Search Results - Ahmed Aman

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  1. 1
    Prolonged survival after surgical resection of cerebral metastasis from melanoma with multisystemic metastasis already present: a case report and literature review

    Prolonged survival after surgical resection of cerebral metastasis from melanoma with multisystemic metastasis already present: a case report and literature review by Hoz, Samer Saad, Alkhaleeli, Ahmed Aman, Aktham, Awfa

    Published 2018
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  2. 2
    Prolonged survival after surgical resection of cerebral metastasis from melanoma with multisystemic metastasis already present: a case report and literature review

    Prolonged survival after surgical resection of cerebral metastasis from melanoma with multisystemic metastasis already present: a case report and literature review by Hoz, Samer Saad, Alkhaleeli, Ahmed Aman, Aktham, Awfa

    Published 2017
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  3. 3
    The JAK2/STAT3 inhibitor pacritinib effectively inhibits patient-derived GBM brain tumor initiating cells in vitro and when used in combination with temozolomide increases survival in an orthotopic xenograft model

    The JAK2/STAT3 inhibitor pacritinib effectively inhibits patient-derived GBM brain tumor initiating cells in vitro and when used in combination with temozolomide increases survival... by Katharine V. Jensen, Orsolya Cseh, Ahmed Aman, Samuel Weiss, H. Artee Luchman

    Published 2017
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  4. 4
    Prevalence of painful diabetic peripheral neuropathy and its impact on quality of life among diabetic patients in Western region, Saudi Arabia

    Prevalence of painful diabetic peripheral neuropathy and its impact on quality of life among diabetic patients in Western region, Saudi Arabia by AlSufyani, Maram Hassan, Alzahrani, Abdullah M, Allah, Ahmed Aman, Abdullah, Rehab Ismail, Alzhrani, Sara Hasan, Alsaab, Adel Ali

    Published 2020
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  5. 5
    Metformin Pharmacokinetics in Mouse Tumors: Implications for Human Therapy

    Metformin Pharmacokinetics in Mouse Tumors: Implications for Human Therapy by Ryan J.O. Dowling, Sonya H.L. Lam, C. Bassi, Samar Mouaaz, Ahmed Aman, Taira Kiyota, Rima Al‐awar, Pamela J. Goodwin, Vuk Stambolic

    Published 2016
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  6. 6
    Picosecond Infrared Laser Desorption Mass Spectrometry Identifies Medulloblastoma Subgroups on Intrasurgical Timescales

    Picosecond Infrared Laser Desorption Mass Spectrometry Identifies Medulloblastoma Subgroups on Intrasurgical Timescales by Michael Woolman, Claudia M. Kuzan-Fischer, Isabelle Ferry, Taira Kiyota, Betty Luu, Megan Wu, David G. Muñoz, Sunit Das, Ahmed Aman, Michael D. Taylor, James T. Rutka, Howard J. Ginsberg, Arash Zarrine‐Afsar

    Published 2019
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  7. 7
    A genome-wide CRISPR/Cas9 screen in acute myeloid leukemia cells identifies regulators of TAK-243 sensitivity

    A genome-wide CRISPR/Cas9 screen in acute myeloid leukemia cells identifies regulators of TAK-243 sensitivity by Samir H. Barghout, Ahmed Aman, Kazem Nouri, Zachary Blatman, Karen Arevalo, Geethu Emily Thomas, Neil MacLean, Rose Hurren, Troy Ketela, Mehakpreet Saini, Moustafa Abohawya, Taira Kiyota, Rima Al‐awar, Aaron D. Schimmer

    Published 2021
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  8. 8
    Potent Targeting of the STAT3 Protein in Brain Cancer Stem Cells: A Promising Route for Treating Glioblastoma

    Potent Targeting of the STAT3 Protein in Brain Cancer Stem Cells: A Promising Route for Treating Glioblastoma by Sina Haftchenary, H. Artee Luchman, Andriana O. Jouk, Anthony J. Veloso, Brent D. G. Page, Xin Cheng, Sean S.H. Dawson, Natalie Grinshtein, Vijay Shahani, Kağan Kerman, David R. Kaplan, Carly Griffin, Ahmed Aman, Rima Al‐awar, Samuel Weiss, Patrick T. Gunning

    Published 2013
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  9. 9
    Virus-Tumor Interactome Screen Reveals ER Stress Response Can Reprogram Resistant Cancers for Oncolytic Virus-Triggered Caspase-2 Cell Death

    Virus-Tumor Interactome Screen Reveals ER Stress Response Can Reprogram Resistant Cancers for Oncolytic Virus-Triggered Caspase-2 Cell Death by Douglas J. Mahoney, Charles Lefebvre, Kristina J. Allan, J Brun, Cina A. Sanaei, Stephen Baird, Nelson Pearce, S. A.‐M. Grönberg, Brian C. Wilson, Mikael Prakesh, Ahmed Aman, Methvin Isaac, Ahmed Mamai, David Uehling, Rima Al‐awar, Theresa Falls, Tommy Alain, David F. Stojdl

