نتائج البحث - Bornhauser, Beat

Exploiting Necroptosis for Therapy of Acute Lymphoblastic Leukemia حسب Mezzatesta, Caterina, Bornhauser, Beat C.

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Tissue Expression and Actin Binding of a Novel N-Terminal Utrophin Isoform حسب Zuellig, Richard A., Bornhauser, Beat C., Amstutz, Ralf, Constantin, Bruno, Schaub, Marcus C.

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Rapid Generation of Leukemogenic Chromosomal Translocations in Vivo Using CRISPR/Cas9 حسب Huang, Yun, Marovca, Blerim, Dettwiler, Susanne, Bode, Peter Karl, Bornhauser, Beat, Bourquin, Jean-Pierre

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PDGF regulates the actin cytoskeleton through hnRNP-K-mediated activation of the ubiquitin E(3)-ligase MIR حسب Nagano, Kohji, Bornhauser, Beat C, Warnasuriya, Gayathri, Entwistle, Alan, Cramer, Rainer, Lindholm, Dan, Naaby-Hansen, Soren

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High Immunoproteasome Activity and sXBP1 in Pediatric Precursor B-ALL Predicts Sensitivity towards Proteasome Inhibitors حسب Besse, Lenka, Besse, Andrej, Kraus, Marianne, Maurits, Elmer, Overkleeft, Herman S., Bornhauser, Beat, Bourquin, Jean-Pierre, Driessen, Christoph

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Venetoclax and Bortezomib in Relapsed/Refractory Early T-Cell Precursor Acute Lymphoblastic Leukemia حسب La Starza, Roberta, Cambò, Benedetta, Pierini, Antonio, Bornhauser, Beat, Montanaro, Anna, Bourquin, Jean-Pierre, Mecucci, Cristina, Roti, Giovanni

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Efficient apoptosis requires feedback amplification of upstream apoptotic signals by effector caspase-3 or -7 حسب McComb, Scott, Chan, Pik Ki, Guinot, Anna, Hartmannsdottir, Holmfridur, Jenni, Silvia, Dobay, Maria Pamela, Bourquin, Jean-Pierre, Bornhauser, Beat C.

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Efficient Generation of Multi-gene Knockout Cell Lines and Patient-derived Xenografts Using Multi-colored Lenti-CRISPR-Cas9 حسب Behrmann, Lena, McComb, Scott, Aguadé-Gorgorió, Júlia, Huang, Yun, Hermann, Mario, Pelczar, Pawel, Aguzzi, Adriano, Bourquin, Jean-Pierre, Bornhauser, Beat C.

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Fibroblast Growth Factor-21 (FGF21) Regulates Low-density Lipoprotein Receptor (LDLR) Levels in Cells via the E3-ubiquitin Ligase Mylip/Idol and the Canopy2 (Cnpy2)/Mylip-interacti... حسب Do, Hai Thi, Tselykh, Timofey V., Mäkelä, Johanna, Ho, Tho Huu, Olkkonen, Vesa M., Bornhauser, Beat C., Korhonen, Laura, Zelcer, Noam, Lindholm, Dan

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Induction of autophagy-dependent necroptosis is required for childhood acute lymphoblastic leukemia cells to overcome glucocorticoid resistance حسب Bonapace, Laura, Bornhauser, Beat C., Schmitz, Maike, Cario, Gunnar, Ziegler, Urs, Niggli, Felix K., Schäfer, Beat W., Schrappe, Martin, Stanulla, Martin, Bourquin, Jean-Pierre

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Image-based RNA interference screening reveals an individual dependence of acute lymphoblastic leukemia on stromal cysteine support حسب Boutter, Jeannette, Huang, Yun, Marovca, Blerim, Vonderheit, Andreas, Grotzer, Michael A., Eckert, Cornelia, Cario, Gunnar, Wollscheid, Bernd, Horvath, Peter, Bornhauser, Beat C., Bourquin, Jean-Pierre

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Clinical or ATPase domain mutations in ABCD4 disrupt the interaction between the vitamin B(12)-trafficking proteins ABCD4 and LMBD1 حسب Fettelschoss, Victoria, Burda, Patricie, Sagné, Corinne, Coelho, David, De Laet, Corinne, Lutz, Seraina, Suormala, Terttu, Fowler, Brian, Pietrancosta, Nicolas, Gasnier, Bruno, Bornhauser, Beat, Froese, D. Sean, Baumgartner, Matthias R.

