检索结果 - Aviad Tsherniak

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  1. 1
    Extracting Biological Insights from the Project Achilles Genome-Scale CRISPR Screens in Cancer Cell Lines

    Extracting Biological Insights from the Project Achilles Genome-Scale CRISPR Screens in Cancer Cell Lines 由 Joshua M. Dempster, Jordan Rossen, Mariya Kazachkova, Joshua Pan, Guillaume Kugener, David E. Root, Aviad Tsherniak

    出版 2019
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  2. 2
    Complementary information derived from CRISPR Cas9 mediated gene deletion and suppression

    Complementary information derived from CRISPR Cas9 mediated gene deletion and suppression 由 Joseph Rosenbluh, Han Xu, William F. Harrington, Stanley Gill, Xiaoxing Wang, Francisca Vázquez, David E. Root, Aviad Tsherniak, William C. Hahn

    出版 2017
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  3. 3
    Global computational alignment of tumor and cell line transcriptional profiles

    Global computational alignment of tumor and cell line transcriptional profiles 由 Allison Warren, Yejia Chen, Andrew Jones, Tsukasa Shibue, William C. Hahn, Jesse S. Boehm, Francisca Vázquez, Aviad Tsherniak, James M. McFarland

    出版 2021
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  4. 4
    Chronos: a CRISPR cell population dynamics model

    Chronos: a CRISPR cell population dynamics model 由 Joshua M. Dempster, Isabella Boyle, Francisca Vázquez, David E. Root, Jesse S. Boehm, William C. Hahn, Aviad Tsherniak, James M. McFarland

    出版 2021
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  5. 5
    Chronos: a cell population dynamics model of CRISPR experiments that improves inference of gene fitness effects

    Chronos: a cell population dynamics model of CRISPR experiments that improves inference of gene fitness effects 由 Joshua M. Dempster, Isabella Boyle, Francisca Vázquez, David E. Root, Jesse S. Boehm, William C. Hahn, Aviad Tsherniak, James M. McFarland

    出版 2021
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  6. 6
    Sparse dictionary learning recovers pleiotropy from human cell fitness screens

    Sparse dictionary learning recovers pleiotropy from human cell fitness screens 由 Joshua Pan, Jason J. Kwon, Jessica A. Talamas, Ashir A. Borah, Francisca Vázquez, Jesse S. Boehm, Aviad Tsherniak, Marinka Žitnik, James M. McFarland, William C. Hahn

    出版 2022
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  7. 7
    Functional, chemical genomic, and super-enhancer screening identify sensitivity to cyclin D1/CDK4 pathway inhibition in Ewing sarcoma

    Functional, chemical genomic, and super-enhancer screening identify sensitivity to cyclin D1/CDK4 pathway inhibition in Ewing sarcoma 由 Alyssa L. Kennedy, Mounica Vallurupalli, Liying Chen, Brian D. Crompton, Glenn S. Cowley, Francisca Vázquez, Barbara A. Weir, Aviad Tsherniak, Sudha Parasuraman, Sunkyu Kim, Gabriela Alexe, Kimberly Stegmaier

    出版 2015
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  8. 8
    Predicting Relapse in Patients With Medulloblastoma by Integrating Evidence From Clinical and Genomic Features

    Predicting Relapse in Patients With Medulloblastoma by Integrating Evidence From Clinical and Genomic Features 由 Pablo Tamayo, Yoon-Jae Cho, Aviad Tsherniak, Heidi Greulich, Lauren Ambrogio, Netteke Schouten-van Meeteren, Tianni Zhou, Allen Buxton, Marcel Kool, Matthew Meyerson, Scott L. Pomeroy, Jill P. Mesirov

    出版 2011
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  9. 9
    Multiplex CRISPR/Cas9-Based Genome Editing in Human Hematopoietic Stem Cells Models Clonal Hematopoiesis and Myeloid Neoplasia

    Multiplex CRISPR/Cas9-Based Genome Editing in Human Hematopoietic Stem Cells Models Clonal Hematopoiesis and Myeloid Neoplasia 由 Zuzana Tóthová, John M. Krill-Burger, Katerina D. Popova, Catherine C. Landers, Quinlan Sievers, David Yudovich, Roger Belizaire, Jon C. Aster, Elizabeth A. Morgan, Aviad Tsherniak, Benjamin L. Ebert

    出版 2017
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  10. 10
    Genome-Wide Interrogation of Human Cancers Identifies EGLN1 Dependency in Clear Cell Ovarian Cancers

    Genome-Wide Interrogation of Human Cancers Identifies EGLN1 Dependency in Clear Cell Ovarian Cancers 由 Colles Price, Stanley Gill, Zandra V. Ho, Shawn M. Davidson, Erin Merkel, James M. McFarland, Lisa Leung, Andrew Tang, Maria Kost‐Alimova, Aviad Tsherniak, Oliver Jonas, Francisca Vázquez, William C. Hahn

    出版 2019
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  11. 11
    Partial gene suppression improves identification of cancer vulnerabilities when CRISPR-Cas9 knockout is pan-lethal

    Partial gene suppression improves identification of cancer vulnerabilities when CRISPR-Cas9 knockout is pan-lethal 由 John M. Krill-Burger, Joshua M. Dempster, Ashir A. Borah, Brenton R. Paolella, David E. Root, Todd R. Golub, Jesse S. Boehm, William C. Hahn, James M. McFarland, Francisca Vázquez, Aviad Tsherniak

