Rezultati - Blessing C. Ogboo
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Pitfalls and Considerations in Determining the Potency and Mutant Selectivity of Covalent Epidermal Growth Factor Receptor Inhibitors od Kristopher W. Hoyt, Daniel A. Urul, Blessing C. Ogboo, Florian Wittlinger, Stefan Laufer, Erik Schaefer, Earl W. May, David E. Heppner
Izdano 2023Artigo -
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Structural Basis for Inhibition of Mutant EGFR with Lazertinib (YH25448) od David E. Heppner, Florian Wittlinger, Tyler S. Beyett, Tatiana Shaurova, Daniel A. Urul, Brian Buckley, Calvin D. Pham, Ilse K. Schaeffner, Bo Yang, Blessing C. Ogboo, Earl W. May, Erik Schaefer, Michael J. Eck, Stefan Laufer, Pamela A. Hershberger
Izdano 2022Artigo -
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Linking ATP and allosteric sites to achieve superadditive binding with bivalent EGFR kinase inhibitors od Florian Wittlinger, Blessing C. Ogboo, Ekaterina Shevchenko, Tahereh Damghani, Calvin D. Pham, Ilse K. Schaeffner, Brandon T. Oligny, Surbhi P. Chitnis, Tyler S. Beyett, Alexander Rasch, Brian Buckley, Daniel A. Urul, Tatiana Shaurova, Earl W. May, Erik Schaefer, Michael J. Eck, Pamela A. Hershberger, Antti Poso, Stefan Laufer, David E. Heppner
Izdano 2024Artigo
Iskalna orodja:
Sorodne teme
Biochemistry
Biology
Chemistry
Organic chemistry
Biophysics
Combinatorial chemistry
Enzyme
Computational biology
EGFR inhibitors
Epidermal growth factor receptor
Molecule
Receptor
Stereochemistry
Afatinib
Allosteric regulation
Binding site
Bivalent (engine)
Cancer research
Cell biology
Computer science
Covalent bond
Cryo-electron microscopy
Cytosol
Electron transfer
Engineering
Erlotinib
Extracellular
Gefitinib
Gene
Hydrogen bond