Search Results - Barak Rotblat

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  1. 1
    How does mTOR sense glucose starvation? AMPK is the usual suspect

    How does mTOR sense glucose starvation? AMPK is the usual suspect by Gabriel Leprivier, Barak Rotblat

    Published 2020
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  2. 2
    NRF2 and p53: Januses in cancer?

    NRF2 and p53: Januses in cancer? by Barak Rotblat, Gerry Melino, Richard A. Knight

    Published 2012
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  3. 3
    Screening for E3-Ubiquitin ligase inhibitors: challenges and opportunities

    Screening for E3-Ubiquitin ligase inhibitors: challenges and opportunities by Vivien Landré, Barak Rotblat, Sonia Melino, Francesca Bernassola, Gerry Melino

    Published 2014
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  4. 4
    Galectin-1 Is a Novel Structural Component and a Major Regulator of H-Ras Nanoclusters

    Galectin-1 Is a Novel Structural Component and a Major Regulator of H-Ras Nanoclusters by Liron Belanis, Sarah J. Plowman, Barak Rotblat, John F. Hancock, Yoel Kloog

    Published 2008
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  5. 5
    Anti-oxidative stress response genes: bioinformatic analysis of their expression and relevance in multiple cancers

    Anti-oxidative stress response genes: bioinformatic analysis of their expression and relevance in multiple cancers by Barak Rotblat, Thomas G. P. Grünewald, Gabriel Leprivier, Gerry Melino, Richard A. Knight

    Published 2013
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  6. 6
    Galectin-1(L11A) Predicted from a Computed Galectin-1 Farnesyl-Binding Pocket Selectively Inhibits Ras-GTP

    Galectin-1(L11A) Predicted from a Computed Galectin-1 Farnesyl-Binding Pocket Selectively Inhibits Ras-GTP by Barak Rotblat, Hagit Niv, Sabine André, Herbert Kaltner, Hans‐Joachim Gabius, Yoel Kloog

    Published 2004
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  7. 7
    K-Ras Nanoclustering Is Subverted by Overexpression of the Scaffold Protein Galectin-3

    K-Ras Nanoclustering Is Subverted by Overexpression of the Scaffold Protein Galectin-3 by Ruby Shalom‐Feuerstein, Sarah J. Plowman, Barak Rotblat, Nicholas Ariotti, Tianhai Tian, John F. Hancock, Yoel Kloog

    Published 2008
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  8. 8
    Three Separable Domains Regulate GTP-Dependent Association of H-ras with the Plasma Membrane

    Three Separable Domains Regulate GTP-Dependent Association of H-ras with the Plasma Membrane by Barak Rotblat, Ian A. Prior, Cornelia Muncke, Robert G. Parton, Yoel Kloog, Yoav I. Henis, John F. Hancock

    Published 2004
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  9. 9
    IGF1R upregulation confers resistance to isoform-specific inhibitors of PI3K in PIK3CA-driven ovarian cancer

    IGF1R upregulation confers resistance to isoform-specific inhibitors of PI3K in PIK3CA-driven ovarian cancer by Jonathan Zorea, Manu Prasad, Limor Cohen, Nan Li, Roman Schefzik, Susmita Ghosh, Barak Rotblat, Benedikt Brors, Moshe Elkabets

    Published 2018
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  10. 10
    The lncRNA TP73-AS1 is linked to aggressiveness in glioblastoma and promotes temozolomide resistance in glioblastoma cancer stem cells

    The lncRNA TP73-AS1 is linked to aggressiveness in glioblastoma and promotes temozolomide resistance in glioblastoma cancer stem cells by Gal Mazor, Liron Levin, Daniel Picard, Ulvi Ahmadov, Helena Carén, Arndt Borkhardt, Guido Reifenberger, Gabriel Leprivier, Marc Remke, Barak Rotblat

    Published 2019
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  11. 11
    Eukaryotic initiation factor 4E-binding protein 1 (4E-BP1): a master regulator of mRNA translation involved in tumorigenesis

