نتائج البحث - Anna Rodina

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  1. 1
    Heat shock protein 90 in neurodegenerative diseases

    Heat shock protein 90 in neurodegenerative diseases حسب Wenjie Luo, Weilin Sun, Tony Taldone, Anna Rodina, Gabriela Chiosis

    منشور في 2010
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  2. 2
    Chaperome heterogeneity and its implications for cancer study and treatment

    Chaperome heterogeneity and its implications for cancer study and treatment حسب Tai Wang, Anna Rodina, Mark Dunphy, Adriana Corben, Shanu Modi, Mónica L. Guzmán, D.T. Gewirth, Gabriela Chiosis

    منشور في 2018
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  3. 3
    How aberrant N-glycosylation can alter protein functionality and ligand binding: An atomistic view

    How aberrant N-glycosylation can alter protein functionality and ligand binding: An atomistic view حسب Matteo Castelli, Pengrong Yan, Anna Rodina, Chander Singh Digwal, Palak Panchal, Gabriela Chiosis, Elisabetta Moroni, Giorgio Colombo

    منشور في 2023
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  4. 4
    Design, synthesis, and evaluation of small molecule Hsp90 probes

    Design, synthesis, and evaluation of small molecule Hsp90 probes حسب Tony Taldone, Danuta Zatorska, Pallav D. Patel, Hongliang Zong, Anna Rodina, James H. Ahn, Kamalika Moulick, Mónica L. Guzmán, Gabriela Chiosis

    منشور في 2011
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  5. 5
    Roles of heat-shock protein 90 in maintaining and facilitating the neurodegenerative phenotype in tauopathies

    Roles of heat-shock protein 90 in maintaining and facilitating the neurodegenerative phenotype in tauopathies حسب Wenjie Luo, Fei Dou, Anna Rodina, Sophorn Chip, Joungnam Kim, Qi Zhao, Kamalika Moulick, Julia Aguirre, Nian Wu, Paul Greengard, Gabriela Chiosis

    منشور في 2007
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  6. 6
    Experimental and Structural Testing Module to Analyze Paralogue-Specificity and Affinity in the Hsp90 Inhibitors Series

    Experimental and Structural Testing Module to Analyze Paralogue-Specificity and Affinity in the Hsp90 Inhibitors Series حسب Tony Taldone, Pallav D. Patel, Maulik Patel, Hardik J. Patel, Christopher E. B. Evans, Anna Rodina, Stefan O. Ochiana, Smit Shah, Mohammad Uddin, D.T. Gewirth, Gabriela Chiosis

    منشور في 2013
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  7. 7
    Heat Shock Protein 70 Inhibitors. 1. 2,5′-Thiodipyrimidine and 5-(Phenylthio)pyrimidine Acrylamides as Irreversible Binders to an Allosteric Site on Heat Shock Protein 70

    Heat Shock Protein 70 Inhibitors. 1. 2,5′-Thiodipyrimidine and 5-(Phenylthio)pyrimidine Acrylamides as Irreversible Binders to an Allosteric Site on Heat Shock Protein 70 حسب Yanlong Kang, Tony Taldone, Hardik J. Patel, Pallav D. Patel, Anna Rodina, Alexander Gozman, Ronnie Maharaj, Cristina C. Clement, Maulik Patel, Jeffrey L. Brodsky, Jason C. Young, Gabriela Chiosis

    منشور في 2014
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  8. 8
    Heat Shock Protein 70 Inhibitors. 2. 2,5′-Thiodipyrimidines, 5-(Phenylthio)pyrimidines, 2-(Pyridin-3-ylthio)pyrimidines, and 3-(Phenylthio)pyridines as Reversible Binders to an Allosteric Site on Heat Shock Protein 70

    Heat Shock Protein 70 Inhibitors. 2. 2,5′-Thiodipyrimidines, 5-(Phenylthio)pyrimidines, 2-(Pyridin-3-ylthio)pyrimidines, and 3-(Phenylthio)pyridines as Reversible Binders to an All... حسب Tony Taldone, Yanlong Kang, Hardik J. Patel, Maulik Patel, Pallav D. Patel, Anna Rodina, Yogita Patel, Alexander Gozman, Ronnie Maharaj, Cristina C. Clement, Alvin Lu, Jason C. Young, Gabriela Chiosis

    منشور في 2014
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  9. 9
    A Chemical Biology Approach to the Chaperome in Cancer—HSP90 and Beyond

    A Chemical Biology Approach to the Chaperome in Cancer—HSP90 and Beyond حسب Tony Taldone, Tai Wang, Anna Rodina, Nagavarakishore Pillarsetty, Chander Singh Digwal, Sahil Sharma, Pengrong Yan, Suhasini Joshi, Piyusha P. Pagare, Alexander Bolaender, Gail J. Roboz, Mónica L. Guzmán, Gabriela Chiosis

    منشور في 2019
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  10. 10
    Targeting the Hsp90-associated viral oncoproteome in gammaherpesvirus-associated malignancies

    Targeting the Hsp90-associated viral oncoproteome in gammaherpesvirus-associated malignancies حسب Utthara Nayar, Pin Lü, Rebecca Goldstein, Jelena Vider, Gianna Ballon, Anna Rodina, Tony Taldone, Hediye Erdjument‐Bromage, Max Chomet, Ronald Blasberg, Ari Melnick, Leandro Cerchietti, Gabriela Chiosis, Y. Lynn Wang, Ethel Cesarman

    منشور في 2013
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  11. 11
    Gene expression signature-based chemical genomic prediction identifies a novel class of HSP90 pathway modulators

    Gene expression signature-based chemical genomic prediction identifies a novel class of HSP90 pathway modulators حسب Haley Hieronymus, Justin Lamb, Kenneth N. Ross, Xiao Peng, Cristina C. Clement, Anna Rodina, M. Ángela Nieto, Jinyan Du, Kimberly Stegmaier, Srilakshmi M. Raj, Katherine N. Maloney, Jon Clardy, William C. Hahn, Gabriela Chiosis, Todd R. Golub

    منشور في 2006
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  12. 12
    Identification of an Allosteric Pocket on Human Hsp70 Reveals a Mode of Inhibition of This Therapeutically Important Protein

    Identification of an Allosteric Pocket on Human Hsp70 Reveals a Mode of Inhibition of This Therapeutically Important Protein حسب Anna Rodina, Pallav D. Patel, Yanlong Kang, Yogita Patel, Imad Baaklini, Michael Wong, Tony Taldone, Pengrong Yan, Chenghua Yang, Ronnie Maharaj, Alexander Gozman, Maulik Patel, Hardik Patel, William J. Chirico, Hediye Erdjument‐Bromage, Tanaji T. Talele, Jason C. Young, Gabriela Chiosis

    منشور في 2013
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  13. 13
    Inhibition of Hsp90 Suppresses PI3K/AKT/mTOR Signaling and Has Antitumor Activity in Burkitt Lymphoma

    Inhibition of Hsp90 Suppresses PI3K/AKT/mTOR Signaling and Has Antitumor Activity in Burkitt Lymphoma حسب Lisa Giulino‐Roth, Herman J. van Besien, Tanner C. Dalton, Jennifer Totonchy, Anna Rodina, Tony Taldone, Alexander Bolaender, Hediye Erdjument‐Bromage, Jouliana Sadek, Amy Chadburn, Matthew J. Barth, Filemon S. Dela Cruz, Allison R. Rainey, Andrew L. Kung, Gabriela Chiosis, Ethel Cesarman

    منشور في 2017
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  14. 14
    Hsp90 inhibitor PU-H71, a multimodal inhibitor of malignancy, induces complete responses in triple-negative breast cancer models

    Hsp90 inhibitor PU-H71, a multimodal inhibitor of malignancy, induces complete responses in triple-negative breast cancer models حسب Eloisi Caldas-Lopes, Leandro Cerchietti, James H. Ahn, Cristina C. Clement, Ana I. Robles, Anna Rodina, Kamalika Moulick, Tony Taldone, Alexander Gozman, Yunke Guo, Nian Wu, Elisa de Stanchina, Julie R. White, Steven S. Gross, Yuliang Ma, Lyuba Varticovski, Ari Melnick, Gabriela Chiosis

    منشور في 2009
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  15. 15
    HSP90 is a therapeutic target in JAK2-dependent myeloproliferative neoplasms in mice and humans

    HSP90 is a therapeutic target in JAK2-dependent myeloproliferative neoplasms in mice and humans حسب Sachie Marubayashi, Priya Koppikar, Tony Taldone, Omar Abdel‐Wahab, Nathan West, Neha Bhagwat, Eloisi Caldas-Lopes, Kenneth N. Ross, Mithat Gönen, Alex Gozman, James H. Ahn, Anna Rodina, Ouathek Ouerfelli, Guangbin Yang, Cyrus V. Hedvat, James E. Bradner, Gabriela Chiosis, Ross L. Levine

    منشور في 2010
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  16. 16
    A Hyperactive Signalosome in Acute Myeloid Leukemia Drives Addiction to a Tumor-Specific Hsp90 Species

    A Hyperactive Signalosome in Acute Myeloid Leukemia Drives Addiction to a Tumor-Specific Hsp90 Species حسب Hongliang Zong, Alexander Gozman, Eloisi Caldas-Lopes, Tony Taldone, Eric M. Sturgill, Sarah Brennan, Stefan O. Ochiana, Erica M. Gomes-DaGama, Siddhartha Sen, Anna Rodina, John Koren, Michael W. Becker, Charles M. Rudin, Ari Melnick, Ross L. Levine, Gail J. Roboz, Stephen D. Nimer, Gabriela Chiosis, Mónica L. Guzmán

    منشور في 2015
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  17. 17
    HSP90-incorporating chaperome networks as biosensor for disease-related pathways in patient-specific midbrain dopamine neurons

    HSP90-incorporating chaperome networks as biosensor for disease-related pathways in patient-specific midbrain dopamine neurons حسب Sarah Kishinevsky, Tai Wang, Anna Rodina, Sun Young Chung, Chao Xu, John Philip, Tony Taldone, Suhasini Joshi, Mary L. Alpaugh, Alexander Bolaender, Simon Gutbier, Davinder Sandhu, Faranak Fattahi, Bastian Zimmer, Smit Shah, Elizabeth Chang, Carmen Inda, John Koren, Nathalie Saurat, Marcel Leist, Steven S. Gross, Venkatraman Seshan, Christine Klein, Mark Tomishima, Hediye Erdjument‐Bromage, Thomas A. Neubert, Ronald C. Henrickson, Gabriela Chiosis, Lorenz Studer

    منشور في 2018
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  18. 18
    Molecular Stressors Engender Protein Connectivity Dysfunction through Aberrant N-Glycosylation of a Chaperone

    Molecular Stressors Engender Protein Connectivity Dysfunction through Aberrant N-Glycosylation of a Chaperone حسب Pengrong Yan, Hardik J. Patel, Sahil Sharma, Adriana Corben, Tai Wang, Palak Panchal, Chenghua Yang, Weilin Sun, Thaís L.S. Araujo, Anna Rodina, Suhasini Joshi, Kenneth Robzyk, Srinivasa Gandu, Julie R. White, Elisa de Stanchina, Shanu Modi, Yelena Y. Janjigian, Elizabeth G. Hill, Bei Liu, Hediye Erdjument‐Bromage, Thomas A. Neubert, Nanette L. S. Que, Zihai Li, D.T. Gewirth, Tony Taldone, Gabriela Chiosis

    منشور في 2020
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  19. 19
    Affinity-based proteomics reveal cancer-specific networks coordinated by Hsp90

    Affinity-based proteomics reveal cancer-specific networks coordinated by Hsp90 حسب Kamalika Moulick, James H. Ahn, Hongliang Zong, Anna Rodina, Leandro Cerchietti, Erica M Gomes DaGama, Eloisi Caldas-Lopes, Kristin Beebe, Fabiana Perna, Katerina Hatzi, Ly Vu, Xinyang Zhao, Danuta Zatorska, Tony Taldone, Peter Smith‐Jones, Mary L. Alpaugh, Steven S. Gross, Nagavarakishore Pillarsetty, Thomas W. Ku, Jason S. Lewis, Steven M. Larson, Ross L. Levine, Hediye Erdjument‐Bromage, Mónica L. Guzmán, Stephen D. Nimer, Ari Melnick, Len Neckers, Gabriela Chiosis

    منشور في 2011
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  20. 20
    Systems-level analyses of protein-protein interaction network dysfunctions via epichaperomics identify cancer-specific mechanisms of stress adaptation

    Systems-level analyses of protein-protein interaction network dysfunctions via epichaperomics identify cancer-specific mechanisms of stress adaptation حسب Anna Rodina, Chao Xu, Chander Singh Digwal, Suhasini Joshi, Yogita Patel, Anand Ramaian Santhaseela, Sadık Bay, Swathi Merugu, Aftab Alam, Pengrong Yan, Chenghua Yang, Tanaya Roychowdhury, Palak Panchal, Liza Shrestha, Yanlong Kang, Sahil Sharma, Justina Almodovar, Adriana Corben, Mary L. Alpaugh, Shanu Modi, Mónica L. Guzmán, Teng Fei, Tony Taldone, Stephen D. Ginsberg, Hediye Erdjument‐Bromage, Thomas A. Neubert, Katia Manova‐Todorova, Meng-Fu Bryan Tsou, Jason C. Young, Tai Wang, Gabriela Chiosis

    منشور في 2023
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