Resultados da pesquisa - Arbez, Nicolas

Pridopidine protects neurons from mutant-huntingtin toxicity via the sigma-1 receptor Por Eddings, Chelsy R., Arbez, Nicolas, Akimov, Sergey, Geva, Michal, Hayden, Michael R., Ross, Christopher A.

Obter o texto integral Obter o texto integral Obter o texto integral

Cysteamine Protects Neurons from Mutant Huntingtin Toxicity Por Arbez, Nicolas, Roby, Elaine, Akimov, Sergey, Eddings, Chelsy, Ren, Mark, Wang, Xiaofang, Ross, Christopher A.

Obter o texto integral Obter o texto integral Obter o texto integral

Huntingtin protein interactions altered by polyglutamine expansion as determined by quantitative proteomic analysis Por Ratovitski, Tamara, Chighladze, Ekaterine, Arbez, Nicolas, Boronina, Tatiana, Herbrich, Shelley, Cole, Robert N., Ross, Christopher A.

Obter o texto integral Obter o texto integral Obter o texto integral

Phosphorylation of Mutant Huntingtin at Serine 116 Modulates Neuronal Toxicity Por Watkin, Erin E., Arbez, Nicolas, Waldron-Roby, Elaine, O'Meally, Robert, Ratovitski, Tamara, Cole, Robert N., Ross, Christopher A.

Obter o texto integral Obter o texto integral Obter o texto integral

Post-translational modifications clustering within proteolytic domains decrease mutant huntingtin toxicity Por Arbez, Nicolas, Ratovitski, Tamara, Roby, Elaine, Chighladze, Ekaterine, Stewart, Jacqueline C., Ren, Mark, Wang, Xiaofang, Lavery, Daniel J., Ross, Christopher A.

Obter o texto integral Obter o texto integral Obter o texto integral

Presenilin mediates neuroprotective functions of efnB and BDNF and regulates ligand-induced internalization and metabolism of EphB2 and TrkB receptors Por Gael, Barthet, Julie, Dunys, Shao, Zhiping, Xuan, Zhao, Ren, Ymin, Xu, Jindong, Arbez, Nicolas, Mauger, Gweltas, Bruban, Julien, Georgakopoulos, Anastasios, Shioi, Junichi, Robakis, Nikolaos K.

Obter o texto integral Obter o texto integral Obter o texto integral

G2019S-LRRK2 mutation enhances MPTP-linked Parkinsonism in mice Por Arbez, Nicolas, He, XiaoFei, Huang, Yong, Ren, Mark, Liang, Yideng, Nucifora, Frederick C, Wang, Xiaofang, Pei, Zhong, Tessarolo, Lino, Smith, Wanli W, Ross, Christopher A

Obter o texto integral Obter o texto integral Obter o texto integral

trans-(−)-ϵ-Viniferin Increases Mitochondrial Sirtuin 3 (SIRT3), Activates AMP-activated Protein Kinase (AMPK), and Protects Cells in Models of Huntington Disease Por Fu, Jinrong, Jin, Jing, Cichewicz, Robert H., Hageman, Serena A., Ellis, Trevor K., Xiang, Lan, Peng, Qi, Jiang, Mali, Arbez, Nicolas, Hotaling, Katelyn, Ross, Christopher A., Duan, Wenzhen

Obter o texto integral Obter o texto integral Obter o texto integral

Identification of Novel Potentially Toxic Oligomers Formed in Vitro from Mammalian-derived Expanded huntingtin Exon-1 Protein Por Nucifora, Leslie G., Burke, Kathleen A., Feng, Xia, Arbez, Nicolas, Zhu, Shanshan, Miller, Jason, Yang, Guocheng, Ratovitski, Tamara, Delannoy, Michael, Muchowski, Paul J., Finkbeiner, Steven, Legleiter, Justin, Ross, Christopher A., Poirier, Michelle A.

Obter o texto integral Obter o texto integral Obter o texto integral

N6-Furfuryladenine is protective in Huntington’s disease models by signaling huntingtin phosphorylation Por Bowie, Laura E., Maiuri, Tamara, Alpaugh, Melanie, Gabriel, Michelle, Arbez, Nicolas, Galleguillos, Danny, Hung, Claudia L. K., Patel, Shreya, Xia, Jianrun, Hertz, Nicholas T., Ross, Christopher A., Litchfield, David W., Sipione, Simonetta, Truant, Ray

Obter o texto integral Obter o texto integral Obter o texto integral

ATXN2-AS, a Gene Antisense to ATXN2, Is Associated with Spinocerebellar Ataxia Type 2 and Amyotrophic Lateral Sclerosis Por Li, Pan P., Sun, Xin, Xia, Guangbin, Arbez, Nicolas, Paul, Sharan, Zhu, Shanshan, Peng, H. Benjamin, Ross, Christopher A., Koeppen, Arnulf H., Margolis, Russell L., Pulst, Stefan M., Ashizawa, Tetsuo, Rudnicki, Dobrila D.

Obter o texto integral Obter o texto integral Obter o texto integral

RNA Toxicity and Perturbation of rRNA Processing in Spinocerebellar Ataxia Type 2 Por Li, Pan P., Moulick, Roumita, Feng, Hongxuan, Sun, Xin, Arbez, Nicolas, Jin, Jing, Marque, Leonard O., Hedglen, Erin, Chan, H.Y. Edwin, Ross, Christopher A., Pulst, Stefan M., Margolis, Russell L., Woodson, Sarah, Rudnicki, Dobrila D.

