Resultats de la cerca - Beatrice Darimont

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  1. 1
    2.0 å structure of indole-3-glycerol phosphate synthase from the hyperthermophile Sulfolobus solfataricus: possible determinants of protein stability

    2.0 å structure of indole-3-glycerol phosphate synthase from the hyperthermophile Sulfolobus solfataricus: possible determinants of protein stability per Michael Hennig, Beatrice Darimont, Reinhard Sterner, Kasper Kirschner, Johan N. Jansonius

    Publicat 1995
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  2. 2
    A Conformational Switch in the Ligand-binding Domain Regulates the Dependence of the Glucocorticoid Receptor on Hsp90

    A Conformational Switch in the Ligand-binding Domain Regulates the Dependence of the Glucocorticoid Receptor on Hsp90 per Derek Ricketson, Ute Hostick, Lincan Fang, Keith R. Yamamoto, Beatrice Darimont

    Publicat 2007
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  3. 3
    An Additional Region of Coactivator GRIP1 Required for Interaction with the Hormone-binding Domains of a Subset of Nuclear Receptors

    An Additional Region of Coactivator GRIP1 Required for Interaction with the Hormone-binding Domains of a Subset of Nuclear Receptors per Heng Hong, Beatrice Darimont, Han Ma, Lan Yang, Keith R. Yamamoto, Michael R. Stallcup

    Publicat 1999
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  4. 4
    Phosphorylation of the Nuclear Receptor SF-1 Modulates Cofactor Recruitment

    Phosphorylation of the Nuclear Receptor SF-1 Modulates Cofactor Recruitment per Gary D. Hammer, Ирина Николаевна Крылова, Yixian Zhang, Beatrice Darimont, Kimberly L. Simpson, Nancy L. Weigel, Holly A. Ingraham

    Publicat 1999
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  5. 5
    Structure and specificity of nuclear receptor–coactivator interactions

    Structure and specificity of nuclear receptor–coactivator interactions per Beatrice Darimont, Richard Wagner, James W. Apriletti, Michael R. Stallcup, Peter J. Kushner, John D. Baxter, Robert J. Fletterick, Keith R. Yamamoto

    Publicat 1998
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  6. 6
    Target-specific utilization of transcriptional regulatory surfaces by the glucocorticoid receptor

    Target-specific utilization of transcriptional regulatory surfaces by the glucocorticoid receptor per Inez Rogatsky, Jen-Chywan Wang, Mika K. Derynck, Daisuke Nonaka, Daniel Khodabakhsh, Christopher M. Haqq, Beatrice Darimont, Michael J. Garabedian, Keith R. Yamamoto

    Publicat 2003
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  7. 7
    A Clinically Relevant Androgen Receptor Mutation Confers Resistance to Second-Generation Antiandrogens Enzalutamide and ARN-509

    A Clinically Relevant Androgen Receptor Mutation Confers Resistance to Second-Generation Antiandrogens Enzalutamide and ARN-509 per James D. Joseph, Nhin Lu, Jing Qian, John Sensintaffar, Gang Shao, Dan Brigham, Michael Moon, Edna Chow Maneval, Isan Chen, Beatrice Darimont, Jeffrey H. Hager

    Publicat 2013
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  8. 8
    A C-Terminal Inhibitory Domain Controls the Activity of p63 by an Intramolecular Mechanism

    A C-Terminal Inhibitory Domain Controls the Activity of p63 by an Intramolecular Mechanism per Zach Serber, Helen C. Lai, Annie Yang, Horng D. Ou, Martina Sigal, Alexander E. Kelly, Beatrice Darimont, Pascal H. G. Duijf, Hans van Bokhoven, Frank McKeon, Volker Dötsch

    Publicat 2002
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  9. 9
    Targeted tissue delivery of RNA therapeutics using antibody–oligonucleotide conjugates (AOCs)

    Targeted tissue delivery of RNA therapeutics using antibody–oligonucleotide conjugates (AOCs) per Barbora Malecová, Rob S. Burke, Michael A. Cochran, Michael D Hood, Rachel Johns, Philip Kovach, Venkata Ramana Doppalapudi, Gulin Erdogan, J Danny Arias, Beatrice Darimont, Christopher Miller, Hanhua Huang, Andrew J. Geall, Husam S. Younis, Arthur A. Levin

    Publicat 2023
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  10. 10
    Maximizing ER-α Degradation Maximizes Activity in a Tamoxifen-Resistant Breast Cancer Model: Identification of GDC-0927

    Maximizing ER-α Degradation Maximizes Activity in a Tamoxifen-Resistant Breast Cancer Model: Identification of GDC-0927 per Mehmet Kahraman, Steven P. Govek, Johnny Nagasawa, Andiliy Lai, Céline Bonnefous, Karensa Douglas, John Sensintaffar, Nhin Liu, KyoungJin Lee, Anna Aparicio, Josh Kaufman, Jing Qian, Gang Shao, Rene Prudente, James D. Joseph, Beatrice Darimont, Daniel Brigham, Richard A. Heyman, Peter J. Rix, Jeffrey H. Hager, Nicholas D. Smith

    Publicat 2018
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  11. 11
    ARN-509: A Novel Antiandrogen for Prostate Cancer Treatment

    ARN-509: A Novel Antiandrogen for Prostate Cancer Treatment per Nicola J. Clegg, John Wongvipat, James D. Joseph, Chris Tran, Samedy Ouk, Anna Dilhas, Yu Chen, Kate Grillot, Eric D. Bischoff, Ling Cai, Anna Aparicio, Steven Dorow, Vivek Arora, Gang Shao, Jing Qian, Hong Zhao, Guangbin Yang, Chunyan Cao, John Sensintaffar, Teresa Wasielewska, Mark R. Herbert, Céline Bonnefous, Beatrice Darimont, Howard I. Scher, Peter Smith‐Jones, Mark Klang, Nicholas D. Smith, Elisa de Stanchina, Nian Wu, Ouathek Ouerfelli, Peter J. Rix, Richard A. Heyman, Michael E. Jung, Charles L. Sawyers, Jeffrey H. Hager

    Publicat 2012
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  12. 12
    The selective estrogen receptor downregulator GDC-0810 is efficacious in diverse models of ER+ breast cancer

    The selective estrogen receptor downregulator GDC-0810 is efficacious in diverse models of ER+ breast cancer per James D. Joseph, Beatrice Darimont, Wei Zhou, Alfonso Arrazate, Amy Young, Ellen Ingalla, Kimberly Walter, Robert A. Blake, Jim Nonomiya, Zhengyu Guan, Lorna Kategaya, Steven P. Govek, Andiliy Lai, Mehmet Kahraman, Dan Brigham, John Sensintaffar, Nhin Lu, Gang Shao, Jing Qian, Kate Grillot, Michael Moon, Rene Prudente, Eric D. Bischoff, Kyoung-Jin Lee, Céline Bonnefous, Karensa Douglas, Jackaline D Julien, Johnny Nagasawa, Anna Aparicio, Josh Kaufman, Benjamin Haley, Jennifer M. Giltnane, Ingrid E. Wertz, Mark R. Lackner, Michelle Nannini, Deepak Sampath, Luis J. Schwarz, Henry Charles Manning, Mohammed Noor Tantawy, Carlos L. Arteaga, Richard A. Heyman, Peter J. Rix, Lori S. Friedman, Nicholas D. Smith, Ciara Metcalfe, Jeffrey H. Hager

    Publicat 2016
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