Resultats de la cerca - Anna Radomińska‐Pandya

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  1. 1
    The crystal structure of human UDP-glucuronosyltransferase 2B7 C-terminal end is the first mammalian UGT target to be revealed: the significance for human UGTs from both the 1A and 2B families

    The crystal structure of human UDP-glucuronosyltransferase 2B7 C-terminal end is the first mammalian UGT target to be revealed: the significance for human UGTs from both the 1A and... per Anna Radomińska‐Pandya, Stacie M. Bratton, Matthew R. Redinbo, Michael J. Miley

    Publicat 2009
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  2. 2
    Distinct pharmacology and metabolism of K2 synthetic cannabinoids compared to Δ9-THC: Mechanism underlying greater toxicity?

    Distinct pharmacology and metabolism of K2 synthetic cannabinoids compared to Δ9-THC: Mechanism underlying greater toxicity? per William E. Fantegrossi, Jeffery H. Moran, Anna Radomińska‐Pandya, Paul L. Prather

    Publicat 2013
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  3. 3
    Crystal Structure of the Cofactor-Binding Domain of the Human Phase II Drug-Metabolism Enzyme UDP-Glucuronosyltransferase 2B7

    Crystal Structure of the Cofactor-Binding Domain of the Human Phase II Drug-Metabolism Enzyme UDP-Glucuronosyltransferase 2B7 per Michael J. Miley, A. Zielińska, Jeffrey E. Keenan, Stacie M. Bratton, Anna Radomińska‐Pandya, Matthew R. Redinbo

    Publicat 2007
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  4. 4
    Direct Interaction of All-trans-retinoic Acid with Protein Kinase C (PKC)

    Direct Interaction of All-trans-retinoic Acid with Protein Kinase C (PKC) per Anna Radomińska‐Pandya, Guangping Chen, Piotr J. Czernik, Joanna M. Little, Victor M. Samokyszyn, Charleata A. Carter, Grażyna Nowak

    Publicat 2000
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  5. 5
    A Major Glucuronidated Metabolite of JWH-018 Is a Neutral Antagonist at CB1 Receptors

    A Major Glucuronidated Metabolite of JWH-018 Is a Neutral Antagonist at CB1 Receptors per Kathryn A. Seely, Lisa K. Brents, Anna Radomińska‐Pandya, Gregory W. Endres, Gregory S. Keyes, Jeffery H. Moran, Paul L. Prather

    Publicat 2012
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  6. 6
    An essential role for nuclear receptors SXR/PXR in detoxification of cholestatic bile acids

    An essential role for nuclear receptors SXR/PXR in detoxification of cholestatic bile acids per Wen Xie, Anna Radomińska‐Pandya, Yanhong Shi, Cynthia M. Simon, Michael C. Nelson, Erwin S. Ong, David J. Waxman, Ronald M. Evans

    Publicat 2001
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  7. 7
    4-Hydroxyretinoic Acid, a Novel Substrate for Human Liver Microsomal UDP-glucuronosyltransferase(s) and Recombinant UGT2B7

    4-Hydroxyretinoic Acid, a Novel Substrate for Human Liver Microsomal UDP-glucuronosyltransferase(s) and Recombinant UGT2B7 per Victor M. Samokyszyn, Walter Gall, Gregory Zawada, Mary Ann Freyaldenhoven, Guangping Chen, Peter I. Mackenzie, Thomas R. Tephly, Anna Radomińska‐Pandya

    Publicat 2000
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  8. 8
    HUMAN PXR VARIANTS AND THEIR DIFFERENTIAL EFFECTS ON THE REGULATION OF HUMAN UDP-GLUCURONOSYLTRANSFERASE GENE EXPRESSION

    HUMAN PXR VARIANTS AND THEIR DIFFERENTIAL EFFECTS ON THE REGULATION OF HUMAN UDP-GLUCURONOSYLTRANSFERASE GENE EXPRESSION per Dione Gardner-Stephen, Jean‐Marie Heydel, Amit K. Goyal, Yuan Lü, Wen Xie, Tim H. Lindblom, Peter I. Mackenzie, Anna Radomińska‐Pandya

    Publicat 2004
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  9. 9
    Monohydroxylated metabolites of the K2 synthetic cannabinoid JWH-073 retain intermediate to high cannabinoid 1 receptor (CB1R) affinity and exhibit neutral antagonist to partial agonist activity

    Monohydroxylated metabolites of the K2 synthetic cannabinoid JWH-073 retain intermediate to high cannabinoid 1 receptor (CB1R) affinity and exhibit neutral antagonist to partial ag... per Lisa K. Brents, Anna Gallus‐Zawada, Anna Radomińska‐Pandya, Tamara Vasiljevik, Thomas E. Prisinzano, William E. Fantegrossi, Jeffery H. Moran, Paul L. Prather

    Publicat 2012
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  10. 10
    Control of steroid, heme, and carcinogen metabolism by nuclear pregnane X receptor and constitutive androstane receptor

    Control of steroid, heme, and carcinogen metabolism by nuclear pregnane X receptor and constitutive androstane receptor per Wen Xie, Mei-Fei Yeuh, Anna Radomińska‐Pandya, S. P. S. Saini, Yoichi Negishi, Bobbie Sue Bottroff, Geraldine Cabrera, Robert H. Tukey, Ronald M. Evans

    Publicat 2003
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  11. 11
    K2 Toxicity: Fatal Case of Psychiatric Complications Following AM2201 Exposure

    K2 Toxicity: Fatal Case of Psychiatric Complications Following AM2201 Exposure per Amy Patton, Krishna C. Chimalakonda, Cindy L. Moran, Keith R. McCain, Anna Radomińska‐Pandya, Laura P. James, Charles P. Kokes, Jeffery H. Moran

    Publicat 2013
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  12. 12
    Conjugation of Synthetic Cannabinoids JWH-018 and JWH-073, Metabolites by Human UDP-Glucuronosyltransferases

    Conjugation of Synthetic Cannabinoids JWH-018 and JWH-073, Metabolites by Human UDP-Glucuronosyltransferases per Krishna C. Chimalakonda, Stacie M. Bratton, Vi-Huyen Le, Kan Hui Yiew, Anna Dineva, Cindy L. Moran, Laura P. James, Jeffery H. Moran, Anna Radomińska‐Pandya

    Publicat 2011
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  13. 13
    Characterization of Human Hepatic and Extrahepatic UDP-Glucuronosyltransferase Enzymes Involved in the Metabolism of Classic Cannabinoids

    Characterization of Human Hepatic and Extrahepatic UDP-Glucuronosyltransferase Enzymes Involved in the Metabolism of Classic Cannabinoids per Anna Mazur, Cheryl F. Lichti, Paul L. Prather, A. Zielińska, Stacie M. Bratton, Anna Gallus‐Zawada, Moshe Finel, Grover P. Miller, Anna Radomińska‐Pandya, Jeffery H. Moran

    Publicat 2009
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  14. 14
    Natural prenylated resveratrol analogs arachidin-1 and -3 demonstrate improved glucuronidation profiles and have affinity for cannabinoid receptors

    Natural prenylated resveratrol analogs arachidin-1 and -3 demonstrate improved glucuronidation profiles and have affinity for cannabinoid receptors per Lisa K. Brents, Fabricio Medina-Bolívar, Kathryn A. Seely, Vipin A. Nair, Stacie M. Bratton, Luis Ñopo-Olazabal, Ronak Y. Patel, Haining Liu, Robert J. Doerksen, Paul L. Prather, Anna Radomińska‐Pandya

    Publicat 2011
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  15. 15
    Cytochrome P450-Mediated Oxidative Metabolism of Abused Synthetic Cannabinoids Found in K2/Spice: Identification of Novel Cannabinoid Receptor Ligands

    Cytochrome P450-Mediated Oxidative Metabolism of Abused Synthetic Cannabinoids Found in K2/Spice: Identification of Novel Cannabinoid Receptor Ligands per Krishna C. Chimalakonda, Kathryn A. Seely, Stacie M. Bratton, Lisa K. Brents, Cindy L. Moran, Gregory W. Endres, Laura P. James, Paul F. Hollenberg, Paul L. Prather, Anna Radomińska‐Pandya, Jeffery H. Moran

    Publicat 2012
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  16. 16
    Solid-Phase Extraction and Quantitative Measurement of Omega and Omega-1 Metabolites of JWH-018 and JWH-073 in Human Urine

    Solid-Phase Extraction and Quantitative Measurement of Omega and Omega-1 Metabolites of JWH-018 and JWH-073 in Human Urine per Krishna C. Chimalakonda, Cindy L. Moran, Paul D. Kennedy, Gregory W. Endres, Adam Uzieblo, Paul J. Dobrowolski, E. Kim Fifer, Jeff Lapoint, Lewis S. Nelson, Robert S. Hoffman, Laura P. James, Anna Radomińska‐Pandya, Jeffery H. Moran

    Publicat 2011
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  17. 17
    Quantitative Measurement of JWH-018 and JWH-073 Metabolites Excreted in Human Urine

    Quantitative Measurement of JWH-018 and JWH-073 Metabolites Excreted in Human Urine per Cindy L. Moran, Vi-Huyen Le, Krishna C. Chimalakonda, Amy L. Smedley, Felisia D. Lackey, Suzanne N. Owen, Paul D. Kennedy, Gregory W. Endres, Fred L. Ciske, James B. Kramer, Andrei Kornilov, L. D. Bratton, Paul J. Dobrowolski, William D. Wessinger, William E. Fantegrossi, Paul L. Prather, Laura P. James, Anna Radomińska‐Pandya, Jeffery H. Moran

    Publicat 2011
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