Søgeresultater - Blessing C. Ogboo
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Pitfalls and Considerations in Determining the Potency and Mutant Selectivity of Covalent Epidermal Growth Factor Receptor Inhibitors af Kristopher W. Hoyt, Daniel A. Urul, Blessing C. Ogboo, Florian Wittlinger, Stefan Laufer, Erik Schaefer, Earl W. May, David E. Heppner
Udgivet 2023Artigo -
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Structural Basis for Inhibition of Mutant EGFR with Lazertinib (YH25448) af David E. Heppner, Florian Wittlinger, Tyler S. Beyett, Tatiana Shaurova, Daniel A. Urul, Brian Buckley, Calvin D. Pham, Ilse K. Schaeffner, Bo Yang, Blessing C. Ogboo, Earl W. May, Erik Schaefer, Michael J. Eck, Stefan Laufer, Pamela A. Hershberger
Udgivet 2022Artigo -
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Linking ATP and allosteric sites to achieve superadditive binding with bivalent EGFR kinase inhibitors af Florian Wittlinger, Blessing C. Ogboo, Ekaterina Shevchenko, Tahereh Damghani, Calvin D. Pham, Ilse K. Schaeffner, Brandon T. Oligny, Surbhi P. Chitnis, Tyler S. Beyett, Alexander Rasch, Brian Buckley, Daniel A. Urul, Tatiana Shaurova, Earl W. May, Erik Schaefer, Michael J. Eck, Pamela A. Hershberger, Antti Poso, Stefan Laufer, David E. Heppner
Udgivet 2024Artigo
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Relaterede emner
Biochemistry
Biology
Chemistry
Organic chemistry
Biophysics
Combinatorial chemistry
Enzyme
Computational biology
EGFR inhibitors
Epidermal growth factor receptor
Molecule
Receptor
Stereochemistry
Afatinib
Allosteric regulation
Binding site
Bivalent (engine)
Cancer research
Cell biology
Computer science
Covalent bond
Cryo-electron microscopy
Cytosol
Electron transfer
Engineering
Erlotinib
Extracellular
Gefitinib
Gene
Hydrogen bond