Hakutulokset - Aleksandar Z. Obradovic

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  1. 1
    Evaluating factors impacting early career physician-scientists’ decisions to continue research careers in the United States of America

    Evaluating factors impacting early career physician-scientists’ decisions to continue research careers in the United States of America Tekijä Kassem Farhat, Aleksandar Z. Obradovic, Aisha L. Siebert, Han Naung Tun, Evan Noch, Jennifer M. Kwan

    Julkaistu 2025
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  2. 2
    Immunogenicity of prostate cancer is augmented by BET bromodomain inhibition

    Immunogenicity of prostate cancer is augmented by BET bromodomain inhibition Tekijä Wendy Mao, Ali Ghasemzadeh, Zachary T. Freeman, Aleksandar Z. Obradovic, Matthew G. Chaimowitz, Thomas R. Nirschl, Emily McKiernan, Srinivasan Yegnasubramanian, Charles G. Drake

    Julkaistu 2019
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  3. 3
    Siplizumab selectively depletes effector memory T cells and promotes a relative expansion of alloreactive regulatory T cells in vitro

    Siplizumab selectively depletes effector memory T cells and promotes a relative expansion of alloreactive regulatory T cells in vitro Tekijä Manuel Alfredo Podestà, Christian Binder, Felix Sellberg, Susan DeWolf, Brittany Shonts, Siu‐Hong Ho, Aleksandar Z. Obradovic, Elizabeth Waffarn, Nichole Danzl, David Berglund, Megan Sykes

    Julkaistu 2019
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  4. 4
    Quantifying size and diversity of the human T cell alloresponse

    Quantifying size and diversity of the human T cell alloresponse Tekijä Susan DeWolf, Boris Grinshpun, Thomas Savage, Sai Ping Lau, Aleksandar Z. Obradovic, Brittany Shonts, Suxiao Yang, Heather Morris, Julien Zuber, Robert Winchester, Megan Sykes, Yufeng Shen

    Julkaistu 2018
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  5. 5
    Early expansion of donor-specific Tregs in tolerant kidney transplant recipients

    Early expansion of donor-specific Tregs in tolerant kidney transplant recipients Tekijä Thomas Savage, Brittany Shonts, Aleksandar Z. Obradovic, Susan DeWolf, Sai Ping Lau, Julien Zuber, Michael T. Simpson, Erik Berglund, Jianing Fu, Suxiao Yang, Siu‐Hong Ho, Qizhi Tang, Laurence A. Turka, Yufeng Shen, Megan Sykes

    Julkaistu 2018
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  6. 6
    Cross-reactive public TCR sequences undergo positive selection in the human thymic repertoire

    Cross-reactive public TCR sequences undergo positive selection in the human thymic repertoire Tekijä Mohsen Khosravi‐Maharlooei, Aleksandar Z. Obradovic, A. Misra, Keshav Motwani, Markus A. Hölzl, Howard R. Seay, Susan DeWolf, Grace Nauman, Nichole Danzl, Haowei Li, Siu‐Hong Ho, Robert Winchester, Yufeng Shen, Todd M. Brusko, Megan Sykes

    Julkaistu 2019
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  7. 7
    Blocking IL1 Beta Promotes Tumor Regression and Remodeling of the Myeloid Compartment in a Renal Cell Carcinoma Model: Multidimensional Analyses

    Blocking IL1 Beta Promotes Tumor Regression and Remodeling of the Myeloid Compartment in a Renal Cell Carcinoma Model: Multidimensional Analyses Tekijä David H. Aggen, Casey R. Ager, Aleksandar Z. Obradovic, Nivedita Chowdhury, Ali Ghasemzadeh, Wendy Mao, Matthew G. Chaimowitz, Zoila A. Lopez‐Bujanda, Catherine S. Spina, Jessica E. Hawley, Matthew C. Dallos, Cheng Zhang, Vinson Wang, Hu Li, Xinzheng V. Guo, Charles G. Drake

    Julkaistu 2020
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  8. 8
    Immunostimulatory Cancer-Associated Fibroblast Subpopulations Can Predict Immunotherapy Response in Head and Neck Cancer

    Immunostimulatory Cancer-Associated Fibroblast Subpopulations Can Predict Immunotherapy Response in Head and Neck Cancer Tekijä Aleksandar Z. Obradovic, Diana Graves, Michael Korrer, Yu Wang, Sohini Roy, Abdullah Naveed, Yaomin Xu, Adam Luginbuhl, Joseph Curry, Michael K. Gibson, Kamran Idrees, Paula J. Hurley, Peng Jiang, X. Shirley Liu, Ravindra Uppaluri, Charles G. Drake, Andrea Califano, Young J. Kim

