Résultats de la recherche - Alexander E. Perl
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Single-Cell Pharmacodynamic Monitoring of S6 Ribosomal Protein Phosphorylation in AML Blasts during a Clinical Trial Combining the mTOR Inhibitor Sirolimus and Intensive Chemothera... par Alexander E. Perl, Margaret Kasner, Doris Shank, Selina M. Luger, Martin Carroll
Publié 2011Artigo -
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Phase I study of UCN-01 and perifosine in patients with relapsed and refractory acute leukemias and high-risk myelodysplastic syndrome par Ivana Gojo, Alexander E. Perl, Selina M. Luger, Maria R. Baer, Kelly J. Norsworthy, Kenneth S. Bauer, Michael Tidwell, Stephanie Fleckinger, Martin Carroll, Edward A. Sausville
Publié 2013Artigo -
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Gilteritinib induces differentiation in relapsed and refractory FLT3-mutated acute myeloid leukemia par Christine M. McMahon, Jonathan Canaani, Bryan Rea, Rachel L. Sargent, Julianne Qualtieri, Christopher D. Watt, Jennifer J.D. Morrissette, Martin Carroll, Alexander E. Perl
Publié 2019Artigo -
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Phase 2b study of 2 dosing regimens of quizartinib monotherapy in FLT3-ITD–mutated, relapsed or refractory AML par Jorge E. Cortés, Martin S. Tallman, Gary J. Schiller, Denise Trone, Guy Gammon, Stuart L. Goldberg, Alexander E. Perl, Jean-Pierre Marie, Giovanni Martinelli, Hagop M. Kantarjian, Mark J. Levis
Publié 2018Artigo -
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A Genome-Wide CRISPR Screen Identifies Genes Critical for Resistance to FLT3 Inhibitor AC220 par Panpan Hou, Chao Wu, Yuchen Wang, Rui Qi, Dheeraj Bhavanasi, Zhixiang Zuo, Cédric Dos Santos, Shuliang Chen, Yu Chen, Hong Zheng, Hong Wang, Alexander E. Perl, Deyin Guo, Jian Huang
Publié 2017Artigo -
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A next-generation sequencing–based assay for minimal residual disease assessment in AML patients with FLT3-ITD mutations par Mark J. Levis, Alexander E. Perl, Jessica K. Altman, Christopher D. Gocke, Erkut Bahceci, Jason E. Hill, Chaofeng Liu, Zhiyi Xie, Andrew R. Carson, Valerie McClain, Timothy T. Stenzel, Jeffrey E. Miller
Publié 2018Artigo -
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Oncogene-independent BCR-like signaling adaptation confers drug resistance in Ph-like ALL par Christian Hurtz, Gerald Wertheim, Joseph P. Loftus, Daniel Blumenthal, Anne W. Lehman, Yong Li, Asen Bagashev, Bryan Manning, Katherine D. Cummins, Janis K. Burkhardt, Alexander E. Perl, Martin Carroll, Sarah K. Tasian
Publié 2020Artigo -
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Terminal myeloid differentiation in vivo is induced by FLT3 inhibition in FLT3/ITD AML par Amy Sexauer, Alexander E. Perl, Xiaochuan Yang, Michael J. Borowitz, Christopher D. Gocke, Trivikram Rajkhowa, Christian Thiede, Mark G. Frattini, Grant E. Nybakken, Keith W. Pratz, Judith E. Karp, B. Douglas Smith, Mark J. Levis
Publié 2012Artigo -
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Updated Results from a Phase 1 Study of Gilteritinib in Combination with Induction and Consolidation Chemotherapy in Subjects with Newly Diagnosed Acute Myeloid Leukemia (AML) par Keith W. Pratz, Mohamad Cherry, Jessica K. Altman, Brenda Cooper, José C. Cruz, Joseph G. Jurcic, Mark J. Levis, Tara L. Lin, Alexander E. Perl, Nikolai A. Podoltsev, Gary J. Schiller, Chaofeng Liu, Erkut Bahceci
Publié 2018Artigo
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