Kết quả tìm kiếm - Benjamin Challis

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  1. 1
    Minireview: Human Obesity—Lessons from Monogenic Disorders

    Minireview: Human Obesity—Lessons from Monogenic Disorders Bằng Stephen O’Rahilly, I. Sadaf Farooqi, Giles S.H. Yeo, Benjamin Challis

    Được phát hành 2003
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  2. 2
    Quantitative Assessment of a Novel Device Designed for Patient-centric Sampling of Dried Plasma Using Targeted Proteomics

    Quantitative Assessment of a Novel Device Designed for Patient-centric Sampling of Dried Plasma Using Targeted Proteomics Bằng Andreas Hober, Marcus Henricsson, Tim Ruckh, Pia Davidsson, Benjamin Challis, Tasso Miliotis

    Được phát hành 2025
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  3. 3
    Machine Learning Enabled Non-invasive Diagnosis of Nonalcoholic Fatty Liver Disease and Assessment of Abdominal Fat from MRI Data

    Machine Learning Enabled Non-invasive Diagnosis of Nonalcoholic Fatty Liver Disease and Assessment of Abdominal Fat from MRI Data Bằng Arvind Pillai, Kamen Bliznashki, Emmette R. Hutchison, Chanchal Kumar, Benjamin Challis, Mishal Patel

    Được phát hành 2022
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  4. 4
    Proopiomelanocortin and Energy Balance: Insights from Human and Murine Genetics

    Proopiomelanocortin and Energy Balance: Insights from Human and Murine Genetics Bằng Anthony P. Coll, I. Sadaf Farooqi, Benjamin Challis, Giles S.H. Yeo, Stephen O’Rahilly

    Được phát hành 2004
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  5. 5
    Mutations in the human melanocortin-4 receptor gene associated with severe familial obesity disrupts receptor function through multiple molecular mechanisms

    Mutations in the human melanocortin-4 receptor gene associated with severe familial obesity disrupts receptor function through multiple molecular mechanisms Bằng Giles S.H. Yeo, Emma Lank, I. Sadaf Farooqi, Julia M. Keogh, Benjamin Challis, Stephen O’Rahilly

    Được phát hành 2003
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  6. 6
    Peptidomic analysis of endogenous plasma peptides from patients with pancreatic neuroendocrine tumours

    Peptidomic analysis of endogenous plasma peptides from patients with pancreatic neuroendocrine tumours Bằng Richard G. Kay, Benjamin Challis, Ruth Casey, Geoffrey Roberts, Claire L. Meek, Frank Reimann, Fiona M. Gribble

    Được phát hành 2018
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  7. 7
    Safety and Efficacy of Novel Incretin Co-agonist Cotadutide in Biopsy-proven Noncirrhotic MASH With Fibrosis

    Safety and Efficacy of Novel Incretin Co-agonist Cotadutide in Biopsy-proven Noncirrhotic MASH With Fibrosis Bằng Sudha S. Shankar, Samuel J. Daniels, Darren Robertson, Janeli Sarv, José Sánchez, Debra Carter, Lutz Jermutus, Benjamin Challis, Arun J. Sanyal

    Được phát hành 2024
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  8. 8
    A review of the tumour spectrum of germline succinate dehydrogenase gene mutations: Beyond phaeochromocytoma and paraganglioma

    A review of the tumour spectrum of germline succinate dehydrogenase gene mutations: Beyond phaeochromocytoma and paraganglioma Bằng James MacFarlane, Keat Cheah Seong, Chad Bisambar, Basetti Madhu, Kieren Allinson, Alison Marker, Anne Y. Warren, Soo‐Mi Park, Olivier Giger, Benjamin Challis, Eamonn R. Maher, Ruth Casey

    Được phát hành 2020
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  9. 9
    Effects of protein-coding variants on blood metabolite measurements and clinical biomarkers in the UK Biobank

