Rezultati pretrage - Alexander, Ian E

Accepting Risk in Clinical Research: Is the Gene Therapy Field Becoming Too Risk-averse? od Deakin, Claire T, Alexander, Ian E, Kerridge, Ian

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Gene therapy for monogenic liver diseases: clinical successes, current challenges and future prospects od Baruteau, Julien, Waddington, Simon N., Alexander, Ian E., Gissen, Paul

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Sexually Dimorphic Patterns of Episomal rAAV Genome Persistence in the Adult Mouse Liver and Correlation With Hepatocellular Proliferation od Dane, Allison P, Cunningham, Sharon C, Graf, Nicole S, Alexander, Ian E

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Gene Therapy Researchers' Assessments Of Risks And Perceptions Of Risk Acceptability In Clinical Trials od Deakin, Claire T., Alexander, Ian E., Hooker, Cliff A., Kerridge, Ian H.

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Ub-ISAP: a streamlined UNIX pipeline for mining unique viral vector integration sites from next generation sequencing data od Kamboj, Atul, Hallwirth, Claus V., Alexander, Ian E., McCowage, Geoffrey B., Kramer, Belinda

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Persistent expression of human clotting factor IX from mouse liver after intravenous injection of adeno-associated virus vectors od Koeberl, Dwight D., Alexander, Ian E., Halbert, Christine L., Russell, David W., Miller, A. Dusty

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AAV2/8-mediated Correction of OTC Deficiency Is Robust in Adult but Not Neonatal Spf(ash) Mice od Cunningham, Sharon C, Spinoulas, Afroditi, Carpenter, Kevin H, Wilcken, Bridget, Kuchel, Philip W, Alexander, Ian E

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Myoblast sensitivity and fibroblast insensitivity to osteogenic conversion by BMP-2 correlates with the expression of Bmpr-1a od Liu, Renjing, Ginn, Samantha L, Lek, Monkol, North, Kathryn N, Alexander, Ian E, Little, David G, Schindeler, Aaron

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Human Induced Pluripotent Stem Cells Derived Under Feeder-Free Conditions Display Unique Cell Cycle and DNA Replication Gene Profiles od Chung, Henry C.Y., Lin, Ruby C.Y., Logan, Grant J., Alexander, Ian E., Sachdev, Perminder S., Sidhu, Kuldip S.

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Induction and Prevention of Severe Hyperammonemia in the spf(ash) Mouse Model of Ornithine Transcarbamylase Deficiency Using shRNA and rAAV-mediated Gene Delivery od Cunningham, Sharon C, Kok, Cindy Y, Dane, Allison P, Carpenter, Kevin, Kizana, Eddy, Kuchel, Philip W, Alexander, Ian E

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A bioinformatic pipeline for simulating viral integration data od Scott, Suzanne, Grigson, Susanna, Hartkopf, Felix, Hallwirth, Claus V., Alexander, Ian E., Bauer, Denis C., Wilson, Laurence O.W.

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HeLa cells cocultured with peripheral blood lymphocytes acquire an immuno-inhibitory phenotype through up-regulation of indoleamine 2,3-dioxygenase activity od Logan, Grant J, Smyth, Christine M F, Earl, John W, Zaikina, Irina, Rowe, Peter B, Smythe, Jason A, Alexander, Ian E

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Impact of next-generation sequencing error on analysis of barcoded plasmid libraries of known complexity and sequence od Deakin, Claire T., Deakin, Jeffrey J., Ginn, Samantha L., Young, Paul, Humphreys, David, Suter, Catherine M., Alexander, Ian E., Hallwirth, Claus V.

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Liver‐Targeted Angiotensin Converting Enzyme 2 Therapy Inhibits Chronic Biliary Fibrosis in Multiple Drug‐Resistant Gene 2‐Knockout Mice od Rajapaksha, Indu G., Gunarathne, Lakmie S., Asadi, Khashayar, Cunningham, Sharon C., Sharland, Alexandra, Alexander, Ian E., Angus, Peter W., Herath, Chandana B.

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Performance of Cardiotropic rAAV Vectors Is Dependent on Production Method od Rao, Renuka, Farraha, Melad, Logan, Grant J., Igoor, Sindhu, Kok, Cindy Y., Chong, James J. H., Alexander, Ian E., Kizana, Eddy

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Mitochondrial Respiratory Chain Hepatopathies: Role of Liver Transplantation. A Case Series of Five Patients od De Greef, Elisabeth, Christodoulou, John, Alexander, Ian E, Shun, Albert, O’Loughlin, Edward V, Thorburn, David R, Jermyn, Vicki, Stormon, Michael O

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Angiotensin Converting Enzyme‐2 Therapy Improves Liver Fibrosis and Glycemic Control in Diabetic Mice With Fatty Liver od Rajapaksha, Indu G., Gunarathne, Lakmie S., Asadi, Khashayar, Laybutt, Ross, Andrikopoulous, Sof, Alexander, Ian E., Watt, Mathew J., Angus, Peter W., Herath, Chandana B.

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Adeno-associated Virus-mediated Rescue of Neonatal Lethality in Argininosuccinate Synthetase-deficient Mice od Kok, Cindy Y, Cunningham, Sharon C, Carpenter, Kevin H, Dane, Allison P, Siew, Susan M, Logan, Grant J, Kuchel, Philip W, Alexander, Ian E

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Use of a Hybrid Adeno-Associated Viral Vector Transposon System to Deliver the Insulin Gene to Diabetic NOD Mice od La, Que T., Ren, Binhai, Logan, Grant J., Cunningham, Sharon C., Khandekar, Neeta, Nassif, Najah T., O’Brien, Bronwyn A., Alexander, Ian E., Simpson, Ann M.

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Selection and evaluation of clinically relevant AAV variants in a xenograft liver model od Lisowski, Leszek, Dane, Allison P., Chu, Kirk, Zhang, Yue, Cunningham, Sharon C., Wilson, Elizabeth M., Nygaard, Sean, Grompe, Markus, Alexander, Ian E., Kay, Mark A.

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