Hakutulokset - Altmann, Karl-Heinz

The chemistry and biology of mycolactones Tekijä Gehringer, Matthias, Altmann, Karl-Heinz

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Ring-Closing Metathesis Approaches towards the Total Synthesis of Rhizoxins Tekijä Liniger, Marc, Neuhaus, Christian M., Altmann, Karl-Heinz

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Synthesis and Antimycobacterial Activity of 2,1′-Dihydropyridomycins Tekijä Horlacher, Oliver P., Hartkoorn, Ruben C., Cole, Stewart T., Altmann, Karl-Heinz

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An Antigen Capture Assay for the Detection of Mycolactone, the Polyketide Toxin of Mycobacterium ulcerans Tekijä Warryn, Louisa, Dangy, Jean-Pierre, Gersbach, Philipp, Gehringer, Matthias, Altmann, Karl-Heinz, Pluschke, Gerd

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Structure-Activity Relationship Studies on the Macrolide Exotoxin Mycolactone of Mycobacterium ulcerans Tekijä Scherr, Nicole, Gersbach, Philipp, Dangy, Jean-Pierre, Bomio, Claudio, Li, Jun, Altmann, Karl-Heinz, Pluschke, Gerd

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Zampanolide, a Microtubule-Stabilizing Agent, Is Active in Resistant Cancer Cells and Inhibits Cell Migration Tekijä Field, Jessica J., Northcote, Peter T., Paterson, Ian, Altmann, Karl-Heinz, Díaz, J. Fernando, Miller, John H.

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Synthesis, Microtubule-Binding Affinity, and Antiproliferative Activity of New Epothilone Analogs and of an EGFR-Targeted Epothilone-Peptide Conjugate Tekijä Gaugaz, Fabienne Zdenka, Chicca, Andrea, Redondo-Horcajo, Mariano, Barasoain, Isabel, Díaz, J. Fernando, Altmann, Karl-Heinz

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The LAT1 inhibitor JPH203 reduces growth of thyroid carcinoma in a fully immunocompetent mouse model Tekijä Häfliger, Pascal, Graff, Julien, Rubin, Matthias, Stooss, Amandine, Dettmer, Matthias S., Altmann, Karl-Heinz, Gertsch, Jürg, Charles, Roch-Philippe

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Kinase Inhibition by Deoxy Analogues of the Resorcylic Lactone L-783277 Tekijä Liniger, Marc, Neuhaus, Christian, Hofmann, Tatjana, Fransioli-Ignazio, Luca, Jordi, Michel, Drueckes, Peter, Trappe, Jörg, Fabbro, Doriano, Altmann, Karl-Heinz

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Beta-caryophyllene is a dietary cannabinoid Tekijä Gertsch, Jürg, Leonti, Marco, Raduner, Stefan, Racz, Ildiko, Chen, Jian-Zhong, Xie, Xiang-Qun, Altmann, Karl-Heinz, Karsak, Meliha, Zimmer, Andreas

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Development of an ELISA for the quantification of mycolactone, the cytotoxic macrolide toxin of Mycobacterium ulcerans Tekijä Warryn, Louisa, Dangy, Jean-Pierre, Gersbach, Philipp, Gehringer, Matthias, Schäfer, Anja, Ruf, Marie-Thérèse, Ruggli, Nicolas, Altmann, Karl-Heinz, Pluschke, Gerd

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Mechanism of substrate transport and inhibition of the human LAT1-4F2hc amino acid transporter Tekijä Yan, Renhong, Li, Yaning, Müller, Jennifer, Zhang, Yuanyuan, Singer, Simon, Xia, Lu, Zhong, Xinyue, Gertsch, Jürg, Altmann, Karl-Heinz, Zhou, Qiang

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Synthesis, Biological Profiling and Determination of the Tubulin-Bound Conformation of 12-Aza-Epothilones (Azathilones) Tekijä Jantsch, Andrea, Nieto, Lidia, Gertsch, Jürg, Rodríguez-Salarichs, Javier, Matesanz, Ruth, Jiménez-Barbero, Jesús, Díaz, J. Fernando, Canales, Ángeles, Altmann, Karl-Heinz

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Towards a new tuberculosis drug: pyridomycin – nature's isoniazid Tekijä Hartkoorn, Ruben C, Sala, Claudia, Neres, João, Pojer, Florence, Magnet, Sophie, Mukherjee, Raju, Uplekar, Swapna, Boy-Röttger, Stefanie, Altmann, Karl-Heinz, Cole, Stewart T

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Antibody-Mediated Neutralization of the Exotoxin Mycolactone, the Main Virulence Factor Produced by Mycobacterium ulcerans Tekijä Dangy, Jean-Pierre, Scherr, Nicole, Gersbach, Philipp, Hug, Melanie N., Bieri, Raphael, Bomio, Claudio, Li, Jun, Huber, Sylwia, Altmann, Karl-Heinz, Pluschke, Gerd

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RNA polymerase motions during promoter melting Tekijä Feklistov, Andrey, Bae, Brian, Hauver, Jesse, Lass-Napiorkowska, Agnieszka, Kalesse, Markus, Glaus, Florian, Altmann, Karl-Heinz, Heyduk, Tomasz, Landick, Robert, Darst, Seth A.

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Small molecule inhibitors provide insights into the relevance of LAT1 and LAT2 in materno‐foetal amino acid transport Tekijä Zaugg, Jonas, Huang, Xiao, Ziegler, Fabian, Rubin, Matthias, Graff, Julien, Müller, Jennifer, Moser‐Hässig, Ruedi, Powell, Theresa, Gertsch, Jürg, Altmann, Karl‐Heinz, Albrecht, Christiane

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Sequence-specific antitumor activity of a phosphorothioate oligodeoxyribonucleotide targeted to human C-raf kinase supports an antisense mechanism of action in vivo Tekijä Monia, Brett P., Sasmor, Henri, Johnston, Joseph F., Freier, Susan M., Lesnik, Elena A., Muller, Marcel, Geiger, Thomas, Altmann, Karl-Heinz, Moser, Heinz, Fabbro, Doriano

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A new tubulin-binding site and pharmacophore for microtubule-destabilizing anticancer drugs Tekijä Prota, Andrea E., Bargsten, Katja, Diaz, J. Fernando, Marsh, May, Cuevas, Carmen, Liniger, Marc, Neuhaus, Christian, Andreu, Jose M., Altmann, Karl-Heinz, Steinmetz, Michel O.

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High affinity and covalent-binding microtubule stabilizing agents show activity in chemotherapy-resistant acute myeloid leukemia cells Tekijä Pera, Benet, Calvo-Vidal, M. Nieves, Ambati, Srikanth, Jordi, Michel, Kahn, Alissa, Díaz, J. Fernando, Fang, Weishuo, Altmann, Karl-Heinz, Cerchietti, Leandro, Moore, Malcolm A.S.

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