Search Results - Anne Fassl

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  1. 1
    CDK4 and CDK6 kinases: From basic science to cancer therapy

    CDK4 and CDK6 kinases: From basic science to cancer therapy by Anne Fassl, Yan Geng, Piotr Siciński

    Published 2022
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  2. 2
    Targeting Aberrant FGFR Signaling to Overcome CDK4/6 Inhibitor Resistance in Breast Cancer

    Targeting Aberrant FGFR Signaling to Overcome CDK4/6 Inhibitor Resistance in Breast Cancer by Navid Sobhani, Anne Fassl, Giuseppina Mondani, Daniele Generali, Tobias Otto

    Published 2021
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  3. 3
    MicroRNA-210 induces apoptosis in colorectal cancer via induction of reactive oxygen

    MicroRNA-210 induces apoptosis in colorectal cancer via induction of reactive oxygen by Katrin E. Tagscherer, Anne Fassl, Tabea Sinkovic, Jutta Richter, Sabrina Schecher, Stephan Macher‐Goeppinger, Wilfried Roth

    Published 2016
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  4. 4
    Apoptosis-based treatment of glioblastomas with ABT-737, a novel small molecule inhibitor of Bcl-2 family proteins

    Apoptosis-based treatment of glioblastomas with ABT-737, a novel small molecule inhibitor of Bcl-2 family proteins by Katrin E. Tagscherer, Anne Fassl, Benito Campos, Mohammad Farhadi, Alwin Kraemer, Barbara C. Böck, Stephan Macher‐Goeppinger, Bernhard Radlwimmer, O. D. Wiestler, Christel Herold‐Mende, Wilfried Roth

    Published 2008
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  5. 5
    Danger Signaling Protein HMGB1 Induces a Distinct Form of Cell Death Accompanied by Formation of Giant Mitochondria

    Danger Signaling Protein HMGB1 Induces a Distinct Form of Cell Death Accompanied by Formation of Giant Mitochondria by Georg Gdynia, Martina Keith, Jürgen Kopitz, Marion Bergmann, Anne Fassl, Alexander N.R. Weber, Julie George, Tim Kees, Hans-Walter Zentgraf, Otmar D. Wiestler, Peter Schirmacher, Wilfried Roth

    Published 2010
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  6. 6
    Cell cycle-targeting microRNAs promote differentiation by enforcing cell-cycle exit

    Cell cycle-targeting microRNAs promote differentiation by enforcing cell-cycle exit by Tobias Otto, Sheyla V. Candido, Mary Pilarz, Ewa Sicińska, Roderick T. Bronson, Michaela Bowden, Iga A. Lachowicz, Kristin A. Mulry, Anne Fassl, Richard C. Han, Emmanuelle Jecrois, Piotr Siciński

    Published 2017
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  7. 7
    Inhibition of CK1ε potentiates the therapeutic efficacy of CDK4/6 inhibitor in breast cancer

    Inhibition of CK1ε potentiates the therapeutic efficacy of CDK4/6 inhibitor in breast cancer by Fabin Dang, Li Nie, Jin Zhou, Kouhei Shimizu, Chen Chu, Zhong Wu, Anne Fassl, Shizhong Ke, Yuangao Wang, Jinfang Zhang, Tao Zhang, Zhenbo Tu, Hiroyuki Inuzuka, Piotr Siciński, Adam J. Bass, Wenyi Wei

    Published 2021
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  8. 8
    Small-molecule studies identify CDK8 as a regulator of IL-10 in myeloid cells

    Small-molecule studies identify CDK8 as a regulator of IL-10 in myeloid cells by Liv Johannessen, Thomas B. Sundberg, Daniel J. O’Connell, Raivo Kolde, James Berstler, Katelyn Billings, Bernard Khor, Brinton Seashore‐Ludlow, Anne Fassl, Caitlin Russell, Isabel Latorre, Baishan Jiang, Daniel B. Graham, José R. Perez, Piotr Siciński, Andrew J. Phillips, Stuart L. Schreiber, Nathanael S. Gray, Alykhan F. Shamji, Ramnik J. Xavier

    Published 2017
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  9. 9
    Acquired resistance to combined BET and CDK4/6 inhibition in triple-negative breast cancer

    Acquired resistance to combined BET and CDK4/6 inhibition in triple-negative breast cancer by Jennifer Y. Ge, Shaokun Shu, Mijung Kwon, Bojana Jovanović, Katherine Murphy, Anushree C. Gulvady, Anne Fassl, Anne Trinh, Yanan Kuang, Grace A. Heavey, Adrienne Luoma, Cloud P. Paweletz, Aaron R. Thorner, Kai W. Wucherpfennig, Jun Qi, Myles Brown, Piotr Siciński, Thomas O. McDonald, David Pellman, Franziska Michor, Kornélia Polyák

    Published 2020
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  10. 10
    MED12 Regulates HSC-Specific Enhancers Independently of Mediator Kinase Activity to Control Hematopoiesis

    MED12 Regulates HSC-Specific Enhancers Independently of Mediator Kinase Activity to Control Hematopoiesis by Beatriz Aranda-Orgillés, Ricardo Saldaña-Meyer, Eric Wang, Eirini Trompouki, Anne Fassl, Stephanie Lau, Jasper Mullenders, Pedro P. Rocha, Ramya Raviram, María Guillamot, María Sánchez-Díaz, Kun Wang, Clarisse Kayembe, Nan Zhang, Leonela Amoasii, Avik Choudhuri, Jane A. Skok, Markus Schöber, Danny Reinberg, Piotr Siciński, Heinrich Schrewe, Aristotelis Tsirigos, Leonard I. Zon, Iannis Aifantis

    Published 2016
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  11. 11
    Cell-Cycle-Targeting MicroRNAs as Therapeutic Tools against Refractory Cancers

    Cell-Cycle-Targeting MicroRNAs as Therapeutic Tools against Refractory Cancers by Per Hydbring, Yinan Wang, Anne Fassl, Xiaoting Li, Verónica Matía, Tobias Otto, Yoon Jong Choi, Katharine E. Sweeney, Jan M. Suski, Hao Yin, Roman L. Bogorad, Shom Goel, Haluk Yuzugullu, Kevin Kauffman, Junghoon Yang, Chong Jin, Yingxiang Li, Davide Floris, Richard S. Swanson, Kimmie Ng, Ewa Sicińska, Lars Anders, Jean J. Zhao, Kornélia Polyák, Daniel G. Anderson, Cheng Li, Piotr Siciński

    Published 2017
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  12. 12
    Increased lysosomal biomass is responsible for the resistance of triple-negative breast cancers to CDK4/6 inhibition

    Increased lysosomal biomass is responsible for the resistance of triple-negative breast cancers to CDK4/6 inhibition by Anne Fassl, Christopher T. Brain, Monther Abu-Remaileh, Iga Stukan, Deborah Butter, Piotr Stępień, Avery Feit, Johann S. Bergholz, Wojciech Michowski, Tobias Otto, Qing Sheng, Alice Loo, Walter Michael, Ralph Tiedt, Carmine De Angelis, Rachel Schiff, Baishan Jiang, Bojana Jovanović, Karolina Nowak, Maria Ericsson, Michael D. Cameron, Nathanael S. Gray, Deborah Dillon, Jean J. Zhao, David M. Sabatini, Rinath Jeselsohn, Myles Brown, Kornélia Polyák, Piotr Siciński

    Published 2020
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  13. 13
    KDM5 Histone Demethylase Activity Links Cellular Transcriptomic Heterogeneity to Therapeutic Resistance

    KDM5 Histone Demethylase Activity Links Cellular Transcriptomic Heterogeneity to Therapeutic Resistance by Kunihiko Hinohara, Hua‐Jun Wu, Sébastien Vigneau, Thomas O. McDonald, Kyomi J. Igarashi, Kimiyo N. Yamamoto, Thomas Madsen, Anne Fassl, Shawn B. Egri, Malvina Papanastasiou, Lina Ding, Guillermo Peluffo, Ofir Cohen, Stephen C. Kales, Madhu Lal‐Nag, Ganesha Rai, David J. Maloney, Ajit Jadhav, Anton Simeonov, Nikhil Wagle, Myles Brown, Alexander Meissner, Piotr Siciński, Jacob D. Jaffe, Rinath Jeselsohn, Alexander A. Gimelbrant, Franziska Michor, Kornélia Polyák

    Published 2018
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  14. 14
    KDM5 Histone Demethylase Activity Links Cellular Transcriptomic Heterogeneity to Therapeutic Resistance

    KDM5 Histone Demethylase Activity Links Cellular Transcriptomic Heterogeneity to Therapeutic Resistance by Kunihiko Hinohara, Hua‐Jun Wu, Sébastien Vigneau, Thomas O. McDonald, Kyomi J. Igarashi, Kimiyo N. Yamamoto, Thomas Madsen, Anne Fassl, Shawn B. Egri, Malvina Papanastasiou, Lina Ding, Guillermo Peluffo, Ofir Cohen, Stephen C. Kales, Madhu Lal‐Nag, Ganesha Rai, David J. Maloney, Ajit Jadhav, Anton Simeonov, Nikhil Wagle, Myles Brown, Alexander Meissner, Piotr Siciński, Jacob D. Jaffe, Rinath Jeselsohn, Alexander A. Gimelbrant, Franziska Michor, Kornélia Polyák

