Resultats de la cerca - Alexandros Tzatsos

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  1. 1
    Raptor Binds the SAIN (Shc and IRS-1 NPXY Binding) Domain of Insulin Receptor Substrate-1 (IRS-1) and Regulates the Phosphorylation of IRS-1 at Ser-636/639 by mTOR

    Raptor Binds the SAIN (Shc and IRS-1 NPXY Binding) Domain of Insulin Receptor Substrate-1 (IRS-1) and Regulates the Phosphorylation of IRS-1 at Ser-636/639 by mTOR per Alexandros Tzatsos

    Publicat 2009
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  2. 2
    Energy Depletion Inhibits Phosphatidylinositol 3-Kinase/Akt Signaling and Induces Apoptosis via AMP-activated Protein Kinase-dependent Phosphorylation of IRS-1 at Ser-794

    Energy Depletion Inhibits Phosphatidylinositol 3-Kinase/Akt Signaling and Induces Apoptosis via AMP-activated Protein Kinase-dependent Phosphorylation of IRS-1 at Ser-794 per Alexandros Tzatsos, Philip N. Tsichlis

    Publicat 2007
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  3. 3
    Nutrients Suppress Phosphatidylinositol 3-Kinase/Akt Signaling via Raptor-Dependent mTOR-Mediated Insulin Receptor Substrate 1 Phosphorylation

    Nutrients Suppress Phosphatidylinositol 3-Kinase/Akt Signaling via Raptor-Dependent mTOR-Mediated Insulin Receptor Substrate 1 Phosphorylation per Alexandros Tzatsos, Konstantin V. Kandror

    Publicat 2005
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  4. 4
    Ndy1/KDM2B immortalizes mouse embryonic fibroblasts by repressing the <i>Ink4a</i> / <i>Arf</i> locus

    Ndy1/KDM2B immortalizes mouse embryonic fibroblasts by repressing the <i>Ink4a</i> / <i>Arf</i> locus per Alexandros Tzatsos, Raymond Pfau, Sotirios C. Kampranis, Philip N. Tsichlis

    Publicat 2009
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  5. 5
    Histone demethylase KDM2B regulates lineage commitment in normal and malignant hematopoiesis

    Histone demethylase KDM2B regulates lineage commitment in normal and malignant hematopoiesis per Jaclyn Andricovich, Kai Yan, Weiqun Peng, Adlen Foudi, Alexandros Tzatsos

    Publicat 2016
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  6. 6
    Predicting CTCF-mediated chromatin interactions by integrating genomic and epigenomic features

    Predicting CTCF-mediated chromatin interactions by integrating genomic and epigenomic features per Kai Yan, Jaclyn Andricovich, Zhouhao Zeng, Jun Zhu, Alexandros Tzatsos, Weiqun Peng

    Publicat 2018
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  7. 7
    Loss of KDM6A Activates Super-Enhancers to Induce Gender-Specific Squamous-like Pancreatic Cancer and Confers Sensitivity to BET Inhibitors

    Loss of KDM6A Activates Super-Enhancers to Induce Gender-Specific Squamous-like Pancreatic Cancer and Confers Sensitivity to BET Inhibitors per Jaclyn Andricovich, Stephanie Perkail, Kai Yan, Nicole Casasanta, Weiqun Peng, Alexandros Tzatsos

    Publicat 2018
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  8. 8
    Members of a family of JmjC domain-containing oncoproteins immortalize embryonic fibroblasts via a JmjC domain-dependent process

    Members of a family of JmjC domain-containing oncoproteins immortalize embryonic fibroblasts via a JmjC domain-dependent process per Raymond Pfau, Alexandros Tzatsos, Sotirios C. Kampranis, Oksana B. Serebrennikova, S E Bear, Philip N. Tsichlis

    Publicat 2008
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  9. 9
    Lysine-specific Demethylase 2B (KDM2B)-let-7-Enhancer of Zester Homolog 2 (EZH2) Pathway Regulates Cell Cycle Progression and Senescence in Primary Cells

    Lysine-specific Demethylase 2B (KDM2B)-let-7-Enhancer of Zester Homolog 2 (EZH2) Pathway Regulates Cell Cycle Progression and Senescence in Primary Cells per Alexandros Tzatsos, Polina Paskaleva, Stephania Lymperi, Gianmarco Contino, Svetlana Stoykova, Zhao Chen, Kwok‐Kin Wong, Nabeel Bardeesy

    Publicat 2011
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  10. 10
    Targeting IL13Ralpha2 activates STAT6-TP63 pathway to suppress breast cancer lung metastasis

