Søgeresultater - Alba Luengo

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  1. 1
    Understanding the complex-I-ty of metformin action: limiting mitochondrial respiration to improve cancer therapy

    Understanding the complex-I-ty of metformin action: limiting mitochondrial respiration to improve cancer therapy af Alba Luengo, Lucas B. Sullivan, Matthew G. Vander Heiden

    Udgivet 2014
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  2. 2
    Targeting Metabolism for Cancer Therapy

    Targeting Metabolism for Cancer Therapy af Alba Luengo, Dan Y. Gui, Matthew G. Vander Heiden

    Udgivet 2017
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  3. 3
    Outpatient Submaxillectomy Using Active Drains. Safety of the Procedure and Patient Satisfaction

    Outpatient Submaxillectomy Using Active Drains. Safety of the Procedure and Patient Satisfaction af García-de Marcos, José-Antonio, del Amo-Fernández de Velasco, Alvaro, Fernández Alba-Luengo, Javier

    Udgivet 2021
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  4. 4
    Germline loss of PKM2 promotes metabolic distress and hepatocellular carcinoma

    Germline loss of PKM2 promotes metabolic distress and hepatocellular carcinoma af Talya L. Dayton, Vasilena Gocheva, Kathryn Miller, William J. Israelsen, Arjun Bhutkar, Clary B. Clish, Shawn M. Davidson, Alba Luengo, Roderick T. Bronson, Tyler Jacks, Matthew G. Vander Heiden

    Udgivet 2016
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  5. 5
    Environment Dictates Dependence on Mitochondrial Complex I for NAD+ and Aspartate Production and Determines Cancer Cell Sensitivity to Metformin

    Environment Dictates Dependence on Mitochondrial Complex I for NAD+ and Aspartate Production and Determines Cancer Cell Sensitivity to Metformin af Dan Y. Gui, Lucas B. Sullivan, Alba Luengo, Aaron M. Hosios, Lauren N. Bush, Nadege Gitego, Shawn M. Davidson, Elizaveta Freinkman, Craig J. Thomas, Matthew G. Vander Heiden

    Udgivet 2016
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  6. 6
    REV1 inhibitor JH-RE-06 enhances tumor cell response to chemotherapy by triggering senescence hallmarks

    REV1 inhibitor JH-RE-06 enhances tumor cell response to chemotherapy by triggering senescence hallmarks af Nimrat Chatterjee, Matthew A. Whitman, Cynthia Harris, Sophia M. Min, Oliver Jonas, Evan C. Lien, Alba Luengo, Matthew G. Vander Heiden, Jiyong Hong, Pei Zhou, Michael T. Hemann, Graham C. Walker

    Udgivet 2020
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  7. 7
    Aspartate is an endogenous metabolic limitation for tumour growth

    Aspartate is an endogenous metabolic limitation for tumour growth af Lucas B. Sullivan, Alba Luengo, Laura V. Danai, Lauren N. Bush, Frances F. Diehl, Aaron M. Hosios, Allison N. Lau, Sarah Elmiligy, Scott Malstrom, Caroline A. Lewis, Matthew G. Vander Heiden

    Udgivet 2018
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  8. 8
    Deoxycytidine Release from Pancreatic Stellate Cells Promotes Gemcitabine Resistance

    Deoxycytidine Release from Pancreatic Stellate Cells Promotes Gemcitabine Resistance af Simona Dalin, Mark R. Sullivan, Allison N. Lau, Beatrice Grauman-Boss, Helen S. Mueller, Emanuel Kreidl, Silvia Fenoglio, Alba Luengo, Jacqueline A. Lees, Matthew G. Vander Heiden, Douglas A. Lauffenburger, Michael T. Hemann

    Udgivet 2019
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  9. 9
    Increased demand for NAD+ relative to ATP drives aerobic glycolysis

    Increased demand for NAD+ relative to ATP drives aerobic glycolysis af Alba Luengo, Zhaoqi Li, Dan Y. Gui, Lucas B. Sullivan, Maria Zagorulya, T. Brian, Raphaël Ferreira, Adi Naamati, Ahmed Ali, Caroline A. Lewis, Craig J. Thomas, Stefani Spranger, Nicholas J. Matheson, Matthew G. Vander Heiden

    Udgivet 2020
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  10. 10
    Reactive metabolite production is a targetable liability of glycolytic metabolism in lung cancer

    Reactive metabolite production is a targetable liability of glycolytic metabolism in lung cancer af Alba Luengo, Keene L. Abbott, Shawn M. Davidson, Aaron M. Hosios, Brandon Faubert, Sze Ham Chan, Elizaveta Freinkman, Lauren G. Zacharias, Thomas P. Mathews, Clary B. Clish, Ralph J. DeBerardinis, Caroline A. Lewis, Matthew G. Vander Heiden

    Udgivet 2019
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  11. 11
    Cytosolic Aspartate Availability Determines Cell Survival When Glutamine Is Limiting

    Cytosolic Aspartate Availability Determines Cell Survival When Glutamine Is Limiting af H. Furkan Alkan, Katharina E. Walter, Alba Luengo, Corina T. Madreiter‐Sokolowski, Sarah Stryeck, Allison N. Lau, Wael Al Zoughbi, Caroline A. Lewis, Craig J. Thomas, Gerald Höefler, Wolfgang F. Graier, Tobias Madl, Matthew G. Vander Heiden, Juliane Gertrude Bogner‐Strauß

