Bilaketaren emaitzak - Borodovsky, Anna

A novel active site-directed probe specific for deubiquitylating enzymes reveals proteasome association of USP14 nork Borodovsky, Anna, Kessler, Benedikt M., Casagrande, Rocco, Overkleeft, Herman S., Wilkinson, Keith D., Ploegh, Hidde L.

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Integration of the ubiquitin-proteasome pathway with a cytosolic oligopeptidase activity nork Wang, Evelyn W., Kessler, Benedikt M., Borodovsky, Anna, Cravatt, Benjamin F., Bogyo, Matthew, Ploegh, Hidde L., Glas, Rickard

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Pharmacokinetic and Pharmacodynamic Properties of Cemdisiran, an RNAi Therapeutic Targeting Complement Component 5, in Healthy Subjects and Patients with Paroxysmal Nocturnal Hemog... nork Badri, Prajakta, Jiang, Xuemin, Borodovsky, Anna, Najafian, Nader, Kim, Jae, Clausen, Valerie A., Goel, Varun, Habtemariam, Bahru, Robbie, Gabriel J.

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Correction to: Pharmacokinetic and Pharmacodynamic Properties of Cemdisiran, an RNAi Therapeutic Targeting Complement Component 5, in Healthy Subjects and Patients with Paroxysmal... nork Badri, Prajakta, Jiang, Xuemin, Borodovsky, Anna, Najafan, Nader, Kim, Jae, Clausen, Valerie A., Goel, Varun, Habtemariam, Bahru, Robbie, Gabriel J.

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Pharmacokinetics and pharmacodynamics of pozelimab alone or in combination with cemdisiran in non-human primates nork Devalaraja-Narashimha, Kishor, Huang, Cong, Cao, Marc, Chen, Ya Ping, Borodovsky, Anna, Olson, William C., Morton, Lori G., Retter, Marc W.

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An investigational RNAi therapeutic targeting Factor XII (ALN-F12) for the treatment of hereditary angioedema nork Liu, Jingxuan, Qin, June, Borodovsky, Anna, Racie, Timothy, Castoreno, Adam, Schlegel, Mark, Maier, Martin A., Zimmerman, Tracy, Fitzgerald, Kevin, Butler, James, Akinc, Akin

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Investigational RNAi Therapeutic Targeting C5 Is Efficacious in Pre-clinical Models of Myasthenia Gravis nork Kusner, Linda L., Yucius, Kristina, Sengupta, Manjistha, Sprague, Andrew G., Desai, Dhruv, Nguyen, Tuyen, Charisse, Klaus, Kuchimanchi, Satya, Kallanthottathil, Rajeev, Fitzgerald, Kevin, Kaminski, Henry J., Borodovsky, Anna

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Targeting of Liver Mannan-Binding Lectin–Associated Serine Protease-3 with RNA Interference Ameliorates Disease in a Mouse Model of Rheumatoid Arthritis nork Banda, Nirmal K., Desai, Dhruv, Scheinman, Robert I., Pihl, Rasmus, Sekine, Hideharu, Fujita, Teizo, Sharma, Vibha, Hansen, Annette G., Garred, Peter, Thiel, Steffen, Borodovsky, Anna, Holers, V. Michael

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Specific and Covalent Targeting of Conjugating and Deconjugating Enzymes of Ubiquitin-Like Proteins nork Hemelaar, Joris, Borodovsky, Anna, Kessler, Benedikt M., Reverter, David, Cook, Julie, Kolli, Nagamallesawari, Gan-Erdene, Tudev, Wilkinson, Keith D., Gill, Grace, Lima, Christopher D., Ploegh, Hidde L., Ovaa, Huib

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Key Components of the Complement Lectin Pathway Are Not Only Required for the Development of Inflammatory Arthritis but Also Regulate the Transcription of Factor D nork Holers, V. Michael, Borodovsky, Anna, Scheinman, Robert I., Ho, Nhu, Ramirez, Joseline Ramos, Dobó, József, Gál, Péter, Lindenberger, Jared, Hansen, Annette G., Desai, Dhruv, Pihl, Rasmus, Thiel, Steffen, Banda, Nirmal K.

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A Highly Durable RNAi Therapeutic Inhibitor of PCSK9 nork Fitzgerald, Kevin, White, Suellen, Borodovsky, Anna, Bettencourt, Brian R., Strahs, Andrew, Clausen, Valerie, Wijngaard, Peter, Horton, Jay D., Taubel, Jorg, Brooks, Ashley, Fernando, Chamikara, Kauffman, Robert S., Kallend, David, Vaishnaw, Akshay, Simon, Amy

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Polymeric nanoparticle PET/MR imaging allows macrophage detection in atherosclerotic plaques nork Majmudar, Maulik D., Yoo, Jeongsoo, Keliher, Edmund J., Truelove, Jessica, Iwamoto, Yoshiko, Sena, Brena, Dutta, Partha, Borodovsky, Anna, Fitzgerald, Kevin, Di Carli, Marcelo, Libby, Peter, Anderson, Daniel G., Swirski, Filip K., Weissleder, Ralph, Nahrendorf, Matthias

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TL1A–DR3 interaction regulates Th17 cell function and Th17-mediated autoimmune disease nork Pappu, Bhanu P., Borodovsky, Anna, Zheng, Timothy S., Yang, Xuexian, Wu, Ping, Dong, Xingwen, Weng, Shawn, Browning, Beth, Scott, Martin L., Ma, Li, Su, Lihe, Tian, Qiang, Schneider, Pascal, Flavell, Richard A., Dong, Chen, Burkly, Linda C.

