Resultados de búsqueda - Alan McIntyre

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  1. 1
    Metabolic and hypoxic adaptation to anti‐angiogenic therapy: a target for induced essentiality

    Metabolic and hypoxic adaptation to anti‐angiogenic therapy: a target for induced essentiality por Alan McIntyre, Adrian L. Harris

    Publicado 2015
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  2. 2
    Fatty Acid-binding Protein 4, a Point of Convergence for Angiogenic and Metabolic Signaling Pathways in Endothelial Cells

    Fatty Acid-binding Protein 4, a Point of Convergence for Angiogenic and Metabolic Signaling Pathways in Endothelial Cells por Ulrike Harjes, Esther Bridges, Alan McIntyre, Barbara A. Fielding, Adrian L. Harris

    Publicado 2014
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  3. 3
    Activating Mutations and/or Expression Levels of Tyrosine Kinase Receptors GRB7, RAS, and BRAF in Testicular Germ Cell Tumors

    Activating Mutations and/or Expression Levels of Tyrosine Kinase Receptors GRB7, RAS, and BRAF in Testicular Germ Cell Tumors por Alan McIntyre, Brenda Summersgill, Hayley E. Spendlove, Robert Huddart, Richard S. Houlston, Janet Shipley

    Publicado 2005
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  4. 4
    MicroRNA Post-transcriptional Regulation of the NLRP3 Inflammasome in Immunopathologies

    MicroRNA Post-transcriptional Regulation of the NLRP3 Inflammasome in Immunopathologies por Gülçin Tezcan, Ekaterina Martynova, Zarema E. Gilazieva, Alan McIntyre, Albert A. Rizvanov, Svetlana F. Khaiboullina

    Publicado 2019
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  5. 5
    Altered glutamine metabolism in breast cancer; subtype dependencies and alternative adaptations

    Altered glutamine metabolism in breast cancer; subtype dependencies and alternative adaptations por Rokaya El Ansari, Alan McIntyre, Madeleine L. Craze, Ian O. Ellis, Emad A. Rakha, Andrew R. Green

    Publicado 2017
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  6. 6
    Carbonic anhydrase IX induction defines a heterogeneous cancer cell response to hypoxia and mediates stem cell-like properties and sensitivity to HDAC inhibition

    Carbonic anhydrase IX induction defines a heterogeneous cancer cell response to hypoxia and mediates stem cell-like properties and sensitivity to HDAC inhibition por Ioanna Ledaki, Alan McIntyre, Simon Wigfield, Francesca M. Buffa, Simon J. McGowan, Dilair Baban, Jiliang Li, Adrian L. Harris

    Publicado 2015
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  7. 7
    Genomic alterations underlie a pan-cancer metabolic shift associated with tumour hypoxia

    Genomic alterations underlie a pan-cancer metabolic shift associated with tumour hypoxia por Syed Haider, Alan McIntyre, Ruud G.P.M. van Stiphout, Laura Winchester, Simon Wigfield, Adrian L. Harris, Francesca M. Buffa

    Publicado 2016
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  8. 8
    Is Telomere Length a Biomarker for Aging: Cross-Sectional Evidence from the West of Scotland?

    Is Telomere Length a Biomarker for Aging: Cross-Sectional Evidence from the West of Scotland? por Geoff Der, G. David Batty, Michaela Benzeval, Ian J. Deary, Michael J. Green, Liane M. McGlynn, Alan McIntyre, Tony Robertson, Paul G. Shiels

    Publicado 2012
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  9. 9
    PO-276 Histone acetylation readers BET in hypoxia adaptation in triple negative breast cancer (TNBC)

    PO-276 Histone acetylation readers BET in hypoxia adaptation in triple negative breast cancer (TNBC) por Leonardo Lisbôa da Motta, Ioanna Ledaki, Syed Haider, Marco Antônio De Bastiani, D Baban, Kendra Stefan, Fábio Klamt, David M. Heery, Adrian L. Harris, Alan McIntyre

