Výsledky vyhledávání - Ayşe Demirkan

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  1. 1
    Metagenomics of Parkinson’s disease implicates the gut microbiome in multiple disease mechanisms

    Metagenomics of Parkinson’s disease implicates the gut microbiome in multiple disease mechanisms Autor Zachary D. Wallen, Ayşe Demirkan, Guy Twa, Gwendolyn Cohen, Marissa Dean, David G. Standaert, Timothy R. Sampson, Haydeh Payami

    Vydáno 2022
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  2. 2
    Adipose Tissue Gene Expression of Adiponectin, Tumor Necrosis Factor-.ALPHA. and Leptin in Metabolic Syndrome Patients with Coronary Artery Disease

    Adipose Tissue Gene Expression of Adiponectin, Tumor Necrosis Factor-.ALPHA. and Leptin in Metabolic Syndrome Patients with Coronary Artery Disease Autor Selçuk Görmez, Ayşe Demirkan, Fatmahan Atalar, Barış Çaynak, Refik Erdim, Volkan Sözer, Demet Günay, Bellhan Akpinar, Uğur Özbek, Ahmet Sevim Buyukdevrim

    Vydáno 2011
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  3. 3
    A Mendelian Randomization Study of Metabolite Profiles, Fasting Glucose, and Type 2 Diabetes

    A Mendelian Randomization Study of Metabolite Profiles, Fasting Glucose, and Type 2 Diabetes Autor Jun Liu, Jan B. van Klinken, Sabina Semiz, Ko Willems van Dijk, Aswin Verhoeven, Thomas Hankemeier, Amy C. Harms, Eric J.G. Sijbrands, Nuala A. Sheehan, Cornelia M. van Duijn, Ayşe Demirkan

    Vydáno 2017
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  4. 4
    Mechanistic Heterogeneity in Type 2 Diabetes and Hypertension Comorbidity Revealed with Partitioned Polygenic Scores

    Mechanistic Heterogeneity in Type 2 Diabetes and Hypertension Comorbidity Revealed with Partitioned Polygenic Scores Autor Vincent Pascat, Liudmila Zudina, Lucas Maurin, Anna Ulrich, Jared G. Maina, Ayşe Demirkan, Zhanna Balkhiyarova, Igor Pupko, Yevheniya Sharhorodska, François Pattou, Bart Staels, Marika Kaakinen, Amna Khamis, Amélie Bonnefond, Patricia B. Munroe, Philippe Froguel, Inga Prokopenko

    Vydáno 2025
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  5. 5
    Metabolomics based markers predict type 2 diabetes in a 14-year follow-up study

    Metabolomics based markers predict type 2 diabetes in a 14-year follow-up study Autor Jun Liu, Sabina Semiz, Sven J. van der Lee, Ashley van der Spek, Aswin Verhoeven, Jan B. van Klinken, Eric J.G. Sijbrands, Amy C. Harms, Thomas Hankemeier, Ko Willems van Dijk, Cornelia M. van Duijn, Ayşe Demirkan

    Vydáno 2017
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  6. 6
    Insight in Genome-Wide Association of Metabolite Quantitative Traits by Exome Sequence Analyses

    Insight in Genome-Wide Association of Metabolite Quantitative Traits by Exome Sequence Analyses Autor Ayşe Demirkan, Peter Henneman, Aswin Verhoeven, Harish Dharuri, Najaf Amin, Jan B. van Klinken, Lennart C. Karssen, Boukje de Vries, Axel Meißner, Sibel Göraler, Arn M. J. M. van den Maagdenberg, André M. Deelder, Peter A.C. ‘t Hoen, Cornelia M. van Duijn, Ko Willems van Dijk

    Vydáno 2015
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  7. 7
    Lipidomic profiling identifies signatures of metabolic risk

    Lipidomic profiling identifies signatures of metabolic risk Autor Xiaoyan Yin, Christine Willinger, Joshua A. Keefe, Jun Liu, Antonio Fernández-Ortı́z, Borja Ibáñez, José L. Peñalvo, Aram Adourian, George Chen, Dolores Corella, Reinald Pamplona, Manuel Portero‐Otín, Mariona Jové, Paul Courchesne, Cornelia M. van Duijn, Valentı́n Fuster, José M. Ordovás, Ayşe Demirkan, Martin G. Larson, Daniel Levy