    Effects of protein-coding variants on blood metabolite measurements and clinical biomarkers in the UK Biobank Bằng Abhishek Nag, Ryan S. Dhindsa, Lawrence Middleton, Xiao Jiang, Dimitrios Vitsios, Eleanor M. Wigmore, Erik L. Allman, Anna Reznichenko, Keren Carss, Katherine R. Smith, Quanli Wang, Benjamin Challis, Dirk S. Paul, Andrew R. Harper, Slavé Petrovski

    Được phát hành 2023
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  10. 10
    A missense mutation disrupting a dibasic prohormone processing site in pro-opiomelanocortin (POMC) increases susceptibility to early-onset obesity through a novel molecular mechanism

    A missense mutation disrupting a dibasic prohormone processing site in pro-opiomelanocortin (POMC) increases susceptibility to early-onset obesity through a novel molecular mechani... Bằng Benjamin Challis, Lynn E. Pritchard, John W.M. Creemers, Jérôme Delplanque, Julia M. Keogh, Jian’an Luan, Nicholas J. Wareham, Giles S.H. Yeo, Sumit Bhattacharyya, Philippe Froguel, Anne White, I. Sadaf Farooqi, Stephen O’Rahilly

    Được phát hành 2002
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  11. 11
    Inhibition of Interleukin-33 to Reduce Glomerular Endothelial Inflammation in Diabetic Kidney Disease

    Inhibition of Interleukin-33 to Reduce Glomerular Endothelial Inflammation in Diabetic Kidney Disease Bằng Alexis Hofherr, Elena Liarte Marin, Barbara Musiał, Asha Seth, Tim Slidel, James Conway, David Baker, Pernille Hansen, Benjamin Challis, Stefano Bartesaghi, Maria Bhat, Roberto Pecoits–Filho, Tu Xiao, Viknesh Selvarajah, Kevin Woollard, Hiddo J.L. Heerspink

    Được phát hành 2024
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  12. 12
    #5413 FRONTIER-1: A PHASE 2B STUDY OF IL-33 BLOCKADE IN DIABETIC KIDNEY DISEASE

    #5413 FRONTIER-1: A PHASE 2B STUDY OF IL-33 BLOCKADE IN DIABETIC KIDNEY DISEASE Bằng Elena Liarte Marin, Barbara Musiał, Asha Seth, Timothy Slidel, James Conway, David H. Baker, Pernille Laerkegaard Hansen, Benjamin Challis, Maria Bhat, Stefano Bartesaghi, Roberto Pecoits–Filho, Tu Xiao, Viknesh Selvarajah, Kevin Woollard, Hiddo J.L. Heerspink, Alexis Hofherr

    Được phát hành 2023
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  13. 13
    An Activating Mutation of <i>AKT2</i> and Human Hypoglycemia

    An Activating Mutation of <i>AKT2</i> and Human Hypoglycemia Bằng Khalid Hussain, Benjamin Challis, Nuno Rocha, Felicity Payne, Marina Minic, Alastair Thompson, Allan Daly, Clare L. Scott, Jeffrey R. Harris, B. J. L. Smillie, David B. Savage, Uma Ramaswami, Pascale de Lonlay, Stephen O’Rahilly, Inês Barroso, Robert K. Semple

    Được phát hành 2011
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  14. 14
    Mice lacking pro-opiomelanocortin are sensitive to high-fat feeding but respond normally to the acute anorectic effects of peptide-YY <sub>3-36</sub>

    Mice lacking pro-opiomelanocortin are sensitive to high-fat feeding but respond normally to the acute anorectic effects of peptide-YY <sub>3-36</sub> Bằng Benjamin Challis, Anthony P. Coll, Giles S.H. Yeo, Scarlett B. Pinnock, Suzanne L. Dickson, Rosemary R. Thresher, John B. Dixon, Dirk Zahn, Justin J. Rochford, Anne White, R. L. Oliver, G. W. M. Millington, Samuel Aparício, William H Colledge, A. P. Russ, Mark Carlton, Stephen O’Rahilly

