Risultati della ricerca - Blessing C. Ogboo
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1
Architecture of the NADPH oxidase family of enzymes di Blessing C. Ogboo, Uriy V. Grabovyy, Aniket Maini, Scott Scouten, Albert van der Vliet, Andrea Mattevi, David E. Heppner
Pubblicazione 2022Revisão -
2
Pitfalls and Considerations in Determining the Potency and Mutant Selectivity of Covalent Epidermal Growth Factor Receptor Inhibitors di Kristopher W. Hoyt, Daniel A. Urul, Blessing C. Ogboo, Florian Wittlinger, Stefan Laufer, Erik Schaefer, Earl W. May, David E. Heppner
Pubblicazione 2023Artigo -
3
Structural Basis for Inhibition of Mutant EGFR with Lazertinib (YH25448) di David E. Heppner, Florian Wittlinger, Tyler S. Beyett, Tatiana Shaurova, Daniel A. Urul, Brian Buckley, Calvin D. Pham, Ilse K. Schaeffner, Bo Yang, Blessing C. Ogboo, Earl W. May, Erik Schaefer, Michael J. Eck, Stefan Laufer, Pamela A. Hershberger
Pubblicazione 2022Artigo -
4
Linking ATP and allosteric sites to achieve superadditive binding with bivalent EGFR kinase inhibitors di Florian Wittlinger, Blessing C. Ogboo, Ekaterina Shevchenko, Tahereh Damghani, Calvin D. Pham, Ilse K. Schaeffner, Brandon T. Oligny, Surbhi P. Chitnis, Tyler S. Beyett, Alexander Rasch, Brian Buckley, Daniel A. Urul, Tatiana Shaurova, Earl W. May, Erik Schaefer, Michael J. Eck, Pamela A. Hershberger, Antti Poso, Stefan Laufer, David E. Heppner
Pubblicazione 2024Artigo
Strumenti per la ricerca:
Soggetti correlati
Biochemistry
Biology
Chemistry
Organic chemistry
Biophysics
Combinatorial chemistry
Enzyme
Computational biology
EGFR inhibitors
Epidermal growth factor receptor
Molecule
Receptor
Stereochemistry
Afatinib
Allosteric regulation
Binding site
Bivalent (engine)
Cancer research
Cell biology
Computer science
Covalent bond
Cryo-electron microscopy
Cytosol
Electron transfer
Engineering
Erlotinib
Extracellular
Gefitinib
Gene
Hydrogen bond