検索結果 - Alexander, Ian E

Accepting Risk in Clinical Research: Is the Gene Therapy Field Becoming Too Risk-averse? 著者: Deakin, Claire T, Alexander, Ian E, Kerridge, Ian

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Gene therapy for monogenic liver diseases: clinical successes, current challenges and future prospects 著者: Baruteau, Julien, Waddington, Simon N., Alexander, Ian E., Gissen, Paul

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Sexually Dimorphic Patterns of Episomal rAAV Genome Persistence in the Adult Mouse Liver and Correlation With Hepatocellular Proliferation 著者: Dane, Allison P, Cunningham, Sharon C, Graf, Nicole S, Alexander, Ian E

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Gene Therapy Researchers' Assessments Of Risks And Perceptions Of Risk Acceptability In Clinical Trials 著者: Deakin, Claire T., Alexander, Ian E., Hooker, Cliff A., Kerridge, Ian H.

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Ub-ISAP: a streamlined UNIX pipeline for mining unique viral vector integration sites from next generation sequencing data 著者: Kamboj, Atul, Hallwirth, Claus V., Alexander, Ian E., McCowage, Geoffrey B., Kramer, Belinda

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Persistent expression of human clotting factor IX from mouse liver after intravenous injection of adeno-associated virus vectors 著者: Koeberl, Dwight D., Alexander, Ian E., Halbert, Christine L., Russell, David W., Miller, A. Dusty

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AAV2/8-mediated Correction of OTC Deficiency Is Robust in Adult but Not Neonatal Spf(ash) Mice 著者: Cunningham, Sharon C, Spinoulas, Afroditi, Carpenter, Kevin H, Wilcken, Bridget, Kuchel, Philip W, Alexander, Ian E

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Myoblast sensitivity and fibroblast insensitivity to osteogenic conversion by BMP-2 correlates with the expression of Bmpr-1a 著者: Liu, Renjing, Ginn, Samantha L, Lek, Monkol, North, Kathryn N, Alexander, Ian E, Little, David G, Schindeler, Aaron

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Human Induced Pluripotent Stem Cells Derived Under Feeder-Free Conditions Display Unique Cell Cycle and DNA Replication Gene Profiles 著者: Chung, Henry C.Y., Lin, Ruby C.Y., Logan, Grant J., Alexander, Ian E., Sachdev, Perminder S., Sidhu, Kuldip S.

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Induction and Prevention of Severe Hyperammonemia in the spf(ash) Mouse Model of Ornithine Transcarbamylase Deficiency Using shRNA and rAAV-mediated Gene Delivery 著者: Cunningham, Sharon C, Kok, Cindy Y, Dane, Allison P, Carpenter, Kevin, Kizana, Eddy, Kuchel, Philip W, Alexander, Ian E

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A bioinformatic pipeline for simulating viral integration data 著者: Scott, Suzanne, Grigson, Susanna, Hartkopf, Felix, Hallwirth, Claus V., Alexander, Ian E., Bauer, Denis C., Wilson, Laurence O.W.

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HeLa cells cocultured with peripheral blood lymphocytes acquire an immuno-inhibitory phenotype through up-regulation of indoleamine 2,3-dioxygenase activity 著者: Logan, Grant J, Smyth, Christine M F, Earl, John W, Zaikina, Irina, Rowe, Peter B, Smythe, Jason A, Alexander, Ian E

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Impact of next-generation sequencing error on analysis of barcoded plasmid libraries of known complexity and sequence 著者: Deakin, Claire T., Deakin, Jeffrey J., Ginn, Samantha L., Young, Paul, Humphreys, David, Suter, Catherine M., Alexander, Ian E., Hallwirth, Claus V.

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Liver‐Targeted Angiotensin Converting Enzyme 2 Therapy Inhibits Chronic Biliary Fibrosis in Multiple Drug‐Resistant Gene 2‐Knockout Mice 著者: Rajapaksha, Indu G., Gunarathne, Lakmie S., Asadi, Khashayar, Cunningham, Sharon C., Sharland, Alexandra, Alexander, Ian E., Angus, Peter W., Herath, Chandana B.

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Performance of Cardiotropic rAAV Vectors Is Dependent on Production Method 著者: Rao, Renuka, Farraha, Melad, Logan, Grant J., Igoor, Sindhu, Kok, Cindy Y., Chong, James J. H., Alexander, Ian E., Kizana, Eddy

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Mitochondrial Respiratory Chain Hepatopathies: Role of Liver Transplantation. A Case Series of Five Patients 著者: De Greef, Elisabeth, Christodoulou, John, Alexander, Ian E, Shun, Albert, O’Loughlin, Edward V, Thorburn, David R, Jermyn, Vicki, Stormon, Michael O

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Angiotensin Converting Enzyme‐2 Therapy Improves Liver Fibrosis and Glycemic Control in Diabetic Mice With Fatty Liver 著者: Rajapaksha, Indu G., Gunarathne, Lakmie S., Asadi, Khashayar, Laybutt, Ross, Andrikopoulous, Sof, Alexander, Ian E., Watt, Mathew J., Angus, Peter W., Herath, Chandana B.

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Adeno-associated Virus-mediated Rescue of Neonatal Lethality in Argininosuccinate Synthetase-deficient Mice 著者: Kok, Cindy Y, Cunningham, Sharon C, Carpenter, Kevin H, Dane, Allison P, Siew, Susan M, Logan, Grant J, Kuchel, Philip W, Alexander, Ian E

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Use of a Hybrid Adeno-Associated Viral Vector Transposon System to Deliver the Insulin Gene to Diabetic NOD Mice 著者: La, Que T., Ren, Binhai, Logan, Grant J., Cunningham, Sharon C., Khandekar, Neeta, Nassif, Najah T., O’Brien, Bronwyn A., Alexander, Ian E., Simpson, Ann M.

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Selection and evaluation of clinically relevant AAV variants in a xenograft liver model 著者: Lisowski, Leszek, Dane, Allison P., Chu, Kirk, Zhang, Yue, Cunningham, Sharon C., Wilson, Elizabeth M., Nygaard, Sean, Grompe, Markus, Alexander, Ian E., Kay, Mark A.

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