Rezultati - Amanda L. Robichaud

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  1. 1
    Rapid and direct control of target protein levels with VHL-recruiting dTAG molecules

    Rapid and direct control of target protein levels with VHL-recruiting dTAG molecules od Behnam Nabet, Fleur M. Ferguson, Bo Kyung A. Seong, Miljan Kuljanin, Alan L. Leggett, Mikaela L. Mohardt, Amanda L. Robichaud, Amy Saur Conway, Dennis L. Buckley, Joseph D. Mancias, James E. Bradner, Kimberly Stegmaier, Nathanael S. Gray

    Izdano 2020
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  2. 2
    Genome-scale CRISPR-Cas9 screen identifies druggable dependencies in <i>TP53</i> wild-type Ewing sarcoma

    Genome-scale CRISPR-Cas9 screen identifies druggable dependencies in <i>TP53</i> wild-type Ewing sarcoma od Björn Stolte, Amanda Balboni Iniguez, Neekesh V. Dharia, Amanda L. Robichaud, Amy Saur Conway, Ann M. Morgan, Gabriela Alexe, Nathan J. Schauer, Xiaoxi Liu, Gregory H. Bird, Aviad Tsherniak, Francisca Vázquez, Sara J. Buhrlage, Loren D. Walensky, Kimberly Stegmaier

    Izdano 2018
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  3. 3
    Targeting serine hydroxymethyltransferases 1 and 2 for T-cell acute lymphoblastic leukemia therapy

    Targeting serine hydroxymethyltransferases 1 and 2 for T-cell acute lymphoblastic leukemia therapy od Yana Pikman, Nicole Ocasio-Martinez, Gabriela Alexe, Boris Dimitrov, Samuel Kitara, Frances F. Diehl, Amanda L. Robichaud, Amy Saur Conway, Linda S. Ross, Angela Su, Frank Ling, Jun Qi, Giovanni Roti, Caroline A. Lewis, Alexandre Puissant, Matthew G. Vander Heiden, Kimberly Stegmaier

    Izdano 2021
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  4. 4
    Resistance Mechanisms to SYK Inhibition in Acute Myeloid Leukemia

    Resistance Mechanisms to SYK Inhibition in Acute Myeloid Leukemia od Anjali Cremer, Jana M. Ellegast, Gabriela Alexe, Elizabeth S. Frank, Linda S. Ross, S. Haihua Chu, Yana Pikman, Amanda L. Robichaud, Amy Goodale, Björn Häupl, Sebastian Mohr, Arati V. Rao, Alison R. Walker, James S. Blachly, Federica Piccioni, Scott A. Armstrong, John C. Byrd, Thomas Oellerich, Kimberly Stegmaier

    Izdano 2019
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  5. 5
    Unleashing Cell-Intrinsic Inflammation as a Strategy to Kill AML Blasts

    Unleashing Cell-Intrinsic Inflammation as a Strategy to Kill AML Blasts od Jana M. Ellegast, Gabriela Alexe, Amanda Hamze, Shan Lin, Hannah J. Uckelmann, Philipp J. Rauch, Maxim Pimkin, Linda S. Ross, Neekesh V. Dharia, Amanda L. Robichaud, Amy Saur Conway, Delan Khalid, Jennifer A. Perry, Mark Wunderlich, Lina Benajiba, Yana Pikman, Behnam Nabet, Nathanael S. Gray, Stuart H. Orkin, Kimberly Stegmaier

    Izdano 2022
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  6. 6
    A Combination CDK4/6 and IGF1R Inhibitor Strategy for Ewing Sarcoma

    A Combination CDK4/6 and IGF1R Inhibitor Strategy for Ewing Sarcoma od Lillian M. Guenther, Neekesh V. Dharia, Linda S. Ross, Amy Saur Conway, Amanda L. Robichaud, Jerrel L. Catlett, Caroline S. Wechsler, Elizabeth S. Frank, Amy Goodale, Alanna J. Church, Yuen‐Yi Tseng, Rajarshi Guha, Crystal McKnight, Katherine A. Janeway, Jesse S. Boehm, Jaume Mora, Mindy I. Davis, Gabriela Alexe, Federica Piccioni, Kimberly Stegmaier

    Izdano 2018
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  7. 7
    TRIM8 modulates the EWS/FLI oncoprotein to promote survival in Ewing sarcoma

    TRIM8 modulates the EWS/FLI oncoprotein to promote survival in Ewing sarcoma od Bo Kyung A. Seong, Neekesh V. Dharia, Shan Lin, Katherine A. Donovan, Shasha Chong, Amanda L. Robichaud, Amy Saur Conway, Amanda Hamze, Linda S. Ross, Gabriela Alexe, Biniam Adane, Behnam Nabet, Fleur M. Ferguson, Björn Stolte, Emily Jue Wang, Jialin Sun, Xavier Darzacq, Federica Piccioni, Nathanael S. Gray, Eric S. Fischer, Kimberly Stegmaier

    Izdano 2021
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  8. 8
    An <i>In Vivo</i> CRISPR Screening Platform for Prioritizing Therapeutic Targets in AML

    An <i>In Vivo</i> CRISPR Screening Platform for Prioritizing Therapeutic Targets in AML od Shan Lin, Clément Larrue, Nastassja K. Scheidegger, Bo Kyung A. Seong, Neekesh V. Dharia, Miljan Kuljanin, Caroline S. Wechsler, Guillaume Kugener, Amanda L. Robichaud, Amy Saur Conway, Thelma Mashaka, Sarah Mouche, Biniam Adane, Jeremy Ryan, Joseph D. Mancias, Scott T. Younger, Federica Piccioni, Lynn Lee, Mark Wunderlich, Anthony Letai, Jérôme Tamburini, Kimberly Stegmaier