    Julkaistu 2022
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  9. 9
    Bidirectional intragraft alloreactivity drives the repopulation of human intestinal allografts and correlates with clinical outcome

    Bidirectional intragraft alloreactivity drives the repopulation of human intestinal allografts and correlates with clinical outcome Tekijä Julien Zuber, Brittany Shonts, Sai Ping Lau, Aleksandar Z. Obradovic, Jianing Fu, Suxiao Yang, Marion Lambert, Shana M. Coley, Joshua Weiner, Joseph Thome, Susan DeWolf, Donna L. Färber, Yufeng Shen, Sophie Caillat‐Zucman, Govind Bhagat, Adam Griesemer, Mercedes Martínez, Tomoaki Kato, Megan Sykes

    Julkaistu 2016
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  10. 10
    Single-cell protein activity analysis identifies recurrence-associated renal tumor macrophages

    Single-cell protein activity analysis identifies recurrence-associated renal tumor macrophages Tekijä Aleksandar Z. Obradovic, Nivedita Chowdhury, Scott M. Haake, Casey R. Ager, Vinson Wang, Lukas Vlahos, Xinzheng V. Guo, David H. Aggen, W. Kimryn Rathmell, Eric Jonasch, Joyce E. Johnson, Marc Roth, Kathryn E. Beckermann, Brian I. Rini, James M. McKiernan, Andrea Califano, Charles G. Drake

    Julkaistu 2021
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  11. 11
    Origin of Enriched Regulatory T Cells in Patients Receiving Combined Kidney–Bone Marrow Transplantation to Induce Transplantation Tolerance

    Origin of Enriched Regulatory T Cells in Patients Receiving Combined Kidney–Bone Marrow Transplantation to Induce Transplantation Tolerance Tekijä Ben Sprangers, Susan DeWolf, Thomas Savage, T. Morokata, Aleksandar Z. Obradovic, Samuel A. LoCascio, Brittany Shonts, Julien Zuber, Sai Ping Lau, Ravi R. Shah, Heather Morris, Valeria Steshenko, E. Zorn, F I Preffer, Sven Olek, David Dombkowski, Laurence A. Turka, Richard A. Colvin, Robert Winchester, Tatsuo Kawai, M. Sykes

    Julkaistu 2017
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  12. 12
    Human Intestinal Allografts Contain Functional Hematopoietic Stem and Progenitor Cells that Are Maintained by a Circulating Pool

    Human Intestinal Allografts Contain Functional Hematopoietic Stem and Progenitor Cells that Are Maintained by a Circulating Pool Tekijä Jianing Fu, Julien Zuber, Mercedes Martínez, Brittany Shonts, Aleksandar Z. Obradovic, Hui Wang, Sai Ping Lau, Amy Xia, Elizabeth Waffarn, Kristjana Frangaj, Thomas Savage, Michael T. Simpson, Suxiao Yang, Xinzheng V. Guo, Michelle Miron, Takashi Senda, Kortney Rogers, Adeeb Rahman, Siu‐Hong Ho, Yufeng Shen, Adam Griesemer, Donna L. Färber, Tomoaki Kato, Megan Sykes

    Julkaistu 2018
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  13. 13
    T-Cell Infiltration and Adaptive Treg Resistance in Response to Androgen Deprivation With or Without Vaccination in Localized Prostate Cancer

    T-Cell Infiltration and Adaptive Treg Resistance in Response to Androgen Deprivation With or Without Vaccination in Localized Prostate Cancer Tekijä Aleksandar Z. Obradovic, Matthew C. Dallos, Marianna Zahurak, Alan W. Partin, Edward M. Schaeffer, Ashley E. Ross, Mohamad E. Allaf, Thomas R. Nirschl, David Liu, Carolyn G. Chapman, Tanya O’Neal, Haiyi Cao, Jennifer N. Durham, Güneş Güner, Javier Baena-Del Valle, Onur Ertunç, Angelo M. De Marzo, Emmanuel S. Antonarakis, Charles G. Drake

    Julkaistu 2020
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  14. 14
    Castration-mediated IL-8 promotes myeloid infiltration and prostate cancer progression

    Castration-mediated IL-8 promotes myeloid infiltration and prostate cancer progression Tekijä Zoila A. Lopez‐Bujanda, Michael C. Haffner, Matthew G. Chaimowitz, Nivedita Chowdhury, Nicholas Venturini, Radhika A. Patel, Aleksandar Z. Obradovic, C. Hansen, J. Jackow, Janielle P. Maynard, Karen S. Sfanos, Cory Abate‐Shen, Charles J. Bieberich, Paula J. Hurley, Mark Selby, Alan J. Korman, Angela M. Christiano, Angelo M. De Marzo, Charles G. Drake

