检索结果 - Angus, Steven P

A role for Mediator complex subunit MED13L in Rb/E2F-induced growth arrest 由 Angus, Steven P., Nevins, Joseph R.

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Engineering a Protein Binder Specific for p38α with Interface Expansion 由 Hussain, Mahmud, Angus, Steven P., Kuhlman, Brian

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MAP3K1: Genomic Alterations in Cancer and Function in Promoting Cell Survival or Apoptosis 由 Pham, Trang T., Angus, Steven P., Johnson, Gary L.

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Retinoblastoma Tumor Suppressor: Analyses of Dynamic Behavior in Living Cells Reveal Multiple Modes of Regulation 由 Angus, Steven P., Solomon, David A., Kuschel, Lioba, Hennigan, Robert F., Knudsen, Erik S.

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Interaction of E2F7 Transcription Factor with E2F1 and C-terminal-binding Protein (CtBP) Provides a Mechanism for E2F7-dependent Transcription Repression 由 Liu, Beiyu, Shats, Igor, Angus, Steven P., Gatza, Michael L., Nevins, Joseph R.

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Molecular Pathways: Adaptive Kinome Reprogramming in Response to Targeted Inhibition of the BRAF-MEK-ERK Pathway in Cancer 由 Johnson, Gary L., Stuhlmiller, Timothy J., Angus, Steven P., Zawistowski, Jon S., Graves, Lee M.

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FOXO Transcription Factors Control E2F1 Transcriptional Specificity and Apoptotic Function 由 Shats, Igor, Gatza, Michael L., Liu, Beiyu, Angus, Steven P., You, Lingchong, Nevins, Joseph R.

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Retinoblastoma Tumor Suppressor Protein Signals through Inhibition of Cyclin-Dependent Kinase 2 Activity To Disrupt PCNA Function in S Phase 由 Sever-Chroneos, Zvjezdana, Angus, Steven P., Fribourg, Anne F., Wan, Huajing, Todorov, Ivan, Knudsen, Karen E., Knudsen, Erik S.

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RB Reversibly Inhibits DNA Replication via Two Temporally Distinct Mechanisms 由 Angus, Steven P., Mayhew, Christopher N., Solomon, David A., Braden, Wesley A., Markey, Michael P., Okuno, Yukiko, Cardoso, M. Cristina, Gilbert, David M., Knudsen, Erik S.

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SOX4 and SMARCA4 cooperatively regulate PI3k signaling through transcriptional activation of TGFBR2 由 Mehta, Gaurav A., Angus, Steven P., Khella, Christen A., Tong, Kevin, Khanna, Pooja, Dixon, Shelley A. H., Verzi, Michael P., Johnson, Gary L., Gatza, Michael L.

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Nf1 mutant tumors undergo transcriptome and kinome re-modeling after inhibition of either mTOR or MEK 由 Pucciarelli, Daniela, Angus, Steven P., Huang, Benjamin, Zhang, Chi, Nakaoka, Hiroki J., Krishnamurthi, Ganesh, Bandyopadhyay, Sourav, Clapp, D. Wade, Shannon, Kevin, Johnson, Gary L., Nakamura, Jean L.

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Kinome and Transcriptome Profiling Reveal Broad and Distinct Activities of Erlotinib, Sunitinib, and Sorafenib in the Mouse Heart and Suggest Cardiotoxicity From Combined Signal Tr... 由 Stuhlmiller, Timothy J., Zawistowski, Jon S., Chen, Xin, Sciaky, Noah, Angus, Steven P., Hicks, Sean T., Parry, Traci L., Huang, Wei, Beak, Ju Youn, Willis, Monte S., Johnson, Gary L., Jensen, Brian C.

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New mechanisms of resistance to MEK inhibitors in melanoma revealed by intravital imaging 由 Brighton, Hailey E., Angus, Steven P., Bo, Tao, Roques, Jose, Tagliatela, Alicia C., Darr, David B., Karagoz, Kubra, Sciaky, Noah, Gatza, Michael L., Sharpless, Norman E., Johnson, Gary L., Bear, James E.

