Search Results - Andrea N. Edginton

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  1. 1
    Physiologically Based Pharmacokinetic Modeling and Simulation in Pediatric Drug Development

    Physiologically Based Pharmacokinetic Modeling and Simulation in Pediatric Drug Development by A. R. Maharaj, Andrea N. Edginton

    Published 2014
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  2. 2
    Examining Small Intestinal Transit Time as a Function of Age: Is There Evidence to Support Age-Dependent Differences among Children?

    Examining Small Intestinal Transit Time as a Function of Age: Is There Evidence to Support Age-Dependent Differences among Children? by A. R. Maharaj, Andrea N. Edginton

    Published 2016
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  3. 3
    Physiologically‐Based Pharmacokinetic Modeling vs. Allometric Scaling for the Prediction of Infliximab Pharmacokinetics in Pediatric Patients

    Physiologically‐Based Pharmacokinetic Modeling vs. Allometric Scaling for the Prediction of Infliximab Pharmacokinetics in Pediatric Patients by Paul R. V. Malik, Andrea N. Edginton

    Published 2019
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  4. 4
    A Workflow Example of PBPK Modeling to Support Pediatric Research and Development: Case Study with Lorazepam

    A Workflow Example of PBPK Modeling to Support Pediatric Research and Development: Case Study with Lorazepam by A. R. Maharaj, Jeffrey S. Barrett, Andrea N. Edginton

    Published 2013
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  5. 5
    Data Analysis Protocol for the Development and Evaluation of Population Pharmacokinetic Models for Incorporation Into the Web-Accessible Population Pharmacokinetic Service - Hemophilia (WAPPS-Hemo)

    Data Analysis Protocol for the Development and Evaluation of Population Pharmacokinetic Models for Incorporation Into the Web-Accessible Population Pharmacokinetic Service - Hemoph... by Alanna McEneny‐King, Gary Foster, Alfonso Iorio, Andrea N. Edginton

    Published 2016
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  6. 6
    Dynamically simulating the interaction of midazolam and the CYP3A4 inhibitor itraconazole using individual coupled whole-body physiologically-based pharmacokinetic (WB-PBPK) models

    Dynamically simulating the interaction of midazolam and the CYP3A4 inhibitor itraconazole using individual coupled whole-body physiologically-based pharmacokinetic (WB-PBPK) models by M. Vossen, Michael Sevestre, Christoph Niederalt, In‐Jin Jang, Stefan Willmann, Andrea N. Edginton

    Published 2007
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  7. 7
    Sorafenib metabolism, transport, and enterohepatic recycling: physiologically based modeling and simulation in mice

    Sorafenib metabolism, transport, and enterohepatic recycling: physiologically based modeling and simulation in mice by Andrea N. Edginton, Eric I. Zimmerman, Aksana Vasilyeva, Sharyn D. Baker, John C. Panetta

    Published 2016
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  8. 8
    Development of a Pediatric Physiologically-Based Pharmacokinetic Model of Clindamycin Using Opportunistic Pharmacokinetic Data

    Development of a Pediatric Physiologically-Based Pharmacokinetic Model of Clindamycin Using Opportunistic Pharmacokinetic Data by Christoph P. Hornik, Huali Wu, Andrea N. Edginton, Kevin Watt, Michael Cohen‐Wolkowiez, Daniel González

    Published 2017
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  9. 9
    Development of a Web-Accessible Population Pharmacokinetic Service—Hemophilia (WAPPS-Hemo): Study Protocol

    Development of a Web-Accessible Population Pharmacokinetic Service—Hemophilia (WAPPS-Hemo): Study Protocol by Alfonso Iorio, Arun Keepanasseril, Gary Foster, Tamara Navarro, Alanna McEneny‐King, Andrea N. Edginton, Lehana Thabane

    Published 2016
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  10. 10
    Physiologically Based Pharmacokinetic Approach to Determine Dosing on Extracorporeal Life Support: Fluconazole in Children on <scp>ECMO</scp>

    Physiologically Based Pharmacokinetic Approach to Determine Dosing on Extracorporeal Life Support: Fluconazole in Children on <scp>ECMO</scp> by Kevin Watt, Michael Cohen‐Wolkowiez, Jeffrey S. Barrett, Michael Sevestre, Ping Zhao, Kim L. R. Brouwer, Andrea N. Edginton

    Published 2018
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  11. 11
    Characterizing Pharmacokinetics in Children With Obesity—Physiological, Drug, Patient, and Methodological Considerations

    Characterizing Pharmacokinetics in Children With Obesity—Physiological, Drug, Patient, and Methodological Considerations by Jacqueline G. Gerhart, Stephen J. Balevic, Jaydeep Sinha, Eliana M. Perrin, Jian Wang, Andrea N. Edginton, Daniel González

    Published 2022
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  12. 12
    Development of a Paediatric Population-Based Model of the Pharmacokinetics of Rivaroxaban

