检索结果 - Aleksandra Markovets

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  1. 1
    Exon 16–Skipping HER2 as a Novel Mechanism of Osimertinib Resistance in EGFR L858R/T790M–Positive Non–Small Cell Lung Cancer

    Exon 16–Skipping HER2 as a Novel Mechanism of Osimertinib Resistance in EGFR L858R/T790M–Positive Non–Small Cell Lung Cancer 由 Chia‐Chi Hsu, Bin-Chi Liao, Wei‐Yu Liao, Aleksandra Markovets, Daniel Stetson, Kenneth S. Thress, James Chih‐Hsin Yang

    出版 2019
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  2. 2
    An artificial intelligence-based model for prediction of clonal hematopoiesis variants in cell-free DNA samples

    An artificial intelligence-based model for prediction of clonal hematopoiesis variants in cell-free DNA samples 由 Gustavo Arango-Argoty, Marzieh Haghighi, Gerald J. Sun, Elizabeth Choe, Aleksandra Markovets, J. Carl Barrett, Zhongwu Lai, Etai Jacob

    出版 2025
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  3. 3
    VarDict: a novel and versatile variant caller for next-generation sequencing in cancer research

    VarDict: a novel and versatile variant caller for next-generation sequencing in cancer research 由 Zhongwu Lai, Aleksandra Markovets, Miika Ahdesmäki, Brad Chapman, Oliver Hofmann, Robert McEwen, Justin Johnson, Brian Dougherty, J. Carl Barrett, Jonathan R. Dry

    出版 2016
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  4. 4
    Programmed Cell Death Ligand 1 Expression in Untreated EGFR Mutated Advanced NSCLC and Response to Osimertinib Versus Comparator in FLAURA

    Programmed Cell Death Ligand 1 Expression in Untreated EGFR Mutated Advanced NSCLC and Response to Osimertinib Versus Comparator in FLAURA 由 Helen Brown, Johan Vansteenkiste, Kazuhiko Nakagawa, Manuel Cobo, Thomas John, Craig Barker, Alexander Kohlmann, Alexander Todd, Matilde Saggese, Juliann Chmielecki, Aleksandra Markovets, Marietta Scott, Suresh S. Ramalingam

    出版 2019
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  5. 5
    Clinical impact of subclonal EGFR T790M mutations in advanced-stage EGFR-mutant non-small-cell lung cancers

    Clinical impact of subclonal EGFR T790M mutations in advanced-stage EGFR-mutant non-small-cell lung cancers 由 Tereza Vaclová, Ursula Grazini, Lewis S. C. Ward, Daniel O’Neill, Aleksandra Markovets, Xiangning Huang, Juliann Chmielecki, Ryan J. Hartmaier, Kenneth S. Thress, Paul D. Smith, J. Carl Barrett, Julian Downward, Elza C. de Bruin

    出版 2021
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  6. 6
    Mechanisms of acquired resistance to first-line osimertinib: Preliminary data from the phase III FLAURA study

    Mechanisms of acquired resistance to first-line osimertinib: Preliminary data from the phase III FLAURA study 由 Suresh S. Ramalingam, Yi Cheng, C. Zhou, Y. Ohe, Fumio Imamura, Byoung Chul Cho, Meng‐Chih Lin, Margarita Majem, Riyaz Shah, Yuri Rukazenkov, A. Todd, Aleksandra Markovets, J. Carl Barrett, Juliann Chmielecki, Jhanelle E. Gray

    出版 2018
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  7. 7
    Candidate mechanisms of acquired resistance to first-line osimertinib in EGFR-mutated advanced non-small cell lung cancer

    Candidate mechanisms of acquired resistance to first-line osimertinib in EGFR-mutated advanced non-small cell lung cancer 由 Juliann Chmielecki, Jhanelle E. Gray, Ying Cheng, Yuichiro Ohe, Fumio Imamura, Byoung Chul Cho, Meng‐Chih Lin, Margarita Majem, Riyaz Shah, Yuri Rukazenkov, Alexander Todd, Aleksandra Markovets, J. Carl Barrett, Ryan J. Hartmaier, Suresh S. Ramalingam

    出版 2023
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  8. 8
    Acquired EGFR C797S mutation mediates resistance to AZD9291 in non–small cell lung cancer harboring EGFR T790M