    Published 2019
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  15. 15
    Cdk1 Controls Global Epigenetic Landscape in Embryonic Stem Cells

    Cdk1 Controls Global Epigenetic Landscape in Embryonic Stem Cells by Wojciech Michowski, Joel M. Chick, Chen Chu, Aleksandra Kołodziejczyk, Yichen Wang, Jan M. Suski, Brian J. Abraham, Lars Anders, Daniel S. Day, Lukas Manuel Dunkl, Mitchell Li Cheong Man, Tian Zhang, Phatthamon Laphanuwat, Nickolas A. Bacon, Lijun Liu, Anne Fassl, Samanta Sharma, Tobias Otto, Emanuelle Jecrois, Richard C. Han, Katharine E. Sweeney, Samuele Marro, Marius Wernig, Yan Geng, Alan M Moses, Cheng Li, Steven P. Gygi, Richard A. Young, Piotr Siciński

    Published 2020
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  16. 16
    JAK–STAT Signaling in Inflammatory Breast Cancer Enables Chemotherapy-Resistant Cell States

    JAK–STAT Signaling in Inflammatory Breast Cancer Enables Chemotherapy-Resistant Cell States by Laura E. Stevens, Guillermo Peluffo, Xintao Qiu, Daniel Temko, Anne Fassl, Zheqi Li, Anne Trinh, Marco Seehawer, Bojana Jovanović, Maša Alečković, Callahan M. Wilde, Renee C. Geck, Shaokun Shu, Natalie L. Kingston, Nicholas W. Harper, Vanessa Almendro, Alanna L. Pyke, Shawn B. Egri, Malvina Papanastasiou, Kendell Clement, Ningxuan Zhou, Sarah R. Walker, Jacqueline Salas, So Yeon Park, David A. Frank, Alexander Meissner, Jacob D. Jaffe, Piotr Siciński, Alex Toker, Franziska Michor, Henry W. Long, Beth Overmoyer, Kornélia Polyák

    Published 2022
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  17. 17
    Cyclin C is a haploinsufficient tumour suppressor

    Cyclin C is a haploinsufficient tumour suppressor by Na Li, Anne Fassl, Joel M. Chick, Hiroyuki Inuzuka, Xiaoyu Li, Marc R. Mansour, Lijun Liu, Haizhen Wang, Bryan H. King, Shavali Shaik, Alejandro Gutiérrez, Alban Ordureau, Tobias Otto, Taras Kreslavsky, Lukas Baitsch, Leah Bury, Clifford A. Meyer, Nan Rosemary Ke, Kristin A. Mulry, Michael Kluk, Moni Roy, Sunkyu Kim, Xiaowu Zhang, Yan Geng, Agnieszka Zagożdżon, Sarah Jenkinson, Rosemary E. Gale, David C. Linch, Jean J. Zhao, Charles G. Mullighan, J. Wade Harper, Jon C. Aster, Iannis Aifantis, Harald von Boehmer, Steven P. Gygi, Wenyi Wei, A. Thomas Look, Piotr Siciński

    Published 2014
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  18. 18
    Perturbed myoepithelial cell differentiation in BRCA mutation carriers and in ductal carcinoma in situ

    Perturbed myoepithelial cell differentiation in BRCA mutation carriers and in ductal carcinoma in situ by Lina Ding, Ying Su, Anne Fassl, Kunihiko Hinohara, Xintao Qiu, Nicholas W. Harper, Sung Jin Huh, Noga Bloushtain-Qimron, Bojana Jovanović, Muhammad B. Ekram, Xiaoyuan Zi, William C. Hines, Maša Alečković, Carlos Gil Del Alcazar, Ryan J. Caulfield, Dennis M. Bonal, Quang-Dé Nguyen, Vanessa F. Merino, Sibgat Choudhury, Gabrielle Ethington, Laura Panos, Michael D. Grant, William Herlihy, Alfred Au, Gedge D. Rosson, Pedram Argani, Andrea L. Richardson, Deborah Dillon, D. Craig Allred, Kirsten Babski, Elizabeth Min Hui Kim, Charles H. McDonnell, Jon Wagner, Ron Rowberry, Kristie Bobolis, Celina G. Kleer, E. Shelley Hwang, Joanne L. Blum, Simona Cristea, Piotr Siciński, Rong Fan, Henry W. Long, Saraswati Sukumar, So Yeon Park, Judy E. Garber, Mina J. Bissell, Jun Yao, Kornélia Polyák

    Published 2019
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