Search Results - Andrew D. Bretherick

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  1. 1
    The genomic basis of human lifespan

    The genomic basis of human lifespan by Paul R. H. J. Timmers, Ninon Mounier, Kristi Läll, Krista Fischer, Ning Zhang, Xiao Feng, Andrew D. Bretherick, David W. Clark, Xia Shen, Tõnu Esko, Zoltán Kutalik, James F. Wilson, Peter K. Joshi

    Published 2018
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  2. 2
    Identification of epigenome-wide DNA methylation differences between carriers of APOE ε4 and APOE ε2 alleles

    Identification of epigenome-wide DNA methylation differences between carriers of APOE ε4 and APOE ε2 alleles by Rosie M. Walker, Kadi Vaher, Mairead L. Bermingham, Stewart W. Morris, Andrew D. Bretherick, Yanni Zeng, Konrad Rawlik, Carmen Amador, Archie Campbell, Chris Haley, Caroline Hayward, David J. Porteous, Andrew M. McIntosh, Riccardo E. Marioni, Kathryn L. Evans

    Published 2021
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  3. 3
    Linking protein to phenotype with Mendelian Randomization detects 38 proteins with causal roles in human diseases and traits

    Linking protein to phenotype with Mendelian Randomization detects 38 proteins with causal roles in human diseases and traits by Andrew D. Bretherick, Oriol Canela‐Xandri, Peter K. Joshi, David W. Clark, Konrad Rawlik, Thibaud Boutin, Yanni Zeng, Carmen Amador, Pau Navarro, Igor Rudan, Alan F. Wright, Harry Campbell, Véronique Vitart, Caroline Hayward, James F. Wilson, Albert Tenesa, Chris P. Ponting, J. Kenneth Baillie, Chris Haley

    Published 2020
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  4. 4
    Parent of origin genetic effects on methylation in humans are common and influence complex trait variation

    Parent of origin genetic effects on methylation in humans are common and influence complex trait variation by Yanni Zeng, Carmen Amador, Charley Xia, Riccardo E. Marioni, Duncan Sproul, Rosie M. Walker, Stewart W. Morris, Andrew D. Bretherick, Oriol Canela‐Xandri, Thibaud Boutin, David W. Clark, Archie Campbell, Konrad Rawlik, Caroline Hayward, Réka Nagy, Albert Tenesa, David J. Porteous, James F. Wilson, Ian J. Deary, Kathryn L. Evans, Andrew M. McIntosh, Pau Navarro, Chris Haley

    Published 2019
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  5. 5
    Genome‐Wide Association Study of NAFLD Using Electronic Health Records

    Genome‐Wide Association Study of NAFLD Using Electronic Health Records by Cameron J. Fairfield, Thomas M Drake, Riinu Pius, Andrew D. Bretherick, Archie Campbell, David W. Clark, Jonathan A. Fallowfield, Caroline Hayward, Neil C. Henderson, Peter K. Joshi, Nicholas L. Mills, David J. Porteous, Prakash Ramachandran, Robert K. Semple, Catherine A. Shaw, Cathie Sudlow, Paul R. H. J. Timmers, James F. Wilson, Stephen J. Wigmore, Ewen M. Harrison, Athina Spiliopoulou

    Published 2021
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  6. 6
    Genetic mechanisms of critical illness in Covid-19

    Genetic mechanisms of critical illness in Covid-19 by Erola Pairo‐Castineira, Sara Clohisey, Lucija Klarić, Andrew D. Bretherick, Konrad Rawlik, Nick Parkinson, Dorota Pasko, Susan Walker, Anne Richmond, Max Head Fourman, Clark D Russell, Andrew Law, James Furniss, Viktoria‐Eleni Gountouna, Nicola Wrobel, Loukas Moutsianas, Bo Wang, Alison Meynert, Zhijian Yang, Ranran Zhai, Chenqing Zheng, Fiona Griffiths, Wilna Oosthuyzen, Graeme R. Grimes, Barbara Shih, Seán Keating, Marie Zechner, Chris Haley, David J. Porteous, Caroline Hayward, Julian C. Knight, Charlotte Summers, Manu Shankar‐Hari, Paul Klenerman, Lance Turtle, Antonia Ho, Charles Hinds, Peter Horby, Alistair Nichol, David M. Maslove, Lowell Ling, Daniel F. McAuley, Hugh Montgomery, Timothy Walsh, Xia Shen, Kathy Rowan, Angie Fawkes, Lee Murphy, Chris P. Ponting, Albert Tenesa, Mark J. Caulfield, Richard H. Scott, Peter Openshaw, Malcolm G. Semple, Véronique Vitart, James F. Wilson, J. Kenneth Baillie