    Được phát hành 2004
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  15. 15
    Influences of rare protein-coding genetic variants on the human plasma proteome in 50,829 UK Biobank participants

    Influences of rare protein-coding genetic variants on the human plasma proteome in 50,829 UK Biobank participants Bằng Ryan S. Dhindsa, Oliver S. Burren, Benjamin B. Sun, Bram P. Prins, Dorota Matelska, Eleanor Wheeler, Jonathan Mitchell, Erin Oerton, Ventzislava A. Hristova, Katherine R. Smith, Keren Carss, Sebastian Wasilewski, Andrew R. Harper, Dirk S. Paul, Margarete A. Fabre, Heiko Runz, Coralie Viollet, Benjamin Challis, Adam Platt, Dimitrios Vitsios, Euan A. Ashley, Christopher D. Whelan, Menelas N. Pangalos, Quanli Wang, Slavé Petrovski

    Được phát hành 2022
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  16. 16
    CT Characteristics of Pheochromocytoma: Relevance for the Evaluation of Adrenal Incidentaloma

    CT Characteristics of Pheochromocytoma: Relevance for the Evaluation of Adrenal Incidentaloma Bằng Letizia Canu, Janna A W Van Hemert, Michiel N. Kerstens, Robert P. Hartman, Aakanksha Khanna, Ivana Kraljević, Darko Kaštelan, Corin Badiu, Urszula Ambroziak, Antoine Tabarin, Magalie Haissaguerre, Edward Buitenwerf, Anneke Visser, Massimo Mannelli, Wiebke Arlt, Vasileios Chortis, Isabelle Bourdeau, Nadia Gagnon, Marie Buchy, Françoise Borson‐Chazot, Timo Deutschbein, Martin Faßnacht, Alicja Hubalewska‐Dydejczyk, Marcin Motyka, Ewelina Rzepka, Ruth Casey, Benjamin Challis, Marcus Quinkler, Laurent Vroonen, Ariadni Spyroglou, Felix Beuschlein, Cristina Lamas, William F. Young, Irina Bancos, Henri Timmers

    Được phát hành 2018
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  17. 17
    Rare variant contribution to human disease in 281,104 UK Biobank exomes

    Rare variant contribution to human disease in 281,104 UK Biobank exomes Bằng Quanli Wang, Ryan S. Dhindsa, Keren Carss, Andrew R. Harper, Abhishek Nag, Ioanna Tachmazidou, Dimitrios Vitsios, Sri V. V. Deevi, Alex Mackay, Daniel Muthas, Michael Hühn, Susan J. Monkley, Henric Olsson, Bastian R. Angermann, Ronen Artzi, Carl Barrett, Maria G. Belvisi, Mohammad Bohlooly‐Y, Oliver S. Burren, Lisa Buvall, Benjamin Challis, Sophia Cameron‐Christie, E. Suzanne Cohen, Andrew Davis, Regina Fritsche Danielson, Brian Dougherty, Benjamin Georgi, Zara Ghazoui, Pernille Hansen, Fengyuan Hu, Magda Jeznach, Xiao Jiang, Chanchal Kumar, Zhongwu Lai, Glenda Lassi, Samuel H. Lewis, Bolan Linghu, Kieren Lythgow, Peter Maccallum, Carla Martins, Athena Matakidou, Erik Michaëlsson, Sven Moosmang, Sean M. O’Dell, Yoichiro Ohne, Joel Okae, Amanda O’Neill, Dirk S. Paul, Anna Reznichenko, Michael Snowden, Anna Walentinsson, Jorge Zeron, Menelas N. Pangalos, Sebastian Wasilewski, Katherine R. Smith, Ruth March, Adam Platt, Carolina Haefliger, Slavé Petrovski

    Được phát hành 2021
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  18. 18
    Hematopoietic mosaic chromosomal alterations increase the risk for diverse types of infection

