Canlyniadau Chwilio - Bogenrieder, Thomas

Cell-surface proteolysis, growth factor activation and intercellular communication in the progression of melanoma gan Bogenrieder, Thomas, Herlyn, Meenhard

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Insulin-Like Growth Factor (IGF) Pathway Targeting in Cancer: Role of the IGF Axis and Opportunities for Future Combination Studies gan Simpson, Aaron, Petnga, Wilfride, Macaulay, Valentine M., Weyer-Czernilofsky, Ulrike, Bogenrieder, Thomas

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Blockade of insulin-like growth factors increases efficacy of paclitaxel in metastatic breast cancer gan Ireland, Lucy, Santos, Almudena, Campbell, Fiona, Figueiredo, Carlos, Hammond, Dean, Ellies, Lesley G., Weyer-Czernilofsky, Ulrike, Bogenrieder, Thomas, Schmid, Michael, Mielgo, Ainhoa

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CHK1 inhibition exacerbates replication stress induced by IGF blockade gan Wu, Xiaoning, Seraia, Elena, Hatch, Stephanie B., Wan, Xiao, Ebner, Daniel V., Aroldi, Francesca, Jiang, Yanyan, Ryan, Anderson J., Bogenrieder, Thomas, Weyer-Czernilofsky, Ulrike, Rieunier, Guillaume, Macaulay, Valentine M.

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Regulation of proliferation and invasion by the IGF signalling pathway in Epstein‐Barr virus‐positive gastric cancer gan Jeong, Inhye, Kang, Sun Kyoung, Kwon, Woo Sun, Kim, Hyun Jeong, Kim, Kyoo Hyun, Kim, Hyun Myong, Lee, Andre, Lee, Suk Kyeong, Bogenrieder, Thomas, Chung, Hyun Cheol, Rha, Sun Young

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Phase 1b Open-Label Trial of Afatinib Plus Xentuzumab (BI 836845) in Patients With EGFR Mutation-Positive NSCLC After Progression on EGFR Tyrosine Kinase Inhibitors gan Park, Keunchil, Tan, Daniel Shao Weng, Su, Wu-Chou, Cho, Byoung Chul, Kim, Sang-We, Lee, Ki Hyeong, Wang, Chin-Chou, Seto, Takashi, Huang, Dennis Chin-Lun, Jung, Helen Hayoun, Hsu, Ming-Chi, Bogenrieder, Thomas, Lin, Chia-Chi

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Chemoresistance in Pancreatic Cancer Is Driven by Stroma-Derived Insulin-Like Growth Factors gan Ireland, Lucy, Santos, Almudena, Ahmed, Muhammad S., Rainer, Carolyn, Nielsen, Sebastian R., Quaranta, Valeria, Weyer-Czernilofsky, Ulrike, Engle, Danielle D., Perez-Mancera, Pedro A., Coupland, Sarah E., Taktak, Azzam, Bogenrieder, Thomas, Tuveson, David A., Campbell, Fiona, Schmid, Michael C., Mielgo, Ainhoa

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Nuclear IGF-1R interacts with regulatory regions of chromatin to promote RNA polymerase II recruitment and gene expression associated with advanced tumor stage gan Aleksic, Tamara, Gray, Nicki, Wu, Xiaoning, Rieunier, Guillaume, Osher, Eliot, Mills, Jack, Verrill, Clare, Bryant, Richard J., Han, Cheng, Hutchinson, Kathryn, Lambert, Adam G., Kumar, Rajeev, Hamdy, Freddie C., Weyer-Czernilofsky, Ulrike, Sanderson, Michael P., Bogenrieder, Thomas, Taylor, Stephen, Macaulay, Valentine M.

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A phase Ib/II study of xentuzumab, an IGF-neutralising antibody, combined with exemestane and everolimus in hormone receptor-positive, HER2-negative locally advanced/metastatic bre... gan Schmid, Peter, Sablin, Marie-Paule, Bergh, Jonas, Im, Seock-Ah, Lu, Yen-Shen, Martínez, Noelia, Neven, Patrick, Lee, Keun Seok, Morales, Serafín, Pérez-Fidalgo, J. Alejandro, Adamson, Douglas, Gonçalves, Anthony, Prat, Aleix, Jerusalem, Guy, Schlieker, Laura, Espadero, Rosa-Maria, Bogenrieder, Thomas, Huang, Dennis Chin-Lun, Crown, John, Cortés, Javier

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Two first-in-human studies of xentuzumab, a humanised insulin-like growth factor (IGF)-neutralising antibody, in patients with advanced solid tumours gan de Bono, Johann, Lin, Chia-Chi, Chen, Li-Tzong, Corral, Jesus, Michalarea, Vasiliki, Rihawi, Karim, Ong, Michael, Lee, Jih-Hsiang, Hsu, Chih-Hung, Yang, James Chih-Hsin, Shiah, Her-Shyong, Yen, Chia-Jui, Anthoney, Alan, Jove, Maria, Buschke, Susanne, Fuertig, René, Schmid, Ulrike, Goeldner, Rainer-Georg, Strelkowa, Natalja, Huang, Dennis Chin-Lun, Bogenrieder, Thomas, Twelves, Chris, Cheng, Ann-Lii

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