    Development of a Paediatric Population-Based Model of the Pharmacokinetics of Rivaroxaban by Stefan Willmann, Corina Becker, Rolf Burghaus, Katrin Coboeken, Andrea N. Edginton, Jörg Lippert, Hans‐Ulrich Siegmund, Kirstin Thelen, Wolfgang Mück

    Published 2013
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  13. 13
    Routine clinical care data for population pharmacokinetic modeling: the case for Fanhdi/Alphanate in hemophilia A patients

    Routine clinical care data for population pharmacokinetic modeling: the case for Fanhdi/Alphanate in hemophilia A patients by Pierre Chelle, Cindy H. T. Yeung, Santiago Bonanad, Juan Cristóbal Morales Muñoz, Margareth C. Ozelo, Juan Eduardo Megías‐Vericat, Alfonso Iorio, Jeffrey Spears, Roser Mir, Andrea N. Edginton

    Published 2019
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  14. 14
    Correction to: Routine clinical care data for population pharmacokinetic modeling: the case for Fanhdi/Alphanate in hemophilia A patients

    Correction to: Routine clinical care data for population pharmacokinetic modeling: the case for Fanhdi/Alphanate in hemophilia A patients by Pierre Chelle, Cindy H. T. Yeung, Santiago Bonanad, Juan Cristóbal Morales Muñoz, Margareth C. Ozelo, Juan Eduardo Megías‐Vericat, Alfonso Iorio, Jeffrey Spears, Roser Mir, Andrea N. Edginton

    Published 2019
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  15. 15
    Comparative pharmacokinetics of two extended half‐life FVIII concentrates (Eloctate and Adynovate) in adolescents with hemophilia A: Is there a difference?

    Comparative pharmacokinetics of two extended half‐life FVIII concentrates (Eloctate and Adynovate) in adolescents with hemophilia A: Is there a difference? by Manuel Carção, Pierre Chelle, Emily Clarke, Lussia Kim, Laura Tiseo, Massimo Morfini, Taneya Hossain, Margaret L. Rand, Christine Brown, Andrea N. Edginton, David Lillicrap, Alfonso Iorio, Victor S. Blanchette

    Published 2019
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  16. 16
    Integrated Electrochemical Aptamer Biosensing and Colorimetric pH Monitoring via Hydrogel Microneedle Assays for Assessing Antibiotic Treatment

    Integrated Electrochemical Aptamer Biosensing and Colorimetric pH Monitoring via Hydrogel Microneedle Assays for Assessing Antibiotic Treatment by Fatemeh Keyvani, Peyman GhavamiNejad, Mahmoud Ayman Saleh, Mohammad Soltani, Yusheng Zhao, Sadegh Sadeghzadeh, Arash Shakeri, Pierre Chelle, Hanjia Zheng, Fasih A. Rahman, Sarah Mahshid, Joe Quadrilatero, Praveen P. N. Rao, Andrea N. Edginton, Mahla Poudineh

    Published 2024
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  17. 17
    Open Systems Pharmacology Community—An Open Access, Open Source, Open Science Approach to Modeling and Simulation in Pharmaceutical Sciences

    Open Systems Pharmacology Community—An Open Access, Open Source, Open Science Approach to Modeling and Simulation in Pharmaceutical Sciences by Jörg Lippert, Rolf Burghaus, Andrea N. Edginton, Sebastian Frechen, Mats O. Karlsson, Andreas Kovar, Thorsten Lehr, Peter Milligan, Valerie Nock, Sergej Ramusovic, Matthew Riggs, Stephan Schaller, Jan Schlender, Stephan Schmidt, Michaël Sevestre, Erik Sjögren, Juri Solodenko, Alexander Staab, Donato Teutonico

    Published 2019
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  18. 18
    Performing and interpreting individual pharmacokinetic profiles in patients with Hemophilia A or B: Rationale and general considerations

    Performing and interpreting individual pharmacokinetic profiles in patients with Hemophilia A or B: Rationale and general considerations by Alfonso Iorio, Andrea N. Edginton, Victor S. Blanchette, Jan Blatný, Ana Boban, Marjon H. Cnossen, Peter W. Collins, Stacy E. Croteau, Katheljin Fischer, Daniel P. Hart, Shinya Ito, Joan Korth‐Bradley, Stefan Lethagen, David Lillicrap, Michael Makris, Ron A. A. Mathôt, Massimo Morfini, Ellis J. Neufeld, Jeffrey Spears

    Published 2018
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  19. 19
    Targeting Mitochondria with Avocatin B Induces Selective Leukemia Cell Death

    Targeting Mitochondria with Avocatin B Induces Selective Leukemia Cell Death by Eric A. Lee, Leonard Angka, Sarah-Grace Rota, Thomas Hanlon, Andrew Mitchell, Rose Hurren, Xiao Ming Wang, Marcela Gronda, Ezel Boyacı, Barbara Bojko, Mark D. Minden, Shrivani Sriskanthadevan, Alessandro Datti, Jeffery L. Wrana, Andrea N. Edginton, Janusz Pawliszyn, Jamie W. Joseph, Joe Quadrilatero, Aaron D. Schimmer, Paul A. Spagnuolo

    Published 2015
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