    Hematopoietic mosaic chromosomal alterations increase the risk for diverse types of infection Bằng Seyedeh M. Zekavat, Shu‐Hong Lin, Alexander G. Bick, Aoxing Liu, Kaavya Paruchuri, Chen Wang, Md Mesbah Uddin, Yixuan Ye, Zhaolong Yu, Xiaoxi Liu, Yoichiro Kamatani, Romit Bhattacharya, James P. Pirruccello, Akhil Pampana, Po‐Ru Loh, Puja Kohli, Steven A. McCarroll, Krzysztof Kiryluk, Benjamin M. Neale, Iuliana Ionita‐Laza, Eric A. Engels, Derek W. Brown, Jordan W. Smoller, Robert C. Green, Elizabeth W. Karlson, Matthew S. Lebo, Patrick T. Ellinor, Scott T. Weiss, Mark J. Daly, Satoshi Koyama, Kaoru Ito, Yukihide Momozawa, Koichi Matsuda, Yuji Yamanashi, Yoichi Furukawa, Takayuki Morisaki, Yoshinori Murakami, Kaori Muto, Akiko Nagai, Wataru Obara, Ken Yamaji, Kazuhisa Takahashi, Satoshi Asai, Yasuo Takahashi, Takao Suzuki, Nobuaki Sinozaki, Hiroki Yamaguchi, Shiro Minami, Shigeo Murayama, Kozo Yoshimori, Satoshi Nagayama, Daisuke Obata, Masahiko Higashiyama, Akihide Masumoto, Yukihiro Koretsune, Aarno Palotie, Adam Ziemann, Adele A. Mitchell, Adriana Huertas‐Vázquez, Aino Salminen, Airi Jussila, Aki S. Havulinna, Alex Mackay, Ali Abbasi, Amanda Elliott, Amy L. Cole, Anastasia Shcherban, Anders Mälarstig, Andrea Ganna, Andrey Loboda, Anna Podgornaia, Anne Lehtonen, Anne Pitkäranta, Anne M. Remes, Annika Auranen, Antti Hakanen, Antti Palomäki, Anu Jalanko, Anu Loukola, Aparna Chhibber, Apinya Lertratanakul, Arto Lehistö, Graham J. Mann, Åsa K. Hedman, Audrey Y. Chu, Aviv Madar, Awaisa Ghazal, Benjamin Challis, Benjamin B. Sun, Beryl B. Cummings, Bridget Riley‐Gillis, Caroline S. Fox, Chia‐Yen Chen, Clarence Wang, Clément Chatelain, Daniel Gordin, Danjuma Quarless, Danny Oh, David F. Choy, David A. Close

    Được phát hành 2021
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  19. 19
    Narcolepsy risk loci outline role of T cell autoimmunity and infectious triggers in narcolepsy

    Narcolepsy risk loci outline role of T cell autoimmunity and infectious triggers in narcolepsy Bằng Hanna M. Ollila, Eilon Sharon, Ling Lin, Nasa Sinnott-Armstrong, Aditya Ambati, Selina Yogeshwar, Ryan P. Hillary, Otto Jolanki, Juliette Faraco, Mali Einen, Guo Luo, Jing Zhang, Fang Han, Han Yan, Xiao Song Dong, Jing Li, Jun Zhang, Seung‐Chul Hong, Tae Won Kim, Yves Dauvilliers, Lucie Barateau, Gert Jan Lammers, Rolf Fronczek, Geert Mayer, Joan Santamaría, Isabelle Arnulf, Stine Knudsen, May Kristin Lyamouri Bredahl, Per Medbøe Thorsby, Giuseppe Plazzi, Fabio Pizza, Monica Moresco, Catherine Crowe, Stephen K. Van Den Eeden, Michel Lecendreux, Patrice Bourgin, Takashi Kanbayashi, F Martínez-Orozco, Rosa Peraita‐Adrados, Antonio Benetó, Jacques Montplaisir, Alex Désautels, Yu‐Shu Huang, Thomas D. Als, Adam Ziemann, Ali Abbasi, Anne Lehtonen, Apinya Lertratanakul, Bridget Riley‐Gillis, Fedik Rahimov, Howard J. Jacob, Jeffrey F. Waring, Mengzhen Liu, Nizar Smaoui, Relja Popovic, Adam Platt, Athena Matakidou, Benjamin Challis, Dirk S. Paul, Glenda Lassi, Ioanna Tachmazidou, Antti Hakanen, Johanna Schleutker, Nina Pitkänen, Perttu Terho, Petri Virolainen, Arto Mannermaa, Veli‐Matti Kosma, Chia‐Yen Chen, Heiko Runz, Sally John, Sanni Lahdenperä, Stephanie Loomis, Susan Eaton, George Okafo, Heli Salminen‐Mankonen, Marc Jung, Nathan Lawless, Zhihao Ding, Joseph Maranville, Marla Hochfeld, Robert Plenge, Shameek Biswas, Masahiro Kanai, Mutaamba Maasha, Wei Zhou, Outi Tuovila, Raimo Pakkanen, Jari A. Laukkanen, Teijo Kuopio, Kristiina Aittomäki, Antti Mäkitie, Natalia Pujol, Triin Laisk, Katriina Aalto‐Setälä, Johanna Mäkelä, Marco Hautalahti, Sarah Smith, Tom Southerington, Eeva Kangasniemi

