Search Results - Andrea Degasperi

  • Showing 1 - 17 results of 17
Refine Results
  1. 1
    Performance of objective functions and optimisation procedures for parameter estimation in system biology models

    Performance of objective functions and optimisation procedures for parameter estimation in system biology models by Andrea Degasperi, Dirk Fey, Boris Ν. Kholodenko

    Published 2017
    Get full text Get full text
    Artigo
    Save to List
    Saved in:
  2. 2
    Evaluating Strategies to Normalise Biological Replicates of Western Blot Data

    Evaluating Strategies to Normalise Biological Replicates of Western Blot Data by Andrea Degasperi, Marc R. Birtwistle, Natalia Volinsky, Jens Rauch, Walter Kölch, Boris Ν. Kholodenko

    Published 2014
    Get full text Get full text
    Artigo
    Save to List
    Saved in:
  3. 3
    Dramatic response of metastatic cutaneous angiosarcoma to an immune checkpoint inhibitor in a patient with xeroderma pigmentosum: whole-genome sequencing aids treatment decision in end-stage disease

    Dramatic response of metastatic cutaneous angiosarcoma to an immune checkpoint inhibitor in a patient with xeroderma pigmentosum: whole-genome sequencing aids treatment decision in... by Sophie Momen, Hiva Fassihi, Helen Davies, Christos Nikolaou, Andrea Degasperi, Catherine M. Stefanato, João M.L. Dias, Dhruba Dasgupta, Emma Craythorne, Robert Sarkany, Sophie Papa, Serena Nik‐Zainal

    Published 2019
    Get full text Get full text
    Artigo
    Save to List
    Saved in:
  4. 4
    Mitochondrial reactive oxygen species enhance AMP-activated protein kinase activation in the endothelium of patients with coronary artery disease and diabetes

    Mitochondrial reactive oxygen species enhance AMP-activated protein kinase activation in the endothelium of patients with coronary artery disease and diabetes by Ruth M. Mackenzie, Ian P. Salt, William H. Miller, Angela Logan, Hagar Ibrahim, Andrea Degasperi, Jane A. Dymott, Carlene A. Hamilton, Michael P. Murphy, Christian Delles, Anna F. Dominiczak

    Published 2012
    Get full text Get full text
    Artigo
    Save to List
    Saved in:
  5. 5
    A Compendium of Mutational Signatures of Environmental Agents

    A Compendium of Mutational Signatures of Environmental Agents by Jill E. Kucab, Xueqing Zou, Sandro Morganella, Madeleine Joel, Arjun S. Nanda, Eszter Nagy, Céline Gomez, Andrea Degasperi, Rebecca Harris, Stephen P. Jackson, Volker M. Arlt, David H. Phillips, Serena Nik‐Zainal

    Published 2019
    Get full text
    Artigo
    Save to List
    Saved in:
  6. 6
    A practical guide for mutational signature analysis in hematological malignancies

    A practical guide for mutational signature analysis in hematological malignancies by Francesco Maura, Andrea Degasperi, Ferran Nadeu, Daniel Leongamornlert, Helen Davies, Luiza Moore, Romina Royo, Bachisio Ziccheddu, Xosé S. Puente, Hervé Avet‐Loiseau, Peter J. Campbell, Serena Nik‐Zainal, Elı́as Campo, Nikhil C. Munshi, Niccolò Bolli

    Published 2019
    Get full text Get full text
    Artigo
    Save to List
    Saved in:
  7. 7
    A practical framework and online tool for mutational signature analyses show intertissue variation and driver dependencies

    A practical framework and online tool for mutational signature analyses show intertissue variation and driver dependencies by Andrea Degasperi, Tauanne Dias Amarante, Jan Czarnecki, Scott Shooter, Xueqing Zou, Dominik Głodzik, Sandro Morganella, Arjun S. Nanda, Cherif Badja, Ching Chiek Koh, Sophie Momen, Ilias Georgakopoulos-Soares, João M.L. Dias, Jamie Young, Yasin Memari, Helen Davies, Serena Nik‐Zainal

    Published 2020
    Get full text
    Artigo
    Save to List
    Saved in:
  8. 8
    Bistability in the Rac1, PAK, and RhoA Signaling Network Drives Actin Cytoskeleton Dynamics and Cell Motility Switches

    Bistability in the Rac1, PAK, and RhoA Signaling Network Drives Actin Cytoskeleton Dynamics and Cell Motility Switches by K. Byrne, Naser Monsefi, John C. Dawson, Andrea Degasperi, Jimi Wills, Natalia Volinsky, Maciej Dobrzyński, Marc R. Birtwistle, M. A. Tsyganov, Anatoly Kiyatkin, Katarzyna Kida, Andrew J. Finch, Neil O. Carragher, Walter Kölch, Lan K. Nguyen, Alex von Kriegsheim, Boris Ν. Kholodenko