    Izdano 2021
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  9. 9
    Resistance to Epigenetic-Targeted Therapy Engenders Tumor Cell Vulnerabilities Associated with Enhancer Remodeling

    Resistance to Epigenetic-Targeted Therapy Engenders Tumor Cell Vulnerabilities Associated with Enhancer Remodeling od Amanda Balboni Iniguez, Gabriela Alexe, Emily Jue Wang, Giovanni Roti, Sarvagna Patel, Liying Chen, Samuel Kitara, Amy Saur Conway, Amanda L. Robichaud, Björn Stolte, Pratiti Bandopadhayay, Amy Goodale, Sasha Pantel, Yenarae Lee, Dorian M. Cheff, Matthew D. Hall, Rajarshi Guha, Mindy I. Davis, Marie Ménard, Nicole Nasholm, William A. Weiss, Jun Qi, Rameen Beroukhim, Federica Piccioni, Cory M. Johannessen, Kimberly Stegmaier

    Izdano 2018
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  10. 10
    Transition to a mesenchymal state in neuroblastoma confers resistance to anti-GD2 antibody via reduced expression of ST8SIA1

    Transition to a mesenchymal state in neuroblastoma confers resistance to anti-GD2 antibody via reduced expression of ST8SIA1 od Nathaniel W. Mabe, Min Huang, Guillermo Nicolás Dalton, Gabriela Alexe, Daniel A. Schaefer, Anna C. Geraghty, Amanda L. Robichaud, Amy Saur Conway, Delan Khalid, Marius Marc-Daniel Mader, Julia A. Belk, Kenneth N. Ross, Michal Sheffer, Miles H. Linde, Nghi Ly, Winnie Yao, Maria Caterina Rotiroti, Benjamin Smith, Marius Wernig, Carolyn R. Bertozzi, Michelle Monje, Constantine S. Mitsiades, Ravindra Majeti, Ansuman T. Satpathy, Kimberly Stegmaier, Robbie G. Majzner

    Izdano 2022
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  11. 11
    STAG2 loss rewires oncogenic and developmental programs to promote metastasis in Ewing sarcoma

    STAG2 loss rewires oncogenic and developmental programs to promote metastasis in Ewing sarcoma od Biniam Adane, Gabriela Alexe, Bo Kyung A. Seong, Diana Lu, Elizabeth Hwang, Denes Hnisz, Caleb A. Lareau, Linda S. Ross, Shan Lin, Filemon S. Dela Cruz, Melissa Richardson, Abraham S. Weintraub, Sarah Wang, Amanda Balboni Iniguez, Neekesh V. Dharia, Amy Saur Conway, Amanda L. Robichaud, Benjamin Tanenbaum, John M. Krill-Burger, Francisca Vázquez, Monica Schenone, Jason N. Berman, Andrew L. Kung, Steven A. Carr, Martin J. Aryee, Richard A. Young, Brian D. Crompton, Kimberly Stegmaier

    Izdano 2021
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  12. 12
    EP300 Selectively Controls the Enhancer Landscape of <i>MYCN</i>-Amplified Neuroblastoma

    EP300 Selectively Controls the Enhancer Landscape of <i>MYCN</i>-Amplified Neuroblastoma od Adam D. Durbin, Tingjian Wang, Virangika K. Wimalasena, Mark W. Zimmerman, Deyao Li, Neekesh V. Dharia, Luca Mariani, Noha A.M. Shendy, Stephanie Nance, Anand G. Patel, Ying Shao, Maya Mundada, Lily Maxham, Paul M.C. Park, Logan H. Sigua, Ken Morita, Amy Saur Conway, Amanda L. Robichaud, Antonio R. Pérez‐Atayde, Melissa J. Bikowitz, Taylor R. Quinn, Olaf Wiest, John Easton, E. Schönbrunn, Martha L. Bulyk, Brian J. Abraham, Kimberly Stegmaier, A. Thomas Look, Jun Qi

    Izdano 2021
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  13. 13
    Matched Targeted Therapy for Pediatric Patients with Relapsed, Refractory, or High-Risk Leukemias: A Report from the LEAP Consortium

    Matched Targeted Therapy for Pediatric Patients with Relapsed, Refractory, or High-Risk Leukemias: A Report from the LEAP Consortium od Yana Pikman, Sarah K. Tasian, Maria Luisa Sulis, Kristen E. Stevenson, Traci M. Blonquist, Beth Apsel Winger, Todd M. Cooper, Melinda Pauly, Kelly W. Maloney, Michael J. Burke, Patrick A. Brown, Nathan Gossai, Jennifer L. McNeer, Neerav Shukla, Peter D. Cole, Justine M. Kahn, Jing Chen, Matthew J. Barth, Jeffrey A. Magee, Lisa Gennarini, Asmani A. Adhav, Catherine Clinton, Nicole Ocasio-Martinez, Giacomo Gotti, Yuting Li, Shan Lin, Alma Imamović, Cristina E. Tognon, Tasleema Patel, Haley L. Faust, Cristina F. Contreras, Anjali Cremer, Wilian A. Cortopassi, Diego Garrido Ruiz, Matthew P. Jacobson, Neekesh V. Dharia, Angela Su, Amanda L. Robichaud, Amy Saur Conway, Katherine Tarlock, Elliot Stieglitz, Andrew E. Place, Alexandre Puissant, Stephen P. Hunger, Annette S. Kim, Neal I. Lindeman, Lia Gore, Katherine A. Janeway, Lewis B. Silverman, Jeffrey W. Tyner, Marian H. Harris, Mignon L. Loh, Kimberly Stegmaier

    Izdano 2021
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