    出版 2023
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  12. 12
    SWI/SNF-mutant cancers depend on catalytic and non-catalytic activity of EZH2

    SWI/SNF-mutant cancers depend on catalytic and non-catalytic activity of EZH2 由 Kimberly H. Kim, Woojin Kim, Thomas P. Howard, Francisca Vázquez, Aviad Tsherniak, Jennifer N. Wu, Weishan Wang, Jeffrey R. Haswell, Loren D. Walensky, William C. Hahn, Stuart H. Orkin, Charles W.M. Roberts

    出版 2015
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  13. 13
    Interrogation of Mammalian Protein Complex Structure, Function, and Membership Using Genome-Scale Fitness Screens

    Interrogation of Mammalian Protein Complex Structure, Function, and Membership Using Genome-Scale Fitness Screens 由 Joshua Pan, Robin M. Meyers, Brittany C. Michel, Nazar Mashtalir, Ann E. Sizemore, Jonathan N. Wells, Seth H. Cassel, Francisca Vázquez, Barbara A. Weir, William C. Hahn, Joseph A. Marsh, Aviad Tsherniak, Cigall Kadoch

    出版 2018
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  14. 14
    Integrated cross-study datasets of genetic dependencies in cancer

    Integrated cross-study datasets of genetic dependencies in cancer 由 Clare Pacini, Joshua M. Dempster, Isabella Boyle, Emanuel Gonçalves, Hanna Najgebauer, Emre Karakoç, Dieudonne van der Meer, Andrew Barthorpe, Howard Lightfoot, Patricia Jaaks, James M. McFarland, Mathew J. Garnett, Aviad Tsherniak, Francesco Iorio

    出版 2021
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  15. 15
    ATARiS: Computational quantification of gene suppression phenotypes from multisample RNAi screens

    ATARiS: Computational quantification of gene suppression phenotypes from multisample RNAi screens 由 Diane D. Shao, Aviad Tsherniak, Shuba Gopal, Barbara A. Weir, Pablo Tamayo, Nicolas Stransky, Steven E. Schumacher, Travis Zack, Rameen Beroukhim, Levi A. Garraway, Adam A. Margolin, David E. Root, William C. Hahn, Jill P. Mesirov

    出版 2012
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  16. 16
    Improved estimation of cancer dependencies from large-scale RNAi screens using model-based normalization and data integration

    Improved estimation of cancer dependencies from large-scale RNAi screens using model-based normalization and data integration 由 James M. McFarland, Zandra V. Ho, Guillaume Kugener, Joshua M. Dempster, Phillip G. Montgomery, Jordan Bryan, John M. Krill-Burger, Thomas Green, Francisca Vázquez, Jesse S. Boehm, Todd R. Golub, William C. Hahn, David E. Root, Aviad Tsherniak

    出版 2018
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  17. 17
    Genome-scale CRISPR-Cas9 screen identifies druggable dependencies in <i>TP53</i> wild-type Ewing sarcoma

    Genome-scale CRISPR-Cas9 screen identifies druggable dependencies in <i>TP53</i> wild-type Ewing sarcoma 由 Björn Stolte, Amanda Balboni Iniguez, Neekesh V. Dharia, Amanda L. Robichaud, Amy Saur Conway, Ann M. Morgan, Gabriela Alexe, Nathan J. Schauer, Xiaoxi Liu, Gregory H. Bird, Aviad Tsherniak, Francisca Vázquez, Sara J. Buhrlage, Loren D. Walensky, Kimberly Stegmaier

    出版 2018
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  18. 18
    Identification of ADAR1 adenosine deaminase dependency in a subset of cancer cells

    Identification of ADAR1 adenosine deaminase dependency in a subset of cancer cells 由 Hugh Gannon, Tao Zou, Michael K. Kießling, Galen F. Gao, Diana Cai, Peter S. Choi, Alexandru P. Ivan, Ilana Buchumenski, Ashton C. Berger, Jonathan T. Goldstein, Andrew D. Cherniack, Francisca Vázquez, Aviad Tsherniak, Erez Y. Levanon, William C. Hahn, Matthew Meyerson

    出版 2018
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  19. 19
    Mitochondrial metabolism promotes adaptation to proteotoxic stress

    Mitochondrial metabolism promotes adaptation to proteotoxic stress 由 Peter Tsvetkov, Alexandre Detappe, Kai Cai, Heather R. Keys, Zarina Brune, Weiwen Ying, Prathapan Thiru, Mairéad Reidy, Guillaume Kugener, Jordan Rossen, Mustafa Kocak, Nora Kory, Aviad Tsherniak, Sandro Santagata, Luke Whitesell, Irene M. Ghobrial, John L. Markley, Susan Lindquist, Todd R. Golub

    出版 2019
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  20. 20
    Cancer Vulnerabilities Unveiled by Genomic Loss

    Cancer Vulnerabilities Unveiled by Genomic Loss 由 Deepak Nijhawan, Travis Zack, Yin Ren, Matthew R. Strickland, Rebecca Lamothe, Steven E. Schumacher, Aviad Tsherniak, Henrike C. Besche, Joseph Rosenbluh, Shyemaa Shehata, Glenn S. Cowley, Barbara A. Weir, Alfred L. Goldberg, Jill P. Mesirov, David E. Root, Sangeeta N. Bhatia, Rameen Beroukhim, William C. Hahn

    出版 2012
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