Resultados de búsqueda - Birgit Knoechel

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  1. 1
    Balancing autoaggressive and protective T cell responses

    Balancing autoaggressive and protective T cell responses por Abul K. Abbas, Jens G. Lohr, Birgit Knoechel

    Publicado 2007
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  2. 2
    IL-2 Induces a Competitive Survival Advantage in T Lymphocytes

    IL-2 Induces a Competitive Survival Advantage in T Lymphocytes por Hans Dooms, Estelle Kahn, Birgit Knoechel, Abul K. Abbas

    Publicado 2004
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  3. 3
    Role of B7 in T Cell Tolerance

    Role of B7 in T Cell Tolerance por Jens G. Lohr, Birgit Knoechel, Estelle Kahn, Abul K. Abbas

    Publicado 2004
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  4. 4
    Sequential development of interleukin 2–dependent effector and regulatory T cells in response to endogenous systemic antigen

    Sequential development of interleukin 2–dependent effector and regulatory T cells in response to endogenous systemic antigen por Birgit Knoechel, Jens G. Lohr, Estelle Kahn, Jeffrey A. Bluestone, Abul K. Abbas

    Publicado 2005
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  5. 5
    Role of IL-17 and regulatory T lymphocytes in a systemic autoimmune disease

    Role of IL-17 and regulatory T lymphocytes in a systemic autoimmune disease por Jens G. Lohr, Birgit Knoechel, Jing Jing Wang, Alejandro V. Villarino, Abul K. Abbas

    Publicado 2006
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  6. 6
    Zebrafish blastomere screen identifies retinoic acid suppression of <i>MYB</i> in adenoid cystic carcinoma

    Zebrafish blastomere screen identifies retinoic acid suppression of <i>MYB</i> in adenoid cystic carcinoma por Joseph Mandelbaum, Ilya Shestopalov, Rachel E. Henderson, Nicole G. Chau, Birgit Knoechel, Michael J. Wick, Leonard I. Zon

    Publicado 2018
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  7. 7
    Peptidomimetic blockade of MYB in acute myeloid leukemia

    Peptidomimetic blockade of MYB in acute myeloid leukemia por Kavitha Ramaswamy, Lauren Forbes, Gerard Minuesa, Tatyana Gindin, Fiona C. Brown, Michael G. Kharas, Andrei V. Krivtsov, Scott A. Armstrong, Eric Still, Elisa de Stanchina, Birgit Knoechel, Richard P. Koche, Alex Kentsis

    Publicado 2018
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  8. 8
    Genetic interrogation of circulating multiple myeloma cells at single-cell resolution

    Genetic interrogation of circulating multiple myeloma cells at single-cell resolution por Jens G. Lohr, Sora Kim, Joshua Gould, Birgit Knoechel, Yotam Drier, Matthew J. Cotton, Daniel H.D. Gray, Nicole Birrer, Bang Wong, Gavin Ha, Cheng-Zhong Zhang, Guangwu Guo, Matthew Meyerson, Andrew J. Yee, Jesse S. Boehm, Noopur Raje, Todd R. Golub

    Publicado 2016
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  9. 9
    Complete hematologic response of early T-cell progenitor acute lymphoblastic leukemia to the γ-secretase inhibitor BMS-906024: genetic and epigenetic findings in an outlier case

    Complete hematologic response of early T-cell progenitor acute lymphoblastic leukemia to the γ-secretase inhibitor BMS-906024: genetic and epigenetic findings in an outlier case por Birgit Knoechel, Ami S. Bhatt, Pan Li, Chandra Sekhar Pedamallu, Eric A. Severson, Alejandro Gutiérrez, David M. Dorfman, Frank C. Kuo, Michael Kluk, Andrew L. Kung, Patrick A. Zweidler‐McKay, Matthew Meyerson, Stephen C. Blacklow, Daniel J. DeAngelo, Jon C. Aster

    Publicado 2015
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  10. 10
    Long-range enhancer activity determines <i>Myc</i> sensitivity to Notch inhibitors in T cell leukemia

    Long-range enhancer activity determines <i>Myc</i> sensitivity to Notch inhibitors in T cell leukemia por Yumi Yashiro–Ohtani, Hongfang Wang, Chongzhi Zang, Kelly L. Arnett, Will Bailis, Yugong Ho, Birgit Knoechel, Claudia Lanauze, Lumena Louis, Katherine S. Forsyth, Sujun Chen, Yoonjie Chung, Jonathan Schug, Gerd A. Blobel, Stephen A. Liebhaber, B Bernstein, Stephen C. Blacklow, Xiaole Shirley Liu, Jon C. Aster, Warren S. Pear

    Publicado 2014
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  11. 11
    Dynamic transcriptional reprogramming leads to immunotherapeutic vulnerabilities in myeloma

    Dynamic transcriptional reprogramming leads to immunotherapeutic vulnerabilities in myeloma por Julia Frede, Praveen Anand, Noori Sotudeh, Ricardo A. Pinto, Monica S. Nair, Hannah T. Stuart, Andrew J. Yee, Tushara Vijaykumar, Johannes M. Waldschmidt, Sayalee Potdar, Jake A. Kloeber, Antonis Kokkalis, Valeriya Dimitrova, Mason L. Mann, Jacob P. Laubach, Paul G. Richardson, Kenneth C. Anderson, Noopur Raje, Birgit Knoechel, Jens G. Lohr

    Publicado 2021
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  12. 12
    EWS-FLI1 Utilizes Divergent Chromatin Remodeling Mechanisms to Directly Activate or Repress Enhancer Elements in Ewing Sarcoma

    EWS-FLI1 Utilizes Divergent Chromatin Remodeling Mechanisms to Directly Activate or Repress Enhancer Elements in Ewing Sarcoma por Nicolò Riggi, Birgit Knoechel, Shawn Gillespie, Esther Rheinbay, Gaylor Boulay, Mario L. Suvà, Nikki E. Rossetti, Wannaporn E. Boonseng, Ozgur Oksuz, Edward Cook, Aurélie Formey, Anoop P. Patel, Melissa Gymrek, Vishal Thapar, Vikram Deshpande, David T. Ting, Francis J. Hornicek, G. Petur Nielsen, Ivan Stamenkovic, Martin J. Aryee, B Bernstein, Miguel N. Rivera

    Publicado 2014
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  13. 13
    An oncogenic MYB feedback loop drives alternate cell fates in adenoid cystic carcinoma

    An oncogenic MYB feedback loop drives alternate cell fates in adenoid cystic carcinoma por Yotam Drier, Matthew J. Cotton, Kaylyn E. Williamson, Shawn Gillespie, Russell J.H. Ryan, Michael Kluk, Christopher D. Carey, Scott J. Rodig, Lynette M. Sholl, Amir Afrogheh, William C. Faquin, Lurdes Queimado, Jun Qi, Michael J. Wick, Adel K. El‐Naggar, James E. Bradner, Christopher A. Moskaluk, Jon C. Aster, Birgit Knoechel, B Bernstein

    Publicado 2016
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  14. 14
    Discovery of Biomarkers Predictive of GSI Response in Triple-Negative Breast Cancer and Adenoid Cystic Carcinoma

    Discovery of Biomarkers Predictive of GSI Response in Triple-Negative Breast Cancer and Adenoid Cystic Carcinoma por Alexander Stoeck, Serguei Lejnine, Andrew Truong, Pan Li, Hongfang Wang, Chongzhi Zang, Jing Yuan, Chris Ware, John Maclean, Philip W. Garrett-Engele, Michael Kluk, Jason Laskey, Brian B. Haines, Christopher A. Moskaluk, Leigh Zawel, Stephen E. Fawell, Gary Gilliland, Theresa Zhang, Brandon E. Kremer, Birgit Knoechel, B Bernstein, Warren S. Pear, X. Shirley Liu, Jon C. Aster, Sriram Sathyanarayanan

    Publicado 2014
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  15. 15
    Genomic discovery and clonal tracking in multiple myeloma by cell-free DNA sequencing

    Genomic discovery and clonal tracking in multiple myeloma by cell-free DNA sequencing por Guangwu Guo, Noopur Raje, Charles Seifer, Jake A. Kloeber, Randi Isenhart, Gavin Ha, Andrew J. Yee, Elizabeth O’Donnell, Yu‐Tzu Tai, Paul G. Richardson, Giada Bianchi, Jacob P. Laubach, Diane Warren, Erica Gemme, Jordan Voisine, Julia Frede, Antonis Kokkalis, Huiyoung Yun, Valeriya Dimitrova, Tushara Vijaykumar, Matthew Meyerson, Nikhil C. Munshi, Kenneth C. Anderson, Birgit Knoechel, Jens G. Lohr

    Publicado 2018
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  16. 16
    Single-cell RNA-seq reveals developmental plasticity with coexisting oncogenic states and immune evasion programs in ETP-ALL

