pediatric Patients with Acute Respiratory Failure: A Population Pharmacokinetic-Pharmacogenomic Study 由 Zuppa, Athena F., Benitez, Giselle R., Zane, Nicole R., Curley, Martha A.Q., Bradfield, Jonathan, Hakonarson, Hakon, Gastonguay, Madeleine S., Moorthy, Ganesh, Prodell, Janice, Gastonguay, Marc R.

獲取全文 獲取全文 獲取全文

Combined Application of Genetic and Polygenic Risk Score for Type 1 Diabetes Risk Prediction 由 Qu, Hui-Qi, Qu, Jingchun, Bradfield, Jonathan, Glessner, Joseph, Chang, Xiao, March, Michael, Mentch, Frank D, Roizen, Jeffrey D, Connolly, John J, Sleiman, Patrick, Hakonarson, Hakon

獲取全文 獲取全文 獲取全文

Large Sample Size, Wide Variant Spectrum, and Advanced Machine-Learning Technique Boost Risk Prediction for Inflammatory Bowel Disease 由 Wei, Zhi, Wang, Wei, Bradfield, Jonathan, Li, Jin, Cardinale, Christopher, Frackelton, Edward, Kim, Cecilia, Mentch, Frank, Van Steen, Kristel, Visscher, Peter M., Baldassano, Robert N., Hakonarson, Hakon

獲取全文 獲取全文 獲取全文

GATA Factors Promote ER Integrity and β-Cell Survival and Contribute to Type 1 Diabetes Risk 由 Sartori, Daniel J., Wilbur, Christopher J., Long, Simon Y., Rankin, Matthew M., Li, Changhong, Bradfield, Jonathan P., Hakonarson, Hakon, Grant, Struan F. A., Pu, William T., Kushner, Jake A.

獲取全文 獲取全文 獲取全文

Insights into non-autoimmune type 1 diabetes with 13 novel loci in low polygenic risk score patients 由 Qu, Jingchun, Qu, Hui-Qi, Bradfield, Jonathan P., Glessner, Joseph T., Chang, Xiao, Tian, Lifeng, March, Michael, Connolly, John J., Roizen, Jeffrey D., Sleiman, Patrick M. A., Hakonarson, Hakon

獲取全文 獲取全文 獲取全文

Genetic architecture of type 1 diabetes with low genetic risk score informed by 41 unreported loci 由 Qu, Hui-Qi, Qu, Jingchun, Bradfield, Jonathan, Marchand, Luc, Glessner, Joseph, Chang, Xiao, March, Michael, Li, Jin, Connolly, John J., Roizen, Jeffrey D., Sleiman, Patrick, Polychronakos, Constantin, Hakonarson, Hakon

獲取全文 獲取全文 獲取全文

Mendelian randomization analysis demonstrates that low vitamin D is unlikely causative for pediatric asthma 由 Hysinger, Erik B., Roizen, Jeffrey D., Mentch, Frank D., Vazquez, Lyam, Connolly, John J., Bradfield, Jonathan P., Almoguera, Berta, Sleiman, Patrick M., Allen, Julian L., Levine, Michael A., Hakonarson, Hakon

獲取全文 獲取全文 獲取全文

Dominant Form of Congenital Hyperinsulinism Maps to HK1 Region on 10q 由 Pinney, Sara E., Ganapathy, Karthik, Bradfield, Jonathan, Stokes, David, Sasson, Ariella, Mackiewicz, Katarzyna, Boodhansingh, Kara, Hughes, Nkecha, Becker, Susan, Givler, Stephanie, Macmullen, Courtney, Monos, Dimitrios, Ganguly, Arupa, Hakonarson, Hakon, Stanley, Charles A.

獲取全文 獲取全文 獲取全文

From Disease Association to Risk Assessment: An Optimistic View from Genome-Wide Association Studies on Type 1 Diabetes 由 Wei, Zhi, Wang, Kai, Qu, Hui-Qi, Zhang, Haitao, Bradfield, Jonathan, Kim, Cecilia, Frackleton, Edward, Hou, Cuiping, Glessner, Joseph T., Chiavacci, Rosetta, Stanley, Charles, Monos, Dimitri, Grant, Struan F. A., Polychronakos, Constantin, Hakonarson, Hakon

獲取全文 獲取全文 獲取全文

The Type 2 Diabetes associated rs7903146 T allele within TCF7L2 is significantly under-represented in Hereditary Multiple Exostoses: insights into pathogenesis 由 Sgariglia, Federica, Pedrini, Elena, Bradfield, Jonathan P., Bhatti, Tricia R., D'Adamo, Pio, Dormans, John P., Gunawardena, Aruni T., Hakonarson, Hakon, Hecht, Jacqueline T., Sangiorgi, Luca, Pacifici, Maurizio, Enomoto-Iwamoto, Motomi, Grant, Struan F.A.

獲取全文 獲取全文 獲取全文

Duplication of the SLIT3 Locus on 5q35.1 Predisposes to Major Depressive Disorder 由 Glessner, Joseph T., Wang, Kai, Sleiman, Patrick M. A., Zhang, Haitao, Kim, Cecilia E., Flory, James H., Bradfield, Jonathan P., Imielinski, Marcin, Frackelton, Edward C., Qiu, Haijun, Mentch, Frank, Grant, Struan F. A., Hakonarson, Hakon

獲取全文 獲取全文 獲取全文

A trans-ethnic genome-wide association study identifies gender-specific loci influencing pediatric aBMD and BMC at the distal radius 由 Chesi, Alessandra, Mitchell, Jonathan A., Kalkwarf, Heidi J., Bradfield, Jonathan P., Lappe, Joan M., McCormack, Shana E., Gilsanz, Vicente, Oberfield, Sharon E., Hakonarson, Hakon, Shepherd, John A., Kelly, Andrea, Zemel, Babette S., Grant, Struan F.A.

獲取全文 獲取全文 獲取全文