    Vydáno 2019
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  8. 8
    Blood‐based metabolic signatures in Alzheimer's disease

    Blood‐based metabolic signatures in Alzheimer's disease Autor Francisca A. de Leeuw, Carel F.W. Peeters, Maartje I. Kester, Amy C. Harms, Eduard A. Struys, Thomas Hankemeier, Herman van Vlijmen, Sven J. van der Lee, Cornelia M. van Duijn, Philip Scheltens, Ayşe Demirkan, Mark A. van de Wiel, Wiesje M. van der Flier, Charlotte E. Teunissen

    Vydáno 2017
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  9. 9
    Genetic risk profiles for depression and anxiety in adult and elderly cohorts

    Genetic risk profiles for depression and anxiety in adult and elderly cohorts Autor Ayşe Demirkan, Brenda W.J.H. Penninx, Karin Hek, Naomi R. Wray, Najaf Amin, Yurii S. Aulchenko, Richard van Dyck, Eco J. C. de Geus, Roelande Hofman, André G. Uitterlinden, J-J Hottenga, W.A. Nolen, B. A. Oostra, Patrick F. Sullivan, Gonneke Willemsen, Frans G. Zitman, Henning Tiemeier, A. Cecile J.W. Janssens, Dorret I. Boomsma, Cornelia M. van Duijn, Christel M. Middeldorp

    Vydáno 2010
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  10. 10
    Association of branched‐chain amino acids and other circulating metabolites with risk of incident dementia and Alzheimer's disease: A prospective study in eight cohorts

    Association of branched‐chain amino acids and other circulating metabolites with risk of incident dementia and Alzheimer's disease: A prospective study in eight cohorts Autor Juho Tynkkynen, Vincent Chouraki, Sven J. van der Lee, Jussi Hernesniemi, Qiong Yang, Shuo Li, Alexa Beiser, Martin G. Larson, Katri Sääksjärvi, Martin J. Shipley, Archana Singh‐Manoux, Robert E. Gerszten, Thomas J. Wang, Aki S. Havulinna, Peter Würtz, Krista Fischer, Ayşe Demirkan, M. Arfan Ikram, Najaf Amin, Terho Lehtimäki, Mika Kähönen, Markus Perola, Andres Metspalu, Antti J. Kangas, Pasi Soininen, Mika Ala‐Korpela, Ramachandran S. Vasan, Mika Kivimäki, Cornelia M. van Duijn, Sudha Seshadri, Veikko Salomaa

    Vydáno 2018
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  11. 11
    Large-scale whole-exome sequencing association studies identify rare functional variants influencing serum urate levels

    Large-scale whole-exome sequencing association studies identify rare functional variants influencing serum urate levels Autor Adrienne Tin, Yong Li, Jennifer A. Brody, Teresa Nutile, Audrey Y. Chu, Jennifer E. Huffman, Qiong Yang, Ming‐Huei Chen, Cassianne Robinson‐Cohen, Aurélien Macé, Jun Liu, Ayşe Demirkan, Rossella Sorice, Sanaz Sedaghat, Melody Swen, Bing Yu, Sahar Ghasemi, Alexander Teumer, Péter Vollenweider, Marina Ciullo, Meng Li, André G. Uitterlinden, Robert Kraaij, Najaf Amin, Jeroen van Rooij, Zoltán Kutalik, Abbas Dehghan, Barbara McKnight, Cornelia M. van Duijn, Alanna C. Morrison, Bruce M. Psaty, Eric Boerwinkle, Caroline S. Fox, Owen M. Woodward, Anna Köttgen

    Vydáno 2018
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  12. 12
    The Neuronal Transporter Gene SLC6A15 Confers Risk to Major Depression