    Single-cell RNA-seq reveals developmental plasticity with coexisting oncogenic states and immune evasion programs in ETP-ALL por Praveen Anand, Amy Guillaumet-Adkins, Valeriya Dimitrova, Huiyoung Yun, Yotam Drier, Noori Sotudeh, Anna J. Rogers, Madhu M. Ouseph, Monica S. Nair, Sayalee Potdar, Randi Isenhart, Jake A. Kloeber, Tushara Vijaykumar, Leili Niu, Tiffaney L. Vincent, Guangwu Guo, Julia Frede, Marian H. Harris, Andrew E. Place, Lewis B. Silverman, David T. Teachey, Andrew A. Lane, Daniel J. DeAngelo, Jon C. Aster, B Bernstein, Jens G. Lohr, Birgit Knoechel

    Publicado 2020
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  17. 17
    Loss of metabolic fitness drives tumor resistance after CAR-NK cell therapy and can be overcome by cytokine engineering

    Loss of metabolic fitness drives tumor resistance after CAR-NK cell therapy and can be overcome by cytokine engineering por Li Li, Vakul Mohanty, Jinzhuang Dou, Yuefan Huang, Pinaki P. Banerjee, Qi Miao, Jens G. Lohr, Tushara Vijaykumar, Julia Frede, Birgit Knoechel, Luis Muniz-Feliciano, Tamara Laskowski, Shaoheng Liang, Judy S. Moyes, Vandana Nandivada, Rafet Başar, Mecit Kaplan, May Daher, Enli Liu, Ye Li, Sunil Acharya, Paul Lin, Mayra Shanley, Hind Rafei, David Marín, Stephan Mielke, Richard E. Champlin, Elizabeth J. Shpall, Ken Chen, Katayoun Rezvani

    Publicado 2023
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  18. 18
    An epigenetic mechanism of resistance to targeted therapy in T cell acute lymphoblastic leukemia

    An epigenetic mechanism of resistance to targeted therapy in T cell acute lymphoblastic leukemia por Birgit Knoechel, Justine E. Roderick, Kaylyn E. Williamson, Jiang Zhu, Jens G. Lohr, Matthew J. Cotton, Shawn Gillespie, Daniel E. Fernandez, Manching Ku, Hongfang Wang, Federica Piccioni, Serena J. Silver, Mohit Jain, Daniel S. Pearson, Michael Kluk, Christopher J. Ott, Leonard D. Shultz, Michael A. Brehm, Dale L. Greiner, Alejandro Gutiérrez, Kimberly Stegmaier, Andrew L. Kung, David E. Root, James E. Bradner, Jon C. Aster, Michelle A. Kelliher, B Bernstein

    Publicado 2014
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  19. 19
    PRC2 loss induces chemoresistance by repressing apoptosis in T cell acute lymphoblastic leukemia

    PRC2 loss induces chemoresistance by repressing apoptosis in T cell acute lymphoblastic leukemia por Ingrid M. Ariës, Kimberly Bodaar, Salmaan Karim, Triona Ní Chonghaile, Laura Hinze, Melissa Burns, Maren Pfirrmann, James Degar, Jack Landrigan, Sebastian T. Balbach, Sofie Peirs, Björn Menten, Randi Isenhart, Kristen E. Stevenson, Donna Neuberg, Meenakshi Devidas, Mignon L. Loh, Stephen P. Hunger, David T. Teachey, Karen R. Rabin, Stuart S. Winter, Kimberly P. Dunsmore, Brent L. Wood, Lewis B. Silverman, Stephen E. Sallan, Pieter Van Vlierberghe, Stuart H. Orkin, Birgit Knoechel, Anthony Letai, Alejandro Gutiérrez

    Publicado 2018
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  20. 20
    Gauging NOTCH1 Activation in Cancer Using Immunohistochemistry

    Gauging NOTCH1 Activation in Cancer Using Immunohistochemistry por Michael Kluk, Todd Ashworth, Hongfang Wang, Birgit Knoechel, Emily F. Mason, Elizabeth A. Morgan, David M. Dorfman, Geraldine Pinkus, Oliver Weigert, Jason L. Hornick, Lucian R. Chirieac, Michelle S. Hirsch, David J. Oh, Andrew P. South, Irene M. Leigh, Céline Pourreyron, Andrew Cassidy, Daniel J. DeAngelo, David M. Weinstock, Ian E. Krop, Deborah Dillon, Jane E. Brock, Alexander J. Lazar, Myron Peto, Raymond J. Cho, Alexander Stoeck, Brian B. Haines, Sriram Sathayanrayanan, Scott J. Rodig, Jon C. Aster

    Publicado 2013
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