Obter o texto integral Obter o texto integral Obter o texto integral

Post-Translational Modifications (PTMs), Identified on Endogenous Huntingtin, Cluster within Proteolytic Domains between HEAT Repeats Por Ratovitski, Tamara, O’Meally, Robert N., Jiang, Mali, Chaerkady, Raghothama, Chighladze, Ekaterine, Stewart, Jacqueline C., Wang, Xiaofang, Arbez, Nicolas, Roby, Elaine, Alexandris, Athanasios, Duan, Wenzhen, Vijayvargia, Ravi, Seong, Ihn Sik, Lavery, Daniel J., Cole, Robert N., Ross, Christopher A.

Obter o texto integral Obter o texto integral Obter o texto integral

TBK1 phosphorylates mutant Huntingtin and suppresses its aggregation and toxicity in Huntington's disease models Por Hegde, Ramanath Narayana, Chiki, Anass, Petricca, Lara, Martufi, Paola, Arbez, Nicolas, Mouchiroud, Laurent, Auwerx, Johan, Landles, Christian, Bates, Gillian P, Singh‐Bains, Malvindar K, Dragunow, Mike, Curtis, Maurice A, Faull, Richard LM, Ross, Christopher A, Caricasole, Andrea, Lashuel, Hilal A

Obter o texto integral Obter o texto integral Obter o texto integral

Immortalized striatal precursor neurons from Huntington’s disease patient-derived iPS cells as a platform for target identification and screening for experimental therapeutics Por Akimov, Sergey S, Jiang, Mali, Kedaigle, Amanda J, Arbez, Nicolas, Marque, Leonard O, Eddings, Chelsy R, Ranum, Paul T, Whelan, Emma, Tang, Anthony, Wang, Ronald, DeVine, Lauren R, Talbot, Conover C, Cole, Robert N, Ratovitski, Tamara, Davidson, Beverly L, Fraenkel, Ernest, Ross, Christopher A

Obter o texto integral Obter o texto integral Obter o texto integral

Ubiqutination via K27 and K29 chains signals aggregation and neuronal protection of LRRK2 by WSB1 Por Nucifora, Frederick C., Nucifora, Leslie G., Ng, Chee-Hoe, Arbez, Nicolas, Guo, Yajuan, Roby, Elaine, Shani, Vered, Engelender, Simone, Wei, Dong, Wang, Xiao-Fang, Li, Tianxia, Moore, Darren J., Pletnikova, Olga, Troncoso, Juan C., Sawa, Akira, Dawson, Ted M., Smith, Wanli, Lim, Kah-Leong, Ross, Christopher A.

Obter o texto integral Obter o texto integral Obter o texto integral

Nemo-like kinase reduces mutant huntingtin levels and mitigates Huntington’s disease Por Jiang, Mali, Zhang, Xiaoyan, Liu, Hongshuai, LeBron, Jared, Alexandris, Athanasios, Peng, Qi, Gu, Hao, Yang, Fanghan, Li, Yuchen, Wang, Ruiling, Hou, Zhipeng, Arbez, Nicolas, Ren, Qianwei, Dong, Jen-Li, Whela, Emma, Wang, Ronald, Ratovitski, Tamara, Troncoso, Juan C, Mori, Susumu, Ross, Christopher A, Lim, Janghoo, Duan, Wenzhen

Obter o texto integral Obter o texto integral Obter o texto integral

Bexarotene-activated PPARδ promotes neuroprotection by restoring bioenergetic and quality control homeostasis Por Dickey, Audrey S., Sanchez, Dafne N., Arreola, Martin, Sampat, Kunal R., Fan, Weiwei, Arbez, Nicolas, Akimov, Sergey, Van Kanegan, Michael J., Ohnishi, Kohta, Gilmore-Hall, Stephen K., Flores, April L., Nguyen, Janice M., Lomas, Nicole, Hsu, Cynthia L., Lo, Donald C., Ross, Christopher A., Masliah, Eliezer, Evans, Ronald M., La Spada, Albert R.

Obter o texto integral Obter o texto integral Obter o texto integral

Mutant Huntingtin Disrupts the Nuclear Pore Complex Por Grima, Jonathan C., Daigle, J. Gavin, Arbez, Nicolas, Cunningham, Kathleen C., Zhang, Ke, Ochaba, Joseph, Geater, Charlene, Morozko, Eva, Stocksdale, Jennifer, Glatzer, Jenna C., Pham, Jacqueline T., Ahmed, Ishrat, Peng, Qi, Wadhwa, Harsh, Pletnikova, Olga, Troncoso, Juan C., Duan, Wenzhen, Snyder, Solomon H., Ranum, Laura P.W., Thompson, Leslie M., Lloyd, Thomas E., Ross, Christopher A., Rothstein, Jeffrey D.

Obter o texto integral Obter o texto integral Obter o texto integral

Neuroprotective role of SIRT1 in mammalian models of Huntington’s disease through activation of multiple SIRT1 targets Por Jiang, Mali, Wang, Jiawei, Fu, Jinrong, Du, Lin, Jeong, Hyun-Kyung, West, Tim, Xiang, Lan, Peng, Qi, Hou, Zhipeng, Cai, Huan, Seredenin, Tamara, Arbez, Nicolas, Zhu, Shanshan, Sommers, Katherine, Qian, Jennifer, Zhang, Jiangyang, Mori, Susumu, Yang, X. William, Tamashiro, Kellie L. K., Aja, Susan, Moran, Timothy H., Luthi-Carter, Ruth, Martin, Bronwen, Maudsley, Stuart, Mattson, Mark P., Cichewicz, Robert H., Ross, Christopher A., Holtzman, David M., Krainc, Dimitri, Duan, Wenzhen

Obter o texto integral Obter o texto integral Obter o texto integral