    Published 2020
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  7. 7
    Genetic mechanisms of critical illness in COVID-19

    Genetic mechanisms of critical illness in COVID-19 by Erola Pairo‐Castineira, Sara Clohisey, Lucija Klarić, Andrew D. Bretherick, Konrad Rawlik, Dorota Pasko, Susan Walker, Nick Parkinson, Max Head Fourman, Clark D Russell, James Furniss, Anne Richmond, Viktoria‐Eleni Gountouna, Nicola Wrobel, David A Harrison, Bo Wang, Yang Wu, Alison Meynert, Fiona Griffiths, Wilna Oosthuyzen, Athanasios Kousathanas, Loukas Moutsianas, Zhijian Yang, Ranran Zhai, Chenqing Zheng, Graeme R. Grimes, Rupert Beale, Jonathan Millar, Barbara Shih, Seán Keating, Marie Zechner, Chris Haley, David J. Porteous, Caroline Hayward, Jian Yang, Julian C. Knight, Charlotte Summers, Manu Shankar‐Hari, Paul Klenerman, Lance Turtle, Antonia Ho, Shona C. Moore, Charles Hinds, Peter Horby, Alistair Nichol, David M. Maslove, Lowell Ling, Danny McAuley, Hugh Montgomery, Timothy Walsh, Alexandre C. Pereira, Alessandra Renieri, Xia Shen, Chris P. Ponting, Angie Fawkes, Albert Tenesa, Mark J. Caulfield, Richard H. Scott, Kathy Rowan, Lee Murphy, Peter Openshaw, Malcolm G. Semple, Andrew Law, Véronique Vitart, James F. Wilson, J. Kenneth Baillie

    Published 2020
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  8. 8
    Genetic Landscape of the ACE2 Coronavirus Receptor

    Genetic Landscape of the ACE2 Coronavirus Receptor by Zhijian Yang, Erin Macdonald-Dunlop, Jiantao Chen, Ranran Zhai, Ting Li, Anne Richmond, Lucija Klarić, Nicola Pirastu, Ning Zheng, Chenqing Zheng, Yipeng Wang, Tingting Huang, Yazhou He, Huiming Guo, Kejun Ying, Stefan Gustafsson, Bram P. Prins, Anna Ramisch, Emmanouil T. Dermitzakis, Grace Png, Niclas Eriksson, Jeffrey Haessler, Xiaowei Hu, Daniela Zanetti, Thibaud Boutin, Shih‐Jen Hwang, Eleanor Wheeler, Maik Pietzner, Laura M. Raffield, Anette Kalnapenkis, James E. Peters, Ana Viñuela, Arthur Gilly, Sölve Elmståhl, George Dedoussis, John R. Petrie, Ozren Polašek, Lasse Folkersen, Yan Chen, Chen Yao, Urmo Võsa, Erola Pairo‐Castineira, Sara Clohisey, Andrew D. Bretherick, Konrad Rawlik, Tõnu Esko, Stefan Enroth, Åsa Johansson, Ulf Gyllensten, Claudia Langenberg, Daniel Levy, Caroline Hayward, Themistocles L. Assimes, Charles Kooperberg, Ani Manichaikul, Agneta Siegbahn, Lars Wallentin, Lars Lind, Eleftheria Zeggini, Jochen M. Schwenk, Adam S. Butterworth, Karl Michaëlsson, Yudi Pawitan, Peter K. Joshi, J. Kenneth Baillie, Anders Mälarstig, Alexander P. Reiner, James F. Wilson, Xia Shen

    Published 2022
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  9. 9
    Author response: Genomics of 1 million parent lifespans implicates novel pathways and common diseases and distinguishes survival chances