    The Neuronal Transporter Gene SLC6A15 Confers Risk to Major Depression Autor Martin Kohli, Susanne Lucae, Philipp G. Saemann, Mathias V. Schmidt, Ayşe Demirkan, Karin Hek, Darina Czamara, Michael P. Alexander, Daria Salyakina, Stephan Ripke, David Hoehn, Michael Specht, Andreas Menke, Johannes M. Hennings, Angela Heck, Christiane Wolf, Marcus Ising, Stefan Schreiber, Michael Czisch, Marianne B. Müller, Manfred Uhr, Thomas Bettecken, Albert J. Becker, Johannes Schramm, Marcella Rietschel, Wolfgang Maier, Bekh Bradley, Kerry J. Ressler, Markus M. Nöthen, Sven Cichon, Ian Craig, Gerome Breen, Cathryn M. Lewis, Albert Hofman, Henning Tiemeier, Cornelia M. van Duijn, Herta Flor, Bertram Müller‐Myhsok, Elisabeth B. Binder

    Vydáno 2011
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  13. 13
    A metabolic profile of all-cause mortality risk identified in an observational study of 44,168 individuals

    A metabolic profile of all-cause mortality risk identified in an observational study of 44,168 individuals Autor Joris Deelen, Johannes Kettunen, Krista Fischer, Ashley van der Spek, Stella Trompet, Gabi Kastenmüller, Andy Boyd, Jonas Zierer, Erik B. van den Akker, Mika Ala‐Korpela, Najaf Amin, Ayşe Demirkan, Mohsen Ghanbari, Alan B. Zonderman, M. Arfan Ikram, Jan B. van Klinken, Simon P. Mooijaart, Annette Peters, Veikko Salomaa, Naveed Sattar, Tim D. Spector, Henning Tiemeier, Aswin Verhoeven, Mélanie Waldenberger, Peter Würtz, George Davey Smith, Andres Metspalu, Markus Perola, Cristina Menni, Johanna M. Geleijnse, Fotios Drenos, Marian Beekman, J. Wouter Jukema, Cornelia M. van Duijn, P. Eline Slagboom

    Vydáno 2019
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  14. 14
    Large-scale plasma metabolome analysis reveals alterations in HDL metabolism in migraine

    Large-scale plasma metabolome analysis reveals alterations in HDL metabolism in migraine Autor Gerrit L.J. Onderwater, Lannie Ligthart, Mariska Bot, Ayşe Demirkan, Jingyuan Fu, Carla Kallen, Lisanne S. Vijfhuizen, René Pool, Jun Liu, Floris Vanmolkot, Marian Beekman, Kexin Wen, Najaf Amin, Carisha S. Thesing, Judith A. Pijpers, Dennis A. Kies, Ronald Zielman, Irene de Boer, Marleen M. J. van Greevenbroek, Ilja C.W. Arts, Yuri Milaneschi, Miranda T. Schram, Pieter C. Dagnelie, Lude Franke, M. Arfan Ikram, Michel D. Ferrari, Jelle J. Goeman, P. Eline Slagboom, Cisca Wijmenga, Coen D.A. Stehouwer, Dorret I. Boomsma, Cornelia M. van Duijn, Brenda W.J.H. Penninx, Peter A.C. ‘t Hoen, Gisela M. Terwindt, Arn M. J. M. van den Maagdenberg

    Vydáno 2019
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  15. 15
    Effects of Metformin on Metabolite Profiles and LDL Cholesterol in Patients With Type 2 Diabetes

    Effects of Metformin on Metabolite Profiles and LDL Cholesterol in Patients With Type 2 Diabetes Autor Tao Xu, Stefan Brandmaier, Ana C. Messias, Christian Herder, Harmen H. M. Draisma, Ayşe Demirkan, Zhonghao Yu, Janina S. Ried, Toomas Haller, Margit Heier, Mónica Campillos, Gisela Fobo, Renée Stark, Christina Holzapfel, Jonathan Adam, Shen Chi, Markus Rotter, Tommaso Panni, Anne S. Quante, Ying He, Cornelia Prehn, Werner Roemisch‐Margl, Gabi Kastenmüller, Gonneke Willemsen, René Pool, Katarina Kasa, Ko Willems van Dijk, Thomas Hankemeier, Christa Meisinger, Barbara Thorand, Andreas Ruepp, Martin Hrabě de Angelis, Yixue Li, H.‐Erich Wichmann, Bernd Stratmann, Konstantin Strauch, Andres Metspalu, Christian Gieger, Karsten Suhre, Jerzy Adamski, Thomas Illig, Wolfgang Rathmann, Michael Roden, Annette Peters, Cornelia M. van Duijn, Dorret I. Boomsma, Thomas Meitinger, Rui Wang‐Sattler