    Published 2016
    Get full text
    Artigo
    Save to List
    Saved in:
  9. 9
    Whole-genome sequencing of triple-negative breast cancers in a population-based clinical study

    Whole-genome sequencing of triple-negative breast cancers in a population-based clinical study by Johan Staaf, Dominik Głodzik, Ana Bosch, Johan Vallon‐Christersson, Christel Reuterswärd, Jari Häkkinen, Andrea Degasperi, Tauanne Dias Amarante, Lao H. Saal, Cecilia Hegardt, Hilary Stobart, Anna Ehinger, Christer Larsson, Lisa Rydén, Niklas Loman, Martin Malmberg, Anders Kvist, Hans Ehrencrona, Helen Davies, Åke Borg, Serena Nik‐Zainal

    Published 2019
    Get full text
    Artigo
    Save to List
    Saved in:
  10. 10
    Homologous recombination DNA repair deficiency and PARP inhibition activity in primary triple negative breast cancer

    Homologous recombination DNA repair deficiency and PARP inhibition activity in primary triple negative breast cancer by Neha Chopra, Holly Tovey, Alex Pearson, Ros Cutts, Christy Toms, Paula Proszek, Michael Hubank, Mitch Dowsett, Andrew Dodson, Frances Daley, Divya Kriplani, Heidi Gevensleben, Helen Davies, Andrea Degasperi, Rebecca Roylance, Stephen Chan, Andrew Tutt, Anthony Skene, Abigail Evans, Judith M. Bliss, Serena Nik‐Zainal, Nicholas C. Turner

    Published 2020
    Get full text Get full text
    Artigo
    Save to List
    Saved in:
  11. 11
    Targeting the DNA Damage Response Pathways and Replication Stress in Colorectal Cancer

    Targeting the DNA Damage Response Pathways and Replication Stress in Colorectal Cancer by Erika Durinikova, Nicole M. Reilly, Kristi Buzo, Elisa Mariella, Rosaria Chilà, Annalisa Lorenzato, João M.L. Dias, Gaia Grasso, Federica Pisati, Simona Lamba, Giorgio Corti, Andrea Degasperi, Carlotta Cancelliere, Gianluca Mauri, Pietro Andrei, Michael Linnebacher, Silvia Marsoni, Salvatore Siena, Andrea Sartore‐Bianchi, Serena Nik‐Zainal, Federica Di Nicolantonio, Alberto Bardelli, Sabrina Arena

    Published 2022
    Get full text Get full text
    Artigo
    Save to List
    Saved in:
  12. 12
    Whole-genome sequencing reveals clinically relevant insights into the aetiology of familial breast cancers

    Whole-genome sequencing reveals clinically relevant insights into the aetiology of familial breast cancers by Kátia Nones, Julie Johnson, Felicity Newell, Ann‐Marie Patch, Heather Thorne, Stephen H. Kazakoff, Xavier Marc De Luca, Michael T. Parsons, Kaltin Ferguson, Lynne Reid, Amy E. McCart Reed, Sriganesh Srihari, Vanessa Lakis, Aimee L. Davidson, Pamela Mukhopadhyay, Oliver Holmes, Qian Xu, Scott Wood, Conrad Leonard, Jonathan Beesley, Jonathan M. Harris, Deborah E. Barnes, Andrea Degasperi, Mark A. Ragan, Amanda B. Spurdle, Kum Kum Khanna, Sunil R. Lakhani, John V. Pearson, Serena Nik‐Zainal, Georgia Chenevix‐Trench, Nicola Waddell, Peter T. Simpson

    Published 2019
    Get full text Get full text
    Artigo
    Save to List
    Saved in:
  13. 13
    Preclinical <i>In Vivo</i> Validation of the RAD51 Test for Identification of Homologous Recombination-Deficient Tumors and Patient Stratification