    Acquired EGFR C797S mutation mediates resistance to AZD9291 in non–small cell lung cancer harboring EGFR T790M 由 Kenneth S. Thress, Cloud P. Paweletz, Enriqueta Felip, Byoung Chul Cho, Daniel Stetson, Brian Dougherty, Zhongwu Lai, Aleksandra Markovets, Ana Vivancos, Yanan Kuang, Dalia Ercan, Sarah E Matthews, Mireille Cantarini, J. Carl Barrett, Pasi A. Jänne, Geoffrey R. Oxnard

    出版 2015
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  9. 9
    Targeting melanoma’s MCL1 bias unleashes the apoptotic potential of BRAF and ERK1/2 pathway inhibitors

    Targeting melanoma’s MCL1 bias unleashes the apoptotic potential of BRAF and ERK1/2 pathway inhibitors 由 Matthew J. Sale, Emma Minihane, Noel R. Monks, Rebecca Gilley, Frances M. Richards, Kevin Schifferli, Courtney L. Andersen, Emma Jane Davies, Mario Aladren Vicente, Eiko Ozono, Aleksandra Markovets, Jonathan R. Dry, Lisa Drew, Vikki Flemington, Theresa A. Proia, Duncan I. Jodrell, Paul D. Smith, Simon J. Cook

    出版 2019
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  10. 10
    Epidermal growth factor receptor mutation analysis in tissue and plasma from the AURA3 trial: Osimertinib versus platinum‐pemetrexed for T790M mutation‐positive advanced non–small cell lung cancer

    Epidermal growth factor receptor mutation analysis in tissue and plasma from the AURA3 trial: Osimertinib versus platinum‐pemetrexed for T790M mutation‐positive advanced non–small... 由 Vassiliki A. Papadimitrakopoulou, Ji‐Youn Han, Myung‐Ju Ahn, Suresh S. Ramalingam, Angelo Delmonte, Te‐Chun Hsia, Janessa Laskin, Sang‐We Kim, Yong He, Chun‐Ming Tsai, Toyoaki Hida, Makoto Maemondo, Terufumi Kato, Suzanne Jenkins, S. Patel, Xiangning Huang, Gianluca Laus, Aleksandra Markovets, Kenneth S. Thress, Yi‐Long Wu, Tony Mok

    出版 2019
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  11. 11
    Molecular residual disease analysis of adjuvant osimertinib in resected EGFR-mutated stage IB–IIIA non-small-cell lung cancer

    Molecular residual disease analysis of adjuvant osimertinib in resected EGFR-mutated stage IB–IIIA non-small-cell lung cancer 由 Roy S. Herbst, Thomas John, Christian Grohé, Jonathan W. Goldman, Terufumi Kato, К. К. Лактионов, Laura Bonanno, Marcello Tiseo, Margarita Majem, Manuel Dómine, Myung‐Ju Ahn, Dariusz M. Kowalski, M. Pérol, Virote Sriuranpong, Mustafa Özgüroğlu, Preetida J. Bhetariya, Aleksandra Markovets, Yuri Rukazenkov, Caitlin Muldoon, Jacqulyne Robichaux, Ryan J. Hartmaier, Masahiro Tsuboi, Yi‐Long Wu

    出版 2025
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  12. 12
    Osimertinib + Savolitinib to Overcome Acquired MET-Mediated Resistance in Epidermal Growth Factor Receptor–Mutated, <i>MET</i>-Amplified Non–Small Cell Lung Cancer: TATTON

    Osimertinib + Savolitinib to Overcome Acquired MET-Mediated Resistance in Epidermal Growth Factor Receptor–Mutated, <i>MET</i>-Amplified Non–Small Cell Lung Cancer: TATTON 由 Ryan J. Hartmaier, Aleksandra Markovets, Myung‐Ju Ahn, Lecia V. Sequist, Ji‐Youn Han, Byoung Chul Cho, Helena A. Yu, Sang‐We Kim, James Chih‐Hsin Yang, Jong Seok Lee, Wu‐Chou Su, Dariusz M. Kowalski, С. В. Орлов, Song Ren, Paul Frewer, Xiaoling Ou, Darren A.E. Cross, Nisha Kurian, Mireille Cantarini, Pasi A. Jänne

    出版 2022
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  13. 13
    Early Clearance of Plasma <i>Epidermal Growth Factor Receptor</i> Mutations as a Predictor of Outcome on Osimertinib in Advanced Non–Small Cell Lung Cancer; Exploratory Analysis from AURA3 and FLAURA