    Vydáno 2015
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  16. 16
    Genetic Determinants of Circulating Sphingolipid Concentrations in European Populations

    Genetic Determinants of Circulating Sphingolipid Concentrations in European Populations Autor Andrew A. Hicks, Peter P. Pramstaller, Åsa Johansson, Véronique Vitart, Igor Rudan, Péter Ugocsai, Yurii S. Aulchenko, Christopher S. Franklin, Gerhard Liebisch, Jeanette Erdmann, Inger Jonasson, Irina V. Zorkoltseva, Cristian Pattaro, Caroline Hayward, Aaron Isaacs, Christian Hengstenberg, Susan Campbell, Carsten Gnewuch, A. Cecile J.W. Janssens, Anatoly V. Kirichenko, Inke R. König, Fabio Marroni, Ozren Polašek, Ayşe Demirkan, Ivana Kolčić, Christine Schwienbacher, Wilmar Igl, Zrinka Biloglav, Jacqueline C.M. Witteman, Irene Pichler, Ghazal Zaboli, Tatiana I. Axenovich, Annette Peters, Stefan Schreiber, H.‐Erich Wichmann, Heribert Schunkert, Nick Hastie, Ben A. Oostra, Sarah H. Wild, Thomas Meitinger, Ulf Gyllensten, Cornelia M. van Duijn, James F. Wilson, Alan F. Wright, Gerd Schmitz, Harry Campbell

    Vydáno 2009
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  17. 17
    Metabolomics Profile in Depression: A Pooled Analysis of 230 Metabolic Markers in 5283 Cases With Depression and 10,145 Controls

    Metabolomics Profile in Depression: A Pooled Analysis of 230 Metabolic Markers in 5283 Cases With Depression and 10,145 Controls Autor Mariska Bot, Yuri Milaneschi, Tahani Alshehri, Najaf Amin, Sanzhima Garmaeva, Gerrit L.J. Onderwater, René Pool, Carisha S. Thesing, Lisanne S. Vijfhuizen, Nicole Vogelzangs, Ilja C.W. Arts, Ayşe Demirkan, Cornelia M. van Duijn, Marleen M. J. van Greevenbroek, Carla Kallen, Sebastian Köhler, Lannie Ligthart, Anouk den Braber, Dennis O. Mook‐Kanamori, Renée de Mutsert, Henning Tiemeier, Miranda T. Schram, Coen D.A. Stehouwer, Gisela M. Terwindt, Ko Willems van Dijk, Jingyuan Fu, Alexandra Zhernakova, Marian Beekman, P. Eline Slagboom, Dorret I. Boomsma, Brenda W.J.H. Penninx, Marian Beekman, H. Eka D. Suchiman, Joris Deelen, Najaf Amin, Joline W. J. Beulens, Joana Bom, Nils Bömer, Ayşe Demirkan, J. A. van Hilten, Jennifer Meessen, René Pool, Matthijs Moed, Jingyuan Fu, Gerrit L.J. Onderwater, Femke Rutters, Cynthia So‐Osman, Wiesje M. van der Flier, Amber A. van der Heijden, Ashley van der Spek, Folkert W. Asselbergs, Eric Boersma, Petra J. M. Elders, Johanna M. Geleijnse, M. Arfan Ikram, M. Kloppenburg, Ingrid Meulenbelt, S.P. Mooijaart, Rob G. H. H. Nelissen, M. G. Netea, Brenda W.J.H. Penninx, Coen D.A. Stehouwer, Charlotte E. Teunissen, Gisela M. Terwindt, Leen M. ‘t Hart, Anouk den Braber, Pim van der Harst, Iwan C.C. van der Horst, Carla Kallen, Marleen M. J. van Greevenbroek, W.E. van Spil, Cisca Wijmenga, A. H. Zwinderman, A. Zhernikova, J. Wouter Jukema, Naveed Sattar

    Vydáno 2019
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  18. 18
    Metabolic network failures in Alzheimer's disease: A biochemical road map

