Resultados da pesquisa - Anthony W. Tolcher
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1
Antibody drug conjugates: lessons from 20 years of clinical experience Por Anthony W. Tolcher
Publicado em 2016Revisão -
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The Evolution of Antibody-Drug Conjugates: A Positive Inflexion Point Por Anthony W. Tolcher
Publicado em 2020Artigo -
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Synergistic chemosensitization and inhibition of progression to androgen independence by antisense Bcl-2 oligodeoxynucleotide and paclitaxel in the LNCaP prostate tumor model Por Suet Yi Leung, Hideaki Miyake, Tobias Zellweger, Anthony W. Tolcher, Martin Gleave
Publicado em 2001Artigo -
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A phase I open-label study evaluating the cardiovascular safety of sorafenib in patients with advanced cancer Por Anthony W. Tolcher, Leonard J. Appleman, Geoffrey I. Shapiro, Alain C. Mita, Frank Cihon, Arthur Mazzu, P. R. Sundaresan
Publicado em 2010Artigo -
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Phase I study of the CD40 agonist antibody CP-870,893 combined with carboplatin and paclitaxel in patients with advanced solid tumors Por Robert H. Vonderheide, Jennifer M. Burg, Rosemarie Mick, Jennifer A. Trosko, Dongguang Li, M. Naveed Shaik, Anthony W. Tolcher, Omid Hamid
Publicado em 2013Artigo -
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A phase 1 dose escalation and expansion study of Tarextumab (OMP-59R5) in patients with solid tumors Por David C. Smith, Rashmi Chugh, Amita Patnaik, Kyriakos P. Papadopoulos, Min Wang, Ann M. Kapoun, Lu Xu, Jakob Dupont, Robert Stagg, Anthony W. Tolcher
Publicado em 2018Artigo -
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Efficacy and Safety of the MDM2–p53 Antagonist Brigimadlin (BI 907828) in Patients with Advanced Biliary Tract Cancer: A Case Series Por Noboru Yamamoto, Anthony W. Tolcher, Navid Hafez, Iwona Ługowska, Rodryg Ramlau, Teresa Macarulla, Junxian Geng, Jian Li, Michael Teufel, Angela Märten, Patricia LoRusso
Publicado em 2024Artigo -
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Correlating animal and human phase Ia/Ib clinical data with CALAA-01, a targeted, polymer-based nanoparticle containing siRNA Por Jonathan E. Zuckerman, Ismael Gritli, Anthony W. Tolcher, Jeremy D. Heidel, Dean Lim, Robert J. Morgan, Bartosz Chmielowski, Antoni Ribas, Mark E. Davis, Yun Yen
Publicado em 2014Artigo -
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Phase I Study of GS-3583, an FMS-like Tyrosine Kinase 3 Agonist Fc Fusion Protein, in Patients with Advanced Solid Tumors Por Anthony W. Tolcher, Joshua Brody, Nishanthan Rajakumaraswamy, Michelle Kuhne, Torsten Trowe, Anees M. Dauki, Shantheri Pai, Ling Han, Kai-Wen Lin, Michael Petrarca, Shivaani Kummar
Publicado em 2024Artigo -
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Phase I dose-escalation study of EZN-2208 (PEG-SN38), a novel conjugate of poly(ethylene) glycol and SN38, administered weekly in patients with advanced cancer Por Amita Patnaik, Kyriakos P. Papadopoulos, Anthony W. Tolcher, Muralidhar Beeram, Saı̈k Urien, Larry J. Schaaf, Sanaa Tahiri, Tanios Bekaii‐Saab, François Lokiec, Keyvan Rezaï, Aby Buchbinder
Publicado em 2013Artigo -
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Evidence of RNAi in humans from systemically administered siRNA via targeted nanoparticles Por Mark E. Davis, Jonathan E. Zuckerman, Chung Hang Jonathan Choi, David B. Seligson, Anthony W. Tolcher, Christopher A. Alabi, Yun Yen, Jeremy D. Heidel, Antoni Ribas
Publicado em 2010Artigo -
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Volociximab, a Chimeric Monoclonal Antibody that Specifically Binds α5β1 Integrin: A Phase I, Pharmacokinetic, and Biological Correlative Study Por Alejandro D. Ricart, Anthony W. Tolcher, Glenn Liu, Kyle D. Holen, Garry Schwartz, Mark R. Albertini, Geoffrey R. Weiss, Salim Yazji, Chee M. Ng, George Wilding
Publicado em 2008Artigo -
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First-in-Human Study of AMG 820, a Monoclonal Anti-Colony-Stimulating Factor 1 Receptor Antibody, in Patients with Advanced Solid Tumors Por Kyriakos P. Papadopoulos, Larry Gluck, Lainie P. Martin, Anthony J. Olszanski, Anthony W. Tolcher, Gataree Ngarmchamnanrith, Erik Rasmussen, Benny Amore, Dirk Nagorsen, John S. Hill, Joe Stephenson
Publicado em 2017Artigo -
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First-in-Human Study of the Ataxia Telangiectasia and Rad3-Related (ATR) Inhibitor Tuvusertib (M1774) as Monotherapy in Patients with Solid Tumors Por Timothy A. Yap, Anthony W. Tolcher, Ruth Plummer, Jatinder Kaur Mukker, Marta Enderlin, Christine Hicking, Thomas Grombacher, Giuseppe Locatelli, Zoltán Szűcs, Ioannis Gounaris, Johann S. de Bono
Publicado em 2024Artigo -
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Phase I ficlatuzumab monotherapy or with erlotinib for refractory advanced solid tumours and multiple myeloma Por Amita Patnaik, Glen J. Weiss, K. Papadopoulos, Craig C. Hofmeister, Raoul Tibes, Anthony W. Tolcher, Robin Isaacs, J. Jac, May Han, Francis Payumo, Monette Cotreau, Rajesh Ramanathan
Publicado em 2014Artigo -
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A Phase I Study of ASTX660, an Antagonist of Inhibitors of Apoptosis Proteins, in Adults with Advanced Cancers or Lymphoma Por Monica Mita, Patricia LoRusso, Kyriakos P. Papadopoulos, Michael S. Gordon, Alain C. Mita, Roberta Ferraldeschi, Harold Keer, Aram Oganesian, Xiang Yao Su, Simone Jueliger, Anthony W. Tolcher
Publicado em 2020Artigo -
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Phase I Safety, Pharmacokinetic and Pharmacodynamic Evaluation of the Vascular Disrupting Agent Ombrabulin (AVE8062) in Patients with Advanced Solid Tumors Por Cristiana Sessa, Patricia LoRusso, Anthony W. Tolcher, Françoise Farace, Nathalie Lassau, Angelo Delmonte, Antonio Braghetti, Rastislav Bahleda, Patrick Cohen, Marie Hospitel, Christine Veyrat‐Follet, Jean‐Charles Soria
Publicado em 2013Artigo
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Assuntos relacionados
Medicine
Internal medicine
Pharmacology
Cancer
Adverse effect
Pharmacokinetics
Oncology
Gastroenterology
Pharmacodynamics
Biology
Nausea
Tolerability
Cancer research
Toxicity
Chemotherapy
Immunology
Antibody
Biochemistry
Chemistry
Neutropenia
Phases of clinical research
Receptor
Vomiting
Breast cancer
Colorectal cancer
Gene
Genetics
Kinase
MAPK/ERK pathway
Monoclonal antibody