    Publicado 2018
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  10. 10
    Therapeutic Potential of Pharmacological Targeting NLRP3 Inflammasome Complex in Cancer

    Therapeutic Potential of Pharmacological Targeting NLRP3 Inflammasome Complex in Cancer por Gülçin Tezcan, Ekaterina Garanina, Ali Al-Saadi, Zarema E. Gilazieva, Ekaterina V. Martinova, Maria Markelova, Svetlana S. Arkhipova, Shaimaa Hamza, Alan McIntyre, Albert A. Rizvanov, Svetlana F. Khaiboullina

    Publicado 2021
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  11. 11
    The pH low insertion peptide pHLIP Variant 3 as a novel marker of acidic malignant lesions

    The pH low insertion peptide pHLIP Variant 3 as a novel marker of acidic malignant lesions por Thomas T. Tapmeier, Anna Moshnikova, John S. Beech, Philip D. Allen, Paul Kinchesh, Sean Smart, Adrian L. Harris, Alan McIntyre, Donald M. Engelman, Oleg A. Andreev, Yana K. Reshetnyak, Ruth J. Muschel

    Publicado 2015
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  12. 12
    Glucose Utilization via Glycogen Phosphorylase Sustains Proliferation and Prevents Premature Senescence in Cancer Cells

    Glucose Utilization via Glycogen Phosphorylase Sustains Proliferation and Prevents Premature Senescence in Cancer Cells por Elena Favaro, Karim Bensaad, Mei Chong, Daniel A. Tennant, David Ferguson, Cameron Snell, Graham Steers, Helen Turley, Jiliang Li, Ulrich L. Günther, Francesca M. Buffa, Alan McIntyre, Adrian L. Harris

    Publicado 2012
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  13. 13
    Carbonic Anhydrase IX Promotes Tumor Growth and Necrosis<i>In Vivo</i>and Inhibition Enhances Anti-VEGF Therapy

    Carbonic Anhydrase IX Promotes Tumor Growth and Necrosis<i>In Vivo</i>and Inhibition Enhances Anti-VEGF Therapy por Alan McIntyre, Shalini Patiar, Simon Wigfield, Jiliang Li, Ioanna Ledaki, Helen Turley, Russell Leek, Cameron Snell, Kevin C. Gatter, William S. Sly, Richard D. Vaughan‐Jones, Pawel Swietach, Adrian L. Harris

    Publicado 2012
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  14. 14
    Disrupting Hypoxia-Induced Bicarbonate Transport Acidifies Tumor Cells and Suppresses Tumor Growth

    Disrupting Hypoxia-Induced Bicarbonate Transport Acidifies Tumor Cells and Suppresses Tumor Growth por Alan McIntyre, Alžbeta Hulı́ková, Ioanna Ledaki, Cameron Snell, Dean C. Singleton, Graham Steers, Peter Seden, Dylan T. Jones, Esther Bridges, Simon Wigfield, Jiliang Li, Angela J. Russell, Pawel Swietach, Adrian L. Harris

    Publicado 2016
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  15. 15
    Specific inhibition of carbonic anhydrase IX activity enhances the in vivo therapeutic effect of tumor irradiation

    Specific inhibition of carbonic anhydrase IX activity enhances the in vivo therapeutic effect of tumor irradiation por Ludwig J. Dubois, Sarah G.J.A. Peeters, Natasja G. Lieuwes, Nele Geusens, Anne Thiry, Simon Wigfield, Fabrizio Carta, Alan McIntyre, Andrea Scozzafava, Jean‐Michel Dogné, Claudiu T. Supuran, Adrian L. Harris, Bernard Masereel, Philippe Lambin

    Publicado 2011
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  16. 16
    The BET inhibitor JQ1 selectively impairs tumour response to hypoxia and downregulates CA9 and angiogenesis in triple negative breast cancer