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CD133 Positive Embryonal Rhabdomyosarcoma Stem-Like Cell Population Is Enriched in Rhabdospheres حسب Walter, Dagmar, Satheesha, Sampoorna, Albrecht, Patrick, Bornhauser, Beat C., D'Alessandro, Valentina, Oesch, Susanne M., Rehrauer, Hubert, Leuschner, Ivo, Koscielniak, Ewa, Gengler, Carole, Moch, Holger, Bernasconi, Michele, Niggli, Felix K., Schäfer, Beat W.

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Frequency and prognostic impact of ZEB2 H1038 and Q1072 mutations in childhood B-other acute lymphoblastic leukemia حسب Zaliova, Marketa, Potuckova, Eliska, Lukes, Julius, Winkowska, Lucie, Starkova, Julia, Janotova, Iveta, Sramkova, Lucie, Stary, Jan, Zuna, Jan, Stanulla, Martin, Zimmermann, Martin, Bornhauser, Beat, Bourquin, Jean-Pierre, Eckert, Cornelia, Cario, Gunnar, Trka, Jan

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TNFR2 is required for RIP1-dependent cell death in human leukemia حسب Aguadé-Gorgorió, Júlia, McComb, Scott, Eckert, Cornelia, Guinot, Anna, Marovca, Blerim, Mezzatesta, Caterina, Jenni, Silvia, Abduli, Liridon, Schrappe, Martin, Dobay, Maria Pamela, Stanulla, Martin, von Stackelberg, Arend, Cario, Gunnar, Bourquin, Jean-Pierre, Bornhauser, Beat C.

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Cooperative Enhancer Activation by TLX1 and STAT5 Drives Development of NUP214-ABL1/TLX1-Positive T Cell Acute Lymphoblastic Leukemia حسب Vanden Bempt, Marlies, Demeyer, Sofie, Broux, Michaël, De Bie, Jolien, Bornschein, Simon, Mentens, Nicole, Vandepoel, Roel, Geerdens, Ellen, Radaelli, Enrico, Bornhauser, Beat C., Kulozik, Andreas E., Meijerink, Jules P., Bourquin, Jean-Pierre, de Bock, Charles E., Cools, Jan

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Repurposing anthelmintic agents to eradicate resistant leukemia حسب Mezzatesta, Caterina, Abduli, Liridon, Guinot, Anna, Eckert, Cornelia, Schewe, Denis, Zaliova, Marketa, Vinti, Luciana, Marovca, Blerim, Tsai, Yi-Chien, Jenni, Silvia, Aguade-Gorgorio, Julia, von Stackelberg, Arend, Schrappe, Martin, Locatelli, Franco, Stanulla, Martin, Cario, Gunnar, Bourquin, Jean-Pierre, Bornhauser, Beat C.

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BTK inhibition sensitizes acute lymphoblastic leukemia to asparaginase by suppressing the amino acid response pathway حسب Butler, Miriam, van Ingen Schenau, Dorette S., Yu, Jiangyan, Jenni, Silvia, Dobay, Maria P., Hagelaar, Rico, Vervoort, Britt M. T., Tee, Trisha M., Hoff, Fieke W., Meijerink, Jules P., Kornblau, Steven M., Bornhauser, Beat, Bourquin, Jean-Pierre, Kuiper, Roland P., van der Meer, Laurens T., van Leeuwen, Frank N.

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Pharmacological disruption of the Notch transcription factor complex حسب Lehal, Rajwinder, Zaric, Jelena, Vigolo, Michele, Urech, Charlotte, Frismantas, Viktoras, Zangger, Nadine, Cao, Linlin, Berger, Adeline, Chicote, Irene, Loubéry, Sylvain, Choi, Sung Hee, Koch, Ute, Blacklow, Stephen C., Palmer, Hector G., Bornhauser, Beat, González-Gaitán, Marcos, Arsenijevic, Yvan, Zoete, Vincent, Aster, Jon C., Bourquin, Jean-Pierre, Radtke, Freddy

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Cell and Molecular Determinants of In Vivo Efficacy of the BH3 Mimetic ABT-263 Against Pediatric Acute Lymphoblastic Leukemia Xenografts حسب Suryani, Santi, Carol, Hernan, Chonghaile, Triona Ni, Frismantas, Viktoras, Sarmah, Chintanu, High, Laura, Bornhauser, Beat, Cowley, Mark J, Szymanska, Barbara, Evans, Kathryn, Boehm, Ingrid, Tonna, Elise, Jones, Luke, Manesh, Donya Moradi, Kurmasheva, Raushan T., Billups, Catherine, Kaplan, Warren, Letai, Anthony, Bourquin, Jean-Pierre, Houghton, Peter J, Smith, Malcolm A, Lock, Richard B

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