Canlyniadau Chwilio - Babusis, Darius

Viability of primary osteoblasts after treatment with tenofovir alafenamide: Lack of cytotoxicity at clinically relevant drug concentrations gan Callebaut, Christian, Liu, Yang, Babusis, Darius, Ray, Adrian, Miller, Michael, Kitrinos, Kathryn

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Implications of Efficient Hepatic Delivery by Tenofovir Alafenamide (GS-7340) for Hepatitis B Virus Therapy gan Murakami, Eisuke, Wang, Ting, Park, Yeojin, Hao, Jia, Lepist, Eve-Irene, Babusis, Darius, Ray, Adrian S.

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Intracellular Nucleotide Levels during Coadministration of Tenofovir Disoproxil Fumarate and Didanosine in HIV-1-Infected Patients gan Hawkins, Trevor, Veikley, Wenoah, Durand-Gasselin, Lucie, Babusis, Darius, Reddy, Y. Sunila, Flaherty, John F., Ray, Adrian S.

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Two-dose emtricitabine/tenofovir alafenamide plus bictegravir prophylaxis protects macaques against SHIV infection gan Bekerman, Elena, Cox, Stephanie, Babusis, Darius, Campigotto, Federico, Das, Moupali, Barouch, Dan H, Cihlar, Tomas, Callebaut, Christian

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GS-9219/VDC-1101 - a prodrug of the acyclic nucleotide PMEG has antitumor activity inspontaneous canine multiple myeloma gan Thamm, Douglas H, Vail, David M, Kurzman, Ilene D, Babusis, Darius, Ray, Adrian S, Sousa-Powers, Noel, Tumas, Daniel B

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Effects of Human Immunodeficiency Virus Protease Inhibitors on the Intestinal Absorption of Tenofovir Disoproxil Fumarate In Vitro gan Tong, Leah, Phan, Truc K., Robinson, Kelly L., Babusis, Darius, Strab, Robert, Bhoopathy, Siddhartha, Hidalgo, Ismael J., Rhodes, Gerald R., Ray, Adrian S.

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Sofosbuvir and Ribavirin Liver Pharmacokinetics in Patients Infected with Hepatitis C Virus gan Babusis, Darius, Curry, Michael P., Kirby, Brian, Park, Yeojin, Murakami, Eisuke, Wang, Ting, Mathias, Anita, Afdhal, Nezam, McHutchison, John G., Ray, Adrian S.

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Compared to Subcutaneous Tenofovir, Oral Tenofovir Disoproxyl Fumarate Administration Preferentially Concentrates the Drug into Gut-Associated Lymphoid Cells in Simian Immunodefici... gan Van Rompay, Koen K. A., Babusis, Darius, Abbott, Zachary, Geng, Yongzhi, Jayashankar, Kartika, Johnson, Jeffrey A., Lipscomb, Jonathan, Heneine, Walid, Abel, Kristina, Ray, Adrian S.

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Pharmacokinetic, Pharmacodynamic, and Drug-Interaction Profile of Remdesivir, a SARS-CoV-2 Replication Inhibitor gan Humeniuk, Rita, Mathias, Anita, Kirby, Brian J., Lutz, Justin D., Cao, Huyen, Osinusi, Anu, Babusis, Darius, Porter, Danielle, Wei, Xuelian, Ling, John, Reddy, Y. Sunila, German, Polina

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Pomalidomide Shows Significant Therapeutic Activity against CNS Lymphoma with a Major Impact on the Tumor Microenvironment in Murine Models gan Li, Zhimin, Qiu, Yushi, Personett, David, Huang, Peng, Edenfield, Brandy, Katz, Jason, Babusis, Darius, Tang, Yang, Shirely, Michael A., Moghaddam, Mehran F., Copland, John A., Tun, Han W.

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Metabolism and Pharmacokinetics of the Anti-Hepatitis C Virus Nucleotide Prodrug GS-6620 gan Murakami, Eisuke, Wang, Ting, Babusis, Darius, Lepist, Eve-Irene, Sauer, Dorothea, Park, Yeojin, Vela, Jennifer E., Shih, Robert, Birkus, Gabriel, Stefanidis, Dimitrios, Kim, Choung U., Cho, Aesop, Ray, Adrian S.

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Nucleotide Prodrug Containing a Nonproteinogenic Amino Acid To Improve Oral Delivery of a Hepatitis C Virus Treatment gan Feng, Joy Y., Wang, Ting, Park, Yeojin, Babusis, Darius, Birkus, Gabriel, Xu, Yili, Voitenleitner, Christian, Fenaux, Martijn, Yang, Huiling, Eng, Stacey, Tirunagari, Neeraj, Kirschberg, Thorsten, Cho, Aesop, Ray, Adrian S.

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Off-Target In Vitro Profiling Demonstrates that Remdesivir Is a Highly Selective Antiviral Agent gan Xu, Yili, Barauskas, Ona, Kim, Cynthia, Babusis, Darius, Murakami, Eisuke, Kornyeyev, Dmytro, Lee, Gary, Stepan, George, Perron, Michel, Bannister, Roy, Schultz, Brian E., Sakowicz, Roman, Porter, Danielle, Cihlar, Tomas, Feng, Joy Y.

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The Nucleoside/Nucleotide Analogs Tenofovir and Emtricitabine Are Inactive against SARS-CoV-2 gan Feng, Joy Y., Du Pont, Venice, Babusis, Darius, Gordon, Calvin J., Tchesnokov, Egor P., Perry, Jason K., Duong, Vincent, Vijjapurapu, Arya, Zhao, Xiaofeng, Chan, Julie, Cohen, Cal, Juneja, Kavita, Cihlar, Tomas, Götte, Matthias, Bilello, John P.

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Intravenous delivery of GS-441524 is efficacious in the African green monkey model of SARS-CoV-2 infection gan Pitts, Jared, Babusis, Darius, Vermillion, Meghan S., Subramanian, Raju, Barrett, Kim, Lye, Diane, Ma, Bin, Zhao, Xiaofeng, Riola, Nicholas, Xie, Xuping, Kajon, Adriana, Lu, Xianghan, Bannister, Roy, Shi, Pei-Yong, Toteva, Maria, Porter, Danielle P., Smith, Bill J., Cihlar, Tomas, Mackman, Richard, Bilello, John P.

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Metabolic Activation of the Anti-Hepatitis C Virus Nucleotide Prodrug PSI-352938 gan Niu, Congrong, Tolstykh, Tatiana, Bao, Haiying, Park, Yeojin, Babusis, Darius, Lam, Angela M., Bansal, Shalini, Du, Jinfa, Chang, Wonsuk, Reddy, P. Ganapati, Zhang, Hai-Ren, Woolley, Joseph, Wang, Li-Quan, Chao, Piyun B., Ray, Adrian S., Otto, Michael J., Sofia, Michael J., Furman, Phillip A., Murakami, Eisuke

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Sensitivity of Mitochondrial Transcription and Resistance of RNA Polymerase II Dependent Nuclear Transcription to Antiviral Ribonucleosides gan Arnold, Jamie J., Sharma, Suresh D., Feng, Joy Y., Ray, Adrian S., Smidansky, Eric D., Kireeva, Maria L., Cho, Aesop, Perry, Jason, Vela, Jennifer E., Park, Yeojin, Xu, Yili, Tian, Yang, Babusis, Darius, Barauskus, Ona, Peterson, Blake R., Gnatt, Averell, Kashlev, Mikhail, Zhong, Weidong, Cameron, Craig E.

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Comparative therapeutic efficacy of remdesivir and combination lopinavir, ritonavir, and interferon beta against MERS-CoV gan Sheahan, Timothy P., Sims, Amy C., Leist, Sarah R., Schäfer, Alexandra, Won, John, Brown, Ariane J., Montgomery, Stephanie A., Hogg, Alison, Babusis, Darius, Clarke, Michael O., Spahn, Jamie E., Bauer, Laura, Sellers, Scott, Porter, Danielle, Feng, Joy Y., Cihlar, Tomas, Jordan, Robert, Denison, Mark R., Baric, Ralph S.

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Subcutaneous remdesivir administration prevents interstitial pneumonia in rhesus macaques inoculated with SARS-CoV-2 gan Williamson, Brandi N., Pérez-Pérez, Lizzette, Schwarz, Benjamin, Feldmann, Friederike, Holbrook, Myndi G., Singh, Manmeet, Lye, Diane S., Babusis, Darius, Subramanian, Raju, Haddock, Elaine, Okumura, Atsushi, Hanley, Patrick W., Lovaglio, Jamie, Bosio, Catharine M., Porter, Danielle P., Cihlar, Tomas, Mackman, Richard L., Saturday, Greg, de Wit, Emmie

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Oral prodrug of remdesivir parent GS-441524 is efficacious against SARS-CoV-2 in ferrets gan Cox, Robert M., Wolf, Josef D., Lieber, Carolin M., Sourimant, Julien, Lin, Michelle J., Babusis, Darius, DuPont, Venice, Chan, Julie, Barrett, Kim T., Lye, Diane, Kalla, Rao, Chun, Kwon, Mackman, Richard L., Ye, Chengjin, Cihlar, Tomas, Martinez-Sobrido, Luis, Greninger, Alexander L., Bilello, John P., Plemper, Richard K.

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