    Published 2011
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  10. 10
    Small molecule epigenetic screen identifies novel EZH2 and HDAC inhibitors that target glioblastoma brain tumor-initiating cells

    Small molecule epigenetic screen identifies novel EZH2 and HDAC inhibitors that target glioblastoma brain tumor-initiating cells by Natalie Grinshtein, Constanza Rioseco, Richard Marcellus, David Uehling, Ahmed Aman, Xueqing Lun, Osamu Muto, Lauren Podmore, Jake Lever, Yaoqing Shen, Michael Blough, G. Cairncross, Stephen M. Robbins, Steven J.M. Jones, Marco A. Marra, Rima Al‐awar, Donna L. Senger, David R. Kaplan

    Published 2016
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  11. 11
    MYC Interacts with the G9a Histone Methyltransferase to Drive Transcriptional Repression and Tumorigenesis

    MYC Interacts with the G9a Histone Methyltransferase to Drive Transcriptional Repression and Tumorigenesis by William B. Tu, Yu-Jia Shiah, Corey Lourenco, Peter J. Mullen, Dharmendra Dingar, Cornelia Redel, Aaliya Tamachi, Wail Ba-Alawi, Ahmed Aman, Rima Al‐awar, David W. Cescon, Benjamin Haibe‐Kains, C.H. Arrowsmith, Brian Raught, Paul C. Boutros, Linda Z. Penn

    Published 2018
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  12. 12
    Disulfiram when Combined with Copper Enhances the Therapeutic Effects of Temozolomide for the Treatment of Glioblastoma

    Disulfiram when Combined with Copper Enhances the Therapeutic Effects of Temozolomide for the Treatment of Glioblastoma by Xueqing Lun, J. Connor Wells, Natalie Grinshtein, Jennifer C. King, Xiaoguang Hao, Ngoc-Ha Dang, Xiuling Wang, Ahmed Aman, David Uehling, Alessandro Datti, Jeffrey L. Wrana, Jacob C. Easaw, Artee Luchman, Samuel Weiss, J. Gregory Cairncross, David R. Kaplan, Stephen M. Robbins, Donna L. Senger

    Published 2016
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  13. 13
    Wnt Inhibitor Screen Reveals Iron Dependence of β-Catenin Signaling in Cancers

    Wnt Inhibitor Screen Reveals Iron Dependence of β-Catenin Signaling in Cancers by Siyuan Song, Tania Christova, Stephen Perusini, Solmaz Alizadeh, Ren-Yue Bao, Bryan W. Miller, Rose Hurren, Yulia Jitkova, Marcela Gronda, Methvin Isaac, Babu Joseph, Ratheesh Subramaniam, Ahmed Aman, Anh Chau, Donna E. Hogge, Scott J. Weir, James M. Kasper, Aaron D. Schimmer, Rima Al‐awar, Jeffrey L. Wrana, Liliana Attisano

    Published 2011
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  14. 14
    An Allosteric Inhibitor of Protein Arginine Methyltransferase 3

    An Allosteric Inhibitor of Protein Arginine Methyltransferase 3 by Alena Siarheyeva, Guillermo Senisterra, Abdellah Allali‐Hassani, Aiping Dong, E. Dobrovetsky, Gregory A. Wasney, Irene Chau, Richard Marcellus, Taraneh Hajian, Feng Liu, Ilia Korboukh, David Smil, Yuri Bolshan, Jinrong Min, Hong Wu, Hong Zeng, P. Loppnau, Gennadiy Poda, Carly Griffin, Ahmed Aman, Peter J. Brown, Jian Jin, Rima Al‐awar, C.H. Arrowsmith, Matthieu Schapira, Masoud Vedadi

    Published 2012
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  15. 15
    Molecular glues that inhibit deubiquitylase activity and inflammatory signaling

    Molecular glues that inhibit deubiquitylase activity and inflammatory signaling by Francesca Chandler, Adi Narayana Reddy Poli, Smita Bhutda, Rebecca L. Ross, Arindam Datta, Miriam Walden, Kieran Walker, Stefano Di Donato, Joel Cassel, Michaël Prakesch, Ahmed Aman, Alessandro Datti, Lisa J. Campbell, Martina Foglizzo, Lillie Bell, Dan J. Stein, James R. Ault, Rima Al‐awar, Antonio N. Calabrese, Frank Sicheri, Francesco Del Galdo, Joseph M. Salvino, Roger A. Greenberg, Elton Zeqiraj

    Published 2025
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  16. 16
    Catalytic site remodelling of the DOT1L methyltransferase by selective inhibitors