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In vivo silencing of the transcription factor IRF5 reprograms the macrophage phenotype and improves infarct healing nork Courties, Gabriel, Heidt, Timo, Sebas, Matthew, Iwamoto, Yoshiko, Jeon, Derrick, Truelove, Jessica, Tricot, Benoit, Wojtkiewicz, Greg, Dutta, Partha, Sager, Hendrik B., Borodovsky, Anna, Novobrantseva, Tatiana, Klebanov, Boris, Fitzgerald, Kevin, Anderson, Daniel G, Libby, Peter, Swirski, Filip K., Weissleder, Ralph, Nahrendorf, Matthias

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Proliferation and recruitment contribute to myocardial macrophage expansion in chronic heart failure nork Sager, Hendrik B., Hulsmans, Maarten, Lavine, Kory J., Moreira, Marina B., Heidt, Timo, Courties, Gabriel, Sun, Yuan, Iwamoto, Yoshiko, Tricot, Benoit, Khan, Omar F., Dahlman, James E., Borodovsky, Anna, Fitzgerald, Kevin, Anderson, Daniel G., Weissleder, Ralph, Libby, Peter, Swirski, Filip K., Nahrendorf, Matthias

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Molecularly Self-Assembled Nucleic Acid Nanoparticles for Targeted In Vivo siRNA Delivery nork Lee, Hyukjin, Lytton-Jean, Abigail K. R., Chen, Yi, Love, Kevin T., Park, Angela I., Karagiannis, Emmanouil D., Sehgal, Alfica, Querbes, William, Zurenko, Christopher S., Jayaraman, Muthusamy, Peng, Chang G., Charisse, Klaus, Borodovsky, Anna, Manoharan, Muthiah, Donahoe, Jessica S., Truelove, Jessica, Nahrendorf, Matthias, Langer, Robert, Anderson, Daniel G.

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Macrophages retain hematopoietic stem cells in the spleen via VCAM-1 nork Dutta, Partha, Hoyer, Friedrich Felix, Grigoryeva, Lubov S., Sager, Hendrik B., Leuschner, Florian, Courties, Gabriel, Borodovsky, Anna, Novobrantseva, Tatiana, Ruda, Vera M., Fitzgerald, Kevin, Iwamoto, Yoshiko, Wojtkiewicz, Gregory, Sun, Yuan, Da Silva, Nicolas, Libby, Peter, Anderson, Daniel G., Swirski, Filip K., Weissleder, Ralph, Nahrendorf, Matthias

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Monocyte-directed RNAi targeting CCR2 improves infarct healing in atherosclerosis-prone mice nork Majmudar, Maulik D., Keliher, Edmund J., Heidt, Timo, Leuschner, Florian, Truelove, Jessica, Sena, Brena F., Gorbatov, Rostic, Iwamoto, Yoshiko, Dutta, Partha, Wojtkiewicz, Gregory, Courties, Gabriel, Sebas, Matt, Borodovsky, Anna, Fitzgerald, Kevin, Nolte, Marc W., Dickneite, Gerhard, Chen, John W., Anderson, Daniel G., Swirski, Filip K., Weissleder, Ralph, Nahrendorf, Matthias

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Silencing of CCR2 in myocarditis nork Leuschner, Florian, Courties, Gabriel, Dutta, Partha, Mortensen, Luke J., Gorbatov, Rostic, Sena, Brena, Novobrantseva, Tatiana I., Borodovsky, Anna, Fitzgerald, Kevin, Koteliansky, Victor, Iwamoto, Yoshiko, Bohlender, Marina, Meyer, Soeren, Lasitschka, Felix, Meder, Benjamin, Katus, Hugo A., Lin, Charles, Libby, Peter, Swirski, Filip K., Anderson, Daniel G., Weissleder, Ralph, Nahrendorf, Matthias

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RNAi targeting multiple cell adhesion molecules reduces immune cell recruitment and vascular inflammation after myocardial infarction nork Sager, Hendrik B., Dutta, Partha, Dahlman, James E., Hulsmans, Maarten, Courties, Gabriel, Sun, Yuan, Heidt, Timo, Vinegoni, Claudio, Borodovsky, Anna, Fitzgerald, Kevin, Wojtkiewicz, Gregory R., Iwamoto, Yoshiko, Tricot, Benoit, Khan, Omar F., Kauffman, Kevin J., Xing, Yiping, Shaw, Taylor E., Libby, Peter, Langer, Robert, Weissleder, Ralph, Swirski, Filip K., Anderson, Daniel G., Nahrendorf, Matthias

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