    Early Clearance of Plasma <i>Epidermal Growth Factor Receptor</i> Mutations as a Predictor of Outcome on Osimertinib in Advanced Non–Small Cell Lung Cancer; Exploratory Analysis fr... 由 Jhanelle E. Gray, Myung‐Ju Ahn, Geoffrey R. Oxnard, Frances A. Shepherd, Fumio Imamura, Ying Cheng, Isamu Okamoto, Byoung Chul Cho, Meng‐Chih Lin, Yi‐Long Wu, Margarita Majem, Oliver Gautschi, Michael Boyer, Krishna C. Bulusu, Aleksandra Markovets, J. Carl Barrett, Rachel Hodge, Astrid McKeown, Ryan J. Hartmaier, Juliann Chmielecki, Vassiliki A. Papadimitrakopoulou, Suresh S. Ramalingam

    出版 2023
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  14. 14
    Acquired Resistance to the Mutant-Selective EGFR Inhibitor AZD9291 Is Associated with Increased Dependence on RAS Signaling in Preclinical Models

    Acquired Resistance to the Mutant-Selective EGFR Inhibitor AZD9291 Is Associated with Increased Dependence on RAS Signaling in Preclinical Models 由 Catherine A. Eberlein, Daniel Stetson, Aleksandra Markovets, Katherine Al-Kadhimi, Zhongwu Lai, Paul R. Fisher, Catherine B. Meador, Paula J. Spitzler, Eiki Ichihara, Sarah J. Ross, Miika Ahdesmäki, Ambar Ahmed, Laura E. Ratcliffe, Elizabeth L. Christey O'Brien, Claire H. Barnes, H. Shelton Brown, Paul D. Smith, Jonathan R. Dry, Garry Beran, Kenneth S. Thress, Brian Dougherty, William Pao, Darren A.E. Cross

    出版 2015
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  15. 15
    Mixed responses to targeted therapy driven by chromosomal instability through p53 dysfunction and genome doubling

    Mixed responses to targeted therapy driven by chromosomal instability through p53 dysfunction and genome doubling 由 Sebastijan Hobor, Maise Al Bakir, Crispin T. Hiley, Marcin Skrzypski, Alexander M. Frankell, Björn Bakker, Anne Thomas, Aleksandra Markovets, Jonathan R. Dry, Andy Brown, Jasper van der Aart, Hilda van den Bos, Diana C.J. Spierings, Dahmane Oukrif, Marco Novelli, Turja Chakrabarti, Adam Rabinowitz, Laila Ait Hassou, Saskia Litière, D. Lucas Kerr, Lisa Tan, Gavin Kelly, David A. Moore, Matthew J. Renshaw, Subramanian Venkatesan, William Hill, Ariana Huebner, Carlos Martínez‐Ruiz, James R. Black, Wei Wu, Mihaela Angelova, Nicholas McGranahan, Julian Downward, Juliann Chmielecki, Carl Barrett, Kevin Litchfield, Su Kit Chew, Collin M. Blakely, Elza C. de Bruin, Floris Foijer, Karen H. Vousden, Trever G. Bivona, J.F. Lester, Amrita Bajaj, Apostolos Nakas, Azmina Sodha-Ramdeen, Mohamad Tufail, Molly Scotland, Rebecca Boyles, Sridhar Rathinam, Claire Wilson, Domenic Marrone, Sean Dulloo, Dean A. Fennell, Gurdeep Matharu, Jacqui Shaw, Ekaterini Boleti, Heather Cheyne, Mohammed S. Khalil, Shirley Richardson, Tracey Cruickshank, Gillian Price, Keith M. Kerr, Sarah Benafif, Jack French, Kayleigh Gilbert, Babu Naidu, Akshay J. Patel, Aya Osman, Carol Enstone, Gerald Langman, Helen Shackleford, Madava Djearaman, Salma Kadiri, Gary Middleton, Angela Leek, Jack Davies Hodgkinson, Nikki Totton, Ángeles Montero, Elaine Smith, Eustace Fontaine, Felice Granato, António Paiva‐Correia, Juliette Novasio, Kendadai Rammohan, Leena Dennis Joseph, Paul Bishop, Rajesh Shah, Stuart Moss, Vijay V. Joshi, Philip Crosbie, Kate Brown, Mathew Carter, Anshuman Chaturvedi, Pedro Oliveira, Colin R. Lindsay, Fiona Blackhall, Matthew Krebs, Yvonne Summers, Alexandra Clipson

    出版 2024
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