    The BET inhibitor JQ1 selectively impairs tumour response to hypoxia and downregulates CA9 and angiogenesis in triple negative breast cancer por Leonardo Lisbôa da Motta, Ioanna Ledaki, Karin Purshouse, Syed Haider, Marco Antônio De Bastiani, D Baban, Matteo Morotti, Graham Steers, Simon Wigfield, Esther Bridges, JL Li, Stefan Knapp, Daniel Ebner, Fábio Klamt, Adrian L. Harris, Alan McIntyre

    Publicado 2016
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  17. 17
    Hypoxia-induced switch in SNAT2/SLC38A2 regulation generates endocrine resistance in breast cancer

    Hypoxia-induced switch in SNAT2/SLC38A2 regulation generates endocrine resistance in breast cancer por Matteo Morotti, Esther Bridges, Alessandro Valli, Hani Choudhry, Helen Sheldon, Simon Wigfield, Nicki Gray, Christos E. Zois, Fiona Grimm, Dylan T. Jones, Eugene Teoh, Wei‐Chen Cheng, Simon Lord, Dimitrios Anastasiou, Syed Haider, Alan McIntyre, Deborah C. I. Goberdhan, Francesca M. Buffa, Adrian L. Harris

    Publicado 2019
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  18. 18
    The Association of CCND1 Overexpression and Cisplatin Resistance in Testicular Germ Cell Tumors and Other Cancers

    The Association of CCND1 Overexpression and Cisplatin Resistance in Testicular Germ Cell Tumors and Other Cancers por Elodie Noël, Marc Yeste‐Velasco, Xueying Mao, Jackie Perry, Sakunthala C. Kudahetti, Ningfeng Fiona Li, Swee Y. Sharp, Tracy Chaplin, Liyan Xue, Alan McIntyre, Ling Shan, Thomas Powles, R.T.D. Oliver, Bryan D. Young, Janet Shipley, Daniel M. Berney, Simon P. Joel, Yong‐Jie Lu

    Publicado 2010
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  19. 19
    Drug-resilient Cancer Cell Phenotype Is Acquired via Polyploidization Associated with Early Stress Response Coupled to HIF2α Transcriptional Regulation

    Drug-resilient Cancer Cell Phenotype Is Acquired via Polyploidization Associated with Early Stress Response Coupled to HIF2α Transcriptional Regulation por Christopher Carroll, Auraya Manaprasertsak, Arthur Boffelli Castro, Hilda van den Bos, Diana C.J. Spierings, René Wardenaar, Anuraag Bukkuri, Niklas Engström, Etienne Baratchart, Minjun Yang, Andrea Biloglav, Charlie K. Cornwallis, Bertil Johansson, Catharina Hagerling, Marie Arsenian‐Henriksson, Kajsa Paulsson, Sarah R. Amend, Sofie Mohlin, Floris Foijer, Alan McIntyre, Kenneth J. Pienta, Emma U. Hammarlund

    Publicado 2024
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  20. 20
    Antitumor Activity of Sustained N-Myc Reduction in Rhabdomyosarcomas and Transcriptional Block by Antigene Therapy

    Antitumor Activity of Sustained N-Myc Reduction in Rhabdomyosarcomas and Transcriptional Block by Antigene Therapy por Roberto Tonelli, Alan McIntyre, Consuelo Camerin, Zoë S. Walters, Korinne Di Leo, Joanna Selfe, Stefania Purgato, Edoardo Missiaglia, Andrea Tortori, Jane Renshaw, Annalisa Astolfi, Kathryn R. Taylor, Salvatore Serravalle, Ryan T. Bishop, Cristina Nanni, Linda J. Valentijn, Andrea Faccini, Ivo Leuschner, Serena Formica, Jorge S. Reis‐Filho, Valentina Ambrosini, Khin Thway, Monica Franzoni, Brenda Summersgill, Rosangela Marchelli, Patrizia Hrelia, Giorgio Cantelli‐Forti, Stefano Fanti, Roberto Corradini, Andrea Pession, Janet Shipley

    Publicado 2011
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