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A molecular basis for neurofibroma-associated skeletal manifestations in NF1 由 Ma, Yun, Gross, Andrea, Dombi, Eva, Pemov, Alex, Choi, Kwangmin, Chaney, Katherine, Rhodes, Steven D., Angus, Steven P, Sciaky, Noah, Clapp, D Wade, Ratner, Nancy, Widemann, Brigitte C, Rios, Jonathan J, Elefteriou, Florent

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Inhibition of Aurora A Kinase in Combination with Chemotherapy Induces Synthetic Lethality and Overcomes Chemoresistance in Myc-overexpressing Lymphoma 由 Park, Steven I., Lin, Carolina P., Ren, Natalie, Angus, Steven P., Dittmer, Dirk P., Foote, Michael, Parton, Trevor, Bhatt, Aadra P., Fedoriw, Yuri D., Roth, Daniel P., Cann, Marissa L., Johnson, Gary L., Damania, Blossom

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GSK2801, a BAZ2/BRD9 bromodomain inhibitor, synergizes with BET inhibitors to induce apoptosis in triple-negative breast cancer. 由 Bevill, Samantha M., Olivares-Quintero, Jose F., Sciaky, Noah, Golitz, Brian T., Singh, Darshan, Beltran, Adriana S., Rashid, Naim U., Stuhlmiller, Timothy J., Hale, Andrew, Moorman, Nathaniel J., Santos, Charlene M., Angus, Steven P., Zawistowski, Jon S., Johnson, Gary L.

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Proteomic analysis defines kinase taxonomies specific for subtypes of breast cancer 由 Collins, Kyla A.L., Stuhlmiller, Timothy J., Zawistowski, Jon S., East, Michael P., Pham, Trang T., Hall, Claire R., Goulet, Daniel R., Bevill, Samantha M., Angus, Steven P., Velarde, Sara H., Sciaky, Noah, Oprea, Tudor I., Graves, Lee M., Johnson, Gary L., Gomez, Shawn M.

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EPH receptor signaling as a novel therapeutic target in NF2-deficient meningioma 由 Angus, Steven P, Oblinger, Janet L, Stuhlmiller, Timothy J, DeSouza, Patrick A, Beauchamp, Roberta L, Witt, Luke, Chen, Xin, Jordan, Justin T, Gilbert, Thomas S K, Stemmer-Rachamimov, Anat, Gusella, James F, Plotkin, Scott R, Haggarty, Stephen J, Chang, Long-Sheng, Johnson, Gary L, Ramesh, Vijaya

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Inhibition of Lapatinib-induced Kinome Reprogramming in ERBB2-positive Breast Cancer by Targeting BET Family Bromodomains 由 Stuhlmiller, Timothy J., Miller, Samantha M., Zawistowski, Jon S., Nakamura, Kazuhiro, Beltran, Adriana S., Duncan, James S., Angus, Steven P., Collins, Kyla A. L., Granger, Deborah A., Reuther, Rachel A., Graves, Lee M., Gomez, Shawn M., Kuan, Pei-Fen, Parker, Joel S., Chen, Xin, Sciaky, Noah, Carey, Lisa A., Earp, H. Shelton, Jin, Jian, Johnson, Gary L.

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High-content image-based analysis and proteomic profiling identifies Tau phosphorylation inhibitors in a human iPSC-derived glutamatergic neuronal model of tauopathy 由 Cheng, Chialin, Reis, Surya A., Adams, Emily T., Fass, Daniel M., Angus, Steven P., Stuhlmiller, Timothy J., Richardson, Jared, Olafson, Hailey, Wang, Eric T., Patnaik, Debasis, Beauchamp, Roberta L., Feldman, Danielle A., Silva, M. Catarina, Sur, Mriganka, Johnson, Gary L., Ramesh, Vijaya, Miller, Bruce L., Temple, Sally, Kosik, Kenneth S., Dickerson, Bradford C., Haggarty, Stephen J.

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