Resultados de procura - Barak Rotblat

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  1. 1
    How does mTOR sense glucose starvation? AMPK is the usual suspect

    How does mTOR sense glucose starvation? AMPK is the usual suspect por Gabriel Leprivier, Barak Rotblat

    Publicado 2020
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  2. 2
    NRF2 and p53: Januses in cancer?

    NRF2 and p53: Januses in cancer? por Barak Rotblat, Gerry Melino, Richard A. Knight

    Publicado 2012
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  3. 3
    Screening for E3-Ubiquitin ligase inhibitors: challenges and opportunities

    Screening for E3-Ubiquitin ligase inhibitors: challenges and opportunities por Vivien Landré, Barak Rotblat, Sonia Melino, Francesca Bernassola, Gerry Melino

    Publicado 2014
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  4. 4
    Galectin-1 Is a Novel Structural Component and a Major Regulator of H-Ras Nanoclusters

    Galectin-1 Is a Novel Structural Component and a Major Regulator of H-Ras Nanoclusters por Liron Belanis, Sarah J. Plowman, Barak Rotblat, John F. Hancock, Yoel Kloog

    Publicado 2008
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  5. 5
    Anti-oxidative stress response genes: bioinformatic analysis of their expression and relevance in multiple cancers

    Anti-oxidative stress response genes: bioinformatic analysis of their expression and relevance in multiple cancers por Barak Rotblat, Thomas G. P. Grünewald, Gabriel Leprivier, Gerry Melino, Richard A. Knight

    Publicado 2013
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  6. 6
    Galectin-1(L11A) Predicted from a Computed Galectin-1 Farnesyl-Binding Pocket Selectively Inhibits Ras-GTP

    Galectin-1(L11A) Predicted from a Computed Galectin-1 Farnesyl-Binding Pocket Selectively Inhibits Ras-GTP por Barak Rotblat, Hagit Niv, Sabine André, Herbert Kaltner, Hans‐Joachim Gabius, Yoel Kloog

    Publicado 2004
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  7. 7
    K-Ras Nanoclustering Is Subverted by Overexpression of the Scaffold Protein Galectin-3

    K-Ras Nanoclustering Is Subverted by Overexpression of the Scaffold Protein Galectin-3 por Ruby Shalom‐Feuerstein, Sarah J. Plowman, Barak Rotblat, Nicholas Ariotti, Tianhai Tian, John F. Hancock, Yoel Kloog

    Publicado 2008
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  8. 8
    Three Separable Domains Regulate GTP-Dependent Association of H-ras with the Plasma Membrane

    Three Separable Domains Regulate GTP-Dependent Association of H-ras with the Plasma Membrane por Barak Rotblat, Ian A. Prior, Cornelia Muncke, Robert G. Parton, Yoel Kloog, Yoav I. Henis, John F. Hancock

    Publicado 2004
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  9. 9
    IGF1R upregulation confers resistance to isoform-specific inhibitors of PI3K in PIK3CA-driven ovarian cancer

    IGF1R upregulation confers resistance to isoform-specific inhibitors of PI3K in PIK3CA-driven ovarian cancer por Jonathan Zorea, Manu Prasad, Limor Cohen, Nan Li, Roman Schefzik, Susmita Ghosh, Barak Rotblat, Benedikt Brors, Moshe Elkabets

    Publicado 2018
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  10. 10
    The lncRNA TP73-AS1 is linked to aggressiveness in glioblastoma and promotes temozolomide resistance in glioblastoma cancer stem cells

    The lncRNA TP73-AS1 is linked to aggressiveness in glioblastoma and promotes temozolomide resistance in glioblastoma cancer stem cells por Gal Mazor, Liron Levin, Daniel Picard, Ulvi Ahmadov, Helena Carén, Arndt Borkhardt, Guido Reifenberger, Gabriel Leprivier, Marc Remke, Barak Rotblat

    Publicado 2019
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  11. 11
    Eukaryotic initiation factor 4E-binding protein 1 (4E-BP1): a master regulator of mRNA translation involved in tumorigenesis

