Výsledky vyhledávání - Birgit Schoeberl

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  1. 1
    Competing Docking Interactions can Bring About Bistability in the MAPK Cascade

    Competing Docking Interactions can Bring About Bistability in the MAPK Cascade Autor Stefan Legewie, Birgit Schoeberl, Nils Blüthgen, Hanspeter Herzel

    Vydáno 2007
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  2. 2
    Human Cytochrome P450 1, 2, 3 Families as Pharmacogenes with Emphases on Their Antimalarial and Antituberculosis Drugs and Prevalent African Alleles

    Human Cytochrome P450 1, 2, 3 Families as Pharmacogenes with Emphases on Their Antimalarial and Antituberculosis Drugs and Prevalent African Alleles Autor Chiratidzo R. Chamboko, Wayde Veldman, Rolland Bantar Tata, Birgit Schoeberl, Özlem Taştan Bishop

    Vydáno 2023
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  3. 3
    Autocrine signaling is a key regulatory element during osteoclastogenesis

    Autocrine signaling is a key regulatory element during osteoclastogenesis Autor Paul W. Kopesky, Kerstin Tiedemann, Dahlia Alkekhia, Christoph Zechner, Bjorn L. Millard, Birgit Schoeberl, Svetlana V. Komarova

    Vydáno 2014
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  4. 4
    Estimation of immune cell content in tumour tissue using single-cell RNA-seq data

    Estimation of immune cell content in tumour tissue using single-cell RNA-seq data Autor Max Schelker, Sonia Feau, Jinyan Du, Nav Ranu, Edda Klipp, Gavin MacBeath, Birgit Schoeberl, Andreas Raue

    Vydáno 2017
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  5. 5
    Input–output behavior of ErbB signaling pathways as revealed by a mass action model trained against dynamic data

    Input–output behavior of ErbB signaling pathways as revealed by a mass action model trained against dynamic data Autor William W. Chen, Birgit Schoeberl, Paul Jasper, Mario Niepel, Ulrik B. Nielsen, Douglas A. Lauffenburger, Peter K. Sorger

    Vydáno 2009
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  6. 6
    HER2+ Cancer Cell Dependence on PI3K vs. MAPK Signaling Axes Is Determined by Expression of EGFR, ERBB3 and CDKN1B

    HER2+ Cancer Cell Dependence on PI3K vs. MAPK Signaling Axes Is Determined by Expression of EGFR, ERBB3 and CDKN1B Autor Daniel C. Kirouac, Jinyan Du, Johanna Lahdenranta, Matthew Onsum, Ulrik B. Nielsen, Birgit Schoeberl, Charlotte F. McDonagh

    Vydáno 2016
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  7. 7
    Modeling chemotherapy-induced stress to identify rational combination therapies in the DNA damage response pathway

    Modeling chemotherapy-induced stress to identify rational combination therapies in the DNA damage response pathway Autor Ozan Alkan, Birgit Schoeberl, Millie Shah, Alexander Koshkaryev, Tim Heinemann, Daryl C. Drummond, Michael B. Yaffe, Andreas Raue

    Vydáno 2018
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  8. 8
    Profiles of Basal and Stimulated Receptor Signaling Networks Predict Drug Response in Breast Cancer Lines

    Profiles of Basal and Stimulated Receptor Signaling Networks Predict Drug Response in Breast Cancer Lines Autor Mario Niepel, Marc Hafner, Emily A. Pace, Mirra Chung, Diana H. Chai, Lili Zhou, Birgit Schoeberl, Peter K. Sorger

    Vydáno 2013
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  9. 9
    Impact of Intrinsic Affinity on Functional Binding and Biological Activity of EGFR Antibodies

    Impact of Intrinsic Affinity on Functional Binding and Biological Activity of EGFR Antibodies Autor Yu Zhou, Anne-Laure Goenaga, Brian D. Harms, Hao Zou, Jianlong Lou, Fraser Conrad, Gregory P. Adams, Birgit Schoeberl, Ulrik B. Nielsen, James D. Marks

    Vydáno 2012
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  10. 10
    An ErbB3 Antibody, MM-121, Is Active in Cancers with Ligand-Dependent Activation

    An ErbB3 Antibody, MM-121, Is Active in Cancers with Ligand-Dependent Activation Autor Birgit Schoeberl, Anthony C. Faber, Danan Li, Mei‐Chih Liang, Katherine Crosby, Matthew Onsum, Olga Burenkova, Emily Pace, Zandra E. Walton, Lin Nie, Aaron Fulgham, Youngchul Song, Ulrik B. Nielsen, Jeffrey A. Engelman, Kwok‐Kin Wong

    Vydáno 2010
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  11. 11
    MM-141, an IGF-IR– and ErbB3-Directed Bispecific Antibody, Overcomes Network Adaptations That Limit Activity of IGF-IR Inhibitors

    MM-141, an IGF-IR– and ErbB3-Directed Bispecific Antibody, Overcomes Network Adaptations That Limit Activity of IGF-IR Inhibitors Autor Jonathan B. Fitzgerald, Bryan W. Johnson, Jason Baum, Sharlene Adams, Sergio Iadevaia, Jian Tang, Victoria Rimkunas, Lihui Xu, Neeraj Kohli, Rachel Rennard, Maja Razlog, Yang Jiao, Brian D. Harms, Kenneth J. Olivier, Birgit Schoeberl, Ulrik B. Nielsen, Alexey A. Lugovskoy

    Vydáno 2013
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  12. 12
    Antitumor Activity of a Novel Bispecific Antibody That Targets the ErbB2/ErbB3 Oncogenic Unit and Inhibits Heregulin-Induced Activation of ErbB3

    Antitumor Activity of a Novel Bispecific Antibody That Targets the ErbB2/ErbB3 Oncogenic Unit and Inhibits Heregulin-Induced Activation of ErbB3 Autor Charlotte F. McDonagh, Alexandra Huhalov, Brian D. Harms, Sharlene Adams, Violette Paragas, Shinji Oyama, Bo Zhang, Lia Luus, Ryan Overland, Stephanie A. Nguyen, Jinming Gu, Neeraj Kohli, Matt Wallace, Michael J. Feldhaus, Arthur J. Kudla, Birgit Schoeberl, Ulrik B. Nielsen

    Vydáno 2012
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  13. 13
    An Activated ErbB3/NRG1 Autocrine Loop Supports In Vivo Proliferation in Ovarian Cancer Cells

    An Activated ErbB3/NRG1 Autocrine Loop Supports In Vivo Proliferation in Ovarian Cancer Cells Autor Qing Sheng, Xinggang Liu, Eleanor Fleming, Karen Yuan, Huiying Piao, Jinyun Chen, Zeinab Moustafa, Roman K. Thomas, Heidi Greulich, Anna C. Schinzel, Sara Zaghlul, David Batt, Seth A. Ettenberg, Matthew Meyerson, Birgit Schoeberl, Andrew L. Kung, William C. Hahn, Ronny Drapkin, David M. Livingston, Joyce F. Liu

    Vydáno 2010
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  14. 14
    Dual Inhibition of IGF-1R and ErbB3 Enhances the Activity of Gemcitabine and Nab-Paclitaxel in Preclinical Models of Pancreatic Cancer

    Dual Inhibition of IGF-1R and ErbB3 Enhances the Activity of Gemcitabine and Nab-Paclitaxel in Preclinical Models of Pancreatic Cancer Autor Adam J. Camblin, Emily A. Pace, Sharlene Adams, Michael D. Curley, Victoria Rimkunas, Lin Nie, Gege Tan, Troy Bloom, Sergio Iadevaia, Jason Baum, Charlene Minx, Akos Czibere, Chrystal U. Louis, Daryl C. Drummond, Ulrik B. Nielsen, Birgit Schoeberl, J. Marc Pipas, Robert M. Straubinger, Vasileios Askoxylakis, Alexey A. Lugovskoy

    Vydáno 2018
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  15. 15
    Systems biology driving drug development: from design to the clinical testing of the anti-ErbB3 antibody seribantumab (MM-121)

    Systems biology driving drug development: from design to the clinical testing of the anti-ErbB3 antibody seribantumab (MM-121) Autor Birgit Schoeberl, Art Kudla, Kristina Masson, Ashish Kalra, Michael Curley, Gregory J. Finn, Emily Pace, Brian D. Harms, Jaeyeon Kim, Kearns Jeff, Aaron Fulgham, Olga Burenkova, Viara Grantcharova, Defne Yarar, Violette Paragas, Jonathan B. Fitzgerald, Marisa J. Wainszelbaum, Kip A. West, Sara Mathews, Rachel Nering, Bambang S. Adiwijaya, Gabriela Garcia, Bill Kubasek, Victor Moyo, Akos Czibere, Ulrik B. Nielsen, Gavin MacBeath

    Vydáno 2017
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