    Targeting IL13Ralpha2 activates STAT6-TP63 pathway to suppress breast cancer lung metastasis per Panagiotis Papageorgis, Sait Öztürk, Arthur W. Lambert, Christiana M. Neophytou, Alexandros Tzatsos, Chen Khuan Wong, Sam Thiagalingam, Andreas I. Constantinou

    Publicat 2015
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  11. 11
    Hippo Signaling Regulates Differentiation and Maintenance in the Exocrine Pancreas

    Hippo Signaling Regulates Differentiation and Maintenance in the Exocrine Pancreas per Tao Gao, Dawang Zhou, Chenghua Yang, Tarjinder Singh, Alfredo Penzo‐Méndez, Ravikanth Maddipati, Alexandros Tzatsos, Nabeel Bardeesy, Joseph Avruch, Ben Z. Stanger

    Publicat 2013
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  12. 12
    KDM2B promotes pancreatic cancer via Polycomb-dependent and -independent transcriptional programs

    KDM2B promotes pancreatic cancer via Polycomb-dependent and -independent transcriptional programs per Alexandros Tzatsos, Polina Paskaleva, Francesco Ferrari, Vikram Deshpande, Svetlana Stoykova, Gianmarco Contino, Kwok‐Kin Wong, Fei Lan, Patrick Trojer, Peter J. Park, Nabeel Bardeesy

    Publicat 2013
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  13. 13
    <i>STAT3</i> Plays a Critical Role in <i>KRAS</i>-Induced Pancreatic Tumorigenesis

    <i>STAT3</i> Plays a Critical Role in <i>KRAS</i>-Induced Pancreatic Tumorigenesis per Ryan B. Corcoran, Gianmarco Contino, Vikram Deshpande, Alexandros Tzatsos, Claudius Conrad, Cyril H. Benes, David E. Levy, Jeffrey Settleman, Jeffrey A. Engelman, Nabeel Bardeesy

    Publicat 2011
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  14. 14
    The Lkb1 metabolic sensor maintains haematopoietic stem cell survival

    The Lkb1 metabolic sensor maintains haematopoietic stem cell survival per Sushma Gurumurthy, Stephanie Z. Xie, Brinda Alagesan, Judith Kim, Rushdia Z. Yusuf, Borja Sáez, Alexandros Tzatsos, Fatih Ozsolak, Patrice M. Milos, Francesco Ferrari, Peter J. Park, Orian S. Shirihai, David T. Scadden, Nabeel Bardeesy

    Publicat 2010
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  15. 15
    miR-137 mediates the functional link between c-Myc and EZH2 that regulates cisplatin resistance in ovarian cancer

    miR-137 mediates the functional link between c-Myc and EZH2 that regulates cisplatin resistance in ovarian cancer per Jing Sun, Xin Cai, Mingo M. H. Yung, Wei Zhou, Jing Li, Yi Zhang, Zhuqing Li, Stephanie S. Liu, Any Cheung, Hys Ngan, Yiliang Li, Zhijun Dai, Kai Yan, Alexandros Tzatsos, Weiqun Peng, David W. Chan, Wenge Zhu

    Publicat 2018
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  16. 16
    Vitamin D Deficiency Promotes Liver Tumor Growth in Transforming Growth Factor-β/Smad3-Deficient Mice Through Wnt and Toll-like Receptor 7 Pathway Modulation

    Vitamin D Deficiency Promotes Liver Tumor Growth in Transforming Growth Factor-β/Smad3-Deficient Mice Through Wnt and Toll-like Receptor 7 Pathway Modulation per Jian Chen, Lior H. Katz, Nina M. Muñoz, Shoujun Gu, Ji-Hyun Shin, Wilma Jogunoori, Mi‐Hye Lee, Mitchell Belkin, Sang-Bae Kim, Jon White, Jaclyn Andricovich, Alexandros Tzatsos, Shulin Li, Sang Soo Kim, Kirti Shetty, Bibhuti Mishra, Asif Rashid, Ju–Seog Lee, Lopa Mishra

    Publicat 2016
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  17. 17
    DUOXA1-mediated ROS production promotes cisplatin resistance by activating ATR-Chk1 pathway in ovarian cancer

    DUOXA1-mediated ROS production promotes cisplatin resistance by activating ATR-Chk1 pathway in ovarian cancer per Yunxiao Meng, Chi‐Wei Chen, Mingo M. H. Yung, Wei Sun, Jing Sun, Zhuqing Li, Jing Li, Zongzhu Li, Wei Zhou, Stephanie S. Liu, Any Cheung, Hys Ngan, John Braisted, Kai Yan, Weiqun Peng, Alexandros Tzatsos, Yiliang Li, Zhijun Dai, Wei Zheng, David W. Chan, Wenge Zhu

    Publicat 2018
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