    Eukaryotic initiation factor 4E-binding protein 1 (4E-BP1): a master regulator of mRNA translation involved in tumorigenesis por Julian Musa, Martin F. Orth, Marlene Dallmayer, Michaela C. Baldauf, Catia Lo Pardo, Barak Rotblat, Thomas Kirchner, Gabriel Leprivier, Thomas G. P. Grünewald

    Publicado 2016
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  12. 12
    High throughput screening for inhibitors of the HECT ubiquitin E3 ligase ITCH identifies antidepressant drugs as regulators of autophagy

    High throughput screening for inhibitors of the HECT ubiquitin E3 ligase ITCH identifies antidepressant drugs as regulators of autophagy por Mario Rossi, Barak Rotblat, Keith H. Ansell, Ivano Amelio, Michele Caraglia, Gabriella Misso, Francesca Bernassola, Claudio N. Cavasotto, Richard A. Knight, Aaron Ciechanover, Gerry Melino

    Publicado 2014
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  13. 13
    Repression of AXL expression by AP-1/JNK blockage overcomes resistance to PI3Ka therapy

    Repression of AXL expression by AP-1/JNK blockage overcomes resistance to PI3Ka therapy por Mai Badarni, Manu Prasad, Noa Balaban, Jonathan Zorea, Ksenia M. Yegodayev, Ben‐Zion Joshua, Anat Bahat Dinur, Reidar Grénman, Barak Rotblat, Limor Cohen, Moshe Elkabets

    Publicado 2019
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  14. 14
    Individual Palmitoyl Residues Serve Distinct Roles in H-Ras Trafficking, Microlocalization, and Signaling

    Individual Palmitoyl Residues Serve Distinct Roles in H-Ras Trafficking, Microlocalization, and Signaling por Sandrine Roy, Sarah J. Plowman, Barak Rotblat, Ian A. Prior, Cornelia Muncke, Sarah A. Grainger, Robert G. Parton, Yoav I. Henis, Yoel Kloog, John F. Hancock

    Publicado 2005
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  15. 15
    Hace1 controls ROS generation of vertebrate Rac1-dependent NADPH oxidase complexes

    Hace1 controls ROS generation of vertebrate Rac1-dependent NADPH oxidase complexes por Mads Daugaard, Roberto Nitsch, Babak Razaghi, Lindsay McDonald, Ameer Jarrar, Stéphanie Torrino, Sonia Castillo‐Lluva, Barak Rotblat, Liheng Li, Angeliki Malliri, Emmanuel Lemichez, Amel Mettouchi, Jason N. Berman, Josef Penninger, Poul H. Sorensen

    Publicado 2013
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  16. 16
    HACE1 reduces oxidative stress and mutant Huntingtin toxicity by promoting the NRF2 response

    HACE1 reduces oxidative stress and mutant Huntingtin toxicity by promoting the NRF2 response por Barak Rotblat, Amber L. Southwell, Dagmar E. Ehrnhoefer, Niels H. Skotte, Martina Metzler, Sonia Franciosi, Gabriel Leprivier, Syam Prakash Somasekharan, Adi Barokas, Yu Deng, Tiffany Tang, Joan Mathers, Naniye Mallı Cetinbas, Mads Daugaard, Brian Kwok, Liheng Li, Christopher J. Carnie, Dieter Fink, Roberto Nitsch, Jason D. Galpin, Christopher A. Ahern, Gerry Melino, Josef Penninger, Michael R. Hayden, Poul H. Sorensen

    Publicado 2014
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  17. 17
    MEK1/2 inhibition transiently alters the tumor immune microenvironment to enhance immunotherapy efficacy against head and neck cancer