    Julkaistu 2021
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  15. 15
    Lymphohematopoietic graft-versus-host responses promote mixed chimerism in patients receiving intestinal transplantation

    Lymphohematopoietic graft-versus-host responses promote mixed chimerism in patients receiving intestinal transplantation Tekijä Jianing Fu, Julien Zuber, Brittany Shonts, Aleksandar Z. Obradovic, Zicheng Wang, Kristjana Frangaj, Wenzhao Meng, Aaron M. Rosenfeld, Elizabeth Waffarn, Peter Liou, Sai Ping Lau, Thomas Savage, Suxiao Yang, Kortney Rogers, Nichole Danzl, Shilpa Ravella, Prakash Satwani, Alina C. Iuga, Siu‐Hong Ho, Adam Griesemer, Yufeng Shen, Eline T. Luning Prak, Mercedes Martínez, Tomoaki Kato, Megan Sykes

    Julkaistu 2021
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  16. 16
    Systematic elucidation and pharmacological targeting of tumor-infiltrating regulatory T cell master regulators

    Systematic elucidation and pharmacological targeting of tumor-infiltrating regulatory T cell master regulators Tekijä Aleksandar Z. Obradovic, Casey R. Ager, Mikko Turunen, Thomas R. Nirschl, Mohsen Khosravi‐Maharlooei, Alina C. Iuga, Christopher M. Jackson, Srinivasan Yegnasubramanian, Lorenzo Tomassoni, Ester Calvo Fernández, Patrick McCann, Meri Rogava, Angelo M. De Marzo, Christina M. Kochel, Mohamad E. Allaf, Trinity J. Bivalacqua, Michael Lim, Ronald Realubit, Charles Karan, Charles G. Drake, Andrea Califano

    Julkaistu 2023
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  17. 17
    Anti-PD-1 immunotherapy with androgen deprivation therapy induces robust immune infiltration in metastatic castration-sensitive prostate cancer

    Anti-PD-1 immunotherapy with androgen deprivation therapy induces robust immune infiltration in metastatic castration-sensitive prostate cancer Tekijä Jessica E. Hawley, Aleksandar Z. Obradovic, Matthew C. Dallos, Emerson A. Lim, Karie Runcie, Casey R. Ager, James M. McKiernan, Christopher B. Anderson, G. Joel DeCastro, Joshua Weintraub, Renu K. Virk, Israel Lowy, Jianhua Hu, Matthew G. Chaimowitz, Xinzheng V. Guo, Ya Zhang, Michael C. Haffner, Jeremy Worley, Mark N. Stein, Andrea Califano, Charles G. Drake

    Julkaistu 2023
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  18. 18
    B7-H3 as a Therapeutic Target in Advanced Prostate Cancer

    B7-H3 as a Therapeutic Target in Advanced Prostate Cancer Tekijä Christina Guo, Ines Figueiredo, Bora Gürel, Antje Neeb, George Seed, Mateus Crespo, Suzanne Carreira, Jan Rekowski, Lorenzo Buroni, Jon Welti, Denisa Bogdan, Lewis Gallagher, Adam Sharp, Maria D. Fenor de la Maza, Pasquale Rescigno, Daniel Westaby, Khobe Chandran, Ruth Riisnaes, Ana Ferreira, Susana Miranda, Bianca Calì, Andrea Alimonti, Silvia Bressan, Alana H.T. Nguyen, Michael M. Shen, Jessica E. Hawley, Aleksandar Z. Obradovic, Charles G. Drake, Cláudia Bertan, Chloe Baker, Nina Tunariu, Wei Yuan, Johann S. de Bono

    Julkaistu 2022
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  19. 19
    Single-cell analysis of treatment-resistant prostate cancer: Implications of cell state changes for cell surface antigen–targeted therapies

    Single-cell analysis of treatment-resistant prostate cancer: Implications of cell state changes for cell surface antigen–targeted therapies Tekijä Samir Zaidi, Jooyoung Park, Joseph M. Chan, Martine P. Roudier, Jimmy L. Zhao, Anuradha Gopalan, Kristine M. Wadosky, Radhika A. Patel, Erolcan Sayar, Wouter R. Karthaus, D. Henry Kates, Ojasvi Chaudhary, Tianhao Xu, Ignas Masilionis, Linas Mažutis, Ronan Chaligné, Aleksandar Z. Obradovic, Irina Linkov, Afşar Barlas, Achim A. Jungbluth, Natasha Rekhtman, Joachim Silber, Katia Manova‐Todorova, Philip A. Watson, Lawrence D. True, Colm Morrissey, Howard I. Scher, Dana E. Rathkopf, Michael J. Morris, David W. Goodrich, Jungmin Choi, Peter S. Nelson, Michael C. Haffner, Charles L. Sawyers

    Julkaistu 2024
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