    Author response: Genomics of 1 million parent lifespans implicates novel pathways and common diseases and distinguishes survival chances by Paul R. H. J. Timmers, Ninon Mounier, Kristi Läll, Krista Fischer, Ning Zheng, Xiao Feng, Andrew D. Bretherick, David W. Clark, Mawussé Agbessi, Habibul Ahsan, Isabel Alves, Anand Kumar Andiappan, Philip Awadalla, Alexis Battle, Marc Jan Bonder, Dorret I. Boomsma, Mark Christiansen, Annique Claringbould, Patrick Deelen, Jenny van Dongen, Tõnu Esko, Marie‐Julie Favé, Lude Franke, T Frayling, Sina A. Gharib, Greg Gibson, Gibran Hemani, Rick Jansen, A Kalnapenkis, Silva Kasela, Jarno L. T. Kettunen, Y Kim, Holger Kirsten, Péter Kovács, Knut Krohn, Jaanika Kronberg-Guzman, Viktorija Kukushkina, Zoltán Kutalik, Mika Kähönen, B Lee, Terho Lehtimäki, Markus Loeffler, Urko M. Marigorta, Andres Metspalu, Joyce B. J. van Meurs, Lili Milani, Martina Müller‐Nurasyid, Matthias Nauck, Michel G. Nivard, Brenda W.J.H. Penninx, Markus Perola, Natalia Pervjakova, Brandon L. Pierce, Joseph E. Powell, Holger Prokisch, BM Psaty, Olli T. Raitakari, Susan M. Ring, Samuli Ripatti, Olaf Rötzschke, Sina Rüeger, A Saha, Markus Scholz, Katharina Schramm, Ilkka Seppälä, Michael Stümvoll, Patrick Sullivan, Alexander Teumer, Joachim Thiery, Tong Lin, Anke Tönjes, Joost Verlouw, Peter M. Visscher, Urmo Võsa, Uwe Völker, Hanieh Yaghootkar, Jian Yang, Biao Zeng, F Zhang, Xia Shen, Tõnu Esko, Zoltán Kutalik, James F. Wilson, Peter K. Joshi

    Published 2018
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  10. 10
    Genomic evaluation of circulating proteins for drug target characterisation and precision medicine

    Genomic evaluation of circulating proteins for drug target characterisation and precision medicine by Lasse Folkersen, Stefan Gustafsson, Qin Wang, Daniel Hvidberg Hansen, Åsa K. Hedman, Andrew J. Schork, Karen Page, Daria V. Zhernakova, Yang Wu, James E. Peters, Niclas Ericsson, Sarah E. Bergen, Thibaud Boutin, Andrew D. Bretherick, Stefan Enroth, A Kalnapenkis, Jesper R. Gådin, Bianca E Suur, Yan Chen, Ljubica Matic, Jeremy D. Gale, Julie Lee, Weidong Zhang, Amira Quazi, Mika Ala‐Korpela, Seung Hoan Choi, Annique Claringbould, John Danesh, George Davey Smith, Federico De Masi, Sölve Elmståhl, Gunnar Engström, Eric B. Fauman, Céline Fernandez, Lude Franke, Paul W. Franks, Vilmantas Giedraitis, Chris Haley, Anders Hamsten, Andrés Ingason, Åsa Johansson, Peter K. Joshi, Lars Lind, Cecilia M. Lindgren, Steven A. Lubitz, Tom Palmer, Erin Macdonald-Dunlop, Martin Magnusson, Olle Melander, Karl Michaëlsson, Andrew P. Morris, Reedik Mägi, Michael W. Nagle, Peter M. Nilsson, Jan Nilsson, Marju Orho‐Melander, Ozren Polašek, Bram P. Prins, Erik Pålsson, Ting Qi, Marketa Sjögren, Johan Sundström, Praveen Surendran, Urmo Võsa, Thomas Werge, Rasmus Wernersson, Harm-Jan Westra, Jian Yang, Alexandra Zhernakova, Johan Ärnlöv, Jingyuan Fu, Gustav Smith, Tõnu Esko, Caroline Hayward, Ulf Gyllensten, Mikael Landén, Agneta Siegbahn, Jim Wilson, Lars Wallentin, Adam S. Butterworth, Michael V. Holmes, Erik Ingelsson, Anders Mälarstig

    Published 2020
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  11. 11
    Genomic and drug target evaluation of 90 cardiovascular proteins in 30,931 individuals

    Genomic and drug target evaluation of 90 cardiovascular proteins in 30,931 individuals by Lasse Folkersen, Stefan Gustafsson, Qin Wang, Daniel Hvidberg Hansen, Åsa K. Hedman, Andrew J. Schork, Karen Page, Daria V. Zhernakova, Yang Wu, James E. Peters, Niclas Eriksson, Sarah E. Bergen, Thibaud Boutin, Andrew D. Bretherick, Stefan Enroth, Anette Kalnapenkis, Jesper R. Gådin, Bianca E Suur, Yan Chen, Ljubica Matic, Jeremy D. Gale, Julie Lee, Weidong Zhang, Amira Quazi, Mika Ala‐Korpela, Seung Hoan Choi, Annique Claringbould, John Danesh, George Davey Smith, Federico De Masi, Sölve Elmståhl, Gunnar Engström, Eric B. Fauman, Céline Fernandez, Lude Franke, Paul W. Franks, Vilmantas Giedraitis, Chris Haley, Anders Hamsten, Andrés Ingason, Åsa Johansson, Peter K. Joshi, Lars Lind, Cecilia M. Lindgren, Steven A. Lubitz, Tom Palmer, Erin Macdonald-Dunlop, Martin Magnusson, Olle Melander, Karl Michaëlsson, Andrew P. Morris, Reedik Mägi, Michael W. Nagle, Peter M. Nilsson, Jan Nilsson, Marju Orho‐Melander, Ozren Polašek, Bram P. Prins, Erik Pålsson, Ting Qi, Marketa Sjögren, Johan Sundström, Praveen Surendran, Urmo Võsa, Thomas Werge, Rasmus Wernersson, Harm-Jan Westra, Jian Yang, Alexandra Zhernakova, Johan Ärnlöv, Jingyuan Fu, J. G. Smith, Tõnu Esko, Caroline Hayward, Ulf Gyllensten, Mikael Landén, Agneta Siegbahn, James F. Wilson, Lars Wallentin, Adam S. Butterworth, Michael V. Holmes, Erik Ingelsson, Anders Mälarstig

    Published 2020
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  12. 12
    Genomics of 1 million parent lifespans implicates novel pathways and common diseases and distinguishes survival chances

    Genomics of 1 million parent lifespans implicates novel pathways and common diseases and distinguishes survival chances by Paul R. H. J. Timmers, Ninon Mounier, Kristi Läll, Krista Fischer, Ning Zheng, Xiao Feng, Andrew D. Bretherick, David W. Clark, Mawussé Agbessi, Habibul Ahsan, Isabel Alves, Anand Kumar Andiappan, Philip Awadalla, Alexis Battle, Marc Jan Bonder, Dorret I. Boomsma, Mark Christiansen, Annique Claringbould, Patrick Deelen, Jenny van Dongen, Tõnu Esko, Marie‐Julie Favé, Lude Franke, T Frayling, Sina A. Gharib, Greg Gibson, Gibran Hemani, Rick Jansen, A Kalnapenkis, Silva Kasela, Jarno L. T. Kettunen, Y Kim, Holger Kirsten, Péter Kovács, Knut Krohn, Jaanika Kronberg-Guzman, Viktorija Kukushkina, Zoltán Kutalik, Mika Kähönen, B Lee, Terho Lehtimäki, Markus Loeffler, Urko M. Marigorta, Andres Metspalu, Joyce B. J. van Meurs, Lili Milani, Martina Müller‐Nurasyid, Matthias Nauck, Michel G. Nivard, Brenda W.J.H. Penninx, Markus Perola, Natalia Pervjakova, Brandon L. Pierce, Joseph E. Powell, Holger Prokisch, BM Psaty, Olli Raitakari, Susan M. Ring, Samuli Ripatti, Olaf Rötzschke, Sina Rüeger, A Saha, Markus Scholz, Katharina Schramm, Ilkka Seppälä, Michael Stümvoll, Patrick F. Sullivan, Alexander Teumer, Joachim Thiery, Tong Lin, Anke Tönjes, Joost Verlouw, Peter M. Visscher, Urmo Võsa, Uwe Völker, Hanieh Yaghootkar, Jian Yang, Biao Zeng, F Zhang, Mawussé Agbessi, Habibul Ahsan, Isabel Alves, Anand Kumar Andiappan, Philip Awadalla, Alexis Battle, Marc Jan Bonder, Dorret I. Boomsma, Mark Christiansen, Annique Claringbould, Patrick Deelen, Jenny van Dongen, Tõnu Esko, Marie‐Julie Favé, Lude Franke, T Frayling, Sina A. Gharib, Greg Gibson, Gibran Hemani, Rick Jansen, A Kalnapenkis

    Published 2019
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  13. 13
    GWAS and meta-analysis identifies 49 genetic variants underlying critical COVID-19

    GWAS and meta-analysis identifies 49 genetic variants underlying critical COVID-19 by Erola Pairo‐Castineira, Konrad Rawlik, Andrew D. Bretherick, Ting Qi, Yang Wu, Isar Nassiri, Glenn A. McConkey, Marie Zechner, Lucija Klarić, Fiona Griffiths, Wilna Oosthuyzen, Athanasios Kousathanas, Anne Richmond, Jonathan Millar, Clark D Russell, Tomas Malinauskas, Ryan S. Thwaites, Kirstie Morrice, Seán Keating, David M. Maslove, Alistair Nichol, Malcolm G. Semple, Julian C. Knight, Manu Shankar‐Hari, Charlotte Summers, Charles Hinds, Peter Horby, Lowell Ling, Daniel F. McAuley, Hugh Montgomery, Peter Openshaw, Colin B. Begg, Timothy Walsh, Albert Tenesa, Carlos Flores, José A. Riancho, Augusto Rojas‐Martínez, Pablo Lapunzina, Sara Clohisey, Johnny Millar, Manu Shankar‐Hari, Emma Aitkin, Latha Aravindan, Ruth Armstrong, J. Kenneth Baillie, Heather Biggs, Ceilia Boz, Adam Brown, Primmy Chikowore, Richard Clark, Audrey Coutts, J. Terrence Coyle, Louise Cullum, Sukamal Das, Nicky Day, Lorna Donnelly, Esther Duncan, Paul Finernan, Max Head Fourman, Anita Furlong, James Furniss, Bernadette Gallagher, Tammy Gilchrist, Ailsa Golightly, Fiona Griffiths, Katarzyna Hafezi, Debbie Hamilton, Ross Hendry, Naomi Kearns, Dawn Law, R. M. Law, Sarah Law, Rebecca Lidstone-Scott, Christen Lauder, Louise MacGillivray, Alan Maclean, Hanning Mal, Sarah McCafferty, Ellie Mcmaster, Jen Meikle, Shona C. Moore, Sheena Murphy, Hellen Mybaya, Miranda Odam, Wilna Oosthuyzen, Chenqing Zheng, Jiantao Chen, Nick Parkinson, Trevor Paterson, Petra Tucker, Katherine Schon, Andrew Stenhouse, Mihaela Das, Maaike Swets, Helen Szoor-McElhinney, Filip Taneski, Lance Turtle, Tony Wackett, Mairi Ward, Jane Weaver

    Published 2023
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  14. 14
    Genomic and phenotypic insights from an atlas of genetic effects on DNA methylation

    Genomic and phenotypic insights from an atlas of genetic effects on DNA methylation by Josine L. Min, Gibran Hemani, Eilís Hannon, Koen F. Dekkers, Juan Castillo‐Fernandez, René Luijk, Elena Carnero‐Montoro, Daniel J. Lawson, Kimberley Burrows, Matthew Suderman, Andrew D. Bretherick, Tom G. Richardson, Johanna Klughammer, Valentina Iotchkova, Gemma C. Sharp, Ahmad Al Khleifat, Aleksey Shatunov, Alfredo Iacoangeli, Wendy L. McArdle, Karen Ho, Ashish Kumar, Cilla Söderhäll, Carolina Soriano‐Tárraga, Eva Giralt‐Steinhauer, Nabila Kazmi, Dan Mason, Allan F. McRae, David L. Corcoran, Karen Sugden, Silva Kasela, Alexia Cardona, Felix R. Day, Giovanni Cugliari, Clara Viberti, Simonetta Guarrera, Michael C. Lerro, Richa Gupta, Sailalitha Bollepalli, Pooja R. Mandaviya, Yanni Zeng, Toni‐Kim Clarke, Rosie M. Walker, Vanessa Schmoll, Darina Czamara, Carlos Ruiz-Arenas, Faisal I. Rezwan, Riccardo E. Marioni, Tian Lin, Yvonne Awaloff, Marine Germain, Dylan Aïssi, Ramona Zwamborn, Kristel van Eijk, Annelot M. Dekker, Jenny van Dongen, Jouke‐Jan Hottenga, Gonneke Willemsen, Cheng‐Jian Xu, Guillermo Barturen, Francesc Català‐Moll, Martin Kerick, Carol A. Wang, Phillip E. Melton, Hannah R. Elliott, Jean Shin, Manon Bernard, İdil Yet, Melissa Smart, T.J. Gorrie-Stone, Chris Shaw, Ammar Al‐Chalabi, Susan M. Ring, Göran Pershagen, Erik Melén, Jordi Jiménez‐Conde, Jaume Roquer, Debbie A. Lawlor, John Wright, Nicholas G. Martin, Grant W. Montgomery, Terrie E. Moffitt, Richie Poulton, Tõnu Esko, Lili Milani, Andres Metspalu, John R. B. Perry, Ken K. Ong, Nicholas J. Wareham, Giuseppe Matullo, Carlotta Sacerdote, Salvatore Panico, Avshalom Caspi, Louise Arseneault, France Gagnon, Miina Ollikainen, Jaakko Kaprio, Janine F. Felix, Fernando Rivadeneira, Henning Tiemeier, Marinus H. van IJzendoorn

    Published 2021
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