    MEK1/2 inhibition transiently alters the tumor immune microenvironment to enhance immunotherapy efficacy against head and neck cancer por Manu Prasad, Jonathan Zorea, Sankar Jagadeeshan, Avital Beeri. Shnerb, Sooraj Mathukkada, Jebrane Bouaoud, Lucas Michon, Ofra Novoplansky, Mai Badarni, Limor Cohen, Ksenia M. Yegodayev, Sapir Tzadok, Barak Rotblat, Libor Brezina, Andreas Möck, Andy Karabajakian, Jérôme Fayette, Idan Cohen, Tomer Cooks, Irit Allon, Orr Dimitstein, Ben‐Zion Joshua, Dexin Kong, Elena Voronov, Maurizio Scaltriti, Yaron Carmi, Cristina Conde‐López, Jochen Heß, Ina Kurth, Luc G.T. Morris, Pierre Saintigny, Moshe Elkabets

    Publicado 2022
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  18. 18
    mTORC1 regulates cell survival under glucose starvation through 4EBP1/2-mediated translational reprogramming of fatty acid metabolism

    mTORC1 regulates cell survival under glucose starvation through 4EBP1/2-mediated translational reprogramming of fatty acid metabolism por Tal Levy, Kai Voeltzke, Laura Hruby, Khawla Alasad, Zuelal Bas, Marteinn T. Snaebjornsson, Ran Marciano, Katerina Scharov, Mélanie Planque, Kim Vriens, Stefan Christen, Cornelius M. Funk, Christina Hassiepen, Alisa Kahler, Beate Heider, Daniel Picard, Jonathan Lim, Anja Stefanski, Katja Bendrin, Andres Vargas‐Toscano, Ulf D. Kahlert, Kai Stühler, Marc Remke, Moshe Elkabets, Thomas G. P. Grünewald, Andreas S. Reichert, Sarah‐Maria Fendt, Almut Schulze, Guido Reifenberger, Barak Rotblat, Gabriel Leprivier

    Publicado 2024
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  19. 19
    Cooperation of cancer drivers with regulatory germline variants shapes clinical outcomes

    Cooperation of cancer drivers with regulatory germline variants shapes clinical outcomes por Julian Musa, Florencia Cidre‐Aranaz, Marie-Ming Aynaud, Martin F. Orth, Maximilian M. L. Knott, Olivier Mirabeau, Gal Mazor, Mor Varon, Tilman L. B. Hölting, Sandrine Grossetête, Moritz Gartlgruber, Didier Surdez, Julia S. Gerke, Shunya Ohmura, Aruna Marchetto, Marlene Dallmayer, Michaela C. Baldauf, Stefanie Stein, Giuseppina Sannino, Jing Li, Laura Romero‐Pérez, Frank Westermann, Wolfgang Hartmann, Uta Dirksen, Melissa Gymrek, Nathaniel D. Anderson, Adam Shlien, Barak Rotblat, Thomas Kirchner, Olivier Delattre, Thomas G. P. Grünewald

    Publicado 2019
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  20. 20
    The eEF2 Kinase Confers Resistance to Nutrient Deprivation by Blocking Translation Elongation

    The eEF2 Kinase Confers Resistance to Nutrient Deprivation by Blocking Translation Elongation por Gabriel Leprivier, Marc Remke, Barak Rotblat, Adrian M. Dubuc, Abigail-Rachele F. Mateo, Marcel Kool, Sameer Agnihotri, Amal M. El-Naggar, Bin Yu, Syam Prakash Somasekharan, Brandon Faubert, Gaëlle Bridon, Cristina E. Tognon, Joan Mathers, Ryan M. Thomas, Amy Li, Adi Barokas, Brian Kwok, Mary Bowden, Stephanie Smith, Xiaochong Wu, Andrey Korshunov, Thomas Hielscher, Paul A. Northcott, Jason D. Galpin, Christopher A. Ahern, Ye Wang, Martin G. McCabe, V. Peter Collins, Russell G. Jones, Michaël Pollak, Olivier Delattre, Martin Gleave, Eric Jan, Stefan M. Pfister, Christopher G. Proud, W. Brent Derry, Michael D. Taylor, Poul H. Sorensen

    Publicado 2013
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