نتائج البحث - Aviad Tsherniak
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Complementary information derived from CRISPR Cas9 mediated gene deletion and suppression حسب Joseph Rosenbluh, Han Xu, William F. Harrington, Stanley Gill, Xiaoxing Wang, Francisca Vázquez, David E. Root, Aviad Tsherniak, William C. Hahn
منشور في 2017Artigo -
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Chronos: a CRISPR cell population dynamics model حسب Joshua M. Dempster, Isabella Boyle, Francisca Vázquez, David E. Root, Jesse S. Boehm, William C. Hahn, Aviad Tsherniak, James M. McFarland
منشور في 2021Pré-impressão -
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Chronos: a cell population dynamics model of CRISPR experiments that improves inference of gene fitness effects حسب Joshua M. Dempster, Isabella Boyle, Francisca Vázquez, David E. Root, Jesse S. Boehm, William C. Hahn, Aviad Tsherniak, James M. McFarland
منشور في 2021Artigo -
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Sparse dictionary learning recovers pleiotropy from human cell fitness screens حسب Joshua Pan, Jason J. Kwon, Jessica A. Talamas, Ashir A. Borah, Francisca Vázquez, Jesse S. Boehm, Aviad Tsherniak, Marinka Žitnik, James M. McFarland, William C. Hahn
منشور في 2022Artigo -
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Functional, chemical genomic, and super-enhancer screening identify sensitivity to cyclin D1/CDK4 pathway inhibition in Ewing sarcoma حسب Alyssa L. Kennedy, Mounica Vallurupalli, Liying Chen, Brian D. Crompton, Glenn S. Cowley, Francisca Vázquez, Barbara A. Weir, Aviad Tsherniak, Sudha Parasuraman, Sunkyu Kim, Gabriela Alexe, Kimberly Stegmaier
منشور في 2015Artigo -
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Predicting Relapse in Patients With Medulloblastoma by Integrating Evidence From Clinical and Genomic Features حسب Pablo Tamayo, Yoon-Jae Cho, Aviad Tsherniak, Heidi Greulich, Lauren Ambrogio, Netteke Schouten-van Meeteren, Tianni Zhou, Allen Buxton, Marcel Kool, Matthew Meyerson, Scott L. Pomeroy, Jill P. Mesirov
منشور في 2011Artigo -
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Multiplex CRISPR/Cas9-Based Genome Editing in Human Hematopoietic Stem Cells Models Clonal Hematopoiesis and Myeloid Neoplasia حسب Zuzana Tóthová, John M. Krill-Burger, Katerina D. Popova, Catherine C. Landers, Quinlan Sievers, David Yudovich, Roger Belizaire, Jon C. Aster, Elizabeth A. Morgan, Aviad Tsherniak, Benjamin L. Ebert
منشور في 2017Artigo -
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Genome-Wide Interrogation of Human Cancers Identifies EGLN1 Dependency in Clear Cell Ovarian Cancers حسب Colles Price, Stanley Gill, Zandra V. Ho, Shawn M. Davidson, Erin Merkel, James M. McFarland, Lisa Leung, Andrew Tang, Maria Kost‐Alimova, Aviad Tsherniak, Oliver Jonas, Francisca Vázquez, William C. Hahn
منشور في 2019Artigo -
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Partial gene suppression improves identification of cancer vulnerabilities when CRISPR-Cas9 knockout is pan-lethal حسب John M. Krill-Burger, Joshua M. Dempster, Ashir A. Borah, Brenton R. Paolella, David E. Root, Todd R. Golub, Jesse S. Boehm, William C. Hahn, James M. McFarland, Francisca Vázquez, Aviad Tsherniak
منشور في 2023Artigo -
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SWI/SNF-mutant cancers depend on catalytic and non-catalytic activity of EZH2 حسب Kimberly H. Kim, Woojin Kim, Thomas P. Howard, Francisca Vázquez, Aviad Tsherniak, Jennifer N. Wu, Weishan Wang, Jeffrey R. Haswell, Loren D. Walensky, William C. Hahn, Stuart H. Orkin, Charles W.M. Roberts
منشور في 2015Artigo -
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Interrogation of Mammalian Protein Complex Structure, Function, and Membership Using Genome-Scale Fitness Screens حسب Joshua Pan, Robin M. Meyers, Brittany C. Michel, Nazar Mashtalir, Ann E. Sizemore, Jonathan N. Wells, Seth H. Cassel, Francisca Vázquez, Barbara A. Weir, William C. Hahn, Joseph A. Marsh, Aviad Tsherniak, Cigall Kadoch
منشور في 2018Artigo -
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Integrated cross-study datasets of genetic dependencies in cancer حسب Clare Pacini, Joshua M. Dempster, Isabella Boyle, Emanuel Gonçalves, Hanna Najgebauer, Emre Karakoç, Dieudonne van der Meer, Andrew Barthorpe, Howard Lightfoot, Patricia Jaaks, James M. McFarland, Mathew J. Garnett, Aviad Tsherniak, Francesco Iorio
منشور في 2021Artigo -
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ATARiS: Computational quantification of gene suppression phenotypes from multisample RNAi screens حسب Diane D. Shao, Aviad Tsherniak, Shuba Gopal, Barbara A. Weir, Pablo Tamayo, Nicolas Stransky, Steven E. Schumacher, Travis Zack, Rameen Beroukhim, Levi A. Garraway, Adam A. Margolin, David E. Root, William C. Hahn, Jill P. Mesirov
منشور في 2012Artigo -
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Improved estimation of cancer dependencies from large-scale RNAi screens using model-based normalization and data integration حسب James M. McFarland, Zandra V. Ho, Guillaume Kugener, Joshua M. Dempster, Phillip G. Montgomery, Jordan Bryan, John M. Krill-Burger, Thomas Green, Francisca Vázquez, Jesse S. Boehm, Todd R. Golub, William C. Hahn, David E. Root, Aviad Tsherniak
منشور في 2018Artigo -
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Genome-scale CRISPR-Cas9 screen identifies druggable dependencies in <i>TP53</i> wild-type Ewing sarcoma حسب Björn Stolte, Amanda Balboni Iniguez, Neekesh V. Dharia, Amanda L. Robichaud, Amy Saur Conway, Ann M. Morgan, Gabriela Alexe, Nathan J. Schauer, Xiaoxi Liu, Gregory H. Bird, Aviad Tsherniak, Francisca Vázquez, Sara J. Buhrlage, Loren D. Walensky, Kimberly Stegmaier
منشور في 2018Artigo -
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Identification of ADAR1 adenosine deaminase dependency in a subset of cancer cells حسب Hugh Gannon, Tao Zou, Michael K. Kießling, Galen F. Gao, Diana Cai, Peter S. Choi, Alexandru P. Ivan, Ilana Buchumenski, Ashton C. Berger, Jonathan T. Goldstein, Andrew D. Cherniack, Francisca Vázquez, Aviad Tsherniak, Erez Y. Levanon, William C. Hahn, Matthew Meyerson
منشور في 2018Artigo -
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Mitochondrial metabolism promotes adaptation to proteotoxic stress حسب Peter Tsvetkov, Alexandre Detappe, Kai Cai, Heather R. Keys, Zarina Brune, Weiwen Ying, Prathapan Thiru, Mairéad Reidy, Guillaume Kugener, Jordan Rossen, Mustafa Kocak, Nora Kory, Aviad Tsherniak, Sandro Santagata, Luke Whitesell, Irene M. Ghobrial, John L. Markley, Susan Lindquist, Todd R. Golub
منشور في 2019Artigo -
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Cancer Vulnerabilities Unveiled by Genomic Loss حسب Deepak Nijhawan, Travis Zack, Yin Ren, Matthew R. Strickland, Rebecca Lamothe, Steven E. Schumacher, Aviad Tsherniak, Henrike C. Besche, Joseph Rosenbluh, Shyemaa Shehata, Glenn S. Cowley, Barbara A. Weir, Alfred L. Goldberg, Jill P. Mesirov, David E. Root, Sangeeta N. Bhatia, Rameen Beroukhim, William C. Hahn
منشور في 2012Artigo
أدوات البحث:
موضوعات ذات صلة
Biology
Genetics
Gene
Computational biology
Cancer
Cancer research
CRISPR
Genome
Cancer cell
Computer science
Cell culture
Medicine
Cell biology
Artificial intelligence
Cancer cell lines
Cell
Phenotype
Bioinformatics
Cas9
Dependency (UML)
Gene expression
RNA
Biochemistry
Function (biology)
Transcription factor
Botany
Cell cycle
Evolutionary biology
Genome editing
Mutant