    Udgivet 2018
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  12. 12
    Environment Impacts the Metabolic Dependencies of Ras-Driven Non-Small Cell Lung Cancer

    Environment Impacts the Metabolic Dependencies of Ras-Driven Non-Small Cell Lung Cancer af Shawn M. Davidson, Thales Papagiannakopoulos, Benjamin A. Olenchock, Julia E. Heyman, Mark A. Keibler, Alba Luengo, Matthew R. Bauer, Abhishek Jha, James P. O’Brien, Kerry A. Pierce, Dan Y. Gui, Lucas B. Sullivan, Thomas M. Wasylenko, Lakshmipriya Subbaraj, Christopher R. Chin, Gregory Stephanopolous, Bryan T. Mott, Tyler Jacks, Clary B. Clish, Matthew G. Vander Heiden

    Udgivet 2016
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  13. 13
    Direct evidence for cancer-cell-autonomous extracellular protein catabolism in pancreatic tumors

    Direct evidence for cancer-cell-autonomous extracellular protein catabolism in pancreatic tumors af Shawn M. Davidson, Oliver Jonas, Mark A. Keibler, Han Wei Hou, Alba Luengo, Jared R. Mayers, Jeffrey Wyckoff, Amanda Del Rosario, Matthew A. Whitman, Christopher R. Chin, Kendall J. Condon, Alex Lammers, Katherine A. Kellersberger, Brian K Stall, Gregory Stephanopoulos, Dafna Bar‐Sagi, Jongyoon Han, Joshua D. Rabinowitz, Michael J. Cima, Róbert Langer, Matthew G. Vander Heiden

    Udgivet 2016
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  14. 14
    A PHGDH inhibitor reveals coordination of serine synthesis and one-carbon unit fate

    A PHGDH inhibitor reveals coordination of serine synthesis and one-carbon unit fate af Michael E. Pacold, Kyle R. Brimacombe, Sze Ham Chan, Jason M. Rohde, Caroline A. Lewis, Lotteke J. Y. M. Swier, Richard Possemato, Walter W. Chen, Lucas B. Sullivan, Brian P. Fiske, Steve K. Cho, Elizaveta Freinkman, Kıvanç Birsoy, Monther Abu-Remaileh, Yoav D. Shaul, Chieh Min Liu, Minerva Zhou, Min Jung Koh, Haeyoon Chung, Shawn M. Davidson, Alba Luengo, Amy Q. Wang, Xin Xu, Adam Yasgar, Li Liu, Ganesha Rai, Kenneth D. Westover, Matthew G. Vander Heiden, Min Shen, Nathanael S. Gray, Matthew B. Boxer, David M. Sabatini

    Udgivet 2016
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  15. 15
    Fatty acid synthesis is required for breast cancer brain metastasis

    Fatty acid synthesis is required for breast cancer brain metastasis af Gino B. Ferraro, Ahmed Ali, Alba Luengo, David P. Kodack, Amy Deik, Keene L. Abbott, Divya Bezwada, Landry Blanc, Brendan Prideaux, Xin Jin, Jessica M. Posada, Jiang Chen, Christopher R. Chin, Zohreh Amoozgar, Raphaël Ferreira, Ivy X. Chen, Kamila Naxerova, Christopher Ng, Anna M. Westermark, Mark Duquette, Sylvie Roberge, Neal I. Lindeman, Costas A. Lyssiotis, Jens Nielsen, David E. Housman, Dan G. Duda, Elena F. Brachtel, Todd R. Golub, Lewis C. Cantley, John M. Asara, Shawn M. Davidson, Dai Fukumura, Véronique Dartois, Clary B. Clish, Rakesh K. Jain, Matthew G. Vander Heiden

    Udgivet 2021
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  16. 16
    Limited Environmental Serine and Glycine Confer Brain Metastasis Sensitivity to PHGDH Inhibition

    Limited Environmental Serine and Glycine Confer Brain Metastasis Sensitivity to PHGDH Inhibition af Bryan Ngo, Eugenie Kim, Victoria Osorio-Vasquez, Sophia Doll, Sophia Bustraan, Roger J. Liang, Alba Luengo, Shawn M. Davidson, Ahmed Ali, Gino B. Ferraro, Grant M. Fischer, Roozbeh Eskandari, Diane S. Kang, Jing Ni, Ariana Plasger, Vinagolu K. Rajasekhar, Edward R. Kastenhuber, Sarah Bacha, Roshan K. Sriram, Benjamin D. Stein, Samuel F. Bakhoum, Matija Snuderl, Paolo Cotzia, John H. Healey, Nello Mainolfi, Vipin Suri, Adam Friedman, Mark Manfredi, David M. Sabatini, Drew R. Jones, Min Yu, Jean J. Zhao, Rakesh K. Jain, Kayvan R. Keshari, Michael A. Davies, Matthew G. Vander Heiden, Eva Hernando, Matthias Mann, Lewis C. Cantley, Michael E. Pacold

    Udgivet 2020
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