    Eukaryotic initiation factor 4E-binding protein 1 (4E-BP1): a master regulator of mRNA translation involved in tumorigenesis by Julian Musa, Martin F. Orth, Marlene Dallmayer, Michaela C. Baldauf, Catia Lo Pardo, Barak Rotblat, Thomas Kirchner, Gabriel Leprivier, Thomas G. P. Grünewald

    Published 2016
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  12. 12
    High throughput screening for inhibitors of the HECT ubiquitin E3 ligase ITCH identifies antidepressant drugs as regulators of autophagy

    High throughput screening for inhibitors of the HECT ubiquitin E3 ligase ITCH identifies antidepressant drugs as regulators of autophagy by Mario Rossi, Barak Rotblat, Keith H. Ansell, Ivano Amelio, Michele Caraglia, Gabriella Misso, Francesca Bernassola, Claudio N. Cavasotto, Richard A. Knight, Aaron Ciechanover, Gerry Melino

    Published 2014
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  13. 13
    Repression of AXL expression by AP-1/JNK blockage overcomes resistance to PI3Ka therapy

    Repression of AXL expression by AP-1/JNK blockage overcomes resistance to PI3Ka therapy by Mai Badarni, Manu Prasad, Noa Balaban, Jonathan Zorea, Ksenia M. Yegodayev, Ben‐Zion Joshua, Anat Bahat Dinur, Reidar Grénman, Barak Rotblat, Limor Cohen, Moshe Elkabets

    Published 2019
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  14. 14
    Individual Palmitoyl Residues Serve Distinct Roles in H-Ras Trafficking, Microlocalization, and Signaling

    Individual Palmitoyl Residues Serve Distinct Roles in H-Ras Trafficking, Microlocalization, and Signaling by Sandrine Roy, Sarah J. Plowman, Barak Rotblat, Ian A. Prior, Cornelia Muncke, Sarah A. Grainger, Robert G. Parton, Yoav I. Henis, Yoel Kloog, John F. Hancock

    Published 2005
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  15. 15
    Hace1 controls ROS generation of vertebrate Rac1-dependent NADPH oxidase complexes

    Hace1 controls ROS generation of vertebrate Rac1-dependent NADPH oxidase complexes by Mads Daugaard, Roberto Nitsch, Babak Razaghi, Lindsay McDonald, Ameer Jarrar, Stéphanie Torrino, Sonia Castillo‐Lluva, Barak Rotblat, Liheng Li, Angeliki Malliri, Emmanuel Lemichez, Amel Mettouchi, Jason N. Berman, Josef Penninger, Poul H. Sorensen

    Published 2013
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  16. 16
    HACE1 reduces oxidative stress and mutant Huntingtin toxicity by promoting the NRF2 response

    HACE1 reduces oxidative stress and mutant Huntingtin toxicity by promoting the NRF2 response by Barak Rotblat, Amber L. Southwell, Dagmar E. Ehrnhoefer, Niels H. Skotte, Martina Metzler, Sonia Franciosi, Gabriel Leprivier, Syam Prakash Somasekharan, Adi Barokas, Yu Deng, Tiffany Tang, Joan Mathers, Naniye Mallı Cetinbas, Mads Daugaard, Brian Kwok, Liheng Li, Christopher J. Carnie, Dieter Fink, Roberto Nitsch, Jason D. Galpin, Christopher A. Ahern, Gerry Melino, Josef Penninger, Michael R. Hayden, Poul H. Sorensen

    Published 2014
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  17. 17
    MEK1/2 inhibition transiently alters the tumor immune microenvironment to enhance immunotherapy efficacy against head and neck cancer

    MEK1/2 inhibition transiently alters the tumor immune microenvironment to enhance immunotherapy efficacy against head and neck cancer by Manu Prasad, Jonathan Zorea, Sankar Jagadeeshan, Avital Beeri. Shnerb, Sooraj Mathukkada, Jebrane Bouaoud, Lucas Michon, Ofra Novoplansky, Mai Badarni, Limor Cohen, Ksenia M. Yegodayev, Sapir Tzadok, Barak Rotblat, Libor Brezina, Andreas Möck, Andy Karabajakian, Jérôme Fayette, Idan Cohen, Tomer Cooks, Irit Allon, Orr Dimitstein, Ben‐Zion Joshua, Dexin Kong, Elena Voronov, Maurizio Scaltriti, Yaron Carmi, Cristina Conde‐López, Jochen Heß, Ina Kurth, Luc G.T. Morris, Pierre Saintigny, Moshe Elkabets

    Published 2022
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  18. 18
    mTORC1 regulates cell survival under glucose starvation through 4EBP1/2-mediated translational reprogramming of fatty acid metabolism

    mTORC1 regulates cell survival under glucose starvation through 4EBP1/2-mediated translational reprogramming of fatty acid metabolism by Tal Levy, Kai Voeltzke, Laura Hruby, Khawla Alasad, Zuelal Bas, Marteinn T. Snaebjornsson, Ran Marciano, Katerina Scharov, Mélanie Planque, Kim Vriens, Stefan Christen, Cornelius M. Funk, Christina Hassiepen, Alisa Kahler, Beate Heider, Daniel Picard, Jonathan Lim, Anja Stefanski, Katja Bendrin, Andres Vargas‐Toscano, Ulf D. Kahlert, Kai Stühler, Marc Remke, Moshe Elkabets, Thomas G. P. Grünewald, Andreas S. Reichert, Sarah‐Maria Fendt, Almut Schulze, Guido Reifenberger, Barak Rotblat, Gabriel Leprivier

    Published 2024
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  19. 19
    Cooperation of cancer drivers with regulatory germline variants shapes clinical outcomes

    Cooperation of cancer drivers with regulatory germline variants shapes clinical outcomes by Julian Musa, Florencia Cidre‐Aranaz, Marie-Ming Aynaud, Martin F. Orth, Maximilian M. L. Knott, Olivier Mirabeau, Gal Mazor, Mor Varon, Tilman L. B. Hölting, Sandrine Grossetête, Moritz Gartlgruber, Didier Surdez, Julia S. Gerke, Shunya Ohmura, Aruna Marchetto, Marlene Dallmayer, Michaela C. Baldauf, Stefanie Stein, Giuseppina Sannino, Jing Li, Laura Romero‐Pérez, Frank Westermann, Wolfgang Hartmann, Uta Dirksen, Melissa Gymrek, Nathaniel D. Anderson, Adam Shlien, Barak Rotblat, Thomas Kirchner, Olivier Delattre, Thomas G. P. Grünewald

    Published 2019
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  20. 20
    The eEF2 Kinase Confers Resistance to Nutrient Deprivation by Blocking Translation Elongation

    The eEF2 Kinase Confers Resistance to Nutrient Deprivation by Blocking Translation Elongation by Gabriel Leprivier, Marc Remke, Barak Rotblat, Adrian M. Dubuc, Abigail-Rachele F. Mateo, Marcel Kool, Sameer Agnihotri, Amal M. El-Naggar, Bin Yu, Syam Prakash Somasekharan, Brandon Faubert, Gaëlle Bridon, Cristina E. Tognon, Joan Mathers, Ryan M. Thomas, Amy Li, Adi Barokas, Brian Kwok, Mary Bowden, Stephanie Smith, Xiaochong Wu, Andrey Korshunov, Thomas Hielscher, Paul A. Northcott, Jason D. Galpin, Christopher A. Ahern, Ye Wang, Martin G. McCabe, V. Peter Collins, Russell G. Jones, Michaël Pollak, Olivier Delattre, Martin Gleave, Eric Jan, Stefan M. Pfister, Christopher G. Proud, W. Brent Derry, Michael D. Taylor, Poul H. Sorensen

    Published 2013
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