    Metabolic network failures in Alzheimer's disease: A biochemical road map Autor Jon B. Toledo, Matthias Arnold, Gabi Kastenmüller, Rui Chang, Rebecca Baillie, Xianlin Han, Madhav Thambisetty, Jessica D. Tenenbaum, Karsten Suhre, Paul M. Thompson, Lisa St. John‐Williams, Siamak MahmoudianDehkordi, Daniel M. Rotroff, John Jack, Alison A. Motsinger‐Reif, Shannon L. Risacher, Colette Blach, Joseph E. Lucas, Tyler Massaro, Gregory Louie, Hongjie Zhu, Guido Dallmann, Kristaps Klavins, Therese Koal, Sungeun Kim, Kwangsik Nho, Li Shen, Ramon Casanova, Sudhir Varma, Cristina Legido‐Quigley, M. Arthur Moseley, Kuixi Zhu, Marc Henrion, Sven J. van der Lee, Amy C. Harms, Ayşe Demirkan, Thomas Hankemeier, Cornelia M. van Duijn, John Q. Trojanowski, Leslie M. Shaw, Andrew J. Saykin, Michael W. Weiner, P. Murali Doraiswamy, Rima Kaddurah‐Daouk

    Vydáno 2017
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  19. 19
    Genome-wide study for circulating metabolites identifies 62 loci and reveals novel systemic effects of LPA

    Genome-wide study for circulating metabolites identifies 62 loci and reveals novel systemic effects of LPA Autor Johannes Kettunen, Ayşe Demirkan, Peter Würtz, Harmen H. M. Draisma, Toomas Haller, Rajesh Rawal, Anika A. M. Vaarhorst, Antti J. Kangas, Leo‐Pekka Lyytikäinen, Matti Pirinen, René Pool, Antti‐Pekka Sarin, Pasi Soininen, Taru Tukiainen, Qin Wang, Mika Tiainen, Tuulia Tynkkynen, Najaf Amin, Tanja Zeller, Marian Beekman, Joris Deelen, Ko Willems van Dijk, Tõnu Esko, Jouke‐Jan Hottenga, Jin‐Moo Lee, Terho Lehtimäki, Evelin Mihailov, Richard J. Rose, Anton J. M. de Craen, Christian Gieger, Mika Kähönen, Markus Perola, Stefan Blankenberg, Markku J. Savolainen, Aswin Verhoeven, Jorma Viikari, Gonneke Willemsen, Dorret I. Boomsma, Cornelia M. van Duijn, Johan G. Eriksson, Antti Jula, Marjo‐Riitta Järvelin, Jaakko Kaprio, Andres Metspalu, Olli T. Raitakari, Veikko Salomaa, P. Eline Slagboom, Mélanie Waldenberger, Samuli Ripatti, Mika Ala‐Korpela

    Vydáno 2016
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  20. 20
    Circulating metabolites and general cognitive ability and dementia: Evidence from 11 cohort studies

    Circulating metabolites and general cognitive ability and dementia: Evidence from 11 cohort studies Autor Sven J. van der Lee, Charlotte E. Teunissen, René Pool, Martin J. Shipley, Alexander Teumer, Vincent Chouraki, Debora Melo van Lent, Juho Tynkkynen, Krista Fischer, Jussi Hernesniemi, Toomas Haller, Archana Singh‐Manoux, Aswin Verhoeven, Gonneke Willemsen, Francisca A. de Leeuw, Holger Wagner, Jenny van Dongen, Johannes Hertel, Kathrin Budde, Ko Willems van Dijk, Leonie Weinhold, M. Arfan Ikram, Maik Pietzner, Markus Perola, Michael Wagner, Nele Friedrich, P. Eline Slagboom, Philip Scheltens, Qiong Yang, Robert E. Gertzen, Sarah Egert, Shuo Li, Thomas Hankemeier, C.E.M. van Beijsterveldt, Ramachandran S. Vasan, Wolfgang Maier, Carel F.W. Peeters, Hans J. Grabe, Alfredo Ramı́rez, Sudha Seshadri, Andres Metspalu, Mika Kivimäki, Veikko Salomaa, Ayşe Demirkan, Dorret I. Boomsma, Wiesje M. van der Flier, Najaf Amin, Cornelia M. van Duijn

    Vydáno 2018
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