    Được phát hành 2023
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  20. 20
    Rare variant associations with plasma protein levels in the UK Biobank

    Rare variant associations with plasma protein levels in the UK Biobank Bằng Ryan S. Dhindsa, Oliver S. Burren, Benjamin B. Sun, Bram P. Prins, Dorota Matelska, Eleanor Wheeler, Jonathan Mitchell, Erin Oerton, Ventzislava A. Hristova, Katherine R. Smith, Keren Carss, Sebastian Wasilewski, Andrew R. Harper, Dirk S. Paul, Margarete A. Fabre, Heiko Runz, Coralie Viollet, Benjamin Challis, Adam Platt, Rasmus Ågren, Lauren Anderson-Dring, Santosh S. Atanur, David H. Baker, Carl Barrett, Maria G. Belvisi, Mohammad Bohlooly‐Y, Lisa Buvall, Niedzica Camacho, Lisa H. Cazares, Sophia Cameron‐Christie, Morris Chen, E. Suzanne Cohen, Regina Fritsche Danielson, Shikta Das, Andrew Davis, Sri Vishnu Vardhan Deevi, Wei Ding, Brian Dougherty, Zammy Fairhurst-Hunter, Manik Garg, Benjamin Georgi, Carmen Guerrero Rangel, Carolina Haefliger, Mårten Hammar, Richard N. Hanna, Pernille Hansen, Jennifer Harrow, Ian Henry, Sonja Hess, Ben Hollis, Fengyuan Hu, Xiao Jiang, Kousik Kundu, Zhongwu Lai, Mark Lal, Glenda Lassi, Yupu Liang, Margarida Lopes, Kieren Lythgow, Stewart MacArthur, Meeta Maisuria-Armer, Ruth March, Carla Martins, Karyn Mégy, Robert Menzies, Erik Michaëlsson, Fiona K. Middleton, Bill Mowrey, Daniel Muthas, Abhishek Nag, Sean M. O’Dell, Yoichiro Ohne, Henric Olsson, Amanda O’Neill, Kristoffer Ostridge, Benjamin Pullman, William Rae, Arwa Bin Raies, Anna Reznichenko, Xavier Romero Ros, Maria Ryaboshapkina, Hitesh J. Sanganee, Ben S. Sidders, Mike Snowden, Stasa Stankovic, Helen Stevens, Ioanna Tachmazidou, Haeyam Taiy, Lifeng Tian, Christina Underwood, Anna Walentinsson, Qing‐Dong Wang, Ahmet Zehir, Zoe Zou, Dimitrios Vitsios, Euan A. Ashley, Christopher D. Whelan, Menelas N. Pangalos, Quanli Wang, Slavé Petrovski

    Được phát hành 2023
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