    Catalytic site remodelling of the DOT1L methyltransferase by selective inhibitors by Wenyu Yu, Emma J. Chory, Amy K. Wernimont, W. Tempel, Alex Scopton, Alexander Federation, Jason Marineau, Jun Qi, Dalia Baršytė-Lovejoy, Joanna Yi, Richard Marcellus, Roxana E. Iacob, John R. Engen, Carly Griffin, Ahmed Aman, Erno Wienholds, Fengling Li, Javier Pineda, Guillermina Estiú, Tatiana Shatseva, Taraneh Hajian, Rima Al‐awar, John E. Dick, Masoud Vedadi, Peter J. Brown, C.H. Arrowsmith, James E. Bradner, Matthieu Schapira

    Published 2012
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  17. 17
    Identification of triazenyl indoles as inhibitors of fungal fatty acid biosynthesis with broad-spectrum activity

    Identification of triazenyl indoles as inhibitors of fungal fatty acid biosynthesis with broad-spectrum activity by Kali R. Iyer, Sheena C. Li, Nicole M. Revie, Jennifer W. Lou, Dustin Duncan, Sara Fallah, Hiram Sánchez, Iwona Skulska, Mojca Mattiazzi Ušaj, Hamid Safizadeh, Brett Larsen, Cassandra J. Wong, Ahmed Aman, Taira Kiyota, Mami Yoshimura, Hiromi Kimura, Hiroyuki Hirano, Minoru Yoshida, Hiroyuki Osada, Anne‐Claude Gingras, David R. Andes, Rebecca S. Shapiro, Nicole Robbins, Mohammad T. Mazhab‐Jafari, Luke Whitesell, Yoko Yashiroda, Charles Boone, Leah E. Cowen

    Published 2023
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  18. 18
    Functional characterization of a PROTAC directed against BRAF mutant V600E

    Functional characterization of a PROTAC directed against BRAF mutant V600E by Ganna Posternak, Xiaojing Tang, Pierre Maisonneuve, Ting Jin, Hugo Lavoie, Salima Daou, Stephen Orlicky, Théo Goullet de Rugy, Lauren Caldwell, Kin Chan, Ahmed Aman, Michaël Prakesch, Gennady Poda, P. Mäder, Cassandra J. Wong, Stefan Maier, Julia Kitaygorodsky, Brett Larsen, Karen Colwill, Zhe Yin, Derek F. Ceccarelli, Robert A. Batey, Mikko Taipale, Igor Kurinov, David Uehling, Jeffrey L. Wrana, Daniel Durocher, Anne‐Claude Gingras, Rima Al‐awar, Marc Therrien, Frank Sicheri

    Published 2020
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  19. 19
    Pharmacological inhibition of PRMT7 links arginine monomethylation to the cellular stress response

    Pharmacological inhibition of PRMT7 links arginine monomethylation to the cellular stress response by Magdalena M. Szewczyk, Yoshinori Ishikawa, Shawna Organ, Nozomu Sakai, Fengling Li, Levon Halabelian, Suzanne Ackloo, Amber L. Couzens, Mohammad S. Eram, David Dilworth, Hideto Fukushi, Rachel Harding, Carlo C. dela Seña, Tsukasa Sugo, Kôzô Hayashi, David McLeod, Carlos Zepeda, Ahmed Aman, María Sánchez‐Osuna, Éric Bonneil, Shinji Takagi, Rima Al‐awar, Mike Tyers, Stéphane Richard, Masayuki Takizawa, Anne‐Claude Gingras, C.H. Arrowsmith, Masoud Vedadi, Peter J. Brown, Hiroshi Nara, Dalia Baršytė-Lovejoy

    Published 2020
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  20. 20
    ( <i>R</i> )-PFI-2 is a potent and selective inhibitor of SETD7 methyltransferase activity in cells

    ( <i>R</i> )-PFI-2 is a potent and selective inhibitor of SETD7 methyltransferase activity in cells by Dalia Baršytė-Lovejoy, Fengling Li, Menno J. Oudhoff, John H. Tatlock, Aiping Dong, Hong Zeng, Hong Wu, Spencer A. Freeman, Matthieu Schapira, Guillermo Senisterra, Ekaterina Kuznetsova, Richard Marcellus, Abdellah Allali‐Hassani, Sidney H. Kennedy, Jean‐Philippe Lambert, Amber L. Couzens, Ahmed Aman, Anne‐Claude Gingras, Rima Al‐awar, Paul V. Fish, Brian S. Gerstenberger, Lee R. Roberts, Caroline Benn, Rachel L. Grimley, Mitchell J.S. Braam, Fábio Rossi, Marius Sudol, Peter J. Brown, Mark E. Bunnage, Dafydd R. Owen, Colby Zaph, Masoud Vedadi, C.H. Arrowsmith

    Published 2014
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