    Preclinical <i>In Vivo</i> Validation of the RAD51 Test for Identification of Homologous Recombination-Deficient Tumors and Patient Stratification by Benedetta Pellegrino, Andrea Herencia-Ropero, Alba Llop‐Guevara, Flaminia Pedretti, Alejandro Moles‐Fernández, Cristina Viaplana, Guillermo Villacampa, Marta Guzmán, Olga Rodríguez, Judit Grueso, José Jiménez, Enrique J. Arenas, Andrea Degasperi, João M.L. Dias, Josep V. Forment, Mark J. O’Connor, Olivier Déas, Stefano Cairo, Yinghui Zhou, Antonino Musolino, Carlos Caldas, Serena Nik‐Zainal, Robert B. Clarke, Paolo Nucíforo, Orland Dı́ez, Xavier Serres, Vicente Peg, Martín Espinosa-Bravo, Teresa Macarulla, Ana Oaknin, Joaquı́n Mateo, Joaquı́n Arribas, Rodrigo Dienstmann, Meritxell Bellet, Mafalda Oliveira, Cristina Saura, Sara Gutiérrez‐Enríquez, Judith Balmañà, Violeta Serra

    Published 2022
    Get full text Get full text
    Artigo
    Save to List
    Saved in:
  14. 14
    Genomic characterisation of hormone receptor-positive breast cancer arising in very young women

    Genomic characterisation of hormone receptor-positive breast cancer arising in very young women by Stephen J. Luen, Giuseppe Viale, Serena Nik‐Zainal, Peter Savas, Roswitha Kammler, Patrizia DellʼOrto, Olivia Biasi, Andrea Degasperi, L.C. Brown, István Láng, Gaëtan MacGrogan, Carlo Tondini, Meritxell Bellet, Federica Villa, Antônio Bernardo, Eva Ciruelos, Per Karlsson, Patrick Neven, José A. Martínez-Climent, Bettina Müller, Wolfram Jochum, Hervé Bonnefoi, Silvana Martino, Nancy E. Davidson, Charles E. Geyer, Stephen Chia, James N. Ingle, Robert L. Coleman, Christine Solbach, Beat Thürlimann, Marco Colleoni, Alan S. Coates, Aron Goldhirsch, Gini F. Fleming, Prudence A. Francis, Terence P. Speed, Meredith M. Regan, Sherene Loi

    Published 2023
    Get full text
    Artigo
    Save to List
    Saved in:
  15. 15
    Substitution mutational signatures in whole-genome–sequenced cancers in the UK population

    Substitution mutational signatures in whole-genome–sequenced cancers in the UK population by Andrea Degasperi, Xueqing Zou, Tauanne Dias Amarante, Andrea Martinez-Martinez, Ching Chiek Koh, João M.L. Dias, Laura Heskin, Lucia Chmelova, Giuseppe Rinaldi, Valerie Ya Wen Wang, Arjun S. Nanda, Aaron Bernstein, Sophie Momen, Jamie Young, D. Perez-Gil, Yasin Memari, Cherif Badja, Scott Shooter, Jan Czarnecki, Matthew A. Brown, Helen Davies, Serena Nik‐Zainal, John C. Ambrose, P. Arumugam, R. Bevers, Marta Bleda, F. Boardman-Pretty, C. R. Boustred, Helen Brittain, M. J. Caulfield, G. C. Chan, Tom Fowler, Adam Giess, Angela Hamblin, Stephen Henderson, Tim Hubbard, R. Jackson, J. Louise Jones, Dalia Kasperavičiūtė, Melis Kayikci, Athanasios Kousathanas, L. Lahnstein, S. E. A. Leigh, Ivone Leong, F. J. Lopez, F. Maleady-Crowe, Meriel McEntagart, Federico Minneci, Loukas Moutsianas, Michael Mueller, Nirupa Murugaesu, Anna C. Need, Peter O’Donovan, Chris A. Odhams, Christine Patch, D. Perez-Gil, Mariana Buongermino Pereira, J. Pullinger, T. Rahim, Augusto Rendon, T. Rogers, K. Savage, K. Sawant, Richard H. Scott, Afshan Siddiq, A. Sieghart, Sean Smith, Alona Sosinsky, Alexander Stuckey, M. Tanguy, Ana Lisa Taylor Tavares, Elaine Thomas, Simon R. Thompson, Arianna Tucci, M. J. Welland, Elena Williams, Katarzyna Witkowska, Scott Wood

    Published 2022
    Get full text
    Artigo
    Save to List
    Saved in:
  16. 16
    Spectrum of mutational signatures in T-cell lymphoma reveals a key role for UV radiation in cutaneous T-cell lymphoma

    Spectrum of mutational signatures in T-cell lymphoma reveals a key role for UV radiation in cutaneous T-cell lymphoma by Christine L. Jones, Andrea Degasperi, Vieri Grandi, Tauanne Dias Amarante, John C. Ambrose, Prabhu Arumugam, Emma L. Baple, Marta Bleda, F. Boardman-Pretty, Jeanne M. Boissiere, C. R. Boustred, Helen Brittain, Mark J. Caulfield, G. C. Chan, Clare Craig, Louise C. Daugherty, Anna de Burca, A. Devereau, Greg Elgar, Rebecca E. Foulger, Tom Fowler, Pedro Furió‐Tarí, Adam Giess, Joanne M. Hackett, Dina Halai, Angela Hamblin, Shirley Henderson, J. Holman, Tim Hubbard, Kristina Ibáñez, R. Jackson, J. Louise Jones, Dalia Kasperavičiūtė, Melis Kayikci, Athanasios Kousathanas, L. Lahnstein, Kay Lawson, S. E. A. Leigh, I. U. S. Leong, Javier Ferreiros, F. Maleady-Crowe, Joanne Mason, Ellen M. McDonagh, Loukas Moutsianas, Michael Mueller, Nirupa Murugaesu, Anna C. Need, Peter O’Donovan, Chris A. Odhams, Andrea Orioli, Christine Patch, Mariana Buongermino Pereira, D. Perez-Gil, Dimitris Polychronopoulos, J. Pullinger, T. Rahim, Augusto Rendon, Pablo Riesgo-Ferreiro, Tim Rogers, Mina Ryten, K. Savage, Kushmita Sawant, Richard H. Scott, Afshan Siddiq, A. Sieghart, Damian Smedley, Katherine R. Smith, Samuel C. Smith, Alona Sosinsky, William Spooner, Helen Stevens, Alexander Stuckey, Răzvan Sultana, M. Tanguy, Ellen Thomas, Simon R. Thompson, Carolyn Tregidgo, Arianna Tucci, Emma Walsh, Sarah A. Watters, M. J. Welland, Eleanor C Williams, Katarzyna Witkowska, S. M. Wood, Magdalena Zarowiecki, Tracey J. Mitchell, Serena Nik‐Zainal, Sean Whittaker

    Published 2021
    Get full text Get full text
    Revisão
    Save to List
    Saved in:
  17. 17
    A systematic CRISPR screen defines mutational mechanisms underpinning signatures caused by replication errors and endogenous DNA damage

    A systematic CRISPR screen defines mutational mechanisms underpinning signatures caused by replication errors and endogenous DNA damage by Xueqing Zou, Gene Ching Chiek Koh, Arjun S. Nanda, Andrea Degasperi, Katie Urgo, Theodoros I. Roumeliotis, Chukwuma A. Agu, Cherif Badja, Sophie Momen, Jamie Young, Tauanne Dias Amarante, Lucy Side, Glen Brice, Vanesa Pérez‐Alonso, Daniel Rueda, Céline Gomez, Wendy Bushell, Rebecca Harris, Jyoti S. Choudhary, John C. Ambrose, Prabhu Arumugam, Emma L. Baple, Marta Bleda, F. Boardman-Pretty, Jeanne M. Boissiere, C. R. Boustred, Helen Brittain, Mark J. Caulfield, G. C. Chan, Clare Craig, Louise C. Daugherty, Anna de Burca, A. Devereau, Greg Elgar, Rebecca E. Foulger, Tom Fowler, Pedro Furió‐Tarí, Adam Giess, Joanne M. Hackett, Dina Halai, Angela Hamblin, Bingyang Shi, J. Holman, Tim Hubbard, Kristina Ibáñez, Robert W. Jackson, J. Louise Jones, Dalia Kasperavičiūtė, Melis Kayikci, Athanasios Kousathanas, L. Lahnstein, Kay Lawson, S. E. A. Leigh, I. U. S. Leong, Javier Ferreiros, F. Maleady-Crowe, Joanne Mason, Ellen M. McDonagh, Loukas Moutsianas, Michael Mueller, Nirupa Murugaesu, Anna C. Need, Pter O’Donovan, Chris A. Odhams, Andrea Orioli, Christine Patch, Mariana Buongermino Pereira, D. Perez-Gil, Dimitris Polychronopoulos, J. Pullinger, T. Rahim, Augusto Rendon, Pablo Riesgo-Ferreiro, Tim Rogers, Mina Ryten, K. Savage, Kushmita Sawant, Richard H. Scott, Afshan Siddiq, A. Sieghart, Damian Smedley, Katherine R. Smith, Samuel C. Smith, Alona Sosinsky, William Spooner, Helen E. Stevens, Alexander Stuckey, Răzvan Sultana, M. Tanguy, Ellen Thomas, Simon R. Thompson, Carolyn Tregidgo, Arianna Tucci, Emma Walsh, Sarah A. Watters, M. J. Welland, Eleanor Williams, Katarzyna Witkowska, S. M. Wood, Magdalena Zarowiecki

    Published 2021
    Get full text
    Artigo
    Save to List
    Saved in:

Search Tools: