Výsledky vyhledávání - Anil Korkut

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  1. 1
    CellBox: Interpretable Machine Learning for Perturbation Biology with Application to the Design of Cancer Combination Therapy

    CellBox: Interpretable Machine Learning for Perturbation Biology with Application to the Design of Cancer Combination Therapy Autor Bo Yuan, Ciyue Shen, Augustin Luna, Anil Korkut, Debora S. Marks, John Ingraham, Chris Sander

    Vydáno 2020
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  2. 2
    Pan-Cancer Analysis of Mutation Hotspots in Protein Domains

    Pan-Cancer Analysis of Mutation Hotspots in Protein Domains Autor Martin L. Miller, Ed Reznik, Nicholas P. Gauthier, Bülent Arman Aksoy, Anil Korkut, Jianjiong Gao, Giovanni Ciriello, Nikolaus Schultz, Chris Sander

    Vydáno 2015
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  3. 3
    Mutant p53 protects triple-negative breast adenocarcinomas from ferroptosis in vivo

    Mutant p53 protects triple-negative breast adenocarcinomas from ferroptosis in vivo Autor Denada Dibra, Shunbin Xiong, Sydney M. Moyer, Adel K. El‐Naggar, Yuan Qi, Xiaoping Su, Elisabeth K. Kong, Anil Korkut, Guillermina Lozano

    Vydáno 2024
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  4. 4
    Drug Synergy Screen and Network Modeling in Dedifferentiated Liposarcoma Identifies CDK4 and IGF1R as Synergistic Drug Targets

    Drug Synergy Screen and Network Modeling in Dedifferentiated Liposarcoma Identifies CDK4 and IGF1R as Synergistic Drug Targets Autor Martin L. Miller, Evan Molinelli, Jayasree S. Nair, Tahir Sheikh, Rita Samy, Xiaohong Jing, Qin He, Anil Korkut, Aimeé M. Crago, Samuel Singer, Gary K. Schwartz, Chris Sander

    Vydáno 2013
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  5. 5
    Perturbation biology nominates upstream–downstream drug combinations in RAF inhibitor resistant melanoma cells

    Perturbation biology nominates upstream–downstream drug combinations in RAF inhibitor resistant melanoma cells Autor Anil Korkut, Weiqing Wang, Emek Demir, Bülent Arman Aksoy, Xiaohong Jing, Evan Molinelli, Özgün Babur, Debra L. Bemis, S. Onur Sumer, David B. Solit, Christine A. Pratilas, Chris Sander

    Vydáno 2015
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  6. 6
    Integrated Analysis of TP53 Gene and Pathway Alterations in The Cancer Genome Atlas

    Integrated Analysis of TP53 Gene and Pathway Alterations in The Cancer Genome Atlas Autor Lawrence A. Donehower, Thierry Soussi, Anil Korkut, Yuexin Liu, André Schultz, Maria Cardenas, Xubin Li, Özgün Babur, Teng‐Kuei Hsu, Olivier Lichtarge, John N. Weinstein, Rehan Akbani, David A. Wheeler

    Vydáno 2019
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  7. 7
    Integrated Analysis of TP53 Gene and Pathway Alterations in The Cancer Genome Atlas

    Integrated Analysis of TP53 Gene and Pathway Alterations in The Cancer Genome Atlas Autor Lawrence A. Donehower, Thierry Soussi, Anil Korkut, Yuexin Liu, André Schultz, Maria Cardenas, Xubin Li, Özgün Babur, Teng-Kuei Hsu, Olivier Lichtarge, John N. Weinstein, Rehan Akbani, David A. Wheeler

    Vydáno 2019
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  8. 8
    <i>KRAS</i> Allelic Variants in Biliary Tract Cancers

    <i>KRAS</i> Allelic Variants in Biliary Tract Cancers Autor Gordon Taylor Moffat, Zishuo Ian Hu, Funda Meric‐Bernstam, Elisabeth Kong, Dean Pavlick, Jeffrey S. Ross, Karthikeyan Murugesan, Lawrence N. Kwong, Anaemy Danner De Armas, Anil Korkut, Milind Javle, Jennifer J. Knox

    Vydáno 2024
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  9. 9
    The immunogenomic landscape of resected intrahepatic cholangiocarcinoma

    The immunogenomic landscape of resected intrahepatic cholangiocarcinoma Autor Fernando C. L. Carapeto, Behnaz Bozorgui, Rachna T. Shroff, Sharmeen Chagani, Luisa M. Solis Soto, Wai Chin Foo, Ignacio I. Wistuba, Funda Meric‐Bernstam, Ahmed Shalaby, Milind Javle, Anil Korkut, Lawrence N. Kwong

    Vydáno 2021
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  10. 10
    Precision Combination Therapies Based on Recurrent Oncogenic Coalterations

    Precision Combination Therapies Based on Recurrent Oncogenic Coalterations Autor Xubin Li, Elisabeth K. Dowling, Gonghong Yan, Zeynep Dereli, Behnaz Bozorgui, Parisa Imanirad, Jacob H. Elnaggar, Augustin Luna, David G. Menter, Patrick G. Pilié, Timothy A. Yap, Scott Kopetz, Chris Sander, Anil Korkut

    Vydáno 2022
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  11. 11
    Causal interactions from proteomic profiles: Molecular data meet pathway knowledge

    Causal interactions from proteomic profiles: Molecular data meet pathway knowledge Autor Özgün Babur, Augustin Luna, Anil Korkut, Funda Durupınar, Metin Can Siper, Uḡur Doḡrusöz, Alvaro Sebastian Vaca Jacome, Ryan Peckner, Karen E. Christianson, Jacob D. Jaffe, Paul T. Spellman, Joseph E. Aslan, Chris Sander, Emek Demir

    Vydáno 2021
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  12. 12
    Perturbation Biology: Inferring Signaling Networks in Cellular Systems

    Perturbation Biology: Inferring Signaling Networks in Cellular Systems Autor Evan Molinelli, Anil Korkut, Weiqing Wang, Martin L. Miller, Nicholas P. Gauthier, Xiaohong Jing, Poorvi Kaushik, Qin He, Gordon B. Mills, David B. Solit, Christine A. Pratilas, Martin Weigt, Alfredo Braunstein, Andrea Pagnani, Riccardo Zecchina, Chris Sander

    Vydáno 2013
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  13. 13
    Combining Neratinib with CDK4/6, mTOR, and MEK Inhibitors in Models of HER2-positive Cancer

    Combining Neratinib with CDK4/6, mTOR, and MEK Inhibitors in Models of HER2-positive Cancer Autor Ming Zhao, Stephen Scott, Kurt W. Evans, Erkan Yuca, Turçin Saridogan, Xiaofeng Zheng, Heping Wang, Anil Korkut, Christian X. Cruz Pico, Mehmet Demirhan, Bryce P. Kirby, Scott Kopetz, Irmina Diala, Alshad S. Lalani, Sarina A. Piha‐Paul, Funda Meric‐Bernstam

    Vydáno 2021
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  14. 14
    Co-clinical Trial of Novel Bispecific Anti-HER2 Antibody Zanidatamab in Patient-Derived Xenografts

    Co-clinical Trial of Novel Bispecific Anti-HER2 Antibody Zanidatamab in Patient-Derived Xenografts Autor Timothy P. DiPeri, Kurt W. Evans, Bailiang Wang, Ming Zhao, Argun Akçakanat, Maria Gabriela Raso, Yasmeen Q. Rizvi, Xiaofeng Zheng, Anil Korkut, Kaushik Varadarajan, Burak Uzunparmak, Ecaterina E. Dumbrava, Shubham Pant, Jaffer A. Ajani, Paula R. Pohlmann, V. Behrana Jensen, Milind Javle, Jordi Rodón, Funda Meric‐Bernstam

    Vydáno 2024
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  15. 15
    Monitoring response to neoadjuvant chemotherapy in triple negative breast cancer using circulating tumor DNA

    Monitoring response to neoadjuvant chemotherapy in triple negative breast cancer using circulating tumor DNA Autor Jennifer Chen, Sridevi Addanki, Dhruvajyoti Roy, Roland L. Bassett, Ekaterina Kalashnikova, Erik Spickard, Henry M. Kuerer, Salyna Meas, Vanessa N. Sarli, Anil Korkut, Jason B. White, Gaiane M. Rauch, Debu Tripathy, Banu K. Arun, Carlos H. Bárcenas, Clinton Yam, Himanshu Sethi, Angel Rodriguez, Minetta C. Liu, Stacy L. Moulder, Anthony Lucci

    Vydáno 2024
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  16. 16
    Large-Scale Characterization of Drug Responses of Clinically Relevant Proteins in Cancer Cell Lines

    Large-Scale Characterization of Drug Responses of Clinically Relevant Proteins in Cancer Cell Lines Autor Wei Zhao, Jun Li, Mei-Ju M. Chen, Yikai Luo, Zhenlin Ju, Nicole K. Nesser, Katie Johnson-Camacho, Christopher Boniface, Yancey Lawrence, Nupur T. Pande, Michael A. Davies, Meenhard Herlyn, Taru Muranen, Ioannis K. Zervantonakis, Erika von Euw, André Schultz, Shwetha V. Kumar, Anil Korkut, Paul T. Spellman, Rehan Akbani, Dennis J. Slamon, Joe W. Gray, Joan S. Brugge, Yiling Lu, Gordon B. Mills, Han Liang

    Vydáno 2020
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  17. 17
    The RNA-binding Protein MEX3B Mediates Resistance to Cancer Immunotherapy by Downregulating HLA-A Expression

    The RNA-binding Protein MEX3B Mediates Resistance to Cancer Immunotherapy by Downregulating HLA-A Expression Autor Lu Huang, Shruti Malu, Jodi A. McKenzie, Miles C. Andrews, Amjad H. Talukder, Trang N. Tieu, Tatiana V. Karpinets, Cara Haymaker, Marie‐Andrée Forget, Leila J. Williams, Zhe Wang, Rina M. Mbofung, Zhiqiang Wang, R. Eric Davis, Roger S. Lo, Jennifer A. Wargo, Michael A. Davies, Chantale Bernatchez, Timothy P. Heffernan, Rodabe N. Amaria, Anil Korkut, Weiyi Peng, Jason Roszik, Gregory Lizée, Scott E. Woodman, Patrick Hwu

    Vydáno 2018
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  18. 18
    Deep Learning Models Based on Pretreatment MRI and Clinicopathological Data to Predict Responses to Neoadjuvant Systemic Therapy in Triple-Negative Breast Cancer

    Deep Learning Models Based on Pretreatment MRI and Clinicopathological Data to Predict Responses to Neoadjuvant Systemic Therapy in Triple-Negative Breast Cancer Autor Zhan Xu, Zijian Zhou, Jong Bum Son, Haonan Feng, Beatriz E. Adrada, Tanya W. Moseley, Rosalind P. Candelaria, Mary S. Guirguis, Miral Patel, Gary J. Whitman, Jessica W. T. Leung, Huong Le‐Petross, Rania M. Mohamed, Bikash Panthi, Deanna L. Lane, Huiqin Chen, Peng Wei, Debu Tripathy, Jennifer K. Litton, Vicente Valero, Lei Huo, Kelly K. Hunt, Anil Korkut, Alastair M. Thompson, Wei Yang, Clinton Yam, Gaiane M. Rauch, Jingfei Ma

    Vydáno 2025
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  19. 19
    A Pan-Cancer Analysis Reveals High-Frequency Genetic Alterations in Mediators of Signaling by the TGF-β Superfamily

    A Pan-Cancer Analysis Reveals High-Frequency Genetic Alterations in Mediators of Signaling by the TGF-β Superfamily Autor Anil Korkut, Sobia Zaidi, Rupa S. Kanchi, Shuyun Rao, Nancy R. Gough, André Schultz, Xubin Li, Philip L. Lorenzi, Ashton C. Berger, Gordon Robertson, Lawrence N. Kwong, Mike Datto, Jason Roszik, Shiyun Ling, Visweswaran Ravikumar, Ganiraju C. Manyam, Arvind Rao, Simon Shelley, Yuexin Liu, Zhenlin Ju, Donna E. Hansel, Guillermo de Velasco, Arjun Pennathur, Jesper B. Andersen, Colm J. O’Rourke, Kazufumi Ohshiro, Wilma Jogunoori, Bao‐Ngoc Nguyen, Shulin Li, Hatice U. Osmanbeyoglu, Jaffer A. Ajani, Sendurai A. Mani, Andres Houseman, Maciej Wiznerowicz, Jian Chen, Shoujun Gu, Wencai Ma, Jiexin Zhang, Pan Tong, Andrew D. Cherniack, Chu‐Xia Deng, Linda Resar, John N. Weinstein, Lopa Mishra, Rehan Akbani, Rory Johnson, John A. Demchok, Ina Felau, Melpomeni Kasapi, Martin L. Ferguson, Carolyn M. Hutter, Heidi J. Sofia, Roy Tarnuzzer, Linghua Wang, Liming Yang, Jean C. Zenklusen, Jiashan Zhang, Sudha Chudamani, Jia Liu, Laxmi Lolla, Rashi Naresh, Todd Pihl, Qiang Sun, Yunhu Wan, Ye Wu, Juok Cho, Timothy Defreitas, Scott Frazer, Nils Gehlenborg, Gad Getz, David I. Heiman, Seungchan Kim, Michael S. Lawrence, Pei Lin, Thomas J. Giordano, Michael S. Noble, Gordon Saksena, Doug Voet, Hailei Zhang, Brady Bernard, Nyasha Chambwe, Varsha Dhankani, Theo Knijnenburg, Roger Kramer, Kalle Leinonen, Yuexin Liu, Michael B. Miller, Sheila M. Reynolds, Ilya Shmulevich, Vésteinn Thórsson, Wei Zhang, Rehan Akbani, Bradley M. Broom, Apurva M. Hegde, Zhenlin Ju, Rupa S. Kanchi, Anil Korkut, Jun Li, Han Liang, Shiyun Ling

    Vydáno 2018
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  20. 20
    A Comprehensive Pan-Cancer Molecular Study of Gynecologic and Breast Cancers

    A Comprehensive Pan-Cancer Molecular Study of Gynecologic and Breast Cancers Autor Ashton C. Berger, Anil Korkut, Rupa S. Kanchi, Apurva M. Hegde, Walter F. Lenoir, Wenbin Liu, Yuexin Liu, Huihui Fan, Hui Shen, Visweswaran Ravikumar, Arvind Rao, André Schultz, Xubin Li, Pavel Sumazin, Cecilia Williams, Pieter Mestdagh, Preethi H. Gunaratne, Christina Yau, Reanne Bowlby, A. Gordon Robertson, Daniel Guimarães Tiezzi, Chen Wang, Andrew D. Cherniack, Andrew K. Godwin, Nicole M. Kuderer, Janet S. Rader, Rosemary E. Zuna, Anil K. Sood, Alexander J. Lazar, Akinyemi I. Ojesina, Clement Adebamowo, Sally N. Adebamowo, Keith Baggerly, Ting-Wen Chen, Hua‐Sheng Chiu, Steve Lefever, Liang Liu, Karen L. MacKenzie, Sandra Oršulić, Jason Roszik, Carl Simon Shelley, Qianqian Song, Christopher P. Vellano, Nicolas Wentzensen, John N. Weinstein, Gordon B. Mills, Douglas A. Levine, Rehan Akbani, Rory Johnson, John A. Demchok, Ina Felau, Melpomeni Kasapi, Martin L. Ferguson, Carolyn M. Hutter, Heidi J. Sofia, Roy Tarnuzzer, Zhining Wang, Liming Yang, Jean C. Zenklusen, Jiashan Zhang, Sudha Chudamani, Jia Liu, Laxmi Lolla, Rashi Naresh, Todd Pihl, Qiang Sun, Yunhu Wan, Ye Wu, Juok Cho, Timothy Defreitas, Scott Frazer, Nils Gehlenborg, Gad Getz, David I. Heiman, Seungchan Kim, Michael S. Lawrence, Pei Lin, Thomas J. Giordano, Michael S. Noble, Gordon Saksena, Doug Voet, Hailei Zhang, Brady Bernard, Nyasha Chambwe, Varsha Dhankani, Theo Knijnenburg, Roger Kramer, Kalle Leinonen, Yuexin Liu, Michael Miller, Sheila M. Reynolds, Ilya Shmulevich, Vésteinn Thórsson, Wei Zhang, Rehan Akbani, Bradley M. Broom, Apurva M. Hegde, Zhenlin Ju, Rupa S. Kanchi, Anil Korkut

    Vydáno 2018
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