نتائج البحث - Babusis, Darius

Viability of primary osteoblasts after treatment with tenofovir alafenamide: Lack of cytotoxicity at clinically relevant drug concentrations حسب Callebaut, Christian, Liu, Yang, Babusis, Darius, Ray, Adrian, Miller, Michael, Kitrinos, Kathryn

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Implications of Efficient Hepatic Delivery by Tenofovir Alafenamide (GS-7340) for Hepatitis B Virus Therapy حسب Murakami, Eisuke, Wang, Ting, Park, Yeojin, Hao, Jia, Lepist, Eve-Irene, Babusis, Darius, Ray, Adrian S.

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Intracellular Nucleotide Levels during Coadministration of Tenofovir Disoproxil Fumarate and Didanosine in HIV-1-Infected Patients حسب Hawkins, Trevor, Veikley, Wenoah, Durand-Gasselin, Lucie, Babusis, Darius, Reddy, Y. Sunila, Flaherty, John F., Ray, Adrian S.

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Two-dose emtricitabine/tenofovir alafenamide plus bictegravir prophylaxis protects macaques against SHIV infection حسب Bekerman, Elena, Cox, Stephanie, Babusis, Darius, Campigotto, Federico, Das, Moupali, Barouch, Dan H, Cihlar, Tomas, Callebaut, Christian

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GS-9219/VDC-1101 - a prodrug of the acyclic nucleotide PMEG has antitumor activity inspontaneous canine multiple myeloma حسب Thamm, Douglas H, Vail, David M, Kurzman, Ilene D, Babusis, Darius, Ray, Adrian S, Sousa-Powers, Noel, Tumas, Daniel B

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Effects of Human Immunodeficiency Virus Protease Inhibitors on the Intestinal Absorption of Tenofovir Disoproxil Fumarate In Vitro حسب Tong, Leah, Phan, Truc K., Robinson, Kelly L., Babusis, Darius, Strab, Robert, Bhoopathy, Siddhartha, Hidalgo, Ismael J., Rhodes, Gerald R., Ray, Adrian S.

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Sofosbuvir and Ribavirin Liver Pharmacokinetics in Patients Infected with Hepatitis C Virus حسب Babusis, Darius, Curry, Michael P., Kirby, Brian, Park, Yeojin, Murakami, Eisuke, Wang, Ting, Mathias, Anita, Afdhal, Nezam, McHutchison, John G., Ray, Adrian S.

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Compared to Subcutaneous Tenofovir, Oral Tenofovir Disoproxyl Fumarate Administration Preferentially Concentrates the Drug into Gut-Associated Lymphoid Cells in Simian Immunodefici... حسب Van Rompay, Koen K. A., Babusis, Darius, Abbott, Zachary, Geng, Yongzhi, Jayashankar, Kartika, Johnson, Jeffrey A., Lipscomb, Jonathan, Heneine, Walid, Abel, Kristina, Ray, Adrian S.

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Pharmacokinetic, Pharmacodynamic, and Drug-Interaction Profile of Remdesivir, a SARS-CoV-2 Replication Inhibitor حسب Humeniuk, Rita, Mathias, Anita, Kirby, Brian J., Lutz, Justin D., Cao, Huyen, Osinusi, Anu, Babusis, Darius, Porter, Danielle, Wei, Xuelian, Ling, John, Reddy, Y. Sunila, German, Polina

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Pomalidomide Shows Significant Therapeutic Activity against CNS Lymphoma with a Major Impact on the Tumor Microenvironment in Murine Models حسب Li, Zhimin, Qiu, Yushi, Personett, David, Huang, Peng, Edenfield, Brandy, Katz, Jason, Babusis, Darius, Tang, Yang, Shirely, Michael A., Moghaddam, Mehran F., Copland, John A., Tun, Han W.

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Metabolism and Pharmacokinetics of the Anti-Hepatitis C Virus Nucleotide Prodrug GS-6620 حسب Murakami, Eisuke, Wang, Ting, Babusis, Darius, Lepist, Eve-Irene, Sauer, Dorothea, Park, Yeojin, Vela, Jennifer E., Shih, Robert, Birkus, Gabriel, Stefanidis, Dimitrios, Kim, Choung U., Cho, Aesop, Ray, Adrian S.

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Nucleotide Prodrug Containing a Nonproteinogenic Amino Acid To Improve Oral Delivery of a Hepatitis C Virus Treatment حسب Feng, Joy Y., Wang, Ting, Park, Yeojin, Babusis, Darius, Birkus, Gabriel, Xu, Yili, Voitenleitner, Christian, Fenaux, Martijn, Yang, Huiling, Eng, Stacey, Tirunagari, Neeraj, Kirschberg, Thorsten, Cho, Aesop, Ray, Adrian S.

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Off-Target In Vitro Profiling Demonstrates that Remdesivir Is a Highly Selective Antiviral Agent حسب Xu, Yili, Barauskas, Ona, Kim, Cynthia, Babusis, Darius, Murakami, Eisuke, Kornyeyev, Dmytro, Lee, Gary, Stepan, George, Perron, Michel, Bannister, Roy, Schultz, Brian E., Sakowicz, Roman, Porter, Danielle, Cihlar, Tomas, Feng, Joy Y.

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The Nucleoside/Nucleotide Analogs Tenofovir and Emtricitabine Are Inactive against SARS-CoV-2 حسب Feng, Joy Y., Du Pont, Venice, Babusis, Darius, Gordon, Calvin J., Tchesnokov, Egor P., Perry, Jason K., Duong, Vincent, Vijjapurapu, Arya, Zhao, Xiaofeng, Chan, Julie, Cohen, Cal, Juneja, Kavita, Cihlar, Tomas, Götte, Matthias, Bilello, John P.

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Intravenous delivery of GS-441524 is efficacious in the African green monkey model of SARS-CoV-2 infection حسب Pitts, Jared, Babusis, Darius, Vermillion, Meghan S., Subramanian, Raju, Barrett, Kim, Lye, Diane, Ma, Bin, Zhao, Xiaofeng, Riola, Nicholas, Xie, Xuping, Kajon, Adriana, Lu, Xianghan, Bannister, Roy, Shi, Pei-Yong, Toteva, Maria, Porter, Danielle P., Smith, Bill J., Cihlar, Tomas, Mackman, Richard, Bilello, John P.

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Metabolic Activation of the Anti-Hepatitis C Virus Nucleotide Prodrug PSI-352938 حسب Niu, Congrong, Tolstykh, Tatiana, Bao, Haiying, Park, Yeojin, Babusis, Darius, Lam, Angela M., Bansal, Shalini, Du, Jinfa, Chang, Wonsuk, Reddy, P. Ganapati, Zhang, Hai-Ren, Woolley, Joseph, Wang, Li-Quan, Chao, Piyun B., Ray, Adrian S., Otto, Michael J., Sofia, Michael J., Furman, Phillip A., Murakami, Eisuke

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Sensitivity of Mitochondrial Transcription and Resistance of RNA Polymerase II Dependent Nuclear Transcription to Antiviral Ribonucleosides حسب Arnold, Jamie J., Sharma, Suresh D., Feng, Joy Y., Ray, Adrian S., Smidansky, Eric D., Kireeva, Maria L., Cho, Aesop, Perry, Jason, Vela, Jennifer E., Park, Yeojin, Xu, Yili, Tian, Yang, Babusis, Darius, Barauskus, Ona, Peterson, Blake R., Gnatt, Averell, Kashlev, Mikhail, Zhong, Weidong, Cameron, Craig E.

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Comparative therapeutic efficacy of remdesivir and combination lopinavir, ritonavir, and interferon beta against MERS-CoV حسب Sheahan, Timothy P., Sims, Amy C., Leist, Sarah R., Schäfer, Alexandra, Won, John, Brown, Ariane J., Montgomery, Stephanie A., Hogg, Alison, Babusis, Darius, Clarke, Michael O., Spahn, Jamie E., Bauer, Laura, Sellers, Scott, Porter, Danielle, Feng, Joy Y., Cihlar, Tomas, Jordan, Robert, Denison, Mark R., Baric, Ralph S.

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Subcutaneous remdesivir administration prevents interstitial pneumonia in rhesus macaques inoculated with SARS-CoV-2 حسب Williamson, Brandi N., Pérez-Pérez, Lizzette, Schwarz, Benjamin, Feldmann, Friederike, Holbrook, Myndi G., Singh, Manmeet, Lye, Diane S., Babusis, Darius, Subramanian, Raju, Haddock, Elaine, Okumura, Atsushi, Hanley, Patrick W., Lovaglio, Jamie, Bosio, Catharine M., Porter, Danielle P., Cihlar, Tomas, Mackman, Richard L., Saturday, Greg, de Wit, Emmie

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Oral prodrug of remdesivir parent GS-441524 is efficacious against SARS-CoV-2 in ferrets حسب Cox, Robert M., Wolf, Josef D., Lieber, Carolin M., Sourimant, Julien, Lin, Michelle J., Babusis, Darius, DuPont, Venice, Chan, Julie, Barrett, Kim T., Lye, Diane, Kalla, Rao, Chun, Kwon, Mackman, Richard L., Ye, Chengjin, Cihlar, Tomas, Martinez-Sobrido, Luis, Greninger, Alexander L